• 대한세포병리학회지
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• 제10권1호
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• pp.85-89
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• 1999

An extremely unusual case of epidermoid cyst showing diffuse parakeratosis and aggressive clinical behavior is presented. A destructive bone lesion with surrounding ill-defined soft tissue lesion was found by computed tomography in a 63 year-old man complaining of painful swelling of the right buttock. He had a history of surgical excision twice for epidermoid cysts of soft tissue of the right hip during recent one year On aspiration cytology, the aspirate was highly cellular and mostly composed of desquamated nucleated squamous cells. Operation finding revealed that the iliac bone was Irregularly destroyed and filled with gray-white cheesy material and necrotic bone bedris. Adjacent gluteus muscle showed scattered gray-white lesions. The curettage specimen showed bone necrosis and desquamated squamous cells filling the marrow spaces. The lesion within muscle revealed epidermoid cyst with diffuse parakeratosis.

• Asian-Australasian Journal of Animal Sciences
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• 제27권8호
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• pp.1204-1210
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• 2014

The objective of the study was to investigate the effect of feeding fibrous diets on growth performance and occurrence of aggressive behaviours in growing pigs. Sixty healthy castrated pigs (initial body weight: $46.7{\pm}4.35$ kg) were used. A basal diet was diluted with maize cobs to two levels (0 and 160 g/kg dry matter). Behavioural activities were observed using video cameras for three weeks, 8 h/d starting at 0800 h. Pigs subjected to control diet gained more weight compared to pigs receiving fibrous diet in week 1 (0.47 vs 0.15 kg, respectively) and 2 (1.37 vs 1.04, respectively) (p<0.05). Average daily gain was not affected by treatment diet in the third week. Pigs on high fibrous spent more time eating, lying down, standing, walking and fighting (p<0.05) compared to pigs on control diet. Time spent eating increased as the weeks progressed whilst time spent lying down decreased. Time of day had an effect on time spent on different behavioural activities exhibited by all pigs on different treatment diet (p<0.05). Inactivity was greatest in 5th (1200 to 1300 h) hour of the day for all the pigs on different dietary treatments. Skin lesions appeared the most on neck and shoulder region followed by chest, stomach and hind leg region, and finally head region (p<0.05). Pigs on high fibre diet had more skin lesions in all body regions compared to pigs on control diet (p<0.05). It can be concluded that the high fibrous diet with maize cobs did not affect growth performance and also did not reduce aggressive behaviours. Aggressive behaviours emanated out of frustration when queuing on the feeder. The findings of this study suggest that maize cobs can be included at a level of 160 g/kg in diets of pigs. However, to reduce the level of aggression more feeding space should be provided.

• 대한골관절종양학회지
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• 제9권1호
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• pp.77-83
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• 2003

공격성 섬유종증은 비교적 드문 연부 조직 종양이지만, 국소 증식 및 침윤성이 강한 종양으로 알려져 있다. 그렇지만 종양 증식에 관한 정확한 기전은 아직 보고되어 지지 않고 있다. 한편, 종양 억제 유전자 PTEN은 국소 침윤성과 전이를 보이는 여러 암 조직에서 발현의 감소 또는 돌연 변이가 보고되고 있다. 본 연구에서는 공격성 섬유종증에서 면역조직화학적 염색과 면역탁본법을 통해 종양 억제 유전자 PTEN의 발현의 양상을 알아보고자 하였다. 면역 탁본법과 면역조직화학적 염색상 PTEN의 발현은 정상 근막 조직에서는 균일하게 발현되었으나, 공격성 섬유종증 종양조직에서는 발현이 감소하였다. 공격성 섬유종증에서 PTEN발현의 감소는 급속한 증식과 재발 및 주위 조직의 침윤이 특징인 공격성 섬유종증의 병인에 관련이 있을 것으로 사료된다.

