• Title/Summary/Keyword: Aggressive growth

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Fine Needle Aspiration Cytology of Unusual Epidermoid Cyst with Diffuse Parakeratosis and Aggressive Growth - A Case Report - (미만성 이상각화증을 동반한 침습성 표피양 낭의 세침흡인 세포학적 소견 - 1예 보고 -)

  • Nam, Hae-Joo
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.85-89
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    • 1999
  • An extremely unusual case of epidermoid cyst showing diffuse parakeratosis and aggressive clinical behavior is presented. A destructive bone lesion with surrounding ill-defined soft tissue lesion was found by computed tomography in a 63 year-old man complaining of painful swelling of the right buttock. He had a history of surgical excision twice for epidermoid cysts of soft tissue of the right hip during recent one year On aspiration cytology, the aspirate was highly cellular and mostly composed of desquamated nucleated squamous cells. Operation finding revealed that the iliac bone was Irregularly destroyed and filled with gray-white cheesy material and necrotic bone bedris. Adjacent gluteus muscle showed scattered gray-white lesions. The curettage specimen showed bone necrosis and desquamated squamous cells filling the marrow spaces. The lesion within muscle revealed epidermoid cyst with diffuse parakeratosis.

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Growth Performance and Behaviour in Grouped Pigs Fed Fibrous Diet

  • Bakare, A.G.;Madzimure, J.;Ndou, S.P.;Chimonyo, M.
    • Asian-Australasian Journal of Animal Sciences
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    • v.27 no.8
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    • pp.1204-1210
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    • 2014
  • The objective of the study was to investigate the effect of feeding fibrous diets on growth performance and occurrence of aggressive behaviours in growing pigs. Sixty healthy castrated pigs (initial body weight: $46.7{\pm}4.35$ kg) were used. A basal diet was diluted with maize cobs to two levels (0 and 160 g/kg dry matter). Behavioural activities were observed using video cameras for three weeks, 8 h/d starting at 0800 h. Pigs subjected to control diet gained more weight compared to pigs receiving fibrous diet in week 1 (0.47 vs 0.15 kg, respectively) and 2 (1.37 vs 1.04, respectively) (p<0.05). Average daily gain was not affected by treatment diet in the third week. Pigs on high fibrous spent more time eating, lying down, standing, walking and fighting (p<0.05) compared to pigs on control diet. Time spent eating increased as the weeks progressed whilst time spent lying down decreased. Time of day had an effect on time spent on different behavioural activities exhibited by all pigs on different treatment diet (p<0.05). Inactivity was greatest in 5th (1200 to 1300 h) hour of the day for all the pigs on different dietary treatments. Skin lesions appeared the most on neck and shoulder region followed by chest, stomach and hind leg region, and finally head region (p<0.05). Pigs on high fibre diet had more skin lesions in all body regions compared to pigs on control diet (p<0.05). It can be concluded that the high fibrous diet with maize cobs did not affect growth performance and also did not reduce aggressive behaviours. Aggressive behaviours emanated out of frustration when queuing on the feeder. The findings of this study suggest that maize cobs can be included at a level of 160 g/kg in diets of pigs. However, to reduce the level of aggression more feeding space should be provided.

Expression of PTEN, Tumor Suppressor Protein, in Aggressive Fibromastosis (공격성 섬유종증에서 PTEN 종양 억제 인자의 발현)

  • Kim, Jung-Ryul
    • The Journal of the Korean bone and joint tumor society
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    • v.9 no.1
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    • pp.77-83
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    • 2003
  • Aggressive fibromatosis is a rare soft tissue tumor with locally invasive and infiltrative characteristics. The mechanism of this invasive nature was not reported until now. Mutations or reduction of PTEN, tumor suppressor gene, in cancer tissues, have been found to be associated with invasiveness and metastatic properties of cancer cells. To know the pattern of expression of PTEN in aggressive fibromatosis, we analysed the expression of PTEN with immunohistochemical stain and immunoblotting. PTEN was homogeneously expressed in the normal musculoaponeurotic tissues, but absent or very faint in tissues of patients with aggressive fibromatosis as evidenced by western blot analysis and immunohistochemical examinations. Although the meaning of decreased PTEN expression in aggressive fibromatosis is not certain, it might be involved in the growth of the aggressive fibromatosis, and associated with phenotype of aggressive fibromatosis.

