• Journal of Life Science
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• v.17 no.12
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• pp.1717-1722
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• 2007

In the present study, all of the treadmill exercise-trained SHR expressed clear adaptive changes such as reduced resting heart rate and blood pressures, LPOA, homocysteine Therefore, treadmill exercise was sufficient to induce physiological adaptation in the SHR. Endurance training is known to induce physiological cardiac hypertrophy, while hypertension induces patho logical cardiac hypertrophy that increases cardiomyocyte apoptosis. The pathological adaptation to pressure overload has also been associated with a further increase in the expression of several marker genes including cardiomyocyte ET-1 in the SHR, but not in the exercise-trained SHR. Additionally, there is an increase in the endothelial nitricoxide synthases (eNOS) protein expression of soleus, gastrocnemius, and extensor digitorum longus muscle in the exercise-trained SHR but not in the SHR in the present study. Thus, compared to pathological adaptation to pressure overload, physiological adaptation to exercise training is associated with distinct alterations in cardiac and molecular phenotypes. based on these results, exercise training improves hypertension by cardiovascular regulating genes and hemodynamic parameters.

• Journal of the Korea Convergence Society
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• v.8 no.12
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• pp.445-450
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• 2017

Recently, at university, the number of international students from China is increasing, and we want to improve their adaptation to college life, In this research, we applied a fusion program of the tea ceremony to respect and to enhance true self through tea culture for Chinese students and seeing the tea ceremony application in Chinese. The targeting 10 international students in T University of P City have participated directly to the tea ceremony experience program once a week for 4 sessions, and watching the tea ceremony app twice or more everyday for 30 days. As the result, the average stress score of cultural adaptation of Chinese students before participating in the program was 98.5 (SD 9.63), and after participating in the program that was 93.9 (SD 9.67). And it was confirmed that the stress score level of cultural adaptation before and after participation in the program was significantly different (Z=6.702***, P=.000). Therefore, this program can be effective to reduce the cultural adaptation stress to Chinese students.

• Child Health Nursing Research
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• v.27 no.3
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• pp.201-210
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• 2021

Purpose: This study analyzed research trends related to childhood and adolescent cancer survivors (CACS) using word co-occurrence network analysis on studies registered in the Korean Citation Index (KCI). Methods: This word co-occurrence network analysis study explored major research trends by constructing a network based on relationships between keywords (semantic morphemes) in the abstracts of published articles. Research articles published in the KCI over the past 10 years were collected using the Biblio Data Collector tool included in the NetMiner Program (version 4), using "cancer survivors", "adolescent", and "child" as the main search terms. After pre-processing, analyses were conducted on centrality (degree and eigenvector), cohesion (community), and topic modeling. Results: For centrality, the top 10 keywords included "treatment", "factor", "intervention", "group", "radiotherapy", "health", "risk", "measurement", "outcome", and "quality of life". In terms of cohesion and topic analysis, three categories were identified as the major research trends: "treatment and complications", "adaptation and support needs", and "management and quality of life". Conclusion: The keywords from the three main categories reflected interdisciplinary identification. Many studies on adaptation and support needs were identified in our analysis of nursing literature. Further research on managing and evaluating the quality of life among CACS must also be conducted.

• Korean Journal of Culture and Arts Education Studies
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• v.13 no.3
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• pp.81-109
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• 2018

This study aims to identify research trends in adaptation of young children from multicultural families in order to provide insights for researchers around research topics and cultural adaptation orientation of young children from multicultural families. Subjects of this study were 41 literatures with key words of'young children from multicultural families', 'adaptation', and'life'through paper search system. This study was analysed the research themes, methods, subjects, and perspectives of cultural adaptation in adaptation researches of young children from multicultural families, 2006-2017 from peer reviewed journals with analysis frameworks. The results showed that : (a) the most common research topic continues to be about adaptation conditions of young children from multicultural families; (b) among research methods, quantitative research has most frequently used in, followed by qualitative methods, mixed methods, and literature review; (c) cultural adaptation was focused on the perspective of social-cultural adaptation, developmental importance of adaptation in early childhood and problems-based research. It implicated that further researches are need to focused on psychological adaptation and formation of classroom community beyond personal and structural adaptation in preschools.

