• YAKHAK HOEJI
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• v.56 no.1
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• pp.26-34
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• 2012

Mast cells play an important role in early and late phase allergic reactions through allergen and IgE-dependent release of histamine, proteases, prostaglandins, and several multifunctional cytokines. In this study, we investigated whether Cudrania tricuspidata extract (CTE) suppresses IgE-mediated allergic responses in mast cells, an allergic animal model, and its mechanism of action in mast cells. We found that CTE inhibited IgE-mediated degranulation and cytokine production in rat basophilic leukemia (RBL)-2H3 mast cells and bone marrow-derived mast cells (BMMC), as well as passive cutaneous anaphylaxis (PCA) in mice. With regard to its mechanism of action, CTE suppressed the activating phosphorylation of spleen tyrosine kinase (Syk), a key enzyme in mast cell signaling processes and that of LAT, a downstream adaptor molecule of Syk in $Fc{\varepsilon}RI$-mediated signal pathways. CTE also suppressed the activating phosphorylation of mitogen-activated protein (MAP) kinases and Akt. The present results strongly suggest that the anti-allergic activity of CTE is mediated through inhibiting degranulation and allergic cytokine secretion by inhibition of Syk kinase in mast cells. Therefore, CTE may be useful for the treatment of allergic diseases.

• ETRI Journal
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• v.34 no.3
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• pp.352-360
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• 2012

This paper proposes a low-cost, low-power, and high-capacity optical-electrical-optical-type reach extender that can provide 3R frame regeneration and remote management to increase the reach and split ratio with no change to a legacy time division multiple access passive optical network. To provide remote management, the extender gathers information regarding optical transceivers and link status per port and then transmits to a service provider using a simple network management protocol agent. The extender can also apply to an Ethernet passive optical network (E-PON) or a gigabit-capable PON (G-PON) by remote control. In a G-PON, in particular, it can provide burst mode signal retiming and burst-to-continuous mode conversion at the upstream path through a G-PON transmission convergence frame adaptor. Our proposed reach extender is based on the quad-port architecture for cost-effective design and can accommodate both the physical reach of 60 km and the 512 split ratios in a G-PON and the physical reach of 80 km and the 256 split ratios in an E-PON.

• Journal of the Korea Society of Computer and Information
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• v.21 no.1
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• pp.65-72
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• 2016

Network virtualization is an emerging technology for solving the rigidity of the physical network infrastructure. The innovative technique virtualizes all resources in the network, including the network links and nodes, and provides a number of virtual networks on a single network infrastructure. In order to realize a virtual network, a thorough and complete monitoring of all resources in the network should be performed firstly. OpenFlow is an open source stack for network virtualization. However, it is impossible to apply OpenFlow to AP-based legacy wireless LAN environment because OpenFlow targets ethernet-based LAN environment. In this paper, we implement an adaptor-styled virtual switch for AP-based wireless LAN through customizing the Open vSwitch which is a virtual switch of OpenFlow. The evaluation test results show that the implemented OpenFlow stack operates successfully. The implemented OpenFlow stack can now be plugged immediately in existing AP-based wireless LAN environment and plays network resource monitoring. In the future, we can develop wireless LAN virtualization applications on the wireless OpenFlow stack.

• Molecules and Cells
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• v.41 no.8
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• pp.753-761
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• 2018

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is identified as a signaling adaptor protein that regulates bone metabolism, immunity, and the development of several tissues. Therefore, its functions are closely associated with multiple diseases. TRAF6 is also involved in the regulation of hematopoiesis under steady-state conditions, but the role of TRAF6 in modulating hematopoietic stem and progenitor cells (HSPCs) during the developmental stages remains unknown. Here, we report that the deletion of TRAF6 in hematopoietic lineage cells resulted in the upregulation of HSPCs in the fetal liver at the prenatal period. However, in the early postnatal period, deletion of TRAF6 drastically diminished HSPCs in the bone marrow (BM), with severe defects in BM development and extramedullary hematopoiesis in the spleen being identified. In the analysis of adult HSPCs in a BM reconstitution setting, TRAF6 played no significant role in HSPC homeostasis, albeit it affected the development of T cells. Taken together, our results suggest that the role of TRAF6 in regulating HSPCs is altered in a spatial and temporal manner during the developmental course of mice.

