The study was focused to evaluate the possibility for combination membrane of bacterial cellulose (BC) and graphene with high electrical properties. BC with natural polymer matrix was known to have strong physical strength. For the combination of graphene with BC, the surface of graphene was modified with oxygen plasma by changing strength and time of radio waves in room temperature. Water contact angle of modified graphene grew smaller from $130^{\circ}$ to $12^{\circ}$. XPS analysis showed that oxygen content after treatment increased from 2.99 to 10.98%. Damage degree of graphene was examined from $I_D/I_G$ ratio of Raman analysis. $I_D/I_G$ ratio of non-treated graphene (NTG) was 0.11, and 0.36 to 0.43 in plasma treated graphene (PTG), increasing structural defects of PTG. XRD analysis of PTG membrane with BC was $2{\theta}$ same to BC only, indicating chemically combined membrane. In FT-IR analysis, 1,000 to 1,300 $cm^{-1}$ (C=O) peak indicating oxygen radicals in PTG membrane had formed was larger than NTG membrane. The results suggest that BC as an alternation of plastic material for graphene combination has a possibility in some degree on the part like transparent conductive films.
Purpose: The way in which the resection margin distance for gastric cancer patients who undergo a gastric resection influences the recurrence rate, aspects of recurrence, and the prognosis according to the characteristic of the tumor is not known. We aim to find a standard for tailor-made treatment after selecting patients in this point of view who need a more sufficient resection margin. Materials and Methods: A retrospective study was done on 1,472 patients who underwent a gastrectomy due to gastric cancer at our hospital from 1992 to 2005. The median follow-up period was 37 months. Results: There were no significant differences in the recurrence rate, the aspects of recurrence, and the 5-year survival rate between early gastric cancer (EGC) patients with a resection margin distance of less than 2 cm compared with EGC patients with a resection margin distance of greater than 2 cm. However, significant differences in the survival rate were found in advanced gastric cancer (AGC) patients when the patients were classified into groups with resection margin distances less than or greater than 3 cm (P=0.02). Significant differences were noted especially in cases of diffuse histologic-type tumors located in the lower third of the stomach and in cases with Borrmann type-3 and -4 tumors. Conclusion: The distance between the tumor resection margin and the proximal gastric resection margin has no significant influence on the survival rate in EGC patients if the resection margin is negative. However, to improve a patient's survival rate, it is important to guarantee a resection margin of more than 3 cm in AGC patients, especially when the tumor is a diffuse histologic type located in the lower third of the stomach or a Borrmann type 3 and 4.
Kim, Gwon-Sik;Kim, Kap-Choong;Kim, Beom-Su;Kim, Tae-Hwan;Yook, Heong-Hwan;Oh, Sung-Tae;Kim, Byung-Sik
Journal of Gastric Cancer
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v.10
no.3
/
pp.111-117
/
2010
Purpose: The aim of this study was to determine the prognostic factors and the significance of metastatectomy for Krukenberg's tumors of gastric origin.Materials and Methods: Among the patient who underwent gastric surgery from 1992 through 2005, 90 female patients with Krukenberg's tumors of gastric origin were identified. We retrospectively reviewed the clinicopathologic characteristics, prognostic factors, and treatments for primary gastric cancer. We also investigated the prognostic risk factors for the onset of metachronous Krukenberg's tumors and the survival time of patients who underwent an operation for metachronous Krukenberg's tumors. Results: The presence of a synchronous Krukenberg's tumor (mean survival time=17.6 months, P<0.01), peritoneal seeding (14.5 months, P<0.01), and non-curative resection (15.1 months, P<0.01), were statistically significant prognostic factors for survival time in female patients with gastric cancer. The stage of primary gastric cancer (P=0.049) and lymph node metastasis (P=0.011) were statistically significant risk factors for recurrence time of a metachronous Krukenberg's tumor. In the metachronous Krukenberg's tumor group (n=53), the mean survival time of the metastatectomy group (n=46, 43.2 months, P=0.012) was longer than that in the chemotherapy or conservative treatment groups (n=7 and 24 months, respectively). Metastatectomy, presense or abscence of residual tumor and extent of residual tumor were significant prognostic factors for survival time in female patients with metachronous Krukenberg's tumor of gastric origin. Conclusions: A close observation and evaluation with ultrasound or computed tomography is necessary in female patients with advanced gastric cancer to detect a metachronous Krukenberg's tumor as soon as possible. The surgeon must operate more aggressively in patients with metachronous Krukenberg's tumors.
