• Journal of Periodontal and Implant Science
• /
• v.25 no.3
• /
• pp.635-647
• /
• 1995

Human polymorphonuclear leukocytes(PMN) constitute a first line of defense against all forms of injury and microbial challenge, which share a common cell lineage with macrophage. Microbial component LPS activates macrophages to produce IL-1, MIP-1${\alpha}$, -1${\beta}$, TNF-${\alpha}$ and IL-6, etc. Those cytokines have autocrine function to the macrophages, and paracrine function to other cell such as PMN and affect them to produce some biological functions. Having a responsive homogeneous cell line, HL-60, offers us the possibility of studying extensively on the function of PMN, which were not possible previously with peripheral PMN, due to the short-lived nature and difficulty of getting a purified PMN. In the present study, I performed MIP-1 receptor binding assay using HL-60 cell and human peripheral PMN. Also, in vitro antimicrobial assay was performed using differentiated or undifferentiated HL-60 cell. Differentiation was induced by treatment with 500 M of $N^6,O^2-dibutyryl$ adenosine 3'5' cyclic monophosphate(dbcAMP) (PMN-like cell), or 20ng/ml of 12-O-tetradecanoylphorbol-13-acetate(TPA) (macrophage/monocyte-like cell). Receptors for MIP-1${\alpha}$ were identified on dbcAMP-treated HL-60 as well as peripheral PMN. However, bound radioactive MIP-1${\alpha}$ on differentiated HL-60 was much higher than that of peripheral PMN, which suggest receptor number of differentiated HL-60 cell is higher than that of peripheral PMN. Although both of TPA and dbcAMP treatment significantly enhanced antimicrobial action of HL-60 cell, dbcAMP-treated cell(PMN-like HL-60) killed S.aureus more effectively in this experiment. TPA or dbcAMP treatment significantly enhanced antimicrobial action of undifferentiated HL-60 cell. MIP-1${\alpha}$ further increased enhancing effect of TPA or dbcAMP. IL-1${\alpha}$, however, increased only dbcAMP-induced enhancing effect of antimicrobial action of HL-60 cell. These results suggest that differentiated HL-60 cell could replace peripheral PMN in analysis of various biological functions of cytokines on PMN cell.

• Proceedings of the KIEE Conference
• /
• summer
• /
• pp.590-593
• /
• 2004

This paper presents recent trends on the on-line monitoring and diagnostic systems for oil-immersed transformers. Specially, our system on YeoSu thermal power plant is introduced for high sensitivity and accuracy of ours. It is combined with communication networks to provide an on-line remote monitoring system. Several alarm criteria are formulated to enable a superimposed monitoring system to perform decisive action. The reasons for monitoring the condition and maintaining the health of electrical apparatus were discussed. The experience at the fields and the criteria for the judgment are also discussed in detail.

• Proceedings of the KIEE Conference
• /
• 2003.07c
• /
• pp.1644-1646
• /
• 2003

This paper presents recent studies on the on-line insulation monitoring and diagnostic systems for transformers developed by HHI. Sufficiently high sensitivity and accuracy for practical use were achieved for the system, combined with communication networks to provide an on-line remote monitoring system. Several alarm criteria are formulated to enable a superimposed monitoring system to perform decisive action. The reasons for monitoring the condition and maintaining the health of electrical apparatus were discussed. The experience at the fields and the criteria for the judgment are also discussed in detail.

• Journal of the Korean Society of Clothing and Textiles
• /
• v.26 no.3_4
• /
• pp.539-547
• /
• 2002

Heungdukwang's(興德王) costume ordinance(834A.D.) is a very important written historical record because it reveals Tongil Shilla's(統-新羅) costume. And among the clothing pieces that appeared in Heungdukwang's(興德王) costume ordinance, from Pyosang(表裳), Naesang(內裳), we know they wore one skirt over another. But skirts appearing in visual records are wort in waist line or breast line, and when they wore skirts in breast line, there were shoulder belts or not. Also among the clothing pieces that appeared in Heungdukwang'a (興德王) costume ordinance, Yo( ) and Ban( ) seems to be connected with skirt. but it is not clear. So this study focuses on the history of wearing skirt in breast line and one skirt over another, shoulder belts of skirt, and relation among yo( ), Ban( ) and skirt. The results are as follows. First, wearing skirt in breast line is already appeared in Ancient Shilla's(新羅) clay figure, and wearing one skirt over another is also appeared in Sunhung tomb's mural painting. so it is not completely under the influence of Tang(唐). Second, the shoulder belts of skirt is for convenience of action, But, at that time, there is no shoulder belts of skirt in Tang(唐). Third, between Yo( ) and Ban( ), If Yo( ) is connected with skirt, it is a shoulder belts of skirt or waist of skirt. And Ban( ) is a ire of skirt.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.42 no.3 s.303
• /
• pp.17-28
• /
• 2005

Recently intelligent characters in computer games have been an important element more and more because they continually stimulate gamers' interests. As a typical method for implementing such intelligent characters, neural networks have been used for training action patterns of opponent's characters and game rules. However, some of the game rules can be abruptly changed and action properties of garners in on-line game environments are quite different according to gamers. In this paper, we address how a neural network adapts to those environmental changes. Our adaptation solution includes two components: an individual adaptation mechanism and a group adaptation mechanism. With the individual adaptation algorithm, an intelligent character steadily checks its game score, assesses the environmental change with taking into consideration of the lastly earned scores, and initiates a new learning process when a change is detected. In multi-user games, including massively multiple on-line games, intelligent characters confront diverse opponents that have various action patterns and strategies depending on the gamers controlling the opponents. The group adaptation algorithm controls the birth of intelligent characters to conserve an equilibrium state of a game world by using a genetic algorithm. To show the performance of the proposed schemes, we implement a simple fighting action game and experiment on it with changing game rules and opponent characters' action patterns. The experimental results show that the proposed algorithms are able to make intelligent characters adapt themselves to the change.

