• Magazine of the Korean Society of Agricultural Engineers
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• v.39 no.4
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• pp.55-63
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• 1997

Constructed wetland system which can be applied to the rural wastewater treatment system was examined by pilot plant in Kon-Kuk University. Hydraulic loading rate of wastewater was about 0.16m$^3$/m$^2$. day and theoretical detention time in the system was 1.38 days. The effluent of the septic tank for the school building was applied as inflow to the system. The influent concentration of DO was zero but effluent was up to 4.37mg/${\ell}$ which implies that oxygen was supplied enough from atmosphere by reaeration to support biological activity of the system. Average influent concentration of BOD was 104mg/${\ell}$ and effluent was 24mg/${\ell}$ with average removal rate of 76%. Average influent concentration of COD was 215mg/${\ell}$ and effluent was 63mg/${\ell}$ with average removal rate of 70 % . Average influent concentration of SS was 78mg/${\ell}$ and effluent was 10mg/${\ell}$ with average removal rate of 87%. Two components, BOD and SS, are regulated by law to keep maximum water quality standard of 80mg/${\ell}$ when daily outflow rate is less than 100$m^3$/day which is the case of most rural communities. Therefore, the results from the experiment showed that constructed wetland system can meet the water quality standard easily. Average influent concentration of total nitrogen was 165mg/lwhich is relatively higher than normal wastewater, and effluent was about 156mg/${\ell}$ with average removal rate of only 6%. Average influent concentration of total phosphorus was 41 mg/${\ell}$ and effluent was 6mg/${\ell}$ with average removal rate of 87%. Overall, constructed wetland system was thought to be effective to treat wastewater if nitrogen removal mechanism is improved. Considering low cost, less maintenance, and high treatability, this system can be a practical alternative for the wastewater treatment in rural area The experiment was performed during the summer and fall season, and treatment efficiency of the system is expected to decrease in low temperature. therefore, further study including temperature is required to evaluate feasibility of the system more in detail.

• Journal of Korean Library and Information Science Society
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• v.41 no.1
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• pp.295-318
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• 2010

Recently a reading education system has been developed to manage the accumulated reading activities and past records of individuals under the web environment using computers. And the reading education system, where we can have comprehensive reading education, has been developed and been applied to schools. The reading records in the reading education system can contribute to the improvement of reading activities and reading comprehension, the extension of thinking ability, and the cultivation of insight and character of the readers. The system will provide basic data for reading education for the teachers. The reading education system will accumulate the reading records of individuals. This system is not restricted by time and space. Also the system can support the reading education of children and students effectively. The menu of the reading education system is composed of a test of reading level, reading materials, activities after reading, reading certification, reading record management and instruction of teachers.

• Journal of Music and Human Behavior
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• v.6 no.1
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• pp.1-31
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• 2009

This study aims to conduct a music psychotherapy program on North Korean child defectors, who are experiencing acculturative stress, and to discover the effects of the program on the participants' acculturative stress. This study targeted four North Korean child defectors, who belonged to an H afterschool class in Seoul and performed the program in individual sessions for about 40 minutes per session, totaling 14 sessions. The research results include the following. First, after comparing the results of acculturative stress score that measured before and after the execution of the music psychotherapy program, the mean of the score was significantly decreased from 32.75 to 23 average. Furthermore, as a result of conducting a qualitative analysis of the lingual responses that the participants demonstrated in musical activity, in relation to acculturative stress, the participants were found to experience a positive change. These results imply that the music psychotherapy program offers consistent support through music to North Korean Child Defectors, who are cowering psychologically and experiencing difficulty in adaptation, and reinforces inner resources through their positive self-perception, which indicates that it can be an effective mediation in reducing their acculturative stress.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.3 no.1
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• pp.67-84
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• 1997

