• Animal cells and systems
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• 제8권2호
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• pp.125-133
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• 2004

We have extended our previous work that cross-linking CD4 molecules using specific MAb induced antigen nonspecific, MHC unrestricted killing of virally infected target cells by CD$4^+$We have extended our previous work that cross-linking CD$4^+$ molecules using specific MAb induced antigen nonspecific, MHC unrestricted killing of virally infected target cells by CD$4^+$ T cells. The killing activity of antibody activated CD$4^+$T cells was completely blocked by herbimycin A, a protein tyrosine kinase (PTK) inhibitor, but not by bisindolylamaleimide, a protein kinase C (PKC) inhibitor. Herbimycin A treated human or bovine peripheral blood CD$4^+$T cells lacked PTK activity and failed to kill virally infected target cells even after cross-linking of CD4 molecules. The CD$4^+$cross-linking failed to induce effector cell proliferation or the transcription of TNF${\beta}$ Upregulation of TNF${\beta}$ was induced by incubating the antibody activated effector cells with BHV-1 infected D17 target cells for 10 h. Anti-TNF${\beta}$ antibody partially abolished (13-44%) the direct effector cell-mediated antiviral cytotoxicity. However, this antibody neutralized 70 to 100% of antiviral activity of effector and target cell culture supernatants against BHV-1 infected D17 cells. The inhibition level of the antiviral activity by the antibody was dependent on the effector and target cell ratio. These results support the hypothesis that increased p$56^ICK enzyme activity in effector cells transduces a signal critical for effector cell recognition of viral glycoproteins expressed on the target cells. Following target cell recognition, lytic cytokines known to participate in target cell killing were produced. A better understanding of the killing activity displayed by CD$4^+$T lymphocytes following surface receptor cross-linking will provide insight into the mechanisms of cytotoxic activity directed toward virally-infected cells.T cells. The killing activity of antibody activated CD$4^+$T cells was completely blocked by herbimycin A, a protein tyrosine kinase (PTK) inhibitor, but not by bisindolylamaleimide, a protein kinase C (PKC) inhibitor. Herbimycin A treated human or bovine peripheral blood CD4T cells lacked PTK activity and failed to kill virally infected target cells even after cross-linking of CD4molecules. The CD4 cross-linking failed to induce effector cell proliferation or the transcription of TNF$\beta$. Upregulation of TNF$\beta$ was induced by incubating the antibody activated effector cells with BHV-1 infected D17 target cells for 10 h. Anti-TNF$\beta$ antibody partially abolished (13-44%) the direct effector cell-mediated antiviral cytotoxicity. However, this antibody neutralized 70 to 100% of antiviral activity of effector and target cell culture supernatants against BHV-1 infected D17 cells. The inhibition level of the antiviral activity by the antibody was dependent on the effector and target cell ratio. These results support the hypothesis that increased $56^ICK enzyme activity in effector cells transduces a signal critical for effector cell recognition of viral glycoproteins expressed on the target cells. Following target cell recognition, lytic cytokines known to participate in target cell killing were produced. A better understanding of the killing activity displayed by CD$4^+$T lymphocytes following surface receptor cross-linking will provide insight into the mechanisms of cytotoxic activity directed toward virally-infected cells.

• 한국멀티미디어학회논문지
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• 제15권4호
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• pp.417-424
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• 2012

In this paper, we propose an automatic system that recognizes dynamic human gestures activity, including Arabic numbers from 0 to 9. We assume the gesture trajectory is almost in a plane that called principal gesture plane, then the Least Squares Method is used to estimate the plane and project the 3-D trajectory model onto the principal. An improved FNN model combined with HMM is proposed for dynamic gesture recognition, which combines ability of HMM model for temporal data modeling with that of fuzzy neural network. The proposed algorithm shows that satisfactory performance and high recognition rate.

