• Journal of Ginseng Research
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• 제19권3호
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• pp.206-211
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• 1995

This study was investigated to find the effects of petroleum ether extract (Lipophilic fraction) from Korean red ginseng on platelet aggregation and thrombin time of the plasma in two groups of the experimental rats. One group of rats were fed with 15% corn oil (15%kg-diet) containing a number of 18 : 2 (linoleic acid) or 15% beef-tallow (15%/kg-diet) containing saturated fatty acids for 3 weeks, and were followed by feeding the petroleum ether extract (25 mg/kg-diet) for 3 weeks. The other group of rats (control group) were fed with 15% corn oil or 15% beef-tallow for 6 weeks. The platelet aggregation induced by thrombin and collagen was significantly inhibited and the thrombin time was prolonged in the 15% corn oil plus petroleum ether extract administrated group than in the 15% corn oil administrated group. And the same results were shown in the 15% beef-tallow plus petroleum ether extract administrated group. These results suggest that the petroleum ether extract from Korean red ginseng may have the beneficial effects on the inhibition of the platelet aggregation and the inhibition of blood coagulation induced by dietary fats.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제16권11호
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• pp.1071-1075
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• 2010

무선 센서 네트워크에 활용되는 센서 노드는 제한된 전력, 메모리 동의 한정된 자원을 지니기 때문에, 제한된 에너지를 효율적으로 관리하기 위한 데이터 집계 기법의 연구가 활발히 진행되어 왔다. 한편, 센서 네트워크는 무선통신을 수행하기 때문에 공격자에게 쉽게 데이터 노출될 수 있다. 따라서, 센서 네트워크에서 데이터 집계를 위한 데이터 보호 기법에 관한 연구가 필수적이다. 그러나, 기존 데이터 집계를 위한 데이터 보호 기법은 네트워크 구성 및 데이터 집계 처리 시, 다수의 연산과 데이터 전송이 발생한다. 이러한 문제점을 해결하기 위하여, 본 논문에서는 데이터 집계를 위한 힐버트 커브(hilbert curve) 기반 데이터 보호 기법을 제안한다. 제안하는 기법은 트리 기반의 라우팅을 구성하여 이웃노드와의 통신을 최소화한다. 또한 seed에 기반한 힐버트 커브 기법을 통해 데이터를 암호화함으로써, 센서 노드간의 통신 시 공격자로부터 데이터를 보호할 수 있다. 마지막으로, 제안하는 기법이 메시지 전송량 및 센서노드 평균 수명 측면에서 기존 연구보다 우수함을 보인다.

• 대한수의학회지
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• 제63권1호
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• pp.3.1-3.9
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• 2023

The efficiency of somatic cell nuclear transfer (NT) in pigs is low and requires enhancement. We identified the most efficient method for zona pellucida (ZP) removal and blastomere aggregation in pigs and investigated whether the aggregation of NT and parthenogenetic activation (PA) of blastomeres could reduce embryonic apoptosis and improve the quality of NT-derived embryos by investigating. Embryonic developmental competence after ZP removal using acid Tyrode's solution or protease (pronase E). The embryonic developmental potential of NT-derived blastomeres was also investigated using well-of-the-well or phytohemagglutinin-L. We analyzed apoptosis in aggregate-derived blastocysts. The aggregation rate of protease-treated embryos was lower than that of Tyrode's solution-treated embryos (69.2% vs. 88.3%). No significant difference was observed between phytohemagglutinin-L and well-of-the-well (35.7%-38.5%). However, 2P1N showed a higher number of blastocysts compared to 3N (73.8% vs. 24.3%) and an increased blastocyst diameter compared to the control and 1P2N (274 ㎛ vs. 230-234 ㎛). In blastomeres aggregated using phytohemagglutinin-L, the apoptotic cell ratio was significantly higher in 1P2N and 3N than in 3P (5.91%-6.46% vs. 2.94%, respectively). Our results indicate that aggregation of one NT embryo with two PA embryos improved the rate of blastocysts with increased blastocyst diameter.

• 대한기계학회논문집B
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• 제27권2호
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• pp.173-180
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• 2003

Effects of the electric conductivity of particles were studied for the aggregation process of charged particles with a Brownian dynamic simulation in the free molecular regime. A periodic boundary condition was used for the calculation of the aggregation process in each cell with 500 primary particles of 16 nm in diameter. We considered two extreme cases, a perfect conductor and a perfect nonconductor. The electrostatic force on a particle in the simulation cell was considered as a sum of electrostatic forces from other particles in the original cell and its replicate cells. We assumed that aggregates were only charged with pre-charged primary particles. The morphological shape of aggregates was described in terms of the fractal dimension. The fractal dimension for the uncharged aggregate was D$_{f}$= 1.761. However, the fractal dimension decreased from 1.694 to 1.360 for the case of the perfect conductor, and from 1.610 to 1.476 for the case of the perfect nonconductor, with the increase of the average number of charges on the primary particle from 0.2 to 0.3. These values were smaller than that of the centered charge case.e.

