• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2004년도 Annual Meeting and International Symposium
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• pp.185-197
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• 2004

Type 2 diabetes is characterized by hyperglycemia and hyperinsulinemia, features of insulin resistance. In vivo treatment of ob/ob mice with hydrolyzed fibroin reverses these pathological attributes (6). To explore the mechanism underlying this effect, we have used the 3T3-Ll adipocytes as a cell type which would represent the periphery, in vivo. Exposure of 3T3-Ll adipocytes to chronic insulin leads to the a 50% loss of insulin-stimulated glucose uptake. Chronic exposure to fibroin blocked, in part, the response to chronic insulin but also increased the sensitivity of control cells to the acute action of insulin. The later effect was most robust at physiological concentrations of insulin. Fibroin did not prevent the insulin-induced down-regulation of the insulin receptor or the tyrosine kinase activity associated with the receptor. Further, fibroin had no affect on the loss in activity of the insulin-sensitive down-stream kinase, Akt. Interestingly, fibroin accelerated glucose metabolism and glycogen turnover independent of insulin action. In addition, fibroin up-regulated GLUT1 which increased its expression at the cell surface and caused the redistribution of GLUT4 to the plasma membrane. Together, these later effects would lead to an improvement in hyperglycemia in vivo which would in turn reduce the need for insulin.

• 공학교육연구
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• 제27권1호
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• pp.50-62
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• 2024

This study examined how emotion regulation strategies specifically function in the interpersonal conflict coping strategies of engineering students. For this purpose, a interpersonal conflict coping strategies and emotion regulation strategies scale was used for 548 engineering students. Multiple regression analysis was conducted. Among the emotion regulation strategies, the "return to body" strategy was related to understanding, validation, focusing, and the "stop action" strategy. In particular, the "stop action" strategy was closely related only to the "return to body" strategy. Among interpersonal conflict coping strategies, the dominating strategy used both positive emotion regulation strategies, such as high refocus on planning, and negative emotion regulation strategies, such as other-blame. Additionally, among negative conflict coping strategies, it was confirmed that both aggression and negative emotional expression, which seem to have similar attributes, share a common feature of having high difficulty in emotional clarity. However, in the case of negative emotional expression, it is characterized by a lack of putting into perspective and high other-blame. On the other hand, the agression strategy seemed to have different characteristics, such as high self-blame and low return to body. By investigating the relationship between interpersonal conflict coping strategies and specific emotion regulation strategies, this study provides implications for education and intervention on which specific emotion regulation strategies need to be cultivated for engineering students to improve their interpersonal conflict resolution capabilities.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제6권1호
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• pp.58-67
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• 2000

엔터프라이즈 네트웍의 크기가 커지고 그 관리 범위가 넓어짐에 따라 분산 망 관리 시스템의 수용을 요구하게 되었고 또한 표준 프레임웍들간의 상호 연결 및 작용이 필요하게 되었다. 이 논문에서는 네트웍 관리 프레임웍인 SNMP도메인과 분산 객체 기술의 하나인 CORBA도메인간의 통합 관리를 위한 구현 방안을 제시한다. 표준에서 사용하는 직접 변환은 객체 지향적인 특성을 표현하고 있지 않으며, action을 위한 속성의 정의가 다른 속성과 구별되지 않는 등의 한계를 지니고 있다. 이러한 한계점은 추상적 변환 방법을 통해 새로운 클래스의 정의, 명확한 메쏘드 정의라는 방법으로 충분히 극복될 수 있다. 직접 변환의 편리함과 추상적 변환의 효율적인 관리 정보의 구축이라는 장점을 이용한 직접 변환과 추상적 변환의 혼용을 통한 정보 모델 변환 방법을 이용한 게이트웨이의 개발 방법을 제시한다. 이러한 통합 관리 시스템 구축은 CORBA/SNMP 간의 효율적인 통합 관리를 제공한다.

