• Journal of Dairy Science and Biotechnology
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• v.34 no.3
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• pp.165-172
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• 2016

Kefir, originating from Caucasus, is an acidic, alcoholic fermented milk product with little acidic taste and a creamy consistency. It is recognized in having beneficial effects infor the prevention and treatment of cancer. For example, Kefir has possesses a chemopreventative effect on carcinogenesis. There has recently been a strong focus on fermented milk foods containing a mixture of several functional organic substances and various probiotic microorganisms. Hence, the purpose of this review paper was to evaluate the scientific evidence for the effects of kefir on cancer prevention and treatment. Some of we analyzed and summarized data-relating to the effects of kefir on cancer. The cacers that kefir has an effect on are as follows: colon cancer, breast cancer, leukemia, sarcoma, skin cancer, gastric cancer. This review suggests that (1) kefir could be associated with cancer prevention, (2) kefir has beneficial effects in cancer treatment, and (3) kefir has various bioactive components including peptides, polysaccharides and sphingolipids, which contribute tofor itsthese anti-cancer properties. Furthermore, furthermore, studies were performed in order to obtain as to get the scientific evidence of kefir's anticancer activity: (1) improved protective effectiveness in vivo (human subjects or animal model), (2) isolation and identification of various bioactive components, and (3) mechanisms associated with beneficial effects.

• Journal of Korea Technology Innovation Society
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• v.12 no.4
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• pp.819-839
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• 2009

Proposed increases to the government's R&D budget should be discussed based on merits of meeting efficiency and effectiveness criteria. The evaluation of the national R&D budget and related programs are performed in two areas: a system of R&D budget coordination and allocation, and a system of R&D program performance. This paper mainly focuses on the operational areas of R&D budget evaluation system with a focus on their impact to efficiency and effectiveness. The core view point for a R&D budget evaluation system involves two directions: Firstly, to detail the relationships between the later stage (ex. post) activities such as, program survey, analysis, and program performance evaluation, with the budget evaluation. Secondly, to critically oversee all R&D coordination procedures with a different perspective. Budgeting is generally known as a serial process of policy making, planning and executing. It is highly desirable for the budget to be allocated to, and spent by, specific programs as planned, and that each plan be aligned with a specific policy. As such, a strong relevance between the program structure and budget code system is integral to successful execution. It should be performed using a decision making system which closely examines the link between policy and budget. It is also recommended that systematic relationships be maintained among budget coordination and allocation, performance evaluations of policy and program levels, and program survey and analysis system, and that their operational schedule should be reviewed comprehensively as a one integrated system. The National Science and Technology Council is expected to play a major and practical role as the center of policy planning and should be supported by the objective and unbiased system which covers overall process from policy making to program evaluation. Finally, increased utilization of contents, timely program survey and analysis, and accurate of activity scheduling of budget coordination and allocation, and diligent program performance evaluation all contribute towards a more efficient and effective overall evaluation system.

• Applied Biological Chemistry
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• v.11
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• pp.89-93
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• 1969

The strains selected in the previous paper were identified according to the manual of Aspergilli by Thom and Raper, and the preparation of the crude enzymes with the strains were investigated. The fermented fodders were made with wheat bran and chaffs containing 20% wheat bran by the strains, and the feeding experiments concerned was conducted. The results obtained are as follows: 1. The selected strains were identified as below; MC-9 was a similar strain of Aspergillus niger van Tieghem, MC-10 was a similar strain of Aspergillus flavus Link, MC-53 was a similar strain of Aspergillus penicilloides Spegazzini and MC-61 was a similar strain of Aspergillus niger mut Schiemanni n. comb. 2. Percentages of crude enzymes obtained from the dried matters of the wheat bran cultures were MC-9: 2.9%, MC-10: 3.9%, MC-53: 6.4% and MC-61:2.6%. And the cellulase activity of MC-9 was the most active among the crude enzymes as the same as the filtrates of wheat bran cultures. 3. As the results of the feeding experiments, changes of body weights showed no trends to be significant as compared with the control group, and the groups of MC-9 and MC-61 showed the increasing significance with P<0.05 in egg-laying rate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6236-6246
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• 2015

