• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1999년도 학회창립 10주년 기념 1999년도 가을 학술발표회 논문집
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• pp.285-288
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• 1999

Creep is a major parameter to represent long-term behavior of concrete structures concerning serviceability and durability. The effect of creep is recently taking account into crack resistance analysis of early-age concrete concerning durability evaluation. Since existing creep prediction models were proposed to predict creep for hardened concrete, most of them cannot consider effectively the information on microstructure formation and hydration developed in the early-age concrete. In this study, creep tests for early-age concrete made of the type I cement and the type V cement are carried out respectively and creep prediction models are evaluated for the prediction of creep behavior in early-age concrete. A creep prediction model is modified for the prediction of creep in early-age concrete and also verified by comparing prediction results with results of creep tests on early-age concrete.

• BMB Reports
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• 제50권11호
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• pp.546-553
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• 2017

Aging is a natural and gradual process in human life. It is influenced by heredity, environment, lifestyle, and disease. DNA methylation varies with age, and the ability to predict the age of donor using DNA from evidence materials at a crime scene is of considerable value in forensic investigations. Recently, many studies have reported age prediction models based on DNA methylation from various tissues and body fluids. Those models seem to be very promising because of their high prediction accuracies. In this review, the changes of age-associated DNA methylation and the age prediction models for various tissues and body fluids were examined, and then the applicability of the DNA methylation-based age prediction method to the forensic investigations was discussed. This will improve the understandings about DNA methylation markers and their potential to be used as biomarkers in the forensic field, as well as the clinical field.

• 전기전자학회논문지
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• 제26권3호
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• pp.494-499
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• 2022

본 논문에서는 인간의 피부섬유모세포(Human dermal fibroblasts)로부터 확보한 전사체 정보를 활용하여 나이를 예측하는 방법을 소개한다. 제안 방법에서는 훈련을 통해 확보한 분류기 및 회귀 모델을 이용하여 샘플이 속한 적합한 연령 그룹을 선택한 후, 선택된 연령 그룹에 속하는 훈련 데이터의 관측값을 활용하여 구체적인 연령을 예측한다. 연령을 예측하려는 샘플이 입력되면 복수 개의 판별 규칙이 순서대로 실행되는데, 개별 판별 규칙에서는 분류기와 회귀 모델을 동시에 실행하여 해당 판별 규칙에 대한 선택조건이 만족되는지 여부를 확인한다. 선택 조건이 만족될 경우 판별 규칙의 타겟 연령 그룹에 속하는 데이터를 이용하여 훈련된 회귀 모델로 연령을 예측하며, 선택 조건이 만족되지 않으면 후속 판별 규칙을 실행한다. 공개 데이터에 대하여 실험한 결과 기존 연구에서 달성한 7.7년의 평균 예측 오차보다 우수한 5.7년이라는 평균 예측 오차를 달성함을 확인하였다.

• 한국콘텐츠학회논문지
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• 제15권6호
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• pp.276-282
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• 2015

태아의 소뇌는 임신주수에 따라 성장하며 소뇌횡직경 길이의 측정은 임상에서 태아성장 예측의 중요한 지표로 활용하고 있다. 본 연구에서는 임신 20~37주 사이의 산모를 임신 주수별 각 20명씩 총 340명을 대상으로 3차원초음파 탐촉자를 이용하여 태아의 태령 및 태아의 소뇌 양쪽 외단을 측정해 기초자료를 획득하였다. 결과적으로 임신 주수에 따른 태아 소뇌횡직경의 성장을 회귀곡선으로 표시하였고 선형회귀방정식에서 결정계수를 얻었다. 3차원초음파를 이용한 임신주수에 따른 소뇌횡직경 측정방법은 통계적으로 유의(p<0.001)하였으며, 태령을 예측함에 있어 유용하다는 것을 알 수 있었다. 그러므로 임신주수에 따라 증가하는 소뇌횡직경의 측정은 정확한 임신주수의 산정이 가능 할 것이며 임상에서 현재 이용되고 있는 태령측정 방법의 대체 또는 개선방법이라 사료된다. 태아의 성장에 따라 측정하는 소뇌형직경은 임신주수에 따른 태아 성장의 평가가 가능하며, 태아의 머리 모양에 관계없이 성장장애가 있는 경우에도 임신주수의 예측이 가능하다. 따라서 본 연구를 기초자료로 하여 지속적인 연구가 시행된다면 3차원초음파를 이용한 소뇌횡 직경의 측정은 정확한 임신주수 예측에 유용할 것으로 사료된다.

• Asian-Australasian Journal of Animal Sciences
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• 제24권5호
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• pp.603-609
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• 2011

Telomeres are special structures at the ends of eukaryotic chromosomes. Vertebrate telomeres consist of tandem repeats of conserved TTAGGG sequence and associated proteins. Birds are interesting models for molecular studies on aging and cellular senescence because of their slow aging rates and longer life spans for their body size. In this longitudinal study, we explored the possibility of using telomeres as an age-marker to predict age in Single Comb White Leghorn layer chickens. We quantified the relative amount of telomeric DNA in isolated peripheral blood lymphocytes by the Quantitative Fluorescence in situ Hybridization technique on interphase nuclei (IQ FISH) using telomere-specific DNA probes. We found that the amount of telomeric DNA (ATD) reduced significantly with an increase in chronological age of the chicken. Especially, the telomere shortening rates are greatly increased in growing individuals compared to laying and old-aged individuals. Therefore, using the ATD values obtained by IQ FISH we established the possibility of age prediction in chickens based on the telomere theory of aging. By regression analysis of the ATD values at each age interval, we formulated an equation to predict the age of chickens. In conclusion, the telomeric DNA values by IQ FISH analyses can be used as an effective age-marker in predicting the chronological age of chickens. The study has implications in the breeding and population genetics of poultry, especially the reproductive potential.

