• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.4
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• pp.78-86
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• 2017

The new businesses started by the companies usually results in being unsuccessful. The main reasons for that are either aiming targeting wrong customers, unsatisfaction of customers' requesting quality standards, or taking wrong actions against the competitors in the market. Therefore, companies should aim the targets for the newly developing products based on the fulfilling values for the customers when they start the new businesses, and should take good cares for risk managements at the each step of the new business to prevent the failure in advance. In addition to that, the companies starting new businesses not only need to take the customers attributes (CA) into account, but they also should apply the new technologies as one system to initiate a new business to satisfy the basic wants of the customers. This article suggests the New Product Development Pursuing Model using the Indicative Planning methodology and the Quality Management tools. The New Product Development Pursuing Model would be completed by the following steps as below; 1. Drawing the CTQ (Critical To Quality) for setting up the new product development objectives by : i) using the VOC (Voice Of Customers) obtained by the QFD (Quality Function Deploypment) if the market is mature, ii) applying AHP (Analytic Hierarchy Process) to information in the QIS (Quality Information System) if the market is unmature to get enough need information of the customers. 2. Risk Management in NPD : The NPD pursuing model consisted of the IP (indicative planning) is suggested not by the process of top-down-way mandatory planning process, but by the tools used in the administrative science and economic fields, namely by governance. The companies could apply innovative methodology for new products development processes to fulfil the customers satisfaction in the fields, through the CA (Contingency Approach) of the NPD (New Product Development) process.

• Journal of the Korean association of regional geographers
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• v.3 no.1
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• pp.99-113
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• 1997

The purpose of this study is to find out about the cause and adaptation process of urban households going to rural areas for agricultural management(Kwihyang nongga) through the microscopic analysis of a case study. Research results are summarized in the followings. The cause of Kwihyang nongga before the 1980s was generally due to the social causes like the support of dependent family or rural-to-urban migrants' maladjustment in urban society. After the 1980s, however, it was related to the economic reasons such as the increase of households' income by commercial agriculture more than the social ones. Most of Kwihyang nongga was traditionally the households which came back to their native places, rural areas. Recently the urban households which did not originally come from rural areas are going to rural space because of the cultivation of high profit oriented agricultural products. Recent Kwihyang nongga increased the size of commercial agriculture through leased farmland, not by a purchase of agricultural land. Even though the number of Kwihyang nongga is now a few, it is expected that the influence of Kwihyang nongga on rural society will be various and high because it consists of young generation. The increase of Kwihyang nongga may be one of the ways to mitigate the decreasing rate of utilization of agricultural lands due to the labor shortage of rural areas after industrialization. To solve rural problems related to underpopulation, it is necessary to establish the active plicies of helping Kwihyang nongga. The actions for Kwihyang nongga ought to emphasize the improvement of educational conditions and living facilities as well as financial aids and the improvement of farming conditions.

• Journal of the Korean association of regional geographers
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• v.8 no.3
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• pp.314-325
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• 2002

The aims of this study is to find the facts of regional inequality and to suggest the desirable location of educational facilities and its related policies through the analysis of the distributional characteristics of high schools in Daegu viewing from public service facilities. The results are as follows. As of 2000 year, there are 76 high schools in operation in Daegu. The number of private high schools is more than that of national public ones in terms of their founders, and the number of general high schools outnumbers that of vocational high schools by their operational types. As a whole, the distribution of schools in Daegu is closely related to the population distribution(redistribution). In case of high schools, it shows that there is severe unevenness between demand and supply of educational facilities per district. The regional inequality of school facilities is getting worse by transfer and new establishment; inter-district transfer is mainly caused by the redistribution of population while intra-district transfer is accelerated by the pressure on better use of land. Recently there is a tendency that schools are newly established by public sector(national public schools) rather than by private sector(private schools). And the predilection or avoidance of a certain area in the process of choosing the site for transfer or new establishment of schools lead to inequality of education opportunities per district. In conclusion, the educational facilities should firstly be placed in the practice of public service facilities in terms of public welfare as well as the convenience of residents and regional inequality. Consequently, both construction of new high schools and the relocation of existing high schools have to be further activated. To achieve them, the role of public actions is particularly more important than that of private ones.

