• Clinical and Experimental Reproductive Medicine
• /
• v.29 no.4
• /
• pp.323-335
• /
• 2002

Object: The present study was accomplished to obtain a gene expression profile of the luminal epithelium during embryo apposition in comparison of implantation (1M) and interimplantation (INTER) sites. Material and Method: The mouse uterine luminal epithelium from IM and INTER sites were sampled on day 4.5 (Day of vaginal plug = day 0.5) by Laser Captured Microdissection (LCM). RNA was extracted from LCM captured epithelium, amplified, labeled and hybridized to microarrays. Results from microarray hybridization were analyzed by Significance Analysis of Microarrays (SAM) method. Differential expression of some genes was confirmed by LCM followed by RT-PCR. Results: Comparison of IM and INTER sites by SAM identified 73 genes most highly ranked at IM, while 13 genes at the INTER sites, within the estimated false discovery rate (FDR) of 0.163. Among 73 genes at IM, 20 were EST/unknown function, and the remain 53 were categorized to the structural, cell cycle, gene/protein expression, immune reaction, invasion, metabolism, oxidative stress, and signal transduction. Of the 24 structural genes, 14 were related especially to extracellular matrix and tissue remodeling. Meanwhile, among 13 genes up-regulated at INTER, 8 genes were EST/unknown function, and the rest 5 were related to metabolism, signal transduction, and gene/protein expression. Among these 58 (53+5) genes with known functions, 13 genes (22.4%) were related with $Ca^{2+}$ for their function. Conclusions: Results of the present study suggest that 1) active tissue remodeling is occurring at the IM sites during embryo apposition, 2) the INTER sites are relatively quiescent than IM sites, and 3) the $Ca^{2+}$ may be a crucial for apposition. Search for human homologue of those genes expressed in the mouse luminal epithelium during apposition will help to understand the implantation process and/or implantation failure in humans.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.11 no.1
• /
• pp.70-76
• /
• 2003

Continuous anaerobic hydrogen production with a mixed culture was investigated. With a sucrose concentration of 5g COD/L in the feed, hydrogen production exceeded $0.5mole\;H_2/mole\;hexose$ was found at the early stage, however it did not maintain longer than 9days. It was assumed that the failure was caused by insufficient active hydrogen producing bacteria in the reactor. Therefore, effects of pH control, repeated heat treatment and substrate concentration on sustainable continuous anaerobic hydrogen production was examined to find out operating conditions to sustainable hydrogen production. Decrease of hydrogen production was not overcome by only pH control at 5.3. Repeated heat treatment could recover hydrogen producing activity without any external inoculum supply. However, frequent heat treatment was needed because the treated sludge also showed the tendency in decrease of hydrogen production. With a sucrose concentration of 30g COD/L in the feed, hydrogen production maintained $1.0-1.4mole\;H_2/mole\;hexose$ in continuously stirred tank reactor and $0.2-0.3mole\;H_2/mole\;hexose$ in anaerobic sequencing batch reactor) for 24days. More than 90% of soluble organics in effluent was organic acids, in which n-butyrate was the most one.

• Journal of Radiation Protection and Research
• /
• v.40 no.4
• /
• pp.261-266
• /
• 2015

As performance of electronic personal dosimeter (EPD) used for auxiliary personal dosimeter in nuclear power plants (NPPs) has been being continuously improved, we investigated application cases in Korea and other countries and also tested it in NPPs to assess the performance of EPD for external radiation dosimetry. Result of performance tests done in domestic NPPs was similar to those obtained by IAEA in cooperation with EURADOS (IAEA-TECDOC-1564). In addition, EPD/TLD dose ratio has shown similar tendency of EPD/Film-badge dose ratio from the research by the Japan Atomic Power Company (JAPC) and EPD provided more conservative value than TLD or Film-badge. Although some EPD's failures have been discussed, EPD has shown continuous improvement according to the report of Institute of Nuclear Power Operation (INPO) and data from domestic NPPs. In conclusion, It is considered that the general performance of EPD is adequate for external radiation dosimetry compared with that of TLD, providing appropriate performance checking procedure and alternative measures for functional failure.