• The KIPS Transactions:PartB
• /
• v.13B no.4 s.107
• /
• pp.449-456
• /
• 2006

This paper proposes intelligent characters for fighting action games to which energy points are applied for more realistic implementation than those of previous researches. The intelligent characters decide their actions in consideration of their energy level as well as a current action, the step of the action, the distance, and past actions of opponent characters that were used in existing intelligent ones. We used two types of energy, HP(Health Point) and MP(Mana Point) that were frequently employed in recent on-line games. We experimented with proposed intelligent characters to investigate whether the intelligent characters learn proper actions and cope with opponent characters in consideration of their energy levels. Experimental results showed that the intelligent characters reacted with the best actions to obtain high score if their energy is sufficient, Otherwise, they did the actions to(that?) recharge their energy. From this observation, we could conclude that the proposed intelligent characters worked well and did effective actions in consideration of the their energy.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.63 no.9
• /
• pp.1171-1179
• /
• 2014

ISO(Independent System Operator) or TSO(Transmission System Operator) use power system analysis program to simulate contingency analysis and remedial actions to operate power system stably. Generally, power system analysis program provides automated analysis functions(or modules) to deal with wide area power system. However, because of missed contingency cases, automated contingency analysis has no practical use or has limitation. And in case of remedial action, it doesn't support automated function or takes a lot of times to study, because of simulation in manual for each cases. This paper suggests that new relation with buses and transmission line properties of power system DB used for power system analysis program to simulate automated contingency including all contingency cases needed in the field without missed cases. And it proposes automated remedial action scheme based on practical approach analysis to alleviate overloading or voltage problems. Finally it deals with automated contingency/remedial action analysis(automated scheduled outage) program which is developed by KEPCO and its performance and proposed schemes are proven by case study for real Korean power system data.

• Journal of the Korea Computer Industry Society
• /
• v.7 no.3
• /
• pp.163-170
• /
• 2006

This paper proposes intelligent characters for fighting action games to which energy concepts are applied for more realistic implementation than those of previous researches. The intelligent characters decide their actions in consideration of their energy level as well as a current action, the step of the action, the distance, and past actions of opponent characters that were used in existing intelligent ones. We used two types of energy, HP(Health Point) and MP(Mana Point), that were frequently employed in recent on-line games. We experimented with proposed intelligent characters to investigate whether the intelligent characters loam proper actions and cope with opponent characters in consideration of their energy levels. Experimental results showed that the intelligent characters reacted to the best actions to obtain high score if their energy is sufficient, otherwise they did the actions to recharge their energy. From this observation, we could conclude that the proposed intelligent characters worked well and did effective actions in consideration to the their energy.

• Journal of Drive and Control
• /
• v.15 no.4
• /
• pp.1-10
• /
• 2018

Spool displacement of a direction control valve is the standard signal to measure the bandwidth frequency of the direction control valve. When the spool displacement signal is not available, it is suggested in this study to use the metering hydraulic line as an alternative way to measure - 90 degree phase bandwidth frequency of the hydraulic direction control valve. Dynamics of the hydraulic line is composed of inertia, capacitance, and friction effects. The effect of oil inertia is dominant in common hydraulic line dynamics and the line dynamics is close to a derivative action in a range of high frequency; such as a range of bandwidth frequency of common directional control valves. Phase difference between spool displacement and line load pressure is nearly constant as a valve close to 90 degree. If phase difference is compensated from the phase between valve input and pressure, compensated phase may be almost same as the phase of spool displacement that is a standard signal to measure phase bandwidth frequency of the directional control valve. A series of experiments were conducted to examine the possibility of using line pressure in to measure phase bandwidth frequency of a directional control valve. Phase bandwidth frequency could be measured with relatively high precision based on metering hydraulic line technique and it reveals consistent results even when valve input, oil temperature, and supply pressure change.

• YAKHAK HOEJI
• /
• v.49 no.5
• /
• pp.422-427
• /
• 2005

Our previous data showed the protein isolated from Coptidis Rhizoma (CRP) had antifungal activity. In present study, we examined mode of action of the CRP and its activity against subcutaneous candidiasis due to C. albicans yeast cells. Results showed that the CRP blocked hyphal production from yeast form of C. albicans. The CRP also activated RAW 264.7 monocyte/macrophage cell line, which resulted in nitiric oxide (NO) production from the cells. This activation seemed to increase macrophage phagocytosis to destroy the invaders. Like other antimicrobial peptides, CRP was influenced by ionic strength, thus resulting in a decrease of antifungal activity. In murine model of a subcutaneous candidiasis, the sizes of infected areas of the nude mice given the CRP after subcutaneous injection of C. albicans yeast cells to the dorsal skin were $90\%$ less than those of the nude mice groups that received DPBS instead of the CRP. All data indicate that the CRP, which appeared to act like an antimicrobial peptide and to inhibit the morphological transition from blastoconidia, was effec­tive against the subcutaneous disease.