In the paper, we reduce non-pregnant conditions and improve impregnation rate by unmanned estrus detection and decide proper time for artificial insemination. It is too hard to detect estrus only by using activities, we develop unmanned estrus detection system that consist of RF activity sensors, cow management program and estrus detection algorithm that uses information of activities and breeding. We verify performance by experiments in four similar scale stockbreeding farmhouse. Each stockbreeding farmhouse breeds 87, 81, 93, 82 cows and expected estrus cows are 14, 19, 15, 17. In expected estrus cow, we fail in weak estrus detection - 3, 2, 1, 3 cows, but detect successfully normal estrus - 11, 17, 14, 14 cows. After artificial insemination, 10, 17, 13, 14 cows became pregnant successfully confirming that proposed unmanned estrus detection system is effective for deciding proper time for artificial insemination in normal estrus.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.2
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• pp.94-109
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• 2005

Objectives: This paper investigated the effects of 8 Constitution Acupuncture on Heart Rate Variability(HRV) and is intended to find out 8 Constitutional difference on Autonomous Function after 8 Constitution Acupuncture stimulation. Methods: The subjects were comprised of 42 volunteers(11 men and 31 women). The volunteers had acupunctured by 8 Constitution Acupuncture Therapy. HRV and Mean Heart Rate(MHR) were measured by TAS9v2.0(IEMBIO & Saerom, Korea) on two times: before and immediately after acupuncture stimulation. The SPSS 13.0 for windows was used for statistical analysis: Mann-Whitney U-test, Paired Samples T -test and Wilcoxon signed rank test were used to verify the results. Results: 1. There was no statistically significant difference on HRV and MHR between Sympathicotonia and Vagotonia before acupuncture. 2. In the whole subject, immediately after acupuncture stimulation, MHR showed a significant decrease(p<0.01) and Ln(TP), Ln(LF) and Ln(HF) showed a significant increase(p<0.05). But there was no significant difference in LHR. 3. Immediately after acupuncture stimulation, MHR showed a significant decrease and Ln(TP), Ln(HF), showed a significant increase in Pulmotonia(p<0.05), Ln(TP) showed a significant increase in Pancretonia(p<0.05),MHR showed a significant decrease and Ln(TP) showed a significant increase in Hepatonia(p<0.05), and MHR showed a significant decrease and Ln(TP), Ln(HF), showed a significant increase in cholecystonia(p<0.05). But there were no significant difference on HRV and MHR in Colonotonia and vesicotonia. Conclusion: The results suggest that 8 Constitution Acupuncture is associated with changed activity in sympathetic and parasympathetic nervous system. Further study is needed for investigating the effects of 8 Constitution Acupuncture on HRV and autonomic nervous system.

• Smart Media Journal
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• v.6 no.1
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• pp.61-67
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• 2017

A large number of people living in modern times prefer remaining unmarried or living alone independently for the reason of their own will or another person's will. This is because they dislike being interfered with by other persons or because there is a financial problem. This behavior has become mainstream in persons working for professional jobs, persons having a strong disposition toward individual activity or college students. In particular, career women pursuing their own comfortable life have the tendency to prefer single life. However, sometimes, they become a target of crime that targets and makes bad use of this point. For these reasons. Consequently, sometimes, they additionally install and use a security system such as door security guard at front door and so on. It is not so difficult to lock the door security guard at the front door. However, it is apt to be forgotten. And when they are on the bedspread before falling asleep, in case they should check whether the door security guard is locked or in case they should lock it, they should get up, go to the entrance, and check and lock the door security guard. They often don't lock the door security guard due to their feeling that it is all right because of annoyance and inconvenience. This paper is intended to work for safety from crime such as illegal housebreaking by more conveniently using the door security guard after designing and implementing a system that can remotely control the door security guard, using a smartphone as a method of resolving this annoyance and keeping life more safe.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.8
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• pp.379-384
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• 2017

In real software business environment, there are required to validate software quality in diverse usage range of software for many small & medium companies. Software quality means both qualities of production and process. In our situation, we focus on better process quality of a test organization than a whole organization. But even the original test maturity model (TMM) does not enough to apply with our domestic venture/small & medium companies. To solve this problem, we suggest the simplified test maturity model for our companies. We redefine this simplified model with the original TMM and a test process improvement next (TPI next) model. The previous models just have provided each definition of maturity level, goal and activity per each level, which not exists an assessment guideline and a formal assessing procedure. Due to this reasons, an assessor is difficult to assess the test organization without them. this paper suggest an assessment guideline of the simplified TMM and also define the procedure which is included with activities and byproducts. With these assessment guideline, an assessor can work possible to formally assess test organizations of small & medium companies, and with self assessment guideline they can be correctly provision before assessment of their organizations.