Bujeonghangamtang(扶正抗癌湯) has been used for cure of tumor as a traditional medicine without any experimental evidence to support the rational basis for its clinical use. This study was carried out to evaluate the possible therapeutic or antitumoral effects of Bujeonghangamtang extract against tumor, and to carry out some mechanisms responsible for its effect. Some kinds of tumor were induced by the typical application of 3-methylcholanthrene. (MCA) or by the implantation(s.c) of malignant tumor cells such as leukemia cells(3LL cells) or sarcoma cells(Sl80 cells). Treatment of the Bujeonghangamtang water-extract (dailly 1mg／mouse, i. p.) was continued for 7 days prior to tumor induction and after that the treatment was lasted for 20 days. Against squamous cell carcinoma induced by MCA, Bujeonghangamtang decreased not only the frequency of tumor production but also the number and the weight of tumors per tumor bearing mice (TBM). Bujeonghangamtang also significantly suppressed the development of 3LL cell and S180 cell-implanted tumors in occurrence-frequency and their size, and some developed tumors were regressed by the continuous treatment of Bujeonghangamtang extract into TBM. In vitro, treatment of Bujeonghangamtang extract had no effect on the growth of some kinds of cell line such as FsaII, A431 strain but significantly inhibited the proliferation of 3LL, S180 cells and augmented the DNA synthesis of mitogen-activated lymphocytes. Bujeonghangamtang also stimulated the migrative ability of leukocyte, the MIF and IL-2 production of T lymphocytes, but not IL 6 production of B cells. Bujeonghangamtang-administration to mice enhanced NK cells activities. These results demonstrated that Bujeonghangamtang extract exhibited a significant prophylactic benefits against tumors and its antitumor activity was manifested depending on the type of tumor cells. And these results also suggested that effect of Bujeonghangamtang might be chiefly due to nonspecific enhancement of NK cell activities and cell-mediated immune responses.

• The Journal of the Korea Contents Association
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• v.16 no.10
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• pp.546-555
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• 2016

The abuses on the people with disabilities reported through mass media are, in most cases, related to intellectually disabled people, who are vulnerable to abuse. Nevertheless, the actual condition of the abuses on the intellectually disabled people that had remained unrevealed was examined according to socio-demographic variables, social support network, the ability to perform daily activities, and the type of belonging of the handicapped in each age group. Based on these research results, it has been proposed to operate a rest program for their guardians as main caretakers, to improve the education and evaluation programs for activity assistants, and to enhance the quality of integration.

• Journal of Microbiology and Biotechnology
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• v.28 no.5
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• pp.831-838
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• 2018

Trophic interactions of introduced biocontrol fungi with soil animals can be a key determinant in the fungal proliferation and activity. This study investigated the trophic interaction of an introduced biocontrol fungus with soil nematodes. The biocontrol fungus Trichoderma harzianum ThzID1-M3 and the fungivorous nematode Aphelenchoides sp. (10 per gram of soil) were added to nonsterile soil, and microbial populations were monitored for 40 days. Similar results were obtained when the experiment was duplicated. ThzID1-M3 stimulated the population growth of indigenous nematodes (p < 0.05), regardless of whether Aphelenchoides sp. was added. Without ThzID1-M3, indigenous nematodes did not increase in number and the added Aphelenchoides sp. nematodes almost disappeared by day 10. With ThzID1-M3, population growth of nematodes was rapid between 5 and 10 days after treatment. ThzID1-M3 biomass peaked on day 5, dropped at day 10, and then almost disappeared at day 20, which was not influenced by the addition of nematodes. In contrast, a large quantity of ThzID1-M3 hyphae were present in a heat-treated soil in which nematodes were eliminated. Total fungal biomass in all treatments peaked on day 5 and subsequently decreased. Addition of nematodes increased the total fungal biomass (p < 0.05), but ThzID1-M3 addition did not affect the fungal biomass. Hyphae of total fungi when homogenously distributed did not support the nematode population growth; however, hyphae of the introduced fungus did when densely localized. The results suggest that soil fungivorous nematodes are an important constraint on the hyphal proliferation of fungal agents introduced into natural soils.

