• Title/Summary/Keyword: Adaptive defense mechanism

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The Mediating Effect of Defense Mechanism in the Relation between Disconnection and rejection Schema and Mental Health (단절 및 거절 도식과 정신건강 간의 관계에서 방어기제의 매개효과)

  • KIM, Haeng-Shin;SEO, Su-Gyun
    • Journal of Fisheries and Marine Sciences Education
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    • v.27 no.3
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    • pp.656-671
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    • 2015
  • The purpose of the present study is to examine relationships between disconnection and rejection schema, defense mechanism, and mental health in college students using structural equation modeling. The present study suggested a proposed model in which defense mechanism exerted a full mediating effect on the relation between disconnection and rejection schema and mental health. Goodness of fit tests were used to compare the proposed model against competing models. The subjects consisted of 304 college students. They completed the Young Schema Questionnaire(YSQ-SF), the Defense Style Questionnaire(DSQ), and the Mental Health Scale. The results showed that the second model had a better goodness of fit. Based on these findings, it is suggested that psychological interventions for mental health in college students should consider strategies to use more flexible and more adaptive defense mechanism style.

Analysis of Threat Model and Requirements in Network-based Moving Target Defense

  • Kang, Koo-Hong;Park, Tae-Keun;Moon, Dae-Sung
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.10
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    • pp.83-92
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    • 2017
  • Reconnaissance is performed gathering information from a series of scanning probes where the objective is to identify attributes of target hosts. Network reconnaissance of IP addresses and ports is prerequisite to various cyber attacks. In order to increase the attacker's workload and to break the attack kill chain, a few proactive techniques based on the network-based moving target defense (NMTD) paradigm, referred to as IP address mutation/randomization, have been presented. However, there are no commercial or trial systems deployed in real networks. In this paper, we propose a threat model and the request for requirements for developing NMTD techniques. For this purpose, we first examine the challenging problems in the NMTD mechanisms that were proposed for the legacy TCP/IP network. Secondly, we present a threat model in terms of attacker's intelligence, the intended information scope, and the attacker's location. Lastly, we provide seven basic requirements to develop an NMTD mechanism for the legacy TCP/IP network: 1) end-host address mutation, 2) post tracking, 3) address mutation unit, 4) service transparency, 5) name and address access, 6) adaptive defense, and 7) controller operation. We believe that this paper gives some insight into how to design and implement a new NMTD mechanism that would be deployable in real network.

Overview of Innate Immunity in Drosophila

  • Kim, Tae-Il;Kim, Young-Joon
    • BMB Reports
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    • v.38 no.2
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    • pp.121-127
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    • 2005
  • Drosophila protects itself from infection by microbial organisms by means of its pivotal defense, the so-called innate immunity system. This is its sole defense as it lacks an adaptive immunity system such as is found in mammals. The strong conservation of innate immunity systems in organisms from Drosophila to mammals, and the ease with which Drosophila can be manipulated genetically, makes this fly a good model system for investigating the mechanisms of virulence of a number of medically important pathogens. Potentially damaging endogenous and/or exogenous challenges sensed by specific receptors initiate signals via the Toll and/or Imd signaling pathways. These in turn activate the transcription factors Dorsal, Dorsal-related immune factor (Dif) and Relish, culminating in transcription of genes involved in the production of antimicrobial peptides, melanization, phagocytosis, and the cytoskeletal rearrangement required for appropriate responses. Clarifying the regulatory interactions between the various pathways involved is very important for understanding the specificity and termination mechanism of the immune response.

Turfgrass Responses to Water Deficit: A Review (물 부족 현상으로 인한 잔디의 생리학적 반응: 리뷰)

  • Lee, Joon-Hee
    • Asian Journal of Turfgrass Science
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    • v.25 no.2
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    • pp.125-132
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    • 2011
  • Drought is a major limiting factor in turfgrass management. Turfgrass responses to water deficit depend on the amount and the rate of water loss as well as the duration of the stress condition. This review paper was designed to understand responses such as photosynthesis, canopy spectral reflectance, plant cell, root, hormone and protein alteration when turfgrass got drought stress. Furthermore, mechanisms to recover from drought conditions were reviewed in detail. However, there are still many questions regarding plant adaptation to water deficit. It is not clear that the mechanism by which plants detect water deficit and transfer that signal into adaptive responses. Turfgrass research should focus on the best management practices such as how to enhance the ability of self-defense mechanism through understanding plant responses by environmental stress.