• The Transactions of the Korea Information Processing Society
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• v.5 no.8
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• pp.1960-1971
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• 1998

The researches and developments to provide multimedia communication services such as Video on Demand(VoDJ), real time video phonc and multipoint vidco conferencing on broadband ISDN environmcnts have been proceeded with activity. Specifications for Vol) services which is worked by Digital Audio-Visual Council(DAVIC) to support detail technologies including total service system that is consist of VoD server. delive[\! networl, and Set-Top Box(STB) had been already finished and ITU-T SG16 also recommended the standards of H.300 series terminal aspects for conversational multimedia services, But the architectures of multimedia tenninals recommended and specified by these organizations do not have an efficient st11lcture to provide all of retrieval, distrihution and conversational service due to a different point of view about multimedia terminals and services. In this paper, we analyzed the recornmendatio!E and the specifications of intemational public and private organizations like lTU-T, DAVIC and ATM forum. As a result of these analysis. we propose an efficient terminal architecture, and then we have designed, lmplemented the multimedia communication terminal for offering VoI) and real- time conversation ,,, functional module test according to the individual commumication service session and confirined the validiry or terminal implemented to be used on broadband ISDK environments.

• The KIPS Transactions:PartA
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• v.8A no.4
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• pp.517-522
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• 2001

The appearance of web technology has accelerated a role of the development of the multimedia technology, the computer communication technology and the multimedia application contents. And serveral researches of WBI (Web-based Instruction) system have combined the technology of the digital library and LOD. Recently WBI (Web-based Instruction) model which is based on web has been proposed in the part of the new activity model of teaching-learning. And the demand of the customized coursewares which is required from the learners is increased, the needs of the efficient and automated education agents in the web-based instruction are recognized. But many education systems that had been studied recently did not service fluently the courses which learners had been wanting and could not provide the way for the learners to study the learning weakness which is observed in the continuous feedback of the course. In this paper we propose "Design of Multi-agent System for Course Scheduling of Learner-oriented using Weakness Analysis Algorithm". First proposed system monitors learner's behaviors constantly, evaluates them, and calculates his accomplishment. From this accomplishment the multi-agent schedules the suitable course for the learner. And the learner achieves a active and complete learning from the repeated and suitable course.le course.

• Journal of Oriental Neuropsychiatry
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• v.19 no.1
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• pp.125-146
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• 2008

Objectives : The purpose of this study is to suggest for the following experimental study of dementia by reviewing recent oriental medicine journals that have been published since 2000. Methods: We have investigated various types of studies in relation to dementia through 90 articles that have been published from 2000 to 2007 in recent oriental medicine journals were registered Korea research foundation. Results and Conclusions : 1. Since 2000, 88 articles in relation to dementia have been published and almost of them are herbal medicine-centered studies. Also they show a tendency to increase every year. The journal of oriental neuropsychiatry carries the highest number of studies in relation to dementia. 2. According to the experimental paper, there are 30 cases of using herb simplexes, 48 cases of herb-combined prescription, and 10 cases of other ways. Especially 7 cases of using herb-combined prescription relation to Sasang constitution are all for the Taeumin. 3. There are 85 cases of Animal and cellular experimental, 60 cases of using pathologic model induced cytotoxic activity, a case of using L-NAME, 3 cases of 192 saporin, 4 cases of ibotenic acid, 10 cases of focal cerebral ischemia, 3 cases of alcohol-administered, and one case of natural degradation. 4. Moms water maze, Radial arm maze Passive avoidance learning model were using for examining learning and memory of model animal 5. We propose that following studies of dementia are to he investigated of the applied method of using siRNA with tranceduced gene, sample preparation by water-soaking, oriental medical diagnosis, standardization of differentiating symptom and herb simplexes, building the database by classified prescriptions, and experiment model which are based on precise examining mechanism with cell line as like mouse H19-7 hippocampus, rat HT22 hippocampus, astrocyte, microglia, using the model of animals at APP, PS1, BACE, CT99/PS1, APOE4, Tau, APP/PSI/Tau