• Title/Summary/Keyword: Activation Properties

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Chemical Properties of Porcine Leukocyte Lysosomal Hydrolases (Porcine Leukocyte Lysosomal Hydrolases의 화학적성질(化學的性質)에 관(關)한 연구(硏究))

  • Cho, Moo-Je
    • Applied Biological Chemistry
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    • v.20 no.2
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    • pp.175-181
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    • 1977
  • Lysosomal enzyme latency was demonstrated for hydrolases from porcine leukocyte by suspending sediment sfrom differential centrifugation in 0.125 to 0.250 M sucrose. Specific activities pH optima and activation energies were determined for hydrolases distributed in various sedimentation fractions and for enzymes solubilized by n-butyl alcohol extraction. Specific activities of the hydrolases revealed the heterogeneity of the Iysosomal fractions relative to enzyme content. pH optima identified the enzyme as acid hydrolases with optima for cathepsin D and aryl sulfatase also at pH 6.8. Activation energies of some hydrolases were low revealing that these enzymes could function efficiently during low temperature aging of meat.

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Neural adaptive equalization of M-ary QAM signals using a new activation function with a multi-saturated output region (새로운 다단계 복소 활성 함수를 이용한 신경회로망에 의한 M-ary QAM 신호의 적응 등화)

  • 유철우;홍대식
    • Journal of the Korean Institute of Telematics and Electronics C
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    • v.35C no.1
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    • pp.42-54
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    • 1998
  • For decreasing intersymbol interference (ISI) due to band-limited channels in digitalcommunication, the uses of equalization techniques are necessary. Among the useful adaptive equalization techniques, because of their ease of implementation and nonlinear capabilites, the neural networks have been used as an alternative for effectively dealing with the channel distortion. In this paepr, a complex-valued multilayer percepron is proposed as a nonlinear adaptive equalizer. After the important properties that a suitable complex-valued activation function must possess are discussed, a new complex-valued activation function is developed for the proposed schemes to deal with M-ary QAM signals of any constellation sizes. It has been further proven that by the nonlinear transformation of the proposed function, the correlation coefficient between the real and imaginary parts of input data decreases when they are jointly Gaussian random variables. Lastly, the effectiveness of the proposed scheme is demonstrated by simulations. The proposed scheme provides, compared with the linear equalizer using the least mean squares (LMS) algorith, an interesting improvement concerning Bit Error Rate (BER) when channel distortions are nonlinear.

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Effect of Zingiber officinale Roscoe Fractionation of Extracts on Mouse Spleen and Macrophage Cells Activation (생강 분획에 따른 추출물이 마우스 비장세포와 Cytokine (IL-1 ${\beta}$, IL-6, TNF-${\alpha}$)의 생성량에 미치는 영향)

  • Ryu, Hye-Sook
    • The Korean Journal of Food And Nutrition
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    • v.20 no.2
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    • pp.125-133
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    • 2007
  • Ginger(Zingiber officinale Roscoe) has long been used as a food source in Korea, and it is widely used as a dietary condiment throughout the world. The present study focused on the immunomodulative effects of ginger extracts via in vitro experiments. To identify the immune-activation fractions of the plant, we performed the systematic fractionation of ginger with methanol, hexane, chloroform, butanol and water for separation and refining. The results showed that the chloroform fraction had the highest immune cell activation properties. In conclusion, this study suggests that ginger extracts may enhance immune function by regulating the splenocyte proliferation as well as the cytokine production capacity of activated macrophages.

Cellular Automata Model of Depolarization Process in Myocardial Cells (심실 세포에서 탈분극 과정의 세포 오토마타 모델)

  • Chang, Yong-Hoon;Jeon, Gye-Rok;Lee, Kwon-Soon;Eom, Sang-Hee;Lee, Sang-Yeol
    • Proceedings of the KOSOMBE Conference
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    • v.1995 no.05
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    • pp.82-86
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    • 1995
  • Using electrocardiography is a common method to diagnose heart disease, Modeling and simulation of activation process for the heart system is useful to understand electrocardiography. This paper proposes a two-dimensional cellular automata model for the activation process of the ventricles. The model represents the geometry of the ventricles by the ellipsoidal shape in two dimension. In the model, ventricles are divided into four layers, each of which has a set of cells with preassigned properties. The proposed model takes Into account the local orientation of the myocardial fibers and their distributed velocity, and refractory period. Simulation experiment is performed to measure activation potential for each cell in each layer within the ventricles.