• 품질경영학회지
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• 제41권4호
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• pp.709-724
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• 2013

Purpose: The purpose of this study is to examine five evaluation models constructed by different normalization and aggregation methods in terms of the volatility of rankings and rank reversals. We also explore how the volatility of rankings of the five models changes and how often the rank reversals occur when the outliers are removed. Methods: We used data published in the Complete University Guide 2014. Two universities with missing values were excluded from the data. The university rankings were derived by using the five models, and then each model's volatility of rankings was measured. The box-plot was used to detect outliers. Results: Model 1 has the lowest volatility among the five models whether or not the outliers are included. Model 5 has the lowest number of rank reversals. Model 3, which has been used by many institutions, appears to be in the middle among the five in terms of the volatility and the rank reversals. Conclusion: The university rankings vary from one evaluation model to another depending on what normalization and aggregation methods are used. No single model exhibits clear superiority over others in both the volatility and the rank reversal. The findings of this study are expected to provide a stepping stone toward a superior model which is both reliable and robust.

• 대한의생명과학회지
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• 제29권4호
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• pp.242-248
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• 2023

Platelets are activated at the sites of vascular injury by a number of molecules, including adenosine diphosphate, collagen and thrombin. The full platelet aggregation is absolutely essential for the normal hemostasis. Glycyrrhiza glabra is a well-known medicinal herb that grows in various parts of the world and is known to have various effects such as antioxidant, anti-inflammatory, anti-atherogenic, anti-osteoporotic and skin-whitening. However, the platelet inhibitory effect of Glycyrrhiza glabra extract (GGE) has not been identified. In this study, we investigated if GGE inhibited platelet aggregation. We observed that GGE inhibited collagen-induced platelet aggregation, Ca²⁺ mobilization, and thromboxane A2 generation. In addition, GGE suppressed phosphorylation of phosphatidylinositol-3 kinase (PI3K), Akt and elevated phosphorylation of inositol 1,4,5-trisphosphate receptor (IP3R), vasodilator stimulated phosphoprotein (VASP). Taken together, GGE showed strong antiplatelet effects and may be used to block platelet-mediated cardiovascular diseases.

• 한국고분자학회:학술대회논문집
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• 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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• pp.344-344
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• 2006

Poly(n-hexyl-(S)-3-methylpentylsilane) aggregates confined in microcapsules to keep the aggregation number and ranging in average polymer mass in a microcapsule from $2{\Box}10^{-16}\;to\;2{\Box}10^{-14}g$. were studied by circular dichroism measurements in ethanol (a non solvent) and tetrahydrofuran (an associative solvent at low temperature) at varioustemperatures. The size of each aggregate did not affect the optical activity because the circular dichroism was proportional to the aggregation number at the same condition. Moreover, the circular dichroism appreciably reflected the prepared method, i.e. temperature and solvent.

• Journal of applied mathematics & informatics
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• 제41권5호
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• pp.973-988
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• 2023

In real-life scenarios, we may have to deal with real numbers or numbers in intervals or a combination of both to solve multi-criteria decision-making (MCDM) problems. Also, we may come across a situation where we must combine this interval and actual number membership values into a single real number. The most significant factor in combining these membership values into a single value is by using aggregation operators or scoring algorithms. To overcome such a situation, we suggest the cubic hypersoft set (CHSS) concept as a workaround. Ultimately, this makes it simple for the decision-maker to obtain information without misconceptions. The primary aim of this study is to establish some operational laws for the cubic hypersoft set, present the fundamental properties of aggregation operators and propose an algorithm by using the technique of order of preference by similarity to the ideal solution (TOPSIS) technique based on correlation coefficients to analyze the stress-coping skills of workers.

• Asian-Australasian Journal of Animal Sciences
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• 제28권11호
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• pp.1565-1572
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• 2015

Porcine embryonic stem cells (pESCs) have become an advantageous experimental tool for developing therapeutic applications and producing transgenic animals. However, despite numerous reports of putative pESC lines, deriving validated pESC lines from embryos produced in vitro remains difficult. Here, we report that embryo aggregation was useful for deriving pESCs from in vitro-produced embryos. Blastocysts derived from embryo aggregation formed a larger number of colonies and maintained cell culture stability. Our derived cell lines demonstrated expression of pluripotent markers (alkaline phosphatase, Oct4, Sox2, and Nanog), an ability to form embryoid bodies, and the capacity to differentiate into the three germ layers. A cytogenetic analysis of these cells revealed that all lines derived from aggregated blastocysts had normal female and male karyotypes. These results demonstrate that embryo aggregation could be a useful technique to improve the efficiency of deriving ESCs from in vitro-fertilized pig embryos, studying early development, and deriving pluripotent ESCs in vitro in other mammals.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제15권12호
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• pp.933-937
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• 2009

본 논문에서는 IEEE 802.15.4 저속 무선개인통신망(LR-WPAN)을 기반으로 센서노드간의 흡간지연을 분석하고 이를 바탕으로 에너지 효율적이고 정확한 데이터 병합을 위한 동적 타임아웃 스케줄링을 제안한다. 제안기법은 흡간지연의 특성을 이용하여 애플리케이션이 요구하는 데이터 정확도를 만족하는 타임아웃을 무선 채널의 특성과 채널을 공유하는 노드의 수를 고려하여 결정한다. 제안 기법에서의 타임아웃은 기존의 데이터 병합 기법에서 타임아웃으로 사용했던 흡간지연의 최대값보다 훨씬 작으므로 센서노드의 메시지 대기로 인한 에너지 소모를 상당부분 줄일 수 있다. 또한, 응용애플리케이션이 요구하는 패킷의 수신률을 보장함으로써 데이터 병합의 정확도 유지할 수 있다. 시뮬레이션 결과, 동적 타임아웃 스케줄링 기법은 기존 흡간지연의 최대값을 타임아웃으로 사용하는 것 보다 에너지소모 측면에서 30%이상의 성능향상을 보였고 데이터 정확도의 성능저하는 거의 없었다.