• 미술이론과 현장
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• 제15호
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• pp.83-109
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• 2013

The study mainly discusses appreciation of interactive art works seen from the perspective of play attributes that make spectators glimpse the truth of things. The general studies of interactivity, as one of remarkable features in contemporary art, are regarding the relation between the effects of digital media and interactivity as well as video games. From the preceding discussion, I analyze the effects of the appreciating interactive art works which are focused on new sensory systems, the methods to intuit the essence of the art works. Based on the concept, as I investigate the play attributes found in the interactive art works, this study gives attention to the possibility that if the spectators can reach the inherent aspects of interactive art works, while interacting them. Thus to discuss the properties of the play, this article studies play concept of Johan Huizinga(1872-1945), psychologist and anthropologist and play theory of Hans Georg Gadamer(1900-2002) who considers play as a metaphor for art. As Huizinga thinks acting is the important attribute of play, Gadamer argues whenever the term 'play' is used, we should think about 'to-and tro movement' and the movement is absence of goal as well as endlessly renews through repetition. Then what we should pay attention to, seeing the essence of art and play as similar? That is, Gadamer claims, we can understand the truth of things through the play. To apply the play concept to the interactive art works, I research the works of Maurice Benayoun(1957 - ), French interactive artist. By employing interactivity, he attempts to extend and affect the experience of his art works to one of social phenomenon. Striving this, spectators can widen and deepen the breadth of their intuition and recognize the essence of art works. It is the interactive art works that can be the apex of the transformation of structure from the play to the art. The endless repetitive process of play, which is free creation-annihilation process, is similar with the interactive experience of spectators that is variable, de-centered, and multi-sensory. The pure action of the play lets us recognize, sense and accept the world and through the system of interactive art experience, we can expand the horizons of perception. Interactive art works with these play attributes are capable of playing the role that the spectators glimpse the truth of things and experience the world around them.

• 농업과학연구
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• 제21권2호
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• pp.92-102
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• 1994

This study examined Public Evaluation for functions of urban open space environment using a marketing strategy called Importance-Performance analysis. 12 main function attributes for urban open space environment were selected 150 respondents were sampled in Taejon city by personal interview. Ratings used mean values from a seven-point scale. Results were then graphically displayed on an easily interpreted two-dimensional 'Action Grid'. Generally Importance Ratings were high, but Performance Ratings were low relatively for various open space environment functions. In air pollution control function the difference was the most large. The results of rating scale analysis indicated repondents' sexual and residence period difference.

• ETRI Journal
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• 제43권6호
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• pp.1004-1012
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• 2021

The collaboration productively interacting between multi-agents has become an emerging issue in real-world applications. In reinforcement learning, multi-agent environments present challenges beyond tractable issues in single-agent settings. This collaborative environment has the following highly complex attributes: sparse rewards for task completion, limited communications between each other, and only partial observations. In particular, adjustments in an agent's action policy result in a nonstationary environment from the other agent's perspective, which causes high variance in the learned policies and prevents the direct use of reinforcement learning approaches. Unexpected social loafing caused by high dispersion makes it difficult for all agents to succeed in collaborative tasks. Therefore, we address a paradox caused by the social loafing to significantly reduce total returns after a certain timestep of multi-agent reinforcement learning. We further demonstrate that the collaborative paradox in multi-agent environments can be avoided by our proposed effective early stop method leveraging a metric for social loafing.

• 대한약리학회지
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• 제32권3호
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• pp.373-380
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• 1996

최근 본 연구실에서는 GS 386인 1-(4'-methoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinoline이 적출된 토끼의 심방세포에서 $Ca^{++}$ 채널의 운동성 변화없이 $Ca^{++}$ 채널이 열릴 가능성을 줄임으로써 $Ca^{++}$ 전류의 증폭을 억제한다고 보고하였다. 이번 연구에서는 적출된 쥐의 기관지를 사용하여 GS 386의 작용기전에 대해 연구하였다. GS386은 carbachol $(0.3{\mu}M)$과 높은 농도의 $K^+$ (65.4mM)에 의해 수축된 쥐의 기관지를 용량-의존적으로 이완시켰으며 이때 $IC_{50}$는 5.24와 $5.67\;{\mu}M$이었다. verapamil은 carbachol에 의한 수축시 보다 높은 농도의 $K^+$에 의해 수축된 조직에 더욱 효과적으로 억제하였다. $Ca^{++}$이 없는 상태에서 $Ca^{++}$에 의한 수축은 GS386에 의해 억제되었다. 더욱이 높은 농도의 GS386$(100\;{\mu}M)$은 verapamil과는 다르게 carbachol뿐만 아니라 caffeine에 의한 위상성 수축을 억제 시키므로 GS386은 세포질내로 들어가 sarcoplasmic retuculum과 같은 근육 내부에 2차적인 영향을 나타내었다. 더군다나GS386은 verapamil에 의해 영향을 받지않는 (verapamil-insensitive component)이완을 보였고 쥐 기관지의 평활근에서 cAMP의 양을 증가 시켰다. 이러한 결과는 GS386의 작용기전이 $Ca^{++}$ 길항적인 작용 뿐만 아니라 posphodiesterase억제작용에 기인한다는 사실을 제시한다.

