• Journal of Oral Medicine and Pain
• /
• v.41 no.1
• /
• pp.21-25
• /
• 2016

Purpose: Burning mouth syndrome (BMS) is a chronic pain condition involving the oral and perioral regions, often characterized by a burning sensation and pain in elderly patients. In this study, we investigated the effectiveness of pharmacological agents for the treatment of BMS patients through a retrospective chart review. Methods: We enrolled 61 BMS subjects (57 females, 4 males; $66.4{\pm}10.9$ years of age) from among consecutive patients treated pharmacologically from January 2014 to June 2015 at Chonnam National University Dental Hospital. Patients with secondary BMS associated with local factors were excluded. The treatment period, number of pharmacological agents tried, and effectiveness of the drugs administered to each subject were analyzed. Results: The mean treatment period for the management of BMS was 2.5 months. More than three agents were tried to control BMS symptoms in 17 subjects (27.9%); two agents were used in 10 subjects (16.4%), and a single agent in 24 subjects (39.3%). Clonazepam was prescribed most frequently and was effective at relieving symptoms in 30 of 39 subjects (76.9%). Paroxetine was moderately effective, relieving symptoms in 7 of 17 subjects (41.2%). Some of the subjects benefited from tricyclic antidepressants, gabapentin, and lipoic acid. A topical local anesthetic used to supplement other systemic agents had ameliorating effects in four of six subjects. Conclusions: Within the study limitations, clonazepam was the most effective drug and antidepressants were efficacious in some subjects for relieving the symptoms of BMS. These pharmacological agents could be considered as first-line drugs for the management of BMS.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.36 no.1
• /
• pp.47-55
• /
• 2010

UV-screening agents have some adverse effects that raise consumers' concern. The organic agents often cause irritation and may penetrate into human body while the inorganic agents raise aesthetic issues because they often turn opaque. Organic agents with high molecular weights and nano-sized inorganic agents have been developed respectively to minimize transdermal intrusion into human body and suppress turning opaque. Recently, we reported preparation of powdery UV-screening agents made of polysilsesquioxane, an organic-inorganic hybrid material. Powders would not penetrate into epidermis and organic-inorganic hybrid nature would suppress the opaqueness problem. In this study, we continued our research on this powdery polysilsesquioxane UV-screening agent, SESQUV, regarding its chemical composition, its synergic UV-screening effects when mixed with other organic agents, and its applicability in practical formulation. Results showed SESQUV was promising UV-screening agents useful in sunscreen formulation.

• Proceedings of the Korean Institute of Intelligent Systems Conference
• /
• 2008.04a
• /
• pp.266-267
• /
• 2008

We argue that agents may benefit from strategic ignorance in argumentation-based negotiation (ABN). We assume our agents are selfish, myopic, and residing in open systems. Some analytical results that can be used for designing agent reasoning on strategic ignorance are provided.

• Archives of Pharmacal Research
• /
• v.20 no.2
• /
• pp.197-199
• /
• 1997

In conclusion, benzotriazole analogs prepared in this research showed strong possibility to be photochemically activated DNA cleaving agents. Electrophilic groups such as haloacetoxy groups on the alkyl chain of benzotriazole analogs promote the DNA cleaving ability. Synthesis of 1-(2-Naphthoyl) Benzotriazoles.

• Proceedings of the Korea Inteligent Information System Society Conference
• /
• 2004.11a
• /
• pp.119-136
• /
• 2004

ㆍuT ontologies can enable context awareness to represent more rich information. ㆍOntologies enable uT agents to reason about dynamic contexts. ㆍMulti agents can use ontologies to communicate between agents.

• Journal of The Korean Association of Information Education
• /
• v.3 no.2
• /
• pp.41-53
• /
• 2000

The purpose of the paper is communication between multi-agents for student's learning at web based collaborative learning. First, this study investigated the whole contents and characteristics of an agent system and discussed KQML, communication language between multi-agents. Also, we suggested architecture of an agent based system for collaborative learning and interaction method between agents using KQML. We design어 and implemented collaborative learning system using Java programming language, and we also demonstrate the efficiency of collaborative learning system by communication between multi-agents through experiments.

• Journal of The Korean Society of Clinical Toxicology
• /
• v.1 no.1
• /
• pp.40-42
• /
• 2003

Korean people use a lot of herbal agents for medical purposes, such as curing diseases, improving health state, but some of the herbal agents have toxic side effects. In terms of toxicology, herbal agents classified into 3 categories generally nontoxic, potentially toxic and toxic. But, there are few studies about the mechanisms and clinical features of intoxication of herbal agents. So detoxification or initial treatment of these agents is very difficult to clinicians in hospital. Authors experienced an uncommon case of intoxication after Arisaematis Rhizoma Ingestion. We report this case with review of Arisaematis Rhizoma.

• Microbiology and Biotechnology Letters
• /
• v.25 no.3
• /
• pp.335-337
• /
• 1997

In this study, we show a convenient MTT assay for detect the susceptibility of yeast-like form of Trichosporon beigelii against antifungal agents. This assay was developed based on mitocondrial respiration by determining reduction of 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) to formazan. Cells of T beigelii are seeded into 96-well microtiter plates, and antifungal agents, amphotericin B, magainin and CA-ME hybrid peptide were added with various concentrations. After 24 hr incubation, MTT was added, then incubations were continued for 4 hr. Formazan formation was quantified photometrically after extraction of the formazan with acid sodium dodesyl sulfate (SDS). From this assay, we could obtained MICs of antifungal agents against T. beigelii. The presented method can easily be used as an effective methods to assess the antiftingal action of various agents on yeasts with minimal amounts of antifungal agents.

• Journal of the Korean Magnetic Resonance Society
• /
• v.14 no.1
• /
• pp.9-17
• /
• 2010

The water proton relaxation rates increase linearly with concentrations of contrast agents, and could be expressed as a function of the concentrations. In this paper, we have investigated MR properties of two different contrast agents, $GdCl_3$ and $CoCl_2$. Relaxivity coefficients were calculated from individual contrast agent solutions, and used for predicting relaxation rates at mixtures of two contrast agents. From the experimental results, we have discussed the feasibility of constructing water solutions with the desired relaxation times using specific mixtures of contrast agents.

• Journal of Agricultural Extension & Community Development
• /
• v.6 no.2
• /
• pp.85-103
• /
• 1999

The objectives of the study were to review the agricultural environment education program for nasal change agents, to find out their recognition on agricultural environment and to get sorn implications for better educational program of rural environment. The data were gathered from 177 rural change agents in 11 agricultural technology centers in Kyongi-Do province by mailing survey with questionnaire. The major findings of the study were ; (1) Agricultural environment education for rural extention workers initiated in 1996. From 1999 diversified programs were served for them. (2) Rural change agents perceived that water contamination and degradation of life environment were the most serious problem. (3) Educational program on organic farming should be prepared for farmers and rural changes agents. (4) Concrete educational programs for adequate use of agricultural chemicals should be prepared for farmers. (5) Educational program on agricultural environment policies should be reorganized in terms of the level of target group. (6) RDA should prepare synthetical education program for the conservation of rural eco-system.