The Emerging Role of Natural Killer Cells in Innate and Adaptive Immunity

  • Kim, Eun-Mi;Ko, Chang-Bo;Myung, Pyung-Keun;Cho, Daeho;Choi, Inpyo;Kang, Hyung-Sik
    • IMMUNE NETWORK
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    • v.4 no.4
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    • pp.205-215
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    • 2004
  • In the early host defense system, effector function of natural killer (NK) cells results in natural killing against target cells such as microbe-infected, malignant, and certain allogenic cells without prior stimulation. NK cell cytotoxicity is selectively regulated by homeostatic prevalence between a repertoire of both activating and inhibitory receptors, and the discrimination of untransformed cells is achieved by recognition of major histocompatibility complex (MHC) class I alleles through inhibitory signals. Although it is well known that the bipotential T/NK progenitors are derived from the common precusor, functional mechanisms in terms of the development of NK cells remain to be further investigated. NK cells are mainly involved in innate immunity, but recent studies have been reported that they also play a critical role in adaptive immune responses through interaction with dendritic cells (DC). This interaction will provide effector functions and development of NK cells, and elucidation of its precise mechanism may lead to therapeutic strategies for effective treatment of several immune diseases.

A Slot Allocated Blocking Anti-Collision Algorithm for RFID Tag Identification

  • Qing, Yang;Jiancheng, Li;Hongyi, Wang;Xianghua, Zeng;Liming, Zheng
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.6
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    • pp.2160-2179
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    • 2015
  • In many Radio Frequency Identification (RFID) applications, the reader recognizes the tags within its scope repeatedly. For these applications, some algorithms such as the adaptive query splitting algorithm (AQS) and the novel semi-blocking AQS (SBA) were proposed. In these algorithms, a staying tag retransmits its ID to the reader to be identified, even though the ID of the tag is stored in the reader's memory. When the length of tag ID is long, the reader consumes a long time to identify the staying tags. To overcome this deficiency, we propose a slot allocated blocking anti-collision algorithm (SABA). In SABA, the reader assigns a unique slot to each tag in its range by using a slot allocation mechanism. Based on the allocated slot, each staying tag only replies a short data to the reader in the identification process. As a result, the amount of data transmitted by the staying tags is reduced greatly and the identification rate of the reader is improved effectively. The identification rate and the data amount transmitted by tags of SABA are analyzed theoretically and verified by various simulations. The simulation and analysis results show that the performance of SABA is superior to the existing algorithms significantly.

Energy-efficient Routing in MIMO-based Mobile Ad hoc Networks with Multiplexing and Diversity Gains

  • Shen, Hu;Lv, Shaohe;Wang, Xiaodong;Zhou, Xingming
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.2
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    • pp.700-713
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    • 2015
  • It is critical to design energy-efficient routing protocols for battery-limited mobile ad hoc networks, especially in which the energy-consuming MIMO techniques are employed. However, there are several challenges in such a design: first, it is difficult to characterize the energy consumption of a MIMO-based link; second, without a careful design, the broadcasted RREP packets, which are used in most energy-efficient routing protocols, could flood over the networks, and the destination node cannot decide when to reply the communication request; third, due to node mobility and persistent channel degradation, the selected route paths would break down frequently and hence the protocol overhead is increased further. To address these issues, in this paper, a novel Greedy Energy-Efficient Routing (GEER) protocol is proposed: (a) a generalized energy consumption model for the MIMO-based link, considering the trade-off between multiplexing and diversity gains, is derived to minimize link energy consumption and obtain the optimal transmit model; (b) a simple greedy route discovery algorithm and a novel adaptive reply strategy are adopted to speed up path setup with a reduced establishment overhead; (c) a lightweight route maintenance mechanism is introduced to adaptively rebuild the broken links. Extensive simulation results show that, in comparison with the conventional solutions, the proposed GEER protocol can significantly reduce the energy consumption by up to 68.74%.