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Finding of a Characteristic Reactive Region Common to Some Series of Chemical Carcinogens

  • Park, Byung-Kak;Lee, Moon-Hawn;Do, Sung-Tag
    • Bulletin of the Korean Chemical Society
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    • v.6 no.2
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    • pp.103-107
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    • 1985
  • Quantum chemical calculations were carried out to explain how the electronic states of some series compounds vary with metabolic activation. Compounds studied included aromatic amines and amides, polycyclic hydrocarbons, and a few alkylating agents that do not require metabolic activation. The 1, 2 and 4 positions forming the trans-butadiene frame of a molecule, henceforth referred to as "the trans 1, 2, 4 region", have seen to be important positions for the prediction of carcinogenic activity of these compounds. It is also evident that their electrophilic properties increase with metabolic activation. That is the sum of ${\pi}$-electron densities of the trans 1, 2, 4 region in the lowest unoccupied molecular orbital (LUMO) has been found to increase in the order of precarcinogens < proximate-ones < the carbocation ultimate-ones. This is consistent with the fact that chemical carcinogens become more strongly electrophilic with activating. This region not only provides a unified view of structurally diverse carcinogens, but also predicts uniformity in their reactive sites. Accordingly, we suggest that an understanding of the trans 1, 2, 4 region would be helpful in elucidating the mechanism of carcinogenesis.

Study on the Thermal Properties of the Gamma-ray Irradiated EVA/MWCNT Nanocomposites

  • Lee, Kyoung-Yong;Kim, Ki-Yup;Hwang, In-Ra
    • Journal of Radiation Industry
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    • v.3 no.1
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    • pp.31-37
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    • 2009
  • This paper describes the preparation of manufacturing a new nanocomposite material, which involves adding a multi walled carbon nanotube (MWCNT) to improve thermal characteristics of poly (ethylene-co-vinyl acetate) (EVA). We irradiated the prepared nanocomposites with doses of 50 kGy, 100 kGy and 200 kGy at a dose rate of $5kGy\;hr^{-1}$ and examined their thermal stability, activation energy and crosslink level by using a thermogravimetric analyzer (TGA) and gel fraction experiments. TGA results indicated that the samples with a MWCNT had higher Derivative Thermo Gravimetry (DTG) 2nd peak temperatures than those without a MWCNT. And activation energy of the samples reduced as the absorption dose and the MWCNT content increased. Finally, the gel fraction increased rapidly up to 100 kGy as total absorption dose increased, and then the growth rate of all samples was slowly increased from 100 kGy.

Microstructures and Mechanical Properties of Reduced-activation Ferritic/Martensitic (RAFM) Steels with Ti Substituted for Ta (Ta 첨가원소 대체 Ti 첨가형 저방사화 페라이트/마르텐사이트 강의 미세조직과 기계적 특성)

  • Seol, Woo-Kyoung;Lee, Chang-Hoon;Moon, Joonoh;Lee, Tae-Ho;Jang, Jae Hoon;Kang, Namhyun
    • Journal of the Korean Society for Heat Treatment
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    • v.30 no.2
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    • pp.53-60
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    • 2017
  • The aim of this study is to examine a feasibility to substitute Ti for Ta in reduced activation ferritic/martensitic (RAFM) steel by comparing a Ti-added RAFM steel with a conventional Ta-added RAFM steel. The microstructures and mechanical properties of Ta-, and Ti-added RAFM steels were investigated and a relationship between microstructures and mechanical properties was considered based on quantitative analysis of precipitates in two RAFM steels. Ta-, and Ti-added RAFM steels were normalized at $1000{\sim}1040^{\circ}C$ for 30 min and tempered at $750^{\circ}C$ for 2 hr. Both RAFM steels had very similar microstructures, that is, typical tempered martensite with relatively coarse $M_{23}C_6$ carbides at boundaries of grain and lath, and fine MX precipitates inside laths. The MX precipitates were identified as TaC in Ta-added RAFM steel and TiC or (Ti, W)C in Ti-added RAFM steel, respectively. It is believed that these RAFM steels show similar tensile and Charpy impact properties due to similar microstructures. Precipitate hardening and brittle fracture strength calculated with quantitative analysis of precipitates elucidated well the similar behaviors on the tensile and Charpy impact properties of Ta-, and Ti-added RAFM steels.