• Bulletin of the Korean Chemical Society
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• 제33권5호
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• pp.1703-1706
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• 2012

Rice blast is the most serious disease of rice due to its harmfulness and its world wide distribution. $Magnaporthe$ $grisea$ is the cause of rice blast disease and destroys rice enough to feed several tens of millions of people each year. Fungicides are commonly used to control rice blast. But $M.$ $grisea$ acquires resistance to chemical treatments by genetic mutations. 2-Phenylimino-1,3-thiazolines were proposed as a novel class of fungicides against $M.$ $grisea$ in the previous study. To develop compounds with a higher biological activity, a new series of 2-phenylimino-1,3-thiazolines was synthesized and its fungicidal activity was determined against $M.$ $grisea$. The QSAR analysis was carried out on a series of 2-phenylimino-1,3-thiazolines. The QSAR results showed the dependence of fungicidal activity on the structural and physicochemical features of 2-phenylimino-1,3-thiazolines. Our results could be used as guidelines for the study of the mode of action and further design of optimal fungicides.

• 한국환경교육학회지:환경교육
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• 제11권2호
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• pp.14-25
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• 1998

The Quality of human living depends on the environmental quality of the region sustaining the life. The environmental deterioration of the modern society is due to mechanical environmentalism. For the better quality of the life, The changes of recognition and attitude on the environments are required. These changes of mind are also important in environmental education for teenagers. The 7th national curriculum, officially anounced December 1998, focuses on the change of attitude to environments and practical behavior in real life for “Environments”, the environmental education curriculum in middle school. Basic elements of the curriculum are cultivation of the pro-environmental thinking, multi-levelling of teaching materials and methods, and encouraging of student participating activity. Actually, the curriculum construction is composed of stepped-levelling of teaching and learning, reasonable contents volume, encouraging of student practice, and suggesting of evaluation standards of textbook writing. Three main subjects of environmental education for middle school consist of (1) man and environment, (2) recognition of environmental problem, and (3) protection activity for environment. Methodology of environmental education can include multi-disciplinary approaches, variable teaching methods, and continuing evaluation of student practice and participation attitude. Environmental education for teenagers relating to the 7th national curriculum focuses on recognition of the environmental problems and practice activity in daily life. The recognition includes considering relationship of human life to environment, solving environmental problems in regional context, and development of comprehensive understanding concept of the environments. For the practice education, variable teaching methods, such as field survey and application of multi-media, are needed.

• 한국의류산업학회지
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• 제23권3호
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• pp.323-336
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• 2021

This study investigated the cognitive process of fashion design images through eye activity tracking. Differences in the cognitive process and gaze activity according to image elements were confirmed. The results of the study are as follows. First, a difference was found between groups in the gaze time for each section according to the model and design. Although model diversity is an important factor leading the interest of observers, the simplicity of the model was deemed more effective for observing the design. Second, the examination of the differences by segments regarding the gaze weight of the image area showed differences for each group. When a similar type of model is repeated, the proportion of face recognition decreases, and the proportion of design recognition time increases. Conversely, when the model diversity is high, the same amount of time is devoted to recognizing the model's face in all the processes. Additionally, there was a difference in the gaze activity in recognizing the same design according to the type of model. These results enabled the confirmation of the importance of the model as an image recognition factor in fashion design. In the fashion industry, it is important to find a cognitive factor that attracts and retains consumers' attention. If the design recognition effect is further maximized by finding service points to be utilized, the brand's sustainability is expected to be enhanced even in the rapidly changing fashion industry.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권7호
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• pp.3599-3619
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• 2019

In human activity recognition system both static and motion information play crucial role for efficient and competitive results. Most of the existing methods are insufficient to extract video features and unable to investigate the level of contribution of both (Static and Motion) components. Our work highlights this problem and proposes Static-Motion fused features descriptor (SMFD), which intelligently leverages both static and motion features in the form of descriptor. First, static features are learned by two-stream 3D convolutional neural network. Second, trajectories are extracted by tracking key points and only those trajectories have been selected which are located in central region of the original video frame in order to to reduce irrelevant background trajectories as well computational complexity. Then, shape and motion descriptors are obtained along with key points by using SIFT flow. Next, cholesky transformation is introduced to fuse static and motion feature vectors to guarantee the equal contribution of all descriptors. Finally, Long Short-Term Memory (LSTM) network is utilized to discover long-term temporal dependencies and final prediction. To confirm the effectiveness of the proposed approach, extensive experiments have been conducted on three well-known datasets i.e. UCF101, HMDB51 and YouTube. Findings shows that the resulting recognition system is on par with state-of-the-art methods.