• Journal of the Korea Computer Industry Society
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• v.4 no.4
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• pp.633-646
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• 2003

Using the self-contained characteristics of XML, in various areas the XML is widely used to a meta language which can describe information and is recognized to a standard language to present information on the web. In this paper, we point out many difficult problems when we are going to a serial activity of software engineering like that we analyze, reuse, and maintenance source programs. Then we describe whether the existed studies about documentation provide the solutions for the problems above mentioned or not. Finally, we propose the JML(Java Markup Language) that can effectively support solutions about these difficulties. Then we analyze the sample program and present the generated JML docuement using the results. explain the result that The JML is an XML DTD to describe software information written by Java language. Also, we describe the meaning of elements that are parts of whole JML, and explain how to represent the information of Java source codes using each element.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.12
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• pp.7060-7067
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• 2014

The reading activity of university students is the key element for the cultivation of creative human resources, and each university develops and performs the various cultural education and library program. Actually, the university libraries check the service periodically through library satisfaction surveys and the library user's actual condition survey to improve it, but the amount of reading, number of books lent and the rate of borrowers are still under expectation. Therefore, in this research, an in-depth analysis of lending books data for freshmen, as the service improvement and revitalization measures of university libraries for students, suggested the following: (1) the early education for the library users, (2) the opening of the students-participating library collections, (3) the use of the data using a library for the consulting with students (4) the establishment of the library depositary for education support, and (5) the introduction of the library CRM for individual student. Through this result, it would be substantially helpful for each university library (including two-year college), in which the number of lending books and the rate of borrowers are below expectations.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.1
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• pp.167-174
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• 2014

Tumor angiogenesis, growth and metastasis are three closely related processes. We therefore investigated the effects of barbigerone on all three in the B16F10 tumor model established in both zebrafish and mouse models, and explored underlying molecular mechanisms. In vitro, barbigerone inhibited B16F10 cell proliferation, survival, migration and invasion and suppressed human umbilical vascular endothelial cell migration, invasion and tube formation in concentration-dependent manners. In the transgenic zebrafish model, treatment with $10{\mu}M$ barbigerone remarkably inhibited angiogenesis and tumor-associated angiogenesis by reducing blood vessel development more than 90%. In vivo, barbigerone significantly suppressed angiogenesis as measured by H and E staining of matrigel plugs and CD31 staining of B16F10 melanoma tumors in C57BL/6 mice. Furthermore, it exhibited highly potent activity at inhibiting tumor growth and metastasis to the lung of B16F10 melanoma cells injected into C57BL/6 mice. Western blotting revealed that barbigerone inhibited phosphorylation of AKT, FAK and MAPK family members, including ERK, JNK, and p38 MAPKs, in B16F10 cells mainly through the MEK3/6/p38 MAPK signaling pathway. These findings suggested for the first time that barbigerone could inhibit tumor-angiogenesis, tumor growth and lung metastasis via downregulation of the MEK3/6/p38 MAPK signaling pathway. The findings support further investigation of barbigerone as a potential anti-cancer drug.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7629-7634
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• 2013

Background: Cylin D1(CCDN1) is an important regulator of the cell cycle whose alterations are thought to be involved in cancer development. There have been many studies indicating CCDN1 amplification or over-expression in a variety of cancer types. In addition to gene amplification, the G870A polymorphism may be related with altered CCDN1 activity, and therefore with cancer development. This hypothesis has been tested in different cancer types but results have been contradictory. We therefore aimed to investigate any relationship between CCDN1 A870G genotypes and laryngeal squamous cell cancer development and progression. Materials and Methods: A total of 68 Turkish patients with primary laryngeal squamous cell cancer and 133 healthy controls were enrolled. Polymerase chain reaction-restriction fragment length polymorphism analysis was used to determine the CCDN1 genotypes. Results: No significant association was detected between CCDN1 genotypes and laryngeal squamous cell cancer (LxSCCa) development. Similarly CCDN1 genotypes were not related to clinical parameters of Lx SCCa. However, there was a very significant association between CCDN1 G allele and presence of perineural invasion (p=0.003; OR: 1.464; CI% 1.073-1.999). CCDN1 G allele frequency was significantly higher in the individuals with perineural invasion (85.7%) when compared to those without (58.5%). The 2 patients who died of disease were both found to possess the GG genotype. Conclusions: These results pose a controversy in suggesting a protective role of the G allele against LxSCCa development and support the association of CCDN1 gene GG genotype with mortality in patients with LxSCCa.