• Applied Biological Chemistry
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• 제46권4호
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• pp.280-284
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• 2003

농업용 살균제와 살충제로서의 활용성 진단과 예측평가 자료로 사용하기 위하여 상용화 된 살균제 133품목과 살충제 152품목의 활성 성분들에 대하여 소수성(LogP), 쌍극자능율(DM), HOMO 및 LUMO 에너지, molar refractivity(MR), polarizability(Pol), van der Waals 분자 표면적 및 부피(Vol), 분자량 및 수화 에너지(hydralion energy) 등, 10 가지의 다양한 물리-화학 파라미터들을 계산하였다. 그리고 살균제와 sterol 생합성 저해제 (DMI: demethylation inhibitor) 및 살충제와 acetylcholine esterase 저해제(AChE)이 가지는 특정한 물리-화학 파라미터들의 범위 값을 설정하였다. 그 결과에 기초하여 다양한 화합물들이 작물 보호제로서 살균제와 살충제로의 활용 가능성이 예측될 것으로 판단되었다.

• Journal of Radiation Protection and Research
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• 제41권3호
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• pp.206-210
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• 2016

Background: Ionizing radiation causes cellular damage and death through the direct damage and/or indirectly the production of ROS, which induces oxidative stress. This study was designed to evaluate the in vivo radioprotective effects of a bio-active material coated fabric (BMCF) against ${\gamma}$-irradiation-induced cellular damage in Sprague-Dawley (SD) rats. Materials and Methods: Healthy male SD rats wore bio-active material coated (concentrations in 10% and 30%) fabric for 7 days after 3 Gy of ${\gamma}$-irradiation. Radioprotective effects were evaluated by performing various biochemical assays including spleen and thymus index, WBC count, hepatic damage marker enzymes [aspartate transaminase (AST) and alanine transaminase (ALT)] in plasma, liver antioxidant enzymes, and mitochondrial activity in muscle. Results and Discussions: Exposure to ${\gamma}$-irradiation resulted in hepatocellular and immune systemic damage. Gamma-irradiation induced decreases in antioxidant enzymes. However, wearing the BMCF-30% decreased significantly AST and ALT activities in plasma. Furthermore, wearing the BMCF-30% increased SOD (superoxide dismutase) and mitochondrial activity. Conclusion: These results suggest that wearing BMCF offers effective radioprotection against ${\gamma}$-irradiation-induced cellular damage in SD rats.

• Nuclear Engineering and Technology
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• 제50권2호
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• pp.313-317
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• 2018

Licenses for the storage of spent nuclear fuel (SNF) and vitrified highly active waste in casks under dry conditions are limited to 40 years and have to be renewed for prolonged storage periods. If such a license renewal has to be expected since as in accordance with the new site selection procedure a final repository for spent fuel in Germany will not be available before the year 2050. For transport and possible unloading and loading in new casks for final storage, the integrity and the maintenance of the geometry of the cask's inventory is essential because the SNF rod cladding and the cladding of the vitrified highly active waste are stipulated as a barrier in the storage concept. For SNF, the cladding integrity is ensured currently by limiting the hoop stress and hoop strain as well as the maximum temperature to certain values for a 40-year storage period. For a prolonged storage period, other cladding degradation mechanisms such as inner and outer oxide layer formation, hydrogen pick up, irradiation damages in cladding material crystal structure, helium production from alpha decay, and long-term fission gas release may become leading effects driving degradation mechanisms that have to be discussed.

• Journal of Advanced Marine Engineering and Technology
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• 제30권1호
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• pp.157-168
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• 2006

