• Journal of the Korean Society of Food Science and Nutrition
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• v.34 no.9
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• pp.1320-1324
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• 2005

Soybean (Glycine max L.) is an increasingly important food source and functional food. Platelet aggregation plays an important role in thrombogenesis and atherosclerosis. Here, we studied the anti-platelet aggregating effects of solvent extracts from Korean soybean varieties and isoflauone derivatives. Nine Korean soybean varieties were extracted by solvents (methanol and buthanol and their extracts was investigated for the inhibition against tile aggregation of washed rabbit platelets induced by collagen or thrombin. Maximal inhibition of buthanol extracts against platelet aggregation induced by collagen was $95\%$ in Black-kong and Jinpum - kong. The potency of their inhibition was in the following order : Black > Jinpum > Bokwang > Hwangkum > Pureun > Malli > Danbaek > Danyeob > Jangsu - kong. The Black - kong only seemed to produce the maximal inhibition against platelet aggregation induced by thrombin. Total isoflavone content measured was Jinpum-kong ($1347.8{\mu}g/g$) and Black-kong ($918.7{\mu}g/g$). Maximal inhibition of isoflavone derivatives against platelet aggregation induced by collagen was $97\%$ in genistein. The potency of their inhibition was in the following order: genistein>daidzein>genistin. The isoflavone derivatives did not affect the platelet aggregation induced by thrombin. However, Black-kong cortex seemed to Produce the optimal inhibition against platelet aggregation induced by collagen. These results suggest that Black-kong and Jinpum-kong may be a good source for antiplatelet agents, and their antiplatelet effect be related to tile content and the chemical structure with the number of -OH group and the attached glycoside in the isoflavone derivative.

• Journal of Ginseng Research
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• v.9 no.1
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• pp.15-23
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• 1985

The study was carried out to confirm the changes of soil physico-chemical properties and population of Fusarium solani by soil managements at preplanning fields for ginseng cultivation. Soil porosity and aggregation had been significantly increased during the managements while exchangeable nitrogen content and bulk density of the soil had been decreased. Available phosphate and exchangeable potassium content, in addition, seemed to be slightly increased. And soil aggregation showed positive correlation with clay, organic matter, soil moisture, and Ca content in the soil but negative with K content. Decrease rate of NH4-N and NO3-N content after soil managements were 55% and 41% in average, respectively. And better decrease effect for NH4-N was obtained in sand loam soil whereas no effect for NO3-N with soil textures. The more ploughing seemed to result in less propagules of F solani in the soil, however there was non significant decrease in population of the pathogen after the soil management. Number of F. solani in soil was significantly less in the fields where gramineous and leguminous crops had been grown as a precrop than other crops tested. Meanwhile there was no correlation between soil texture and population of the pathogen in the soil.

• Journal of the Korean Operations Research and Management Science Society
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• v.22 no.1
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• pp.123-140
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• 1997

In this paper we consider closed flow line systems with samploing inspections. The total number of parts in the system is assumed to be N. The processings carried out of each station do not always meet the requirement of quality. Therefore, upon completion of its processing at each station, a part is inspected to determine whether the processings meet the requirement of quality or not. We assume that inspection are done on a random basis. If a part is found to be defective by an inspection, it is fed back to the apropriate station. Two different cases will be considered in this study : a three-station flow line system with infinite buffers and a two-station flow line system with finite buffers. For each case, we will develop an exact method to obtain the performance measures such as throughput, machinen utilization, average outgoing quality and manufacturing lead time. For the case of the two-station flow line system ith finite buffers, we will also develop an approximation method using a stage-aggregation technique. Then using buffers, we will also develop an approximation method using a stage-aggregation technique. Then using these results, we will try to find an optimal inspection policy which maximizes the expected net profit under a certain cost structure. Although we present the results only for the two or three station flow line system in this paper, the results obtained in this paper can be extended easily to the system which consists of more than two or three stations.

• Proceedings of the KIEE Conference
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• 1999.11b
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• pp.273-275
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• 1999

This paper presents a dynamic equivalencing method in large electric power system for stability analysis. This method of modeling simplified equivalents for parts of the network outside the study area is to evaluate the stability of a study area modeled in detail. Generators are closely coupled in an electrical sense tend to swing together in groups during disturbances, and this behavior can be exploited to reduce the size of the power system model. The characteristics of generators swing together are referred to as coherency Coherency groups whose generators state trajectory are similar to the other generators state trajectory in the same coherency group by a certain disturbance. In this paper, procedures for forming dynamic equivalents of control devices of coherency-based generating units are proposed and the aggregation of the control devices such as excitation system and governor-turbine system is accomplished by this method. This method can deal with the aggregation of the same type of control devices and combination of hydro and steam unit or the many types of excitation systems. etc. This method is shown to be efficient in reducing the number of control device of generating units with small error in the study group by result of case study presented latter part of this paper.

• Proceedings of the KSRS Conference
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• 2007.10a
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• pp.612-615
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• 2007

Water quality modelling is an ideal tool of simulating physical, chemical and biological changes occurring in water systems. It has been utilized in a number of GIS-based water quality management and analysis applications. However, there is a need of a decision making process to translate the modelling result into an understandable form thereby implement the modelling results to the real world. This paper outlines a new water quality index called the QUAL2E's water quality index (QWQI) based on the water quality modelling using QUAL2E. The development mainly includes four steps: variable selection, sub-index development, weight assignment and sub-index aggregation. An experiment of applying the index and GIS to the Sapgyo River in Korea was implemented. Different from other water quality indices for general water uses, the index is specifically used for the simulated water quality indicators. The index can provide a simple and easy-to-understand decision support. Furthermore, interfacing with GIS, the decision analysis can be performed within a spatial environment. However, more study needs to be made in the future including the improvement of aggregation function.