Distinct properties of tungsten austenitic stainless alloy as a potential nuclear engineering material

  • Salama, E.;Eissa, M.M.;Tageldin, A.S.
    • Nuclear Engineering and Technology
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    • v.51 no.3
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    • pp.784-791
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    • 2019
  • In the present study, a series of tungsten austenitic stainless steel alloys have been developed by interchanging the molybdenum in standard SS316 by tungsten. This was done to minimize the long-life residual activation occurred in molybdenum and nickel after decommissioning of the power plant. The microstructure and mechanical properties of the prepared alloys are determined. For the sake of increasing multifunction property of such series of tungsten-based austenitic stainless steel alloys, gamma shielding properties were studied experimentally by means of NaI(Tl) detector and theoretically calculated by using the XCOM program. Moreover, fast neutrons macroscopic removal cross-section been calculated. The obtained combined mechanical, structural and shielding properties indicated that the modified austenitic stainless steel sample containing 1.79% tungsten and 0.64% molybdenum has preferable properties among all other investigated samples in comparison with the standard SS316. These properties nominate this new composition in several nuclear application domains such as, nuclear shielding domain.

Activation and n-butane adsorption characteristics of palm char (야자각탄의 활성화와 n-butane 흡착특성)

  • 김인기;오한준
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.7 no.1
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    • pp.174-184
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    • 1997
  • Activated carbons were prepared from palm chars by steam activation. The effect of the activation temperature and time, steam concentration and flux on the n -butane adsorption properties were investigated on the basis of surface area, pore analysis and n-butane adsorption. The amount of n -butane adsorption increased with steam concentration and steam flux at higher activation temperature to the $900^{\circ}C$, however this tendancy on the activated carbons were not observed at the temperature above $900^{\circ}C$, It was shown that surface area was 978 $\textrm{m}^2$/g, average pore size was 9.3 $\AA$ and n-butane adsorption was 5.9 g /100ml in the activated carbons, prepared at $900^{\circ}C$, 185 minutes.

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Effect of Pressure and Solvent Dielectric Constant on the Kinetic Constants of Trypsin-Catalyzed Reaction. (Trypsin 반응에 대한 용매의 유전상수 및 압력의 영향)

  • Park, Hyun;Chi, Young-Min
    • Microbiology and Biotechnology Letters
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    • v.28 no.1
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    • pp.26-32
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    • 2000
  • Electrostatic forces contribute to the high degree of enzyme transition state complementarity in enzyme catalyzed reaction and such forces are modified by the solvent through its dielectric constant and polar properties. The contributions of electrostatic interaction to the formation of ES complex and the stabilization of transition state of the trypsin catalyzed reaction were probed by kinetic studied with high pressure and solvent dielectric constant. A good correlation has been observed between the increase of catalytic efficiency of trypsin and the decrease of solvent dielectric constant. Activation volume linearly decreased as the dielectric constant of solvent decreased, which means the increase in the reaction rae. Moreover, the decrease of activation volume by lowering the solvent dielectric constant implies a solvent penetration of the active with and a reduction of electrostatic energy for the formation of dipole of the active site oxyanion hole. When the 야electric constant of the solvents was lowered to 4.7 unit, the loss of activation energy and that of free energy of activation were 2.262 KJ/mol and 3.169 KJ/mol, respectively. The results of this study indicate that the high pressure kinetics combined with solvent effects can provide unique information on enzyme reaction mechanisms, and the controlling the solvent dielectric constant can stabilize the transition state of the trypsin-catalyzed reaction.

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