• Journal of Korea Game Society
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• v.20 no.3
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• pp.3-14
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• 2020

The purpose of this paper is to analyze the factors effecting users' satisfaction on game AI for early AI diffusion. For this purpose, we interviewed 20 users who had experiences playing Blade&Soul, made by NCsoft. Interview data had been analyzed through the Semantic Network Analysis program to identify key subject words and their relations. As a result, the paper has found keywords such as patterns, contents, variety, system, and getting new users as factors effecting users satisfaction on game AI.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.499-502
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• 2011

The advances in Information Technology have made examining the condition of vehicles possible with using various functions of a Smart Phone. Users have not realized the necessity of auto diagnosis system, for previous system required professional knowledge about vehicles. Because of this inconvenience, special system which is easy to use and quick to grasp its condition by smart phone is asked for users. In this research, auto diagnosis system is designed in Windows Phone. The replacement cycles for auto consumables, examining vehicle problems, and information of eco driving indicator are delivered in real time for auto drivers by using OBD-II information which is through wifi module in OBD-II protocol adaptor connector.

• The Transactions of the Korean Institute of Power Electronics
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• v.16 no.4
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• pp.382-395
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• 2011

In this paper, for adapter with power level below approximately 60W, a novel LLC resonant converter preceded by diode rectifier with a capacitor filter is presented. Due to the switching operation of the auxiliary switching device, the proposed LLC resonant converter can deliver power with the high efficiency characteristics from the universal line($110V_{AC}$/ $220V_{AC}$) and load conditions. The operating schemes on the proposed converter are analyzed and described. A 60W prototype product is built, tested and verified.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.12C
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• pp.273-279
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• 2001

This paper describes a design and implementation of ISDN system on a chip which provides ISDN service and used to develop a low-price multimedia communication terminal. This ISDN SOC is an ISDN system control chip which has 32bit RISC processor, and it includes ISDN S interface transceiver, G.711 voice CODEC, PC interface for data communication, ISDN protocol which includes Q.931 call control protocol and internet protocol. It provides good solution to develope ISDN terminal equipment and ISDN terminal adaptor which connected with basic rate interface, because it minimize external peripheral devices.

• The Transactions of the Korean Institute of Power Electronics
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• v.19 no.4
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• pp.357-363
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• 2014

A programmable smart charger compatible to various load conditions is proposed in this paper. Since the proposed smart charger is compatible to various mobile devices having different rated voltage and power, it is convenient for carrying and easy to standardize many kinds of battery chargers. Moreover, since it uses the input impedance and built-in PMIC (Power management IC) of the load system to recognize the connection state and specifications of load system, hardware changes of load system is not only hardly necessary but it also features no addition communication cable and easy implementation. To confirm the validity of the proposed charger, the theoretical analysis and experiment results from a prototype compatible to three load conditions 5V/1A, 5V/2A and 12V/1A are provided.

• Proceedings of the KIPE Conference
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• 2014.07a
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• pp.173-174
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• 2014

본 논문에서는 저 대기전력 구현이 가능하며 정확한 출력전압 제어가 가능한 SSR(Secondary Side Regulator) 플라이백 컨버터를 제안하였다. 제안 SSR 플라이백 컨버터는 2차 측에 control IC를 사용하여 별도의 제어기(TL431) 및 포토커플러를 제거하여 구조가 간단하고 대기모드 시 TL431의 바이어스 전류에 의한 전력소모를 줄일 수 있으므로 대기전력을 최소화 할 수 있으며 출력전압을 직접 검출하여 정확하게 출력을 제어할 수 있다. 한편 1차 측의 위치한 게이트 구동을 위해 절연된 1-2차 측간 신호를 전송하는 PET(Pulse Edge Transmitter)를 제안하였으며 제안 방식은 IC로의 직접화가 매우 용이하여 1-2차 측 IC와 제안 PET를 one-chip화 할 수 있다. 제안 회로의 타당성 검증을 위해 10W급 Adaptor의 시작품을 제작하였고, 이를 이용한 실험결과를 바탕으로 제안 시스템의 타당성을 검증한다.