• BMB Reports
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• v.38 no.3
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• pp.259-265
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• 2005

Proteins must fold into their correct three-dimensional conformation in order to attain their biological function. Conversely, protein aggregation and misfolding are primary contributors to many devastating human diseases, such as prion-mediated infections, Alzheimer's disease, type II diabetes and cystic fibrosis. While the native conformation of a polypeptide is encoded within its primary amino acid sequence and is sufficient for protein folding in vitro, the situation in vivo is more complex. Inside the cell, proteins are synthesized or folded continuously; a process that is greatly assisted by molecular chaperones. Molecular chaperones re a group of structurally diverse and mechanistically distinct proteins that either promote folding or prevent the aggregation of other proteins. With our increasing understanding of the proteome, it is becoming clear that the number of proteins that can be classified as molecular chaperones is increasing steadily. Many of these proteins have novel but essential cellular functions that differ from that of more 'conventional' chaperones, such as Hsp70 and the GroE system. This review focuses on the emerging role of molecular chaperones in protein quality control, i.e. the mechanism that rids the cell of misfolded or incompletely synthesized polypeptides that otherwise would interfere with normal cellular function.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.12A
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• pp.984-993
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• 2011

In this paper, we present a new method for efficient mobility management in infrastructure-based ad hoc networks. This type of network inherently takes the tree topology model in which an Internet gateway (IG) becomes a root. Accordingly, the nodes near the IG process get much more number of messages, thereby causing a bottleneck phenomenon that degrades network performance. This problem is known as a funneling effect. We present a method to maximize message aggregation in which the nodes in the networks form tree topology and perform skewed time synchronization according to the depths of the nodes during the tree construction process. We proved by resorting to simulation that the funneling effect is alleviated and network performance is improved greatly.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.9
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• pp.3034-3055
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• 2014

Wireless Sensor Networks have extensively been utilized for ambient data collection from simple linear structures to dense tiered deployments. Issues related to optimal resource allocation still persist for simplistic deployments including linear and hierarchical networks. In this work, we investigate the case of dimensioning parameters for linear and tiered wireless sensor network deployments with notion of providing extended lifetime and reliable data delivery over extensive infrastructures. We provide a single consolidated reference for selection of intrinsic sensor network parameters like number of required nodes for deployment over specified area, network operational lifetime, data aggregation requirements, energy dissipation concerns and communication channel related signal reliability. The dimensioning parameters have been analyzed in a pipeline monitoring scenario using ZigBee communication platform and subsequently referred with analytical models to ensure the dimensioning process is reflected in real world deployment with minimum resource consumption and best network connectivity. Concerns over data aggregation and routing delay minimization have been discussed with possible solutions. Finally, we propose a node placement strategy based on a dynamic programming model for achieving reliable received signals and consistent application in structural health monitoring with multi hop and long distance connectivity.

• Bulletin of the Korean Chemical Society
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• v.10 no.5
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• pp.437-442
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• 1989

The cmc's of sodium dodecyl sulfate (SDS)/Triton X-100 surfactant mixtures were determined by surface tension measurement at various surfactant compositions. The cmc values were lower than those predicted from ideal mixture. The regular solution theory was applied to calculate the interaction parameter, micellar composition, and the activity coefficients of surfactants in the mixed micelle. The interaction parameter (${\beta}$) was - 2.1. The nonideality arised largely from decreased activity of SDS in the mixed micelle. The mean aggregation numbers (${\bar{n}}$) and micropolarity of hydrocarbon region of the mixed micelles were determined by luminescence probe techniques. The total aggregation number (${\bar{n}}_{SDS}+{\bar{n}}_{TX}$) in mixed micelles showed little dependency on the composition of the micelle. The apparent dielectric constant of the hydrocarbon region of the micelle vs micellar composition plot showed positive deviation from linearity. Emission and emission quenching of excited tris(2,2'-bipyridine)ruthenium(Ⅱ) cation, $(Ru(bpy)_3^{2+})$, by methylviologen ($MV^{2+}$) were also investigated in the mixed micellar solutions. The quenching rate was lowest when the mole fraction of SDS in the surfactant mixtures (${\alpha}_{SDS}$) is about 0.25 and highest at ${\alpha}_{SDS}$ = 0.85. This was explained in terms of combined effects of binding of the cations with the micelle and mobility of the bound cations on the surface of the micelles.

• Journal of Lipid and Atherosclerosis
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• v.7 no.2
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• pp.88-97
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• 2018

The prevalence of atherothrombotic disease continues to rise, presenting an increasing number of challenges to modern society and creating interest in functional foods. Platelet activation, adhesion, and aggregation at vascular endothelial disruption sites are key events in atherothrombotic disease. Physiological challenges such as hyperlipidemia, obesity, and cigarette smoking are associated with vascular changes underlying platelet aggregation and inflammatory processes. However, it is difficult to determine the beneficial response of functional foods in healthy subjects. To address this problem, challenge models and high-risk models related to smokers, obesity, and dyslipidemia are proposed as sensitive measures to evaluate the effects of functional foods in healthy subjects. In this review, we construct a model to evaluate the effects of functional food such as natural products on blood flow based on a human intervention study.