• 한국사회복지학
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• 제68권1호
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• pp.225-248
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• 2016

본 연구는 서울시립교향악단의 "우리동네 오케스트라 학습영향평가"를 위해 수집된 종단 자료를 사용하여 지역사회를 기반으로 운영하는 오케스트라 교육 활동이 빈곤아동의 발달에 미치는 효과와 그 효과를 촉진하는 오케스트라 교육 활동 요소를 살펴보고자 수행되었다. 이를 위해 빈곤 아동의 발달부분인 우울, 공격성, 공동체성, 대인관계와 오케스트라 교육 활동 효과를 촉진시키는 활동요소인 평가, 만족, 외부의 관심과 참여를 주요 변수로 구성하여 오케스트라 교육 활동과 빈곤아동발달에 관한 잠재성장 모형 분석을 실시하였다. 분석결과, 오케스트라 교육 활동 효과로 빈곤아동의 우울, 공격성, 대인관계에 의미 있는 긍정적 발달을 보였다. 또한 아동발달궤적의 조건모형에서 음악평가는 공동체성의 변화율에, 태도평가는 우울과 공격성, 공동체성의 초기치에 긍정적인 영향을 미쳤으며, 만족은 공동체성과 대인관계의 초기치에 긍정적 영향을 미치는 것으로 나타났다. 부모 관심과 참여는 공격성 초기치에 부정적 영향을, 지역사회 관심과 참여는 우울과 공격성 초기치에 긍정적 영향을 미치는 것으로 나타났다. 본 연구결과를 바탕으로 오케스트라 교육 활동에 참여하는 빈곤아동의 발달에 관한 이해를 돕고 사회복지사의 직접적인 개입의 실천적 근거를 제공하고, 사회복지계, 문화예술계, 교육계 등의 빈곤층 문화예술교육의 새로운 방안을 모색하여 빈곤아동 발달의 증진에 기여하고자 한다.

• 한국안전학회지
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• 제13권4호
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• pp.113-120
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• 1998

Fatigue crack growth rates(i.e. crack initiation and crack growth of short and long crack) are investigated using commercial plates of high strength Al alloy 7075-T651 for the transverse-longitudinal(T-L) direction in air, water and sea water. Also, the evaluation direct current potential drop(D.C.P.D) method and the fractographical analysis by SEM are carried out. Near threshold region, short crack growth rates were much faster than those of comparable long cracks, and these short crack growth rates actually decrease with increasing crack growth and eventually merge with long crack data. Fatigue crack propagation rates in aggressive media(i.e. sea water) increase noticeably over three times those in air. One of the most significant characters in this phenomenon as a corrosion-fatigue causes an acceleration in crack growth rates. Sea water environment, particularly Cl$^{[-10]}$ solution brings the most detrimental effects to aluminum alloy. The result of fractographical morphology in air, water and sea water by SEM shows obvious dimpled rupture and typical striation in air, but transgranular fracture surface in water and sea water.

• 임상이비인후과
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• 제29권2호
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• pp.281-285
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• 2018

Columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is a rare variant representing 0.15-0.2% of all PTCs. The CCV is aggressive, due to its rapid growth, high local recurrence rate, and frequent lung, brain and bone metastasis. Aggressive surgical and medical management are recommended for these neoplasias. The authors experienced a case of CCV-PTC in a 45-year-old man. We performed total thyroidectomy with neck dissection. The patient received radiation and radioactive iodine therapy. There were no recurrences or complications in the following 24 months after the operation. The patient will closely undergo continuous follow up. We present the clinical characteristics, pathology, treatment, and prognosis of the tumor with a review of the literature.

• Journal of Chest Surgery
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• 제27권7호
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• pp.634-638
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• 1994

Infection of a median sternotomy incision may result in a large, unsightly,unstable,and potentially fatal wound. During the past 8 years, 5 consecutive patients [ 4 male and 1 female ] had repair of infected sternotomy wound. We describe our current preferred techniques and the results we have achieved with them. As soon as the sternal infection was shown, operative wound was opened and irrigated more than 4 times a day with 0.5% Betadine iodine solution until the exudate became clean with no growth of bacteria. Operation was performed in one-stage, which consisted of aggressive debridement of the infected bone and muscle transposition. Reconstruction was with one-side or both pectoralis flaps in all patients and rectus abdominis in 2 patients. There was no mortality or morbidity within 30 days postoperatively. We conclude that early aggressive debridement and muscle transposition remain the treatment of choice for most patients with infected median sternotomy wounds.