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Community Orchestra Educational Activities and Development of Poor Children (지역사회 오케스트라 교육 활동과 빈곤아동 발달)

  • An, Eunmi
    • Korean Journal of Social Welfare
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    • v.68 no.1
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    • pp.225-248
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    • 2016
  • This study explores the effects on development of poor children by community-based orchestra educational activities and the orchestra educational activities factors for promoting the effects using longitudinal data are those collected for "The Evaluation of the Impact of Our Neighborhood Orchestra on Children's Learning" made by the Seoul Philharmonic Orchestra. For these purposes, this study employed a latent growth model analysis of the factors such as depression, aggressive behavior, communality and interpersonal relationship of development of poor children and evaluation, satisfaction, outsiders'attention and participation of facilitative factors. The result shows that they displayed significantly positive development in depression, aggressive behavior, and interpersonal relationship. It appears that the evaluation on music achievement had a positive impact on the rate of change in communality, while the evaluation on attitude had an impact in the initial value of depression, aggressive behavior, and communality, also the sense of satisfaction had a positive impact on the initial value of communality and interpersonal relationship in conditional models. And parents' attention and participation had a negative impact on the initial value of aggressive behavior, while the attention and participation of the community showed a positive impact on the initial value of depression and aggressive behavior. Based on these results, this study attempted to broaden the understanding of the development of poor children taking part in orchestra-based educational activities and provide a practical basis for social workers' direct invention, and look for new ways by shedding light on the merits of the cultural/art education of poor children that engage in the community-based orchestra educational activities.

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A Study on Corrosion Fatigue Crack Growth Behavior in Al-Alloy 7075-T651 (I) (Al-Alloy 7075-T651의 부식피로균열 성장거동에 관한 연구(I))

  • 김봉철;한지원;우흥식
    • Journal of the Korean Society of Safety
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    • v.13 no.4
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    • pp.113-120
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    • 1998
  • Fatigue crack growth rates(i.e. crack initiation and crack growth of short and long crack) are investigated using commercial plates of high strength Al alloy 7075-T651 for the transverse-longitudinal(T-L) direction in air, water and sea water. Also, the evaluation direct current potential drop(D.C.P.D) method and the fractographical analysis by SEM are carried out. Near threshold region, short crack growth rates were much faster than those of comparable long cracks, and these short crack growth rates actually decrease with increasing crack growth and eventually merge with long crack data. Fatigue crack propagation rates in aggressive media(i.e. sea water) increase noticeably over three times those in air. One of the most significant characters in this phenomenon as a corrosion-fatigue causes an acceleration in crack growth rates. Sea water environment, particularly Cl$^{[-10]}$ solution brings the most detrimental effects to aluminum alloy. The result of fractographical morphology in air, water and sea water by SEM shows obvious dimpled rupture and typical striation in air, but transgranular fracture surface in water and sea water.

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A Case of Columnar Cell Variant of Papillary Thyroid Carcinoma (갑상선 유두암 원주세포변형 1예)

  • Choe, Si Hong;Lee, Donghoo;Jung, Soo Jin;Kim, Do Hun
    • Journal of Clinical Otolaryngology Head and Neck Surgery
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    • v.29 no.2
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    • pp.281-285
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    • 2018
  • Columnar cell variant of papillary thyroid carcinoma (CCV-PTC) is a rare variant representing 0.15-0.2% of all PTCs. The CCV is aggressive, due to its rapid growth, high local recurrence rate, and frequent lung, brain and bone metastasis. Aggressive surgical and medical management are recommended for these neoplasias. The authors experienced a case of CCV-PTC in a 45-year-old man. We performed total thyroidectomy with neck dissection. The patient received radiation and radioactive iodine therapy. There were no recurrences or complications in the following 24 months after the operation. The patient will closely undergo continuous follow up. We present the clinical characteristics, pathology, treatment, and prognosis of the tumor with a review of the literature.

Management of Infected Median Sternotomy Wound by Muscle Flap -5 cases- (근육편에 의한 정중 흉골절개 감염의 치료 -5례 치험-)

  • Kim, Hyeong-Gon;Jo, Seon-Hwan;Choe, Jong-Beom
    • Journal of Chest Surgery
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    • v.27 no.7
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    • pp.634-638
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    • 1994
  • Infection of a median sternotomy incision may result in a large, unsightly,unstable,and potentially fatal wound. During the past 8 years, 5 consecutive patients [ 4 male and 1 female ] had repair of infected sternotomy wound. We describe our current preferred techniques and the results we have achieved with them. As soon as the sternal infection was shown, operative wound was opened and irrigated more than 4 times a day with 0.5% Betadine iodine solution until the exudate became clean with no growth of bacteria. Operation was performed in one-stage, which consisted of aggressive debridement of the infected bone and muscle transposition. Reconstruction was with one-side or both pectoralis flaps in all patients and rectus abdominis in 2 patients. There was no mortality or morbidity within 30 days postoperatively. We conclude that early aggressive debridement and muscle transposition remain the treatment of choice for most patients with infected median sternotomy wounds.