• The Korean Journal of Archival Studies
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• no.41
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• pp.213-260
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• 2014

This paper illustrates the process of Japanese invasion of Joseon. In the December of 1905, specifically, Japan established the Residency-General in order to reform systems of government and to control records. Japan founded the Residency-General to reinforce the internal affairs of Joseon. Then, they reorganized systems of government using Joseon's bureaucracy system. The reorganization facilitated control of current and non-current records. After all, this helped Japan to know the actual circumstances of Joseon and the invasion of Joseon. To be specific, Japan organized the records at the Kyujanggak, an imperial library of the Joseon Dynasty, for understanding historical records and dominated Joseon government's current records for comprehending vulnerability of Joseon. On the other hand, Japan invaded Joseon by justifying their actions as 'administration improvement' and 'reformation'. Here are the actual examples. First, the Residency-General dominated the Kyujanggak and reorganized historical records which were stored there. It lasted for two years and let Japan comprehend the course of Joseon history. Second, the Residency-General collected and arranged current records of Joseon. It was buckled down in the August of 1910, when the Great Han Empire collapsed. After the fall of the Great Han Empire, the Residency-General transferred government records from the Japanese Government-General of Korea in order to understand the state of Joseon. Last, the Residency-General arranged records on both governmental and the Imperial property, then most of them reverted to national property.

• The Korean Journal of Pharmacology
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• v.23 no.2
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• pp.57-75
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• 1987

Two modalities of gonadotropin secretion, pulsatile gonadotropin and preovulatory gonadotropin surge, have been identified in the mammals. Pulsatile gonadotropin secretion is modulated by the pulsatile pattern of GnRH release and complex ovarian steroid feedback actions. The neural mechansim that regulates the pulsatile release of GnRH in the hypothalamus is called "GnRH pulse generator". Ovarian steroids, estradiol and progesterone, appear to exert thier feedback effects both directly on the pituitary to modulate gonadotropin release and on a hypothalamic site to modulate GnRH release; estradiol primarily affects the amplitude while progesterone decreases the frequency of the pulsatile GnRH. Steroid hormones are known to affect catecholamine transmission in brain. MBH-POA is richly innervated by NE systems and close apposition of NE terminals and GnRH cell bodies occurs in the MBH as well as in the POA. NE normally facilitates pulsatile LH release by acting through ${\alpha}-receptor$ mechanism. However, precise nature of facilitative role of NE transmission in maintaining pulsatile LH has not been clearly understood. Close apposition of DA and GnRH terminals in ME might permit DA to influence GnRH release. Action of DA transmission probably is mediated by axo-axonic contacts between GnRH and DA fibers in the ME. Dopamine transmission does not normally regulate pulsatile LH release, but under certain conditions, increased DA transmission inhibit LH pulse. Endogenous opioid acts to suppress the secretion of GnRH into hypophysial portal circulation, thereby inhibiting gonadotropin secretion. However, an interaction between endogenenous opioid peptides and gonadotropin release is a complex one which involves ovarian hormones as well. LH secretion appears to be most suppressed by endogenenous opioids during the luteal phase, at a time of elevated progesterone secretion. The arcuate nucleus contains not only cell bodies for GnRH and ${\beta}-endorphin$ but also a dense aborization of fibers suggesting that GnRH release is changed by the interactions between GnRH and ${\beta}-endorphin$ cell bodies within the arcuate nucleus. The frequency and amplitude of pulsatile LH release seem to be increased during the preovulatory gonadotropin surge. Estradiol exerts positive feedback action on the hypothalamo-pituitary axis to trigger preovulatory LH surge. GnRH is also crucial hormonal stimulus for preovulatory LH surge. It is unlikely, however, that increased secretion of GnRH during the preovulatory gonadotropin surge represents an obligatory neural signal for generation of the LH discharge in primates including human. Modulation of preovulatory LH surge by catecholamines has been studied almost exclusively in rats. NE and E may be involved in distinct way to accumulate GnRH in the MBH and its release into the hypophysial portal system during the critical period for LH surge on proestrus in rats. However, the mechanisms whereby augmented adrenergic transmission may facilitate the formation and accumulation of GnRH in the ME-ARC nerve terminals before the LH surge have not been clearly understood.

