• Fashion & Textile Research Journal
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• v.14 no.1
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• pp.48-55
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• 2012

The purpose of this study was to review the results of previous researches related to cognitive age and to verify variables related to cognitive age. Using the key words of cognitive age, subjective age, self-perceived age and age difference from major academic databases in Korea (KISS), the related research articles were collected and analyzed. The results of this study were as follows: First, educational level and marital status were related to cognitive age but its relationship to the other demographic variables were inconsistent. Second, self-esteem and life satisfaction were associated with cognitive age. Third, consumer behavior such as information-seeking behavior, impulsive buying orientation and brand sensitivity and clothing behavior such as apparel shopping orientation and fashion leadership were related to cognitive age.

• Korean Journal of Veterinary Research
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• v.35 no.1
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• pp.29-37
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• 1995

This study was carried out to investigate the morphological changes of the oxytocin secreting neurons in age-related rat hypothalamus by means of immunohistochemistry. The experimental group was 20 aged female rats (Sprague-Dawley, 25~30 months), and the control group was 10 adult female rats (10 months). All animals were perfused transcardially with 4% paraformaldehyde-lysine-periocdate(PLP), and serial transverse brain sections($30{\mu}m$) were prepared by means of cryotome, and were stained with rabbit anti-oxytocin antisera immunohistochemically, using the free floating method and avidin-viotin peroxidase complex. The results were as followings. 1. The immunostained oxytocin secreting neurons were located at the paraventricular nucleus and supraoptic nucleus of age-related rat hypothalamus chiefly. 2. The numbers of oxytocin secreting neurons decreased at the paraventricular nucleus and supraoptic nucleus of age-related rat hypothalamus(p<0.01) 3. The oxytocin secreting neurons of age-related rat hypothalamus immunostained less than those of the adult rat hypothalamus, and the paraventricular nucleus immunostained greater than supraoptic nucleus in age-related rat. 4. The numbers and expansion of dendrite and axonal varicosities decreased in the age-related rat hypothalamus greatly.

• Archives of Craniofacial Surgery
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• v.16 no.2
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• pp.58-62
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• 2015

Background: Age-related changes have been studied for lower and middle facial bones. Although the forehead comprises one-third of the facial area, no studies have investigated age-related changes in the upper part of the face or forehead. The purpose of this study was to use three-dimensional computed tomography (3D CT) to investigate age-related changes in the frontal bone. Methods: A retrospective review was performed for patients who underwent 3D CT scan of facial bones. Patients were divided by gender and age (20 to 40 years, 41 to 60 years, and above 60 years). The frontal bone curvature was evaluated by the length of frontal bone and by two frontal bone angles in relation to the Frankfurt horizon. Results: In both genders, aging was associated with increasing lower slope length. In elderly men (>60 years), the upper slope angle was significantly higher when compared to younger male subjects. Women demonstrated similar age-related changes, but the differences were only statistically significant for the middle and older age groups. Conclusion: This study demonstrates quantifiable age-related changes in the frontal bone. These findings contribute to the understanding of age-related changes of the facial soft tissues. The mean measurements in each age group can be used as a reference when planning forehead reconstruction.

• Korean Journal of Adult Nursing
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• v.24 no.4
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• pp.339-347
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• 2012

Purpose: The purpose of this study was to identify the influencing factors on health related quality of life in middle age. Methods: Data were as collected by self-reported questionnaires from 303 middle age adults. Data analysis was done using SPSS/WIN 17.0 program for descriptive statistics, Pearson correlation coefficients and stepwise multiple regression. Results: The average score of health related quality of life was $79.50{\pm}0.40$. Health related quality of life was statistically significant differences according to gender, education, economic status and disease. The health related quality of life was significantly correlated with fatigue, depression, stress, social support, somatic attribution, psychological attribution, normalizing attribution and type D personality. The major factors that affect health related quality of life in middle age were stress, fatigue, type D personality and normalizing attribution, which explained 51.3% of health related quality of life. Conclusion: The findings can provide the basis for the development of nursing interventions to improve health related quality of life. Furthermore, more studies are needed to explore variables that influence on the health related quality of life in middle age.

• IMMUNE NETWORK
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• v.23 no.5
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• pp.36.1-36.16
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• 2023

Thymic epithelial cells (TECs) play a critical role in thymic development and thymopoiesis. As individuals age, TECs undergo various changes that impact their functions, leading to a reduction in cell numbers and impaired thymic selection. These age-related alterations have been observed in both mice and humans. However, the precise mechanisms underlying age-related TEC dysfunction remain unclear. Furthermore, there is a lack of a comprehensive study that connects mouse and human biological processes in this area. To address this gap, we conducted an extensive transcriptome analysis of young and old TECs in mice, complemented by further analysis of publicly available human TEC single-cell RNA sequencing data. Our analysis revealed alterations in both known and unknown pathways that potentially contribute to age-related TEC dysfunction. Specifically, we observed downregulation of pathways related to cell proliferation, T cell development, metabolism, and cytokine signaling in old age TECs. Conversely, TGF-β, BMP, and Wnt signaling pathways were upregulated, which have been known to be associated with age-related TEC dysfunctions or newly discovered in this study. Importantly, we found that these age-related changes in mouse TECs were consistently present in human TECs as well. This cross-species validation further strengthens the significance of our findings. In conclusion, our comprehensive analysis provides valuable insight into the biological and immunological characteristics of aged TECs in both mice and humans. These findings contribute to a better understanding of thymic involution and age-induced immune dysfunction.