Process analysis with ASM3 (Activated Sludge Model3) was performed to offer basic data for the optimization of aerated biofilter (ABF) process design and operation. This study was focused on the simulation of the nitrification reaction in ABF which was a part of the advanced nutrient treatment process using bio-adsorption. The ABF process has been developed for the removal of suspended solids and nitrification reaction in sewage. A GPS-X (General Purpose Simualtor-X) was used for the sensitivity analysis and operation assessment. Sensitivity of ASM3 parameters on ABF was analysed and 4 major parameters ($Y_A$, $k_{sto}$, ${\mu}_A$, $K_{A,HN}$) were determined by dynamic simulation using 70 days data from pilot plant operation. The optimized values were 0.14 for $Y_A$, 3.5/d for $k_{sto}$, 2.7/d for ${\mu}_A$ and 1.1 mg/L for $K_{A,HN}$, respectively. Simulation with optimized parameter values were conducted and TN, $NH_4{^+}-N$ and $NO_3{^-}-N$ concentrations were estimated and compared with measured data at the range of 10 min to 4 hrs of hydraulic retention time (HRT). The simulated results showed that optimized parameter values could represent the characteristics of ABF process. Especially, the ABF showed relatively high nitrification rate (60%) under very short HRT of 10 min. As a consequence, the ABF was thought to be successfully used in the site which having high variation of influent loading rate.
Purpose : Schulte introduced immediate implant cases in 1970s, since then many patients have been treated by immediate implants. The aim of this study was to evaluate the cumulative survival rate of immediate implant and to analyze various factors associated with survival of immediate implant in a 8-year period retrospectively. Materials and methods : From May, 2000 to October, 2007, 77 implants were placed in 63 patients immediately after tooth extraction at Department of Periodontology, Yonsei University Hospital. The implant survival rate was analyzed using a life-table analysis. After delivery of prosthesis, along 1 year of observation period, all implants were evaluated clinically and radiographically. Results : Among 77 implants, 59 were placed in maxilla and 18 in mandible. The most common site of the implantation was Mx anterior (65%). The overall survival rate was 94.8% over a mean follow-up period of $44.2{\pm}21$ months and the 8-year cumulative survival rate was 94.6%. Failure occurred in 4 implants, all of which were due to early failures. None of the following factors were significantly associated with the survival of immediate implants: advanced surgical technique including bone graft and guided bone regeneration, the types of implants, causes of tooth loss, and types of prosthesis. Conclusion : On the basis of 8-year life time analysis, immediate implant placement can be considered a safe and predictable treatment mordality.
Journal of Korean Society for Atmospheric Environment
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v.24
no.1
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pp.72-82
/
2008
Benzene is a very harmful and toxic compound known as human carcinogen by all routes of exposure. Owing to the risky feature of benzene, several countries such as Japan, UK and EU have established the ambient air quality standard and protect from that risk of it. Korea also has designated it as one of the criteria air pollutants and established the concentration limit ($5\;{\mu}g/m^3$) in the air and is going to apply the standard from 2010. Benzene is emitted from various sources such as combustion plants, production processes, waste treatment facilities and also automobiles. Mobile source is known as one of the major emission sources of benzene. In this study, we estimated the domestic emissions of benzene from mobile source and compared the results with those of advanced countries. Mobile source was divided into 2 categories, Le., on-road source and non-road source. The total emissions of benzene from mobile source were estimated as 3,106 tons/yr and 1,612 tons/yr was emitted from on-road source and 1,494 tons/yr was from non-road source. Emission ratio of benzene from on-road source showed that 80.0% was from passenger cars, 10.1% was from taxis, 7.2% was from light-duty vehicles, 2.5% was from heavy-duty vehicles and 0.2% was from buses. In the case of non-road source, the distribution showed that 66.3% was from construction machineries, 14.5% was from locomotives, 11.7% was from ships, 7.1% was from agriculture equipments and 0.5% was from aircrafts. The cold-start emissions were estimated as 942 tons/yr and this value was almost 1.5 times greater than that for hot engine emissions (608 tons/yr). In addition, the fuel-based distribution was 65.9%, 31.1% and 2.8% from gasoline, LPG and diesel vehicles, respectively. The emission ratio from mobile source occupied 65% and 30% of total benzene emissions in USA and UK, respectively. In case of Korea, the emission ratio of benzene from mobile source occupied 29% (15% from on-road source, 14% from non-road source) which showed similar value with UK.