• Journal of Korean Home Economics Education Association
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• v.26 no.2
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• pp.15-30
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• 2014

The purpose of this study is to provide basic information on clothing preference to help teachers suggest clothes that help students adapt better to school life, and to get basic data specific to Home Economics curricula and how teenagers' attitude toward clothes correlate with their conformity to school as a whole. The survey of 587 students was conducted between December 17-24, 2012 in Gwangju. The data was analyzed using the SPSS 18.0 for window program: frequency, means, factor analysis, cluster analysis, Chronbach's ${\alpha}$, t-test, and ANOVA. There were significant differences in the many adolescents's adapted to school life based on the clothing behavior conformity and the attitude toward the name-brand. The results showed that, if it is not extreme, adolescents had the more the clothing behavior conformity on peer & mass media than less, they did well adapt on school life. And the group of more preference for the name-brand clothing result in low school discipline adaptation but high peer and teacher relationship. In adaptation of learning, they were not different significantly based on attitudes toward the name brand.

• Journal of muscle and joint health
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• v.8 no.2
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• pp.230-249
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• 2001

This study was conducted to investigate the affecting factors on the adaptation to uncertainty in patients having rheumatoid arthritis. Subjects of the study constituted 222 patients who visited outpatient of rheumatic center in Seoul. Self report questionnaires were used to measure the variables affecting the adaptation to uncertainty. The variables affecting the adaptation to uncertainty were uncertainty, mastery, appraisal of danger, appraisal of opportunity, emotion focused coping, problem focused coping, pain, depression and activity of daily life(ADL). Reliability coefficients of these instruments were found Cronbach's $Alpha\;=\;.70{\sim}.94$. In data analysis, SPSSWIN 10.0 program was utilized for descriptive statistics, Pearson's correlation, and multiple regression analysis. The results were as follows. 1) The range of total pain scores was from 0 to 147 and the mean score of the pain in rheumatoid arthritis patients was 72.64. 2) The range of total depression scores was from 20 to 72 and the mean score of the depression in rheumatoid arthritis patients was 39.86. 3) The range of total ADL scores was from 22 to 80 and the mean score of the ADL in rheumatoid arthritis patients was 72.56. 4) Among the independent variables, significant factors to explain the adaptation to pain in patients were danger appraisal of uncertainty(p<.05) and emotion focused coping(p<.05). 5) Among the independent variables, significant factors to explain the adaptation to depression in patients were danger appraisal of uncertainty(p<.001), opportunity appraisal of uncertainty(p<.001) and mastery(p<.005). 6) Among the independent variables, significant factors to explain the adaptation to ADL in patients were mastery(p<.001) and danger appraisal of uncertainty(p<.05).

• Journal of Korean Academy of Nursing
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• v.45 no.5
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• pp.694-703
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• 2015

Purpose: This study was a prospective longitudinal study to identify changes in quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT). It was based on Roy's adaptation model. Methods: The questionnaires were administered before HSCT, 30 and 100 days after HSCT. Of the 48 potentially eligible patients, 44 (91.7%) participated in the study and 40 (90.9%) completed the questionnaires at 100 days after HSCT. Multilevel analysis was applied to analyze changes in quality of life. Results: Overall, quality of life showed a decreasing tendency from pre-HSCT to 100 days after HSCT. The adaptation level of participants was compensatory. Type of conditioning was the significant factor influencing quality of life before HSCT (${\beta}_{00}$=79.92, p <.001; ${\beta}_{01}$= - 12.64, p <.001) and the change rate of quality of life (${\beta}_{10}$= - 1.66, p =.020; ${\beta}_{11}$=2.88, p =.014). Symptom severity (${\beta}_{20}$= - 1.81, p =.004), depression (${\beta}_{30}$= - 0.58, p =.001), social dependency (${\beta}_{40}$= - 0.35, p =.165), and loneliness (${\beta}_{50}$= - 0.23, p =.065) had a negative effect on changes in quality of life. Symptom severity and depression were statistically significant factors influencing changes in quality of life. Conclusion: According to the results of this study, the development of nursing intervention is needed to improve quality of life in patients undergoing allogeneic hematopoietic stem cell transplantation in the early immune reconstruction period. The interventions should include programs to enhance coping capacity and programs to help control symptom severity and depression. Also these interventions need to be started from the beginning of HSCT and a multidisciplinary approach would be helpful.