• Journal of Korean Biological Nursing Science
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• v.24 no.1
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• pp.26-35
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• 2022

Purpose: The purpose of this study was to investigate the influencing factors on health-related quality of life according to body mass index (BMI) in middle age people. Methods: Using the 2017 Korea Health Panel Data, a total of 4,711 subjects age 40-64 were selected and classified into four groups based on BMI levels (underweight, normal weight, overweight, obese). Influencing factors according to BMI in middle age people was analyzed using multiple regression. Results: Activity limited was the most influential factor for health-related quality of life in middle age people. Walking and stress were factors influencing health-related quality of life in all weight groups. In the overweight and obese group, suicidal impulse was a significant influencing factor on health-related quality of life. Conclusion: To improve the health-related quality of life of middle age people, effective walking and stress management for maintaining and managing health, as well as managing suicide risk in the overweight group and obese group are required.

• Journal of Biomedical Engineering Research
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• v.21 no.3 s.61
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• pp.285-293
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• 2000

Age-related changes in the geometry of human lumbar spine would lead to changes of its mechanical behaviors. To investigate the effects of the geometric changes, no age-related changes in the material/mechanical properties were considered. Using the finite element method. two age-related models of lumbar spine segments (L3-L4) were constructed. The annulus of the models was modeled as laminate composite elements with 16 layers and 6 materials. The spinal stiffness and facet reaction of the lumbar spine increased with the age-related geometric changes in various combined loadings. Fiber and transverse tensile strains of the inner annulus. cancellous bone stress and end-plate stress decreased with the age-related geometric changes whereas fiber/layer compressive strains of the annulus. facet reaction. ligament reaction and end-plate rigidity increased. Consequently, it appears that in the normal age-related deterioration of discs, the age-related geometric change contributes to the increase of spinal stiffness (the decrease in range of the motion segment), preventing an excessive deformation of the disc.

• Journal of Family Resource Management and Policy Review
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• v.9 no.1
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• pp.113-130
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• 2005

The purpose of this study was to show the expected age of retirement of the couple, husband and wife, individually, the difference between the expected age of retirement of the husband and that of the wife, and to analyze contributing variables. The sample in this study numbered 517, of which 229 were husbands and 288 were wives. The independent variables were divided into three factors including personal, financial, and work related variables. The results of this study were as follows. Among two earner households, both husbands and wives expected the husband's age of retirement to be higher than of the wife. The difference between the husband's expected age of retirement and the wife's expected age of retirement was five years, on average. For the husband, personal, financial, and work related variables had effects on his expected age of retirement. However, for the wife it was only the perception of future work life and expected age of retirement of the partner which had very significant effects statistically. The variables affecting the difference between the expected age of retirement of the husband and that of the wife included the personal variables as well as interaction of the couple related variables. The results showed that first of all, the planning of retirement among two earner households needs to be focused on the couple rather than on the individual.

• Journal of Korean society of Dental Hygiene
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• v.17 no.5
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• pp.841-851
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• 2017

Objectives: The purpose of the study is to investigate the relationship between life satisfaction, awareness of their old age, and preparation for their old age among dental hygienists. Methods: A self-reported questionnaire was completed by 258 dental hygienists in Seoul, Gyeonggido, Incheon and Gangwondo from September 30 to October 30, 2016. The questionnaire consisted of general characteristics (10 items), life satisfaction (10 items), awareness of old age (13 items) and preparation for old age (23 items). Respondents were asked to choose on the Likert 5-point scale. Results:Significant relationships were found between life satisfaction, awareness about old age and preparation for old age among dental hygienists (p<0.01): physical preparation for old age was related to life satisfaction; economic preparation for old age was related to life satisfaction, awareness for old age, 10 or more years of experience as dental hygienist and having offspring (two or more children). Psycho-emotional preparation for old age was related to life satisfaction and awareness for old age. Conclusions:It is necessary to find ways to increase life satisfaction and awareness of old age for their old age among dental hygienists.

• Women's Health Nursing
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• v.30 no.1
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• pp.56-66
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• 2024

Purpose: This study explored the factors influencing the health-related life satisfaction of people with disabilities who engaged in physical activity, by age and gender. Methods: A secondary analysis was conducted of the 2020 Third Disability and Life Dynamics Panel (2021). The participants were 2,796 people who performed regular physical activity at least once a week. The variables selected were disability-related factors (degree of disability, multiple disabilities, and type of disability), sociodemographic factors (age, gender, living alone, and mean monthly family income), and health-related factors (amount of physical activity, self-esteem, depression, chronic disease, subjective health, and health-related life satisfaction). Descriptive statistics, the chi-square test, the t-test, two-way analysis of variance, and multiple regression analysis were conducted. Results: In total, 58.0% of participants were male, and 42.0% were female. For age groups, 14.4% were children/adolescents (0-19 years), 42.6% were adults (20-59 years), and 43.0% were seniors (≥60 years). The mean score for health-related life satisfaction was 5.0±2.15 out of 10. Adults and seniors whose level of physical activity met or exceeded recommendations had higher subjective health. Moreover, men had better subjective health than women in seniors. Health-related life satisfaction was higher among those who had higher self-esteem, were not depressed, did not have chronic diseases, and had better subjective health. Conclusion: Gender significantly influenced health-related life satisfaction in children/ adolescents and seniors. Disability-related factors were significant in adults, and health-related factors were significant in all age groups. Therefore, these factors should be considered when designing interventions to promote subjective health and health-related life satisfaction of people with disabilities.