• Korean Journal of Health Education and Promotion
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• v.23 no.2
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• pp.63-76
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• 2006

Objectives: The purpose of this study is to find out practicing the health promotion behaviors and the factors relating their health promotion behavior between high school students who live in dormitory and the one who live in their house. Method: This study was carried out by using with questionnaire answered by 1,572 students. Some students are from two academic high schools, and the others are from two girl's high schools in Northern Kyungpook Province from the 27th through 30th of June 2005. Among them, 1,562were included in final analysis. The collected data was analyzed through frequency and percentage, mean and standard deviation, chi-square test, t-test and multiple regression. The data was analyzed using a SPSS/win ver. 12.0. Results: Analysis showed that the total score of practicing health promotion behaviors was 115.1. In case of male students, the score for students in dormitory was 119.6 and the one attending school from house was 114.9(p<0.05). In case of female students, score for students in dormitory was 113.7, and the score for students who live in house was 114.7. According to the data from multiple regression of analysis which has the health promotion behavior practice as a subordinate variable, in male students' case the degree of health promotion behavior practice becomes type of live in a dormitory, high in proportion to their parents' interest in health, disease of student and family, perceived health status, and the perceived self efficacy and the perceived benefit of the health promotion behavior. As to the female students, their health behavior practice becomes level of family economics, high in proportion to their parents' interest in health, perceived health status, and the perceived self efficacy and the perceived benefit of the health promotion behavior. Conclusions: On consideration of above findings, through the systematic development of health education program, we induced to desirable direction for the changeable factors of actions to health promotion for the health. and through the connective guidelines between the school and the home, we have to adapt to effective health promotion program for the health management of the young boys and girls.

• The Korean Journal of Pharmacology
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• v.18 no.1
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• pp.55-63
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• 1982

Lipid peroxidation is the reaction of oxidative deterioration of polyunsaturated lipids and this peroxidation involves the direct reaction of oxygen and lipid to form free radical intermediates, which can lead to autocatalysis. As results of the extensive studies on the lipid peroxidation by many authors, the relationship between lipid peroxidation and the drug metabolizing system as well as the actions of free radicals on the peroxidation was reasonably well known. For a long time, the mechanism of hepatotoxicity of $CCl_4$ was not clearly understood. However, it is now quite well established that $CCl_4$ is activated in vivo to a free radical which is a highly reactive molecule. Therefore, lipid peroxidation which induces the reduction of cytochrome P-450 and aminopyrine demethylase activity is known as decisive event of $CCl_4$ hepatotoxicity. On the other hand, it was also reported that singlet molecular oxygen produces lipid peroxidation in liver microsomes. In this study the effects of benzoyl peroxide on the lipid peroxidation and drug-metabolizing enzyme were examined. Benzoyl peroxide mixed with starch and phosphates etc. is usually used as a food additive for flour bleaching and maturing purpose because of its oxidative property. Albino rats were used for the experimental animals. Benzoyl peroxide was suspended in soybean oil and sesame oil and administered intraperitoneally or orally. TBA value and aminopyrine demethylase activity were determined in liver microsomal fraction and serum. The results were summerized as following. 1) Body weights of animals administered benzoyl peroxide suspension were decreased while that of oil administered group were increased. 2) The activity of aminopyrine demethylase was generally decreased in animals administered oil suspension of benzoyl peroxide. Furthermore, the marked reduction of the enzyme activity was observed in animals administered benzoyl peroxide intraperitoneally. 3) Generally, microsomal TBA values as well as serum TBA were significantly elevated in benzoyl peroxide group in comparison with the control group. However, the more remarkable increase of serum TBA than microsomal TBA was observed in animals administered orally for 6 days. 4) Specifically, the changing pattern of TBA value was notable in serum rather than in liver microsome by intraperitoneal administration of benzoyl peroxide.

• The korean journal of orthodontics
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• v.25 no.6 s.53
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• pp.715-722
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• 1995