• BMB Reports
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• v.47 no.1
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• pp.15-20
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• 2014

Intracellular lipid-binding proteins (LBPs) impact fatty acid homeostasis in various ways, including fatty acid transport into mitochondria. However, the physiological consequences caused by mutations in genes encoding LBPs remain largely uncharacterized. Here, we explore the metabolic consequences of lbp-5 gene deficiency in terms of energy homeostasis in Caenorhabditis elegans. In addition to increased fat storage, which has previously been reported, deletion of lbp-5 attenuated mitochondrial membrane potential and increased reactive oxygen species levels. Biochemical measurement coupled to proteomic analysis of the lbp-5(tm1618) mutant revealed highly increased rates of glycolysis in this mutant. These differential expression profile data support a novel metabolic adaptation of C. elegans, in which glycolysis is activated to compensate for the energy shortage due to the insufficient mitochondrial ${\beta}$-oxidation of fatty acids in lbp-5 mutant worms. This report marks the first demonstration of a unique metabolic adaptation that is a consequence of LBP-5 deficiency in C. elegans.

• The Journal of Korean Physical Therapy
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• v.26 no.2
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• pp.90-96
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• 2014

Purpose: The aim of the study was to develop the Korean version of the Working Alliance Inventory (KWAI) and to assess reproducibility of both its therapist and client forms. Methods: The 12-item WAI was translated into Korean. The translation procedure followed the guidelines proposed by Beaton et al. (2000). Development of KWAI involved its translation, back-translation, and pilot testing of the pre-final version to establish Korean cultural adaptation of the original version of WAI. For test-retest reliability, therapists (N=30) and clients (N=47) completed the questionnaire on two different occasions. The interval between occasions was two to seven days, depending on subject availability. Data were collected from clinicians working in general hospitals and private clinics, and clients who had received treatment within three months. The intra-class correlation (ICC ($_{2.1}$)) was calculated for assessment of the reproducibility of the translated questionnaire. Results: The test-retest ICC ($_{2.1}$) of the client form and the therapist form was 0.92 (95%CI:0.86-0.95) and 0.94 (95%CI:0.89-0.97), respectively. Answers to items 2, 8, and 11 showed a tendency to be omitted due to ambiguity of meaning in Korean. Idiomatic expression was employed rather than word-to-word translation to have clear meaning of those items. Conclusion: The KWAI was successfully translated and adapted for applications to Korean clients and therapists, with a satisfactory level of reliability. Therefore, it can be suggested that the KWAI is useful in providing a reliable assessment of working alliance between therapists and clients.

• Mycobiology
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• v.42 no.1
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• pp.52-58
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• 2014

A nucleoside diphosphate-linked moiety X (Nudix) hydrolase-like gene, YSA1, has been identified as one of the gromwell plant extract-responsive genes in Cryptococcus neoformans. Ysa1 is known to control intracellular concentrations of ADP-ribose or O-acetyl-ADP-ribose, and has diverse biological functions, including the response to oxidative stress in the ascomycete yeast, Saccharomyces cerevisiae. In this study, we characterized the role of YSA1 in the stress response and adaptation of the basidiomycete yeast, C. neoformans. We constructed three independent deletion mutants for YSA1, and analyzed their mutant phenotypes. We found that ysa1 mutants did not show increased sensitivity to reactive oxygen species-producing oxidative damage agents, such as hydrogen peroxide and menadione, but exhibited increased sensitivity to diamide, which is a thiol-specific oxidant. Ysa1 was dispensable for the response to most environmental stresses, such as genotoxic, osmotic, and endoplasmic reticulum stress. In conclusion, modulation of YSA1 may regulate the cellular response and adaptation of C. neoformans to certain oxidative stresses and contribute to the evolution of antifungal drug resistance.