• 아동학회지
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• 제26권6호
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• pp.321-334
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• 2005

This research investigated television and video viewing of young children in early childhood all-day program settings and teachers' recognition of its effects on young children through the survey of 452 early childhood teachers. The results show that television and video viewing is used as a whole group activity during transition period and/or waiting time activity for children who come earlier in the morning and remain late until closing time. It means television and video viewing at early childhood settings is mainly used as a group baby sitter or pacifier. Daily viewing time is about 44.02 minutes and early childhood teachers show low recognition of their role in children's viewing habits. Young children's viewing patterns and time are differed by teachers' variables so that young children of beginning teachers at small size settings appear more viewing time. Teachers show more negative recognition of television and video viewing on young children when they are older and have higher educational level and longer education experiences. The results also show that the more teachers have positive recognition on television and video viewing, the more young children are exposed to television and video viewing in their classes.

• 보건의료산업학회지
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• 제6권2호
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• pp.121-131
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• 2012

This study investigated the difference of the university students' recognition, attitude, and knowledge level of health by the health education in Daejeon and Chungnam province. First, in the survey analysis result regarding the health related recognition, the students who had attended lectures of health education were surveyed not only to have higher health related recognition than the students who did not have attended the lecture of health education, but also to appear meaningful in statistics by showing significance level p<0.05 in total score. Second, in the research regarding the health related attitude, the attendance or nonattendance of health education lecture were surveyed not to have high effect on the attitude of daily lives of the university students. Third, in the analysis of health related knowledge, the knowledge level between the students who had attended lectures of health education and who did not have attended the lecture of health education showed that the students who had attended lectures of health education got more excellent correct answer rate. In this survey result, the students who had attended lectures of health education showed higher health related recognition and knowledge than the students who had not attended lectures of health education.

• 한국컴퓨터정보학회논문지
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• 제24권8호
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• pp.95-103
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• 2019

According to the Statistics Korea in 2017, the 10 leading causes of death contain a cardiac disorder disease, self-injury. In terms of these diseases, urgent assistance is highly required when people do not move for certain period of time. We propose an unusual event detection algorithm to identify abnormal user behaviors using dust, vision and activity sensors in their houses. Vision sensors can detect personalized activity behaviors within the CCTV range in the house in their lives. The pattern algorithm using the dust sensors classifies user movements or dust-generated daily behaviors in indoor areas. The accelerometer sensor in the smartphone is suitable to identify activity behaviors of the mobile users. We evaluated the proposed pattern algorithms and the fusion method in the scenarios.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제15권1호
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• pp.72-76
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• 2009

최근 유비쿼터스 컴퓨팅에 대한 관심이 높아지면서 유비쿼터스 환경에서의 서비스를 위한 인간과 컴퓨터의 상호 작용, 특히 인간의 행동을 인식하는 연구가 활발히 진행되고 있다. 기존의 영상기반 연구와는 달리 모바일 환경에 적합하도록 가속도 센서, 생리신호 센서 등 다양한 센서들을 활용하여 사용자의 행동을 인식하는 기법이 연구되고 있다. 본 논문에서는 멀티모달 센서들을 통합하고 동적 베이지안 네트워크를 계층적으로 구성하여 사용자의 행동을 인식하는 방법을 제안한다. 연산량이 비교적 적은 베이지안 네트워크로 전반적인 사용자 행동을 추론하고 획득된 각 행동의 확률순으로 동적 베이지안 네트워크를 구성한다. 동적 베이지안 네트워크는 OVR(One-Versus-Rest) 전략으로 학습되며, 확률순으로 행동이 검증되어 임계치를 넘는 경우 선택된 행동보다 낮은 확률의 행동에 대한 동적 베이지안 네트워크를 검증하지 않아 추론 연산량을 줄인다. 본 논문에서는 가속도 센서와 생리적 신호 센서를 기반으로 총 8가지의 행동을 인식하는 문제에 제안하는 방법을 적용하여 평균적으로 97.4%의 분류 정확률을 얻었다.