Lab scale experimental study was carried out for SBR process, to investigate the effects of influent ship sewage organic compound removal and Bacillus sp. state on design parameters. This process was able to remove nitrogen and phosphorus as well as organic matter efficiently. More than $92.0\%$ of chemical oxygen demand(COD) were removed. In addition, about $84.0\%$ of total nitrogen (T-N) was reduced. The total phosphorus(T-P) reduction averaged $93\%$. The performance load of SBR process was shown to be $0.095kg{\cdot}TOC/m3{\cdot}day$. The pH was decreased from 8.1 to 7.0 within 30 min and increased to 7.3 at the end of anoxic stage, and these phenomena were explained. The sludge produced in the SBR process is characterized by low generation rate (about $0.36kg{\cdot}MLSS/kg{\cdot}TOC$) and excellent settleability. The number of Bacillus sp. in the SBR was $24.2\%$, indicating that Bacillus sp. was a predominant species in the reactor.
The computing systems of today expanded business trade and distributed business process Internet. More and more systems are developed from components with exactly reusability, independency, and portability. Component based development is focused on advanced concepts rater than passive manipulation or source code in class library. The primary component construction in CBD. However, lead to an additional cost for reconstructing the new component with CBD model. It also difficult to serve component information with rapidly and exactly, which normalization model are not established, frequency user logging in Web caused overload. A lot of difficult issues and aspects of Component Based Development have to be investigated to develop good component-based products. There is no established normalization model which will guarantee a proper treatment of components. This paper elaborates on some of those aspects of web application to adapt user requirement with exactly and rapidly. Distributed components in this paper are used in the most tiny size on network and suggest the network-addressable interface based on business domain. We also discuss the internal and external specifications for grasping component internal and external relations of user requirements to be analyzed. The specifications are stored on Servlets after dividing the information between session and entity as an EJB (Enterprise JavaBeans) that are reusable unit size in business domain. The reusable units are used in business component through query to get business component. As a major contribution, we propose a systems model for registration, auto-arrange, search, test, and download component, which covers component reusability and component customization.
Introduction: While uncommon, humeral head osteonecrosis is an indication for arthroplasty when the humeral head collapse is advanced. The current authors report the short-term clinical results of 7 hemiarthroplasties to treat humeral head osteonecrosis. Materials and Methods: This study focused on 7 reconstructed shoulders of 5 patients whose humeral head osteonecrosis was treated with hemiarthroplasty. The postulated causes were alcohol-induced (4 cases) and steroidinduced (3 cases). The minimum follow-up was 12 months. This study compared the preoperative and postoperative shoulder pain, range of motion, and ASES scores. The postoperative patient satisfaction was assessed. Results: The level of pain during exercise was reduced from a preoperative average of 7.6 to a postoperative average of 1.9. The range of motion, in terms of forward flexion, abduction, and external rotation, improved from preoperative averages of $105.7^{\circ}$, $80^{\circ}$, and $22.1^{\circ}$ to postoperative averages of $146.6^{\circ}$, $139.3^{\circ}$, and $44.3^{\circ}$, respectively. The ASES scores increased from a preoperative mean of 39.0 to a postoperative mean of 84.1. The patients' ratings of the outcomes were excellent (5 cases) and good (2 cases). Conclusions: These short-term results indicate that hemiarthroplasty is a reliable treatment method for humeral head osteonecrosis improving shoulder pain, range of motion, and patient satisfaction.
Yoo, Han-Seok;Chung, Kang-Hyun;Lee, Kwon-Jai;Kim, Dong-Hee;An, Jeung Hee
Microbiology and Biotechnology Letters
/
v.43
no.4
/
pp.322-329
/
2015
The effects of water extracts of Gallus gallus var. domesticus (Yeonsan ogolgye, GD) on the activities of osteoblast differentiation and the restraint of osteoclast formation were investigated. The water extract of GD in the human osteoblast "MG-63" cell, was examined in relation to alkaline phosphatase (ALP) activity and alizarin red stains. In order to observe the effects of osteoclasts formation, we analyzed RAW 264.7 cell tartrate-resistant acid phosphatase (TRAP) activity and TRAP stains. The ALP activity of the water extract of hen and cock flesh (3 years) were 133.8% and 129.6%, respectively. The ALP activity of flesh extracts was also higher than that of the skin extracts. Concerning the effects of age, the 3 years old flesh extracts had a higher activity than that of the one year old extracts. However the activity of the 3 years old skin extracts was lower than that of the one year old extracts. For gender conditions, the ALP activity of the hen extract was higher than that of the cock. The degree bone mineralization in the three years old hen flesh exhibited the highest rate, at 124.3%, amongst all the groups. The TRAP activity of the flesh extracts of the three years old cock revealed the lowest rate, at 31.8%, compared to the control. Our results demonstrate that the water extract of GD increases bone mineralization and osteoblast differentiation activity in MG-63 cells and enhances the inhibitory activity of bone-resorption in RAW 264.7 cells. In conclusion, the water extracts of GD seem to be effective in the prevention and treatment of bone related disorders.
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