• 한국건축시공학회지
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• 제2권4호
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• pp.177-182
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• 2002

The purpose of this study is to develope the strength prediction model by Maturity Method. A maturity function is a mathematical expression to account for the combined effects of time and temperature on the strength development of a cementious mixture. The method of equivalent ages is to use Arrhenius equation which indicates the influence of curing temperature on the initial hydration ratio of cement. For the experimental factors of this study, we selected the concrete mixing of W/C ratio 45, 50, 55 and 60% and curing temperature 5, 10, 20 and $30^{\circ}C$. And we compare and evaluate with logistic model that is existing strength prediction model, because we have to verify adaption possibility of new strength prediction model which is proposed by maturity method. As the results, it is found that investigation of the activation energy that are used to calculate equivalent age is necessary, and new strength prediction model was proved to be more accurate in the strength prediction than logistic model in the early age. Moreover, the use of new model was more reasonable because it has low SSE and high decisive factor.

• Journal of Animal Science and Technology
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• 제45권2호
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• pp.327-334
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• 2003

본 시험은 초음파를 이용하여 한우의 도체형질을 조기에 예측하기 위하여 거세한우 66두를 대상으로 18, 21 및 24개월령에 도체형질을 측정하고, 중회귀 분석 및 의사결정나무 분석을 이용하여 24개월령 출하시 도체형질을 예측하였다. 그 결과를 요약하면 다음과 같다. 도체육량등급에 따라 군을 분류하고 성장에 따른 도체형질의 변화를 관찰한 결과, 등지방 두께는 전기간에 걸쳐 각 도체육량등급간에 유의적(p<0.05)인 차이를 보이며 A, B, C등급 순으로 얇게 나타났다. 중회귀 분석에 의한 도체육량등급의 예측율은 18, 21 및 24개월령에서 각각 78.8%, 86.4% 및 90.9%를 나타냈으며, 의사결정나무 분석에 의한 도체육량등급 예측율은 각 개월령에 따라 78.8%, 89.4% 및 89.4%를 나타냈다.

• 콘크리트학회논문집
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• 제12권4호
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• pp.69-78
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• 2000

Creep of concrete is the most dominating factor affecting time-dependent deformations of concrete structures. Especially, creep deformation for design and construction in prestressed concrete structures should be predicted accurately because of its close relation with the loss in prestree of prestressed concrete structures. Existing creep-prediction models for special applications contain several impractical factors such as the lack ok accuracy, the requirement of long-term test and the lack of versatility for change in material properties, ets., which should be improved. In order to improve those drawbacks, a methodology to modify the creep-prediction equation specified in current Korean concrete structures design standard (KCI-99), which underestimates creep of concrete and does not consider change of condition in mixture design, is proposed. In this study, short-term creep tests were carried out for early-age concrete within 28 days after loading and their test results on influencing factors in the equation are analysed. Then, the prediction equation was modified by using the early-age creep test results. The modified prediction equation was verified by comparing their results with results obtained from long-term creep test.

• 농업과학연구
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• 제47권4호
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• pp.769-782
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• 2020

Interest in fruit and vegetables has increased due to changes in consumer consumption patterns, socioeconomic status, and family structure. This study determined the factors influencing the demand for fruit and vegetables (strawberries, paprika, tomatoes and cherry tomatoes) using a panel of Rural Development Administration household-level purchases from 2010 to 2018 and compared the ability to the prediction performance. An artificial neural network model was constructed, linking household characteristics with final food expenditure. Comparing the analysis results of the artificial neural network with the results of the panel model showed that the artificial neural network accurately predicted the pattern of the consumer panel data rather than the fixed effect model. In addition, the prediction for strawberries was found to be heavily affected by the number of families, retail places and income, while the prediction for paprika was largely affected by income, age and retail conditions. In the case of the prediction for tomatoes, they were greatly affected by age, income and place of purchase, and the prediction for cherry tomatoes was found to be affected by age, number of families and retail conditions. Therefore, a more accurate analysis of the consumer consumption pattern was possible through the artificial neural network model, which could be used as basic data for decision making.

• The Korean Journal of Pain
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• 제33권2호
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• pp.153-165
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• 2020

Background: Well-validated risk prediction models help to identify individuals at high risk of diseases and suggest preventive measures. A recent systematic review reported lack of validated prediction models for low back pain (LBP). We aimed to develop prediction models to estimate the 8-year risk of developing LBP and its recurrence. Methods: A population based prospective cohort study using data from 435,968 participants in the National Health Insurance Service-National Sample Cohort enrolled from 2002 to 2010. We used Cox proportional hazards models. Results: During median follow-up period of 8.4 years, there were 143,396 (32.9%) first onset LBP cases. The prediction model of first onset consisted of age, sex, income grade, alcohol consumption, physical exercise, body mass index (BMI), total cholesterol, blood pressure, and medical history of diseases. The model of 5-year recurrence risk was comprised of age, sex, income grade, BMI, length of prescription, and medical history of diseases. The Harrell's C-statistic was 0.812 (95% confidence interval [CI], 0.804-0.820) and 0.916 (95% CI, 0.907-0.924) in validation cohorts of LBP onset and recurrence models, respectively. Age, disc degeneration, and sex conferred the highest risk points for onset, whereas age, spondylolisthesis, and disc degeneration conferred the highest risk for recurrence. Conclusions: LBP risk prediction models and simplified risk scores have been developed and validated using data from general medical practice. This study also offers an opportunity for external validation and updating of the models by incorporating other risk predictors in other settings, especially in this era of precision medicine.