• Journal of the Korean Society of Safety
• /
• v.25 no.6
• /
• pp.34-39
• /
• 2010

The purpose of this study is to suggest objective evaluation model as a plan to utilize as opportunity in establishing judgment standard of mutual inspection criteria and to upgrade inspection ability by reviewing and analyzing level of danger and importance in advance based on inspection results of inspection institutions regarding tower cranes used in construction fields. Tower crane is a mechanical device transporting construction supplies and heavy materials to places over 20~150M high from the ground for the period ranging from a short time of 2~3 months to two years after being installed in construction sites in vicinity of buildings or structures and is an important facility indispensable for construction sites. However, since use period after installation is short and professional technical ability of technicians working on-site about of tower crane is poor, systematic and quantitative safety management is not carried out As a part of researches on procedure of RBI(Risk Based Inspection) possible to apply to Knowledge Based System based on knowledge and experiences of experts as well as to tower cranes for solving these problems, quantitative RPN(Risk Priority Number) was applied to RPN utilizing technique of FMEA(Failure Mode and Effect Analyses). When general RBI 80/20 Rule was applied parts with high level of risks were found out as wire rope, hoist up/down safety device, reduction gear, and etc. However, since there are still many insufficient parts as risk analyses of tower crane were not established, it is necessary for experts with sufficient experiences and knowledge to supplement active RBI techniques and continuous researches on tower cranes by sharing and setting up data base of important information with this study as a starting point.

• Journal of Korean Clinical Nursing Research
• /
• v.26 no.2
• /
• pp.198-206
• /
• 2020

Purpose: The rapid response team is a patient safety system that detects symptoms and signs of deteriorating inpatients and provides intervention and treatment. This study analyzed the factors influencing the activation time of the team. Methods: This is a descriptive correlation study that analyzed the electronic medical records of patients activated by the rapid response team. The collection period was from January 2014 to December 2017. We analyzed 278 pieces of data activated by the rapid response team for patients aged 16 years or older at C University S Hospital in Seoul. We employed the SPSS 23.0 program for data analysis. Results: The reasons for activation of the rapid response team were oxygen saturation of less than 90.0%, other causes, and change in consciousness. The most common diagnosis of activated patients was respiratory failure (32.4%). The average activation time was 153.43±286.05 min. The activation time was shortest during convulsions (13.29±7.32 min). For patients with a history of kidney disease (B=0.58, p=.008), in case of surgery (B=0.55, p<.001), if the first symptom is mediated by the physician (B=0.53, p=.007) the active time is often extended. On the other hand, activation time is reduced when consciousness changes (B=-0.51, p=.002), especially when oxygen saturation is below 90.0% (B=-0.64, p<.001). Conclusion: Based on the results of the study, it is expected that patients deteriorating in the general ward would be recognized early, which will help in the effective activation of the rapid response team.

• Korea Journal of Hospital Management
• /
• v.7 no.4
• /
• pp.172-192
• /
• 2002

The purpose of this study is to ascertain whether the effect of introduction of OCS(Order Communication System) to the hospital is satisfied or not comparing the anticipated effect with the actual effect. For this purpose, a domestic hospital which has introduced and has been operating OCS for several years was chosen. Based on the internal data of S Hospital prepared before introducing OCS, researcher has analyzed the basic direction, design standard and status of operation after the introduction of OCS, etc. After analyzing the status of operations of several departments using OCS and interviewing with the chiefs of pertinent departments, a survey form was designed. Actual survey and interviews were conducted by the researcher for weeks to know whether doctors, nurses, medical technicians and clerks of the patient management dept. were satisfied with OCS and to find if they have any recommendations to improve OCS. Based on the analysis of survey, the effect of OCS was evaluated whether it has satisfied the anticipated effectiveness. For the question if they feel convenient in using OCS, doctors, nursing staffs in charge of ward and the staffs of billing dept. has answered that they were all satisfied(100%). The answers for the same question were relatively high in the case of nurses in charge of outpatient and staffs of radiography. Of course, there have been some nurses and staffs who complained for the inconvenience. However, overall satisfaction was high on the average. Some common problems occurred after the introduction of OCS were frequent errors due to instability of OCS system, paralysis of function of hardware on data back-up system and redundant investment due to erroneous choice of DB program in setting DB. It was also pointed out that lack of computer education and low participation of medical staffs has resulted in failure of developing effective software. As a result, it has lowered the efficiency of OCS. For example, some works have to be done by hands even after OCS. Based on the result of this research, recommendations to maximize the effect of OCS were presented as follows. First, strong leadership of CEO and active cooperation of doctors are mandatory. Second, all the process of hospital work should be analyzed and be redesigned in more efficient ways. Third, OCS should be designed to be user-based system which can be used efficiently by all staffs of the hospital. Forth, prior to the operation of OCS, proper tests of the program and trainings of the pertinent staff are required. Fifth, prior to the selection of hardware, BMT(Bench Marking Test) should be conducted. Sixth, before introducing OCS, staffs in charge of OCS should visit many hospitals operating the OCS system and take their cases into account.