Autophagy and Digestive Disorders: Advances in Understanding and Therapeutic Approaches

  • Thein, Wynn;Po, Wah Wah;Choi, Won Seok;Sohn, Uy Dong
    • Biomolecules & Therapeutics
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    • v.29 no.4
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    • pp.353-364
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    • 2021
  • The gastrointestinal (GI) tract is a series of hollow organs that is responsible for the digestion and absorption of ingested foods and the excretion of waste. Any changes in the GI tract can lead to GI disorders. GI disorders are highly prevalent in the population and account for substantial morbidity, mortality, and healthcare utilization. GI disorders can be functional, or organic with structural changes. Functional GI disorders include functional dyspepsia and irritable bowel syndrome. Organic GI disorders include inflammation of the GI tract due to chronic infection, drugs, trauma, and other causes. Recent studies have highlighted a new explanatory mechanism for GI disorders. It has been suggested that autophagy, an intracellular homeostatic mechanism, also plays an important role in the pathogenesis of GI disorders. Autophagy has three primary forms: macroautophagy, microautophagy, and chaperone-mediated autophagy. It may affect intestinal homeostasis, host defense against intestinal pathogens, regulation of the gut microbiota, and innate and adaptive immunity. Drugs targeting autophagy could, therefore, have therapeutic potential for treating GI disorders. In this review, we provide an overview of current understanding regarding the evidence for autophagy in GI diseases and updates on potential treatments, including drugs and complementary and alternative medicines.

Adaptive Consensus Bound PBFT Algorithm Design for Eliminating Interface Factors of Blockchain Consensus (블록체인 합의 방해요인 제거를 위한 Adaptive Consensus Bound PBFT 알고리즘 설계)

  • Kim, Hyoungdae;Yun, Jusik;Goh, Yunyeong;Chung, Jong-Moon
    • Journal of Internet Computing and Services
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    • v.21 no.1
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    • pp.17-31
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    • 2020
  • With the rapid development of block chain technology, attempts have been made to put the block chain technology into practical use in various fields such as finance and logistics, and also in the public sector where data integrity is very important. Defense Operations In addition, strengthening security and ensuring complete integrity of the command communication network is crucial for operational operation under the network-centered operational environment (NCOE). For this purpose, it is necessary to construct a command communication network applying the block chain network. However, the block chain technology up to now can not solve the security issues such as the 51% attack. In particular, the Practical Byzantine fault tolerance (PBFT) algorithm which is now widely used in blockchain, does not have a penalty factor for nodes that behave maliciously, and there is a problem of failure to make a consensus even if malicious nodes are more than 33% of all nodes. In this paper, we propose a Adaptive Consensus Bound PBFT (ACB-PBFT) algorithm that incorporates a penalty mechanism for anomalous behavior by combining the Trust model to improve the security of the PBFT, which is the main agreement algorithm of the blockchain.

Differentially Up-expressed Genes Involved in Toluene Tolerance in Pseudomonas sp. BCNU106 (유기용매 내성 세균 Pseudomonas sp. BCNU106 균주에서 차별적으로 상향 발현되는 유전자군의 톨루엔 내성과의 연관성)

  • Joo, Woo Hong;Bae, Yun-Ui;Kim, Da Som;Kim, Dong Wan
    • Journal of Life Science
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    • v.30 no.1
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    • pp.88-95
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    • 2020
  • Using a random arbitrarily primed polymerase chain reaction, messenger RNA expression levels were assessed after exposure to 10% (v/v) toluene for 8 hr in solvent-tolerant Pseudomonas sp. BCNU 106. Among the 100 up-expressed products, 50 complementary DNA fragments were confirmed to express repeatedly; these were cloned and then sequenced. Blast analysis revealed that toluene stimulated an adaptive increase in the gene expression level in association with transcriptions such as LysR family of transcriptional regulators and RNA polymerase factor sigma-32. The expression of catalase and Mn2+/Fe2+ transporter genes functionally associated with inorganic ion transport and metabolism increased, and the increased expression of type IV pilus assembly PilZ and multi-sensor signal transduction histidine kinase genes, functionally categorized into signal transduction and mechanisms, was also demonstrated under toluene stress. The gene expression level of beta-hexosaminidase in association with carbohydrate transport and metabolism increased, and those of DNA polymerase III subunit epsilon, DNA-3-methyladenine glycosylase II, DEAD/DEAH box helicase domain-containing protein, and ABC transporter also increased after exposure to toluene in DNA replication, recombination, and repair, and even in defense mechanism. In particular, the RNAs corresponding to the ABC transporter, Mn2+/Fe2+ transporter, and the β-hexosaminidase gene were confirmed to be markedly induced in the presence of 10% toluene. Thus, defense mechanism, cellular ion homeostasis, and biofilm formation were shown as essential for toluene tolerance in Pseudomonas sp. BCNU 106.