• Clinical and Experimental Pediatrics
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• 제59권12호
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• pp.466-470
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• 2016

Early, aggressive nutrition is an important contributing factor of long-term neurodevelopmental outcomes. To ensure optimal growth in premature infants, adequate protein intake and optimal protein/energy ratio should be emphasized rather than the overall energy intake. Minimal enteral nutrition should be initiated as soon as possible in the first days of life, and feeding advancement should be individualized according to the clinical course of the infant. During hospitalization, enteral nutrition with preterm formula and fortified human milk represent the best feeding practices for facilitating growth. After discharge, the enteral nutrition strategy should be individualized according to the infant's weight at discharge. Infants with suboptimal weight for their postconceptional age at discharge should receive supplementation with human milk fortifiers or nutrient-enriched feeding, and the enteral nutrition strategy should be reviewed and modified continuously to achieve the target growth parameters.

• Clinical and Experimental Pediatrics
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• 제58권3호
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• pp.77-83
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• 2015

Relative to a fetus of the same gestational age, very low birth weight (VLBW) infants are more likely to be underfed and to undergo growth restriction during their early hospital stay. The current trend towards "early and aggressive" nutritional strategies in VLBW infants aims to overcome the early nutritional deficiency and thereby boost postnatal catch-up growth, simultaneously improving long-term neurodevelopmental outcomes. Although the minimum starting amino acid (AA) dose to prevent negative nitrogen balance is well established, the upper limit and the rate of increase of early AA doses are controversial. Most randomized controlled trials show that early and high-dose (target, 3.5 to 4.9 g/kg/day) AA regimens, with or without high nonprotein calories, do not improve long-term growth and neurodevelopment. High-dose AA supplementation may lead to early metabolic disturbances and excessive or disproportionate plasma AA levels, particularly in infants of very low gestational age. Further large studies are needed to clarify the optimal strategy for early administration of parenteral AA doses in VLBW infants.

• 한국축산시설환경학회지
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• 제1권2호
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• pp.137-144
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• 1995

두당 돈방면적과 돈군의 크기 등 돼지의 사육환경 조건이 자돈의 성장과 행동에 미치는 영향을 구명하기 위하여 이유후부터 체중 30kg까지의 자돈을 총 18돈방에 300두를 공시하여 시험하였다. 사료급여는 습식급여로 하였으며 두당 돈방 면적은 0.18$m^2$, 0.23$m^2$ 및 0.30$m^2$로 하였고 돈군의 크기는 돈방당 15두, 20두 및 25두로 하였다. 일당증체량, 일당사료섭취량 및 사료요구율을 조사하였으며 자돈의 행동을 휴식, 섭취, 공격, 사회성 및 유희행동으로 나누어 조사분석하였으며 그 결과를 요약하면 다음과 같다. 1. 두당 돈방면적이 0.18$m^2$의 경우 사료섭취량은 많았으나(p<0.01) 증체량은 차이가 없고, 사료효율은 낮으므로(p<0.05) 두당 0.23$m^2$의 경우가 최적인 것으로 나타났다. 2. 돈군의 크기에 따른 자돈의 증체나 사료효율에는 차이가 없었으며 사료섭취량은 15두군이 가장 많았다(p<0.01). 3. 자돈의 두당 돈방면적은 행동에 크게 영향을 미치며 두당 돈방면적이 좁을수록 공격행동이 증가되었고, 휴식, 사회성 및 유희행동은 감소되었다(p<0.01). 4. 돈군의 크기는 자돈의 행동에 큰 영향을 미치지 않았으나, 유희행동은 돈군이 커질수록 감소되었다(p<0.01). 5. 자돈의 성장과 행동면에서 두당 0.23$m^2$의 돈방면적을 부여하고 20~25두 크기로 돈군을 유지하는 것이 최적인 것으로 나타났다.