• Journal of Elementary Mathematics Education in Korea
• /
• v.23 no.1
• /
• pp.59-74
• /
• 2019

According to previous studies, it shows that the metacognitive ability that makes the positive element of the problem solver positively affects the problem-solving process of mathematics. In order to accurately grasp causality, this study investigates the specific characteristics of the meta-affect factor in the process of problem-solving. To do this, we analyzed the types and frequency of data collected from collaborative problem-solving situations composed of 4th~6th grade mathematically gifted children in small group of two. As a result, it can be seen that the type of meta-affect in the problem-solving process of mathematically gifted children is related to the correctness rate of the problem. First, regardless of the success or failure of the problem-solving, the meta-affect appeared relatively frequently in the meta-affect types in which the cognitive factors related to the context of problem-solving appeared first, and acted as the meta-functional type of the evaluation and attitude. Especially, in the case of successful problem-solving of mathematically gifted children, meta-affect showed a very active function as meta-functional type of evaluation.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.41 no.5
• /
• pp.533-541
• /
• 2021

Retaining walls have been used to prevent slope failure through resistance of earth pressure in railway, road, nuclear power plant, dam, and river infrastructure. To calculate dynamic earth pressure and determine the characteristics for seismic behavior, many researchers have analyzed the nonlinear response of ground and structure based on various numerical analyses (FLAC, PLAXIS, ABAQUS etc). In addition, seismic fragility evaluation is performed to ensure safety against earthquakes for structures. In this study, we used the FLAC2D program to understand the seismic response of the inverted T-type wall with a backfill slope, and evaluated seismic fragility based on relative horizontal displacements of the wall. Nonlinear site response analysis was performed for each site (S2 and S4) using the seven ground motions to calculate various seismic loadings reflecting site characteristics. The numerical model was validated based on other numerical models, experiment results, and generalized formula for dynamic active earth pressure. We also determined the damage state and damage index based on the height of retaining wall, and developed the seismic fragility curves. The damage probabilities of the retaining wall for the S4 site were computed to be larger than those for the S2 site.

• Cross-Cultural Studies
• /
• v.43
• /
• pp.79-113
• /
• 2016

This study aims to diachronically explore the women's movements in modern Japan by focusing on three key words, 'maternity,' 'suffrage,' and 'war,' in uncovering how these concepts relate to Japan as a state. In particular, this study sheds light on the policies toward women not from the perspective of the state, but rather from women's perspective and evaluates their expectations toward the 'state' thorough the activities of Fusae Ichikawa and $Raich{\bar{o}}$ Hiratsuka. Hiratsuka, who was devoted to establishing the 'state protection of maternity,' ended up casting away such expectations toward the state after the failure of the petition movement developed by the New Women's Association. On the other hand, Ichikawa, encouraged by the success of women's suffrage movement in the U.S., remained active in the petition movement in the hope of attaining female suffrage. Because of this, Ichikawa was more vulnerable to the requests by the national authorities for the cooperation in war efforts-event though most of her activities were contained within the redressing of everyday life issues. The expectations toward the 'state' was a principal driving force of women's movements in modern Japan, yet at the same time it was also the reason why-as purging of Ichikawa symbolizes-they came to be stigmatized with the promotion of invasive war.

• The Journal of the Korea Contents Association
• /
• v.19 no.4
• /
• pp.423-431
• /
• 2019

This study examines the effect of the liability limitation provision (LLP) adoption on firm's cost behavior. In April 2011, Korea introduced the LLP with the purpose of improving the management efficiency by mitigating the risks caused by the manager's failure to make decisions related to business operation. However, there are concerns that the adoption of LLP may lead the manager's moral hazard, so the need for empirical research to verify the effect of the LLP adoption is emphasized. In this study, we analyze the effect of the LLP adoption empirically, focusing on the cost behavior that is affected by the manager's decision making. From the empirical result, we find that LLP adopted companies have strengthened the cost stickiness of selling, general, and administrative costs rather than non-adopted companies. This suggests that the manager of LLP adopted company makes a more active decision to consider adjusting costs in order to prepare for future recovery in sales when sales is reduced. This study presents empirical evidence to prove the policy validity of the adoption of LLP, and we expect that our results can contribute to the capital market and academia.