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Enteral nutrition for optimal growth in preterm infants

  • Kim, Myo-Jing
    • Clinical and Experimental Pediatrics
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    • v.59 no.12
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    • pp.466-470
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    • 2016
  • Early, aggressive nutrition is an important contributing factor of long-term neurodevelopmental outcomes. To ensure optimal growth in premature infants, adequate protein intake and optimal protein/energy ratio should be emphasized rather than the overall energy intake. Minimal enteral nutrition should be initiated as soon as possible in the first days of life, and feeding advancement should be individualized according to the clinical course of the infant. During hospitalization, enteral nutrition with preterm formula and fortified human milk represent the best feeding practices for facilitating growth. After discharge, the enteral nutrition strategy should be individualized according to the infant's weight at discharge. Infants with suboptimal weight for their postconceptional age at discharge should receive supplementation with human milk fortifiers or nutrient-enriched feeding, and the enteral nutrition strategy should be reviewed and modified continuously to achieve the target growth parameters.

Nutritional strategy of early amino acid administration in very low birth weight infants

  • Lee, Byong Sop
    • Clinical and Experimental Pediatrics
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    • v.58 no.3
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    • pp.77-83
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    • 2015
  • Relative to a fetus of the same gestational age, very low birth weight (VLBW) infants are more likely to be underfed and to undergo growth restriction during their early hospital stay. The current trend towards "early and aggressive" nutritional strategies in VLBW infants aims to overcome the early nutritional deficiency and thereby boost postnatal catch-up growth, simultaneously improving long-term neurodevelopmental outcomes. Although the minimum starting amino acid (AA) dose to prevent negative nitrogen balance is well established, the upper limit and the rate of increase of early AA doses are controversial. Most randomized controlled trials show that early and high-dose (target, 3.5 to 4.9 g/kg/day) AA regimens, with or without high nonprotein calories, do not improve long-term growth and neurodevelopment. High-dose AA supplementation may lead to early metabolic disturbances and excessive or disproportionate plasma AA levels, particularly in infants of very low gestational age. Further large studies are needed to clarify the optimal strategy for early administration of parenteral AA doses in VLBW infants.

Effects of Environmental Factors on Growth Performances and Behavioural Patterns of Weanling Pigs (環境條件이 仔豚의 成長과 行動에 미치는 影響)

  • 김두환;김철욱;송영민;진상근
    • Journal of Animal Environmental Science
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    • v.1 no.2
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    • pp.137-144
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    • 1995
  • This experiment was conducted to determine the effects of non-climatic environmental factors on growth performances and behavioural patterns of weanling pigs. Three hundred and sixty weanling pigs were contained and carried out with three levels of spaces per pig(0.18, 0.23 and 0.30$m^2$) and three different numbers of pigs per pen(15, 20 and 25 pigs) up to 30kg body weight. Designed by using a 3 $\times$ 3 factorial arrangement(three levels of spaces $\times$ three different numbers of pigs). This experiment investigated the effects of main factors and the relationship between each factors. The result of this experiment were summarized as follows ; 1. The reduction of floor space caused the reduction of feed/gain in the weanling pigs. Pigs responded with the increased feed intake(p<0.01) and with no change in body weight gain. 2. There were no significant differences in the body weight gain and feed/gain in weanling pigs by changing group sizes, but group size affected the feed intake significantly(p<0.01). 3. Space allowance affected the behavioural patterns significantly(p<0.01) of weanling pigs. The reduction of floor space caused the increment of aggressive behaviour and weanling pigs responded with the decreased resting, non aggressive social and play behaviour. 4. There were no significant differences in the resting, eating, aggressive and non aggressive social behaviour in weanling pigs by changing group sizes, but the large group size caused the reduction of play behaviour in the weanling pigs(p<0.01). 5. Therefore we concluded that weanling pigs require 0.23$m^2$ per pig and 20~25 pigs per pen for the better environment condition.

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