Recently, interest in using Al alloys in ship construction instead of fiber-reinforced plastic (FRP) has increased because of the advantages of A) alloy ships over FRP ships, including high speed, increased load capacity. and ease of recycling. This paper investigated the mechanical and electrochemical properties of Al alloys in a slow strain rate test under various potential conditions. These results will provide reference data for ship design by determining the optimum protection potential regarding hydrogen embrittlement and stress corrosion cracking. In general, Al and Al alloys do not corrode on formation of a film that has resistance to corrosion in neutral solutions. In seawater, however, $Cl^-$ ions lead to the formation and destruction of a Passive film. In a potentiostatic experiment. the current density after 1200 sec in the Potential range of $-0.68\~-1.5\;V$ was low. This low current density indicates the protection potential range. Elongation at an applied potential of 0 V was high in this SSRT. However, corrosion protection under these conditions is impossible because the mechanical properties are worse owing to decreased strength resulting from the active dissolution reaction in parallel parts of the specimen. A film composed of $CaCO_3\;and\;Mg(OH)_2$ confers corrosion resistance. However, at potentials below -1.6 V forms non-uniform electrodeposition coating, since there is too little time to form a coating. Therefore, we concluded that the mechanical properties are poor because the effect of hydrogen gas generation exceeds that of electrodeposition. Comparison of the maximum tensile strength, elongation, and time to fracture indicated that the optimum protection potential range was from -1.45 to -0.9 V (SSCE).

• 한국컴퓨터정보학회논문지
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• 제26권11호
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• pp.227-232
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• 2021

「가정폭력범죄의 처벌 등에 관한 특례법」은 아직 법제도 및 시행과정에 여러 문제점들이 존재한다. 법제정의 본래 의도와 다르게 실제 운영에 있어서는 국가의 개입 및 가정폭력 행위자 처벌에 있어서 매우 소극적으로 운영되고 있으며, 가정보호사건으로 처리되는 경우에도 보호처분의 세부내용을 살펴보면 특정 유형의 보호처분에 편중된 보호처분 결정이 내려지고 있는 등 문제점이 있다. 이러한 문제점을 개선하기 위해서는 가정폭력 관련 국가기관간 협력 및 적극적 개입의 필요성이 요구된다. 또한 가정폭력을 신고한 피해자에 대해서 범죄신고자로서 지위를 인정하여 신변보호 요청에 대한 법률적 근거를 마련할 필요가 있다. 그리고 보호처분의 실효성 확보를 위해 보호처분의 불이행이나 위반행위에 대한 제재를 강화할 필요가 있다.

• 대한전자공학회논문지SD
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• 제47권4호
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• pp.75-87
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• 2010

표준 CMOS 공정에서 제작 가능한 보호용 싸이리스터 소자와 다이오드 소자를 사용하는 RF IC용 두 가지 입력 ESD 보호회로 방식을 대상으로, 2차원 소자 시뮬레이터를 이용하는 DC 해석, 혼합모드 과도해석 및 AC 해석을 통해 보호용 소자내 격자온도 상승 및 입력버퍼단의 게이트 산화막 인가전압 측면에서의 HBM ESD 보호강도에 대한 심도있는 비교 분석을 시도한다. 이를 위해, 입력 ESD 보호회로가 장착된 CMOS 칩의 입력 HBM 테스트 상황에 대한 등가회로를 구성하고, 5가지 HBM 테스트 모드에 대해 최대 6개의 보호용 소자를 포함하는 혼합모드 과도 시뮬레이션을 시행하고 그 결과를 분석함으로써 실제 테스트에서 발생할 수 있는 문제점들에 대한 상세한 분석을 시도한다. 이 과정에서 보호용 소자 내 바이폴라 트랜지스터의 트리거를 수월케 하는 방안을 제안하며, 두 가지 보호회로 방식에서 내부회로의 게이트 산화막 파괴는 보호용 소자 내에 존재하는 NMOS 구조의 접합 항복전압에 의해 결정됨을 규명한다. RF IC용 입력 보호회로로서의 두 가지 보호방식의 특성 차이에 대해 설명하는 한편, 각 보호용 소자와 회로의 설계와 관련되는 유용한 기준을 제시한다.