Orthodontic tooth movement in response to orthodontic force results from actions of osteoclasts and osteeoblasts in the cell level. Convincing evidence has now been provided to support the view that osteoclasts are derived from mononuclear cells that originate in the bone marrow or other hematopoietic organs and they migrate to the bones via vascular routes. Nitric oxide(NO), which accounts for the biological properties of endothelium-derived relaxing factor(EDRF), is the endogenous stimulator of soluble guanylate cylase. The discovery of the formation of nitric oxide(NO) from L-arginine in mammalian tissues and its biological roles has, in the last 7 years, thrown new light onto many areas of research. Data from experiments in vitro showed that N-metyl-L-arginine(L-NMA) and L-nitro-L- arginine(L-NAME) are competitive inhibitors of nitric oxide synthase. This study suggest that the multinucleated cells in our culture have characteristics of osteoclasts and that the potential bone cell activity of nitric oxide in vitro may be mediated in part by stimulation of marrow mononuclear cells to form osteoclast-like cells. Bone marrow cells were obtaineed from tibia of 19-days old chick embryo. After sacrifice, tibia was quickly dissected and the bone were then split to expose the medullary bone. The cells were attached for 4 hours and the nonadherent cells were collected. Marrow cells weere cultured in 96-well plate in medium 199. To examine the number of TRAP-positive multinucleated cells(MNCs), $10^{-8}\;M\;Vit=D_3$ and various concentration of L-NMA and L-NAME weere added at the beginning of cultures and with each medium change. After 7 days of culture. tartrate-resistant acid phosphatase(TRAP) staining was performed for microscopic evaluation. Cells haying more than three nuclei per cell were counted as MNCs. The obsrved results were as follows;1. 1,25-dihydroxyvitamine $D_3$ stimulated the osteoclast-like multinucleated cells in cultures of chick embryo bone marrow. 2. Nitric oxide synthase inhibitors(NOSI ; N-NMA, N-NAME) stimulated the osteoclast-like cells in cultures of chick embry bone marrow. 3. 1,25-dihydroxyvitamine$D_3$ and nitric oxide synthase inhibitors did not appear to have additive effect on the generation of TRAP-positive MNCs. These results suggest that nitric oxide synthase inhibitors may stimulate the osteoclast-like multinucleated cell formation and fusion in cultures of chick bone marrow.

• Journal of Soil and Groundwater Environment
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• v.8 no.1
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• pp.75-80
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• 2003

Understanding the seawater infiltration into tidal flat sediments is very important, because it is significantly correlated with the supply of dissolved oxygen, nutrients and organic matter to benthic organisms for survival. However oil blocks interstitial spaces of sediments, reduces seawater infiltration and results in the decrease in oxygen, nutrients and other food supply to benthic communities. The penetration depth of the stranded oil into the sediments is one of the most significant information to know the effect of spilled oil on biological communities and to set up a cleaning method. So we initiated this study to quantify the penetration behavior of spilled oil and to evaluate the influence of the penetrated oil on seawater infiltration in tidal flat environment and its ecological implications. The penetration depth of the crude oil into the tidal flat sediments was two times deeper than that of the fuel oil C, and the depth was significantly affected by stranded oil volume. However, the penetration depth of stranded oil was abruptly dropped at first falling tide but not significantly fluctuated after that. Moreover, hydrocarbon concentration showed the highest within the upper 2 cm. Seawater infiltration was decreased in proportion to the stranded oil volume. The seawater infiltration was more affected by the penetrated fuel oil C about 1.7 times than the crude oil, because the interstitial spaces of the top of sediments were more cleared by the fuel oil C. Therefore, quick cleaning actions for penetrated oil will be necessary for recovery of seawater infiltration because the seawater contains oxygen and nutrients necessary for the survival of benthic organisms in tidal flat.

• Journal of Korea Entertainment Industry Association
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• v.14 no.2
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• pp.141-153
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• 2020

The purpose of study is to examine the role of the Professor's friendly behavior as a parameters in the course of Paralanguage Utilization Training using pronunciation, stress, voice tone, speed, pause and expression of feelings affecting of Audiobook text shaping. the results of this study will be a reference to training on the use of Paralanguage for dynamic shaping of Audiobook text and recognizing the need and influence of professors' friendly behavior as a parameters. The results of the study are as follows. First, training in the use of Paralanguage was shown to have a positive effect on the Shaping of Audiobook text and served as a key factor in conveying the original meaning of text. Therefore, if we look at the significance and content of training using Paralanguage and continue training using Paralanguage, it will actually help to shape Audiobook text. Second, the professor's friendly behavior partially acted as a parameters role between training in the use of Paralanguage and shaping Audiobook text. The professor's friendly behavior has helped form Audiobook text by providing a sense of trust and will increase the level of completion for training in the use of Paralanguage. Thus, training in the use of Paralanguage Utilization Training could result in more effective Audiobook text shaping when conducted in conjunction with the professors' friendly actions. Therefore, it was shown that the ability to use Paralanguage and the professor's caring and friendly behavior to help them perform better were more effective when they simultaneously affected Audiobook text shaping.