• 한국콘텐츠학회논문지
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• 제10권5호
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• pp.152-164
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• 2010

현대에 주요하게 부각되고 있는 상호작용 공간을 효과적으로 디자인하기 위해서는 상호작용성 영향요인들을 이해하고 이를 수용하는 사용자 중심적인 공간디자인 방법론이 필요하다. 본고는 이를 위한 기반을 마련하고자 하였으며 이 연구주제로 수행될 3편의 연계논문 중 첫번째 연구이다. 디자인의 기본 관련영역을 기반으로 설정한 분석지표(시스템영역, 사용자영역, 관계영역)에 의거하여 상호작용성 영향요인에 대해 분석한 결과, 상호작용성의 첫번째 영향요인은 상호작용성을 위한 접속의 장인 인터페이스로 분석되었다. 이의 세부유형 분석은 연계연구 II 편의 연구과제이다. 두번째 영향요인은 상호작용성의 발생 주체인 인터서브젝트이다. 이의 세부유형은 사용자의 상호작용 욕구의 측면에서 파악되어 기능적 & 조형적욕구, 외현 & 잠재 욕구, 정보커뮤니케이션 & 공감 욕구의 6개 세부유형이 분석되었다. 세번째 영향요인은 상호작용성의 실제 수행과정인 인터랙션이다. 이의 세부유형은 상호작용 행태 프로세스의 측면에서 파악되었고 접속, 몰입, 심성모형 형성, 상호작용 행위, 변형, 경험적 발생의 여섯 단계로 분석되었다.

• 한국산업정보학회논문지
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• 제15권2호
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• pp.127-137
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• 2010

Widget은 Web 2.0 및 모바일 컨버젼스 패러다임을 주도하는 차세대 지능형 플랫폼으로 평가 받고 있다. 향후 이러한 widget의 발전을 예상할 때, 현재 사용자들의 인식에 대한 분석은 앞으로 widget의 방향성을 결정하는데 무엇보다 필요할 것이다. 따라서 본 연구의 목적은 widget의 사용에 영향을 주는 인터페이스 요인을 규명하여 인터페이스 요인에 따른 widget의 사용의도를 설명함으로써 widget 활성화를 위한 전략적 방안을 모색하는 것이다. 분석 결과 일관성, 직관성, 최소한의 조작, 개인화가 인지된 용이성에 정의 영향을 주며, 개인화와 시각적 매력은 인지된 즐거움에 영향을 줌을 확인하였다. 또한 인지된 용이성은 인지된 즐거움에 영향을 주며, 인지된 즐거움은 사용의도에 직접적인 영향을 주었다. 그러나 인지된 용이성이 사용의도에 직접적인 영향을 준다는 가설은 기각되었다.

• 한국축산식품학회지
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• 제43권6호
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• pp.1087-1110
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• 2023

The growing demand for sustainable food production and the rising consumer preference for fresh, healthy, and safe food products have been driving the need for innovative methods for processing and preserving food. In the meat industry, this demand has led to the development of new interventions aimed at extending the shelf life of meats and its products while maintaining their quality and nutritional value. Cold plasma has recently emerged as a subject of great interest in the meat industry due to its potential to enhance the microbiological safety of meat and its products. This review discusses the latest research on the possible application of cold plasma in the meat processing industry, considering its effects on various quality attributes and its potential for meat preservation and enhancement. In this regard, many studies have reported substantial antimicrobial efficacy of cold plasma technology in beef, pork, lamb and chicken, and their products with negligible changes in their physicochemical attributes. Further, the application of cold plasma in meat processing has shown promising results as a potential novel curing agent for cured meat products. Understanding the mechanisms of action and the interactions between cold plasma and food ingredients is crucial for further exploring the potential of this technology in the meat industry, ultimately leading to the development of safe and high-quality meat products using cold plasma technology.