• 한국사회복지학
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• 제65권4호
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• pp.61-88
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• 2013

이 연구는 아동학대 예방과 개입의 큰 축을 담당하는 병원 학대피해아동보호팀의 아동학대 사망사건 개입경험을 탐색할 목적으로 수행되었다. 이를 위하여 전국적으로 등록된 62개 병원 학대피해아동보호팀과 접촉하였고, 최종적으로 아동학대 사망사건을 경험한 5개 병원 학대피해아동보호팀 구성원들(의료사회복지사와 의사)과의 인터뷰를 통해 자료를 수집하였다. 수집된 자료를 질적연구방법을 사용하여 분석한 결과, 팀의 개입에도 불구하고, 학대 피해 아동이 매우 위중한 상태에서 병원에 도착했거나, 보호자의 거짓말이나 치료 거부로 인한 치료적 대응의 지연 때문에, 아동의 사망 진행을 막기 어려웠던 것으로 나타났다. 그럼에도 학대피해아동보호팀의 의심과 개입을 통해 사망 원인이 학대임을 밝혀낸 것은 팀 활동의 의미 있는 성과로 간주되었다. 이 과정에서 신고의무자 역할에 대한 인식 부족과 부담은 의료진의 적극적인 개입을 막는 장애물이며, 개입을 지속하기 위해서는 학대 인과관계 규명에 필요한 증거자료의 확보가 중요하다는 점이 확인되었다. 이러한 연구 결과를 토대로 학대 상황에 대한 조기 발견과 증거 확보 조치, 사망 원인 규명을 위한 실천적 및 정책적 방안에 대해 제언하였다.

• Geomechanics and Engineering
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• 제7권3호
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• pp.263-277
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• 2014

In the conventional design of retaining structures in a seismic zone, seismic inertia forces are commonly assumed to act upwards and towards the wall facing to cause a maximum active thrust or act upwards and towards the backfill to cause a minimum passive resistance. However, under certain circumstances this design approach might underestimate the dynamic active thrust or overestimate the dynamic passive resistance acting on a rigid retaining structure. In this study, a new analytical method for dynamic active and passive forces in c-${\phi}$ soils with an infinite slope was proposed based on the Rankine earth pressure theory and the Mohr-Coulomb yield criterion, to investigate the influence of seismic inertia force directions on the total active and passive forces. Four combinations of seismic acceleration with both vertical (upwards or downwards) and horizontal (towards the wall or backfill) directions, were considered. A series of dimensionless dynamic active and passive force charts were developed to evaluate the key influence factors, such as backfill inclination ${\beta}$, dimensionless cohesion $c/{\gamma}H$, friction angle ${\phi}$, horizontal and vertical seismic coefficients, $k _h$ and $k_v$. A comparative study shows that a combination of downward and towards-the-wall seismic inertia forces causes a maximum active thrust while a combination of upward and towards-the-wall seismic inertia forces causes a minimum passive resistance. This finding is recommended for use in the design of retaining structures in a seismic zone.

• Radiation Oncology Journal
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• 제33권2호
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• pp.66-74
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• 2015

Trace elements play crucial role in the maintenance of genome stability in the cells. Many endogenous defense enzymes are containing trace elements such as superoxide dismutase and metalloproteins. These enzymes are contributing in the detoxification of reactive oxidative species (ROS) induced by ionizing radiation in the cells. Zinc, copper, manganese, and selenium are main trace elements that have protective roles against radiation-induced DNA damages. Trace elements in the free salt forms have protective effect against cell toxicity induced by oxidative stress, metal-complex are more active in the attenuation of ROS particularly through superoxide dismutase mimetic activity. Manganese-complexes in protection of normal cell against radiation without any protective effect on cancer cells are more interesting compounds in this topic. The aim of this paper to review the role of trace elements in protection cells against genotoxicity and side effects induced by ionizing radiation.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 1999년도 춘계종합학술대회
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• pp.330-334
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• 1999

This paper presents a new transient voltage blocking device (TBD) for commucation facilities with low power and high frequency bandwidth. Conventional protection devices have some problems such as low frequency bandwidth, low energy capacity and high remnant voltage. In order to improve these limitations, the new TBD, which consists of a gas tube, avalanche diodes and junction type field effect transistors (JFETs), was designed and fabricated JFETs were used as an active non-linear element and a high speed switching diode with low capacitance limits high current. Therefore the avalanche diodes with low energy capacity are protected from the high current, and the TBD has a very small input capacitance. From the performance test using surge generator, which can produce 1.2/50${\mu}\textrm{s}$ 4.2 k$V_{max}$, 8/20${\mu}\textrm{s}$ 2.1 kA$\sub$max/, it is confirmed that the proposed TBD has an excellent protection performance in tight clamping voltage and limiting current characteristics.