• Natural Product Sciences
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• 제17권1호
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• pp.38-44
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• 2011

The quality inspections items such as loss on drying, total ash, and acid-insoluble ash contents in herbal medicines, have a correlation with external sources of pollution, but are not themselves hazardous factors. Z-scores for standard normal distribution were used to investigate herbal medicines requiring quality control, which exceeds the regulatory limits of quality inspection. In total, 7,773 samples were analyzed based on plant parts. For the loss on drying, the numbers of items of herbal medicines requiring quality control are like these; 15 items for above-ground parts and 5 items for underground parts. For the total ash, 21 items for above-ground parts and 4 items for underground parts. For the acid-insoluble ash, 8 items for above-ground parts and 1 item for underground parts.

• 약학회지
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• 제53권5호
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• pp.274-280
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• 2009

To survey the status of quality control of major ingredients of 'Ssanghwatang (Oriental medicine used for fatigue)', we analyzed 1,024 samples (9 kinds) of medical herbs to determine amounts of ashes, acid-insoluble ashes, loss on drying that are major elements to ensure basic quality of herbal drugstuffs. After ash analysis, Paeoniae Radix (from China) failed to meet the herbal standard criterion. After yielding Z-score(indicating the probability of exceeding its criterion) Zizyphi Fructus, Zingiberis Rhizoma, Paeoniae Radix, Rehmanniae Radix Preparata became objects of intense quality control (=IQC). Analysis on loss on drying shows Cinnamomi Cortex was unsuitable and was put under the IQC. In case of respective heavy metals, Angelicae Gigantis Radix, Cnidii Rhizoma, Cinnamomi Cortex exceeded the maximum permissible range for Cd. The 3 kinds of sub-standards were put to the IQC. Statistic figures showed a significant correlation (t-test, p<0.01) between country-of-origin and sub-quality rates. Compared to domestic one, imported medicinal herbs were less suitable in regard of acid-insoluble ash, loss on drying and Pb/Hg content. Meanwhile, amounts of Acid-insoluble ash showed positive relation with amounts of Pb (r=0.202) and As (r=0.243) among heavy metals leading to an inference that herbs of which root/rhizome is used for medical purposes attribute its high heavy metal content to the fine earth/sand being stuck to its root stalk.

• 분석과학
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• 제27권2호
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• pp.114-120
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• 2014

한약재의 약용부위에 따른 회분, 산불용성회분 및 중금속의 함량을 조사하였다. 시료는 서울지역에서 유통되는 1504건(84품목)의 한약재를 포장단위로 구매하였고, 약용부위에 따라 5종류로 분류하였다. 회분, 산불용성회분의 평균함량(%)은 잎 9.0, 1.1, 줄기표피 6.1, 1.0, 꽃과실씨 5.1, 0.8, 뿌리 4.6, 0.7, 뿌리줄기 4.3, 0.4이었고, 개별중금속(납, 비소, 카드뮴, 수은)의 함량(mg/kg)을 더한 수치의 평균은 잎 1.13 > 줄기표피 1.07 > 뿌리줄기 0.91, 뿌리 0.91 > 꽃과실씨 0.73이었다(p<0.05). 그리고, 전체시료에서 산불용성회분과 개별중금속들의 합은 상관관계(r=0.314)가 있었다(p<0.01).

• 생약학회지
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• 제50권4호
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• pp.312-317
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• 2019

In order to obtain basic data on the shelf life of Epimedii Herba (EH), a physicochemical characteristics including weight loss rate, loss on drying, ash, acid-insoluble ash, and quantitative determination were evaluated to compare the data by packaging methods including general (G), general + silica gel (GS), alumium (AL), and alumium + silica gel (ALS) packaging and storage periods (0-66 months). All physicochemical analyzes were conducted using the method of "The Korean Pharmacopoeia (KP) 9^th edition". As a result, weight loss rate (%), loss on drying (%), ash (%), acid-insoluble ash (%) of EH according to the packaging methods and storage periods were -0.27-4.73%, 3.06-9.35%, 5.48-7.37%, and 0.45-0.99, respectively. In the quantitative analysis of icariin, the marker compound of EH using high-performance liquid chromatography, the initial content was 0.44% at 0 month in all packaging methods. After that, the result of analyzing the content of icariin every 6 months was detected 0.44-1.18%. All of the above results satisfied the acceptance criteria for loss on drying, ash, acid-insoluble ash, and quantification contained in the KP. This study can be used as a basic data for establishing the packaging method and shelf life of EH.

• 한국연초학회지
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• 제10권2호
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• pp.99-107
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• 1988

Pot experiment was conducted to find out the effect of lime application on yield and chemical composition of burley tobacco in 1986, Lime increased exchangeable calcium and pH of soil, but decreased Al, Fe and Mn concentrations. Yield was increased by lime application, however lime could not be caused to yield increasing in the soil with high calcium contents. Cored leaves of limed Plot contained higher Mg. K, total nitrogen, NO3-nitrogen, water soluble and insoluble ash, alkalinity number of water soluble and insoluble ash, citric and malic acid, but lower Fe, Mn, protein-nitrogen, NH3-nitrogen, nicotine petroleum ether extract, palmitic and linolenic acid concentrations than those of unlined plot. The linoleic acid and volatile neutral constituents of cured leaves were not affected by liming. Lime increased yield, however it did not affect leaf duality in respect to chemical characteristics, suggesting that liming should be necessary for tobacco cultivation.

• 한국식품과학회지
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• 제5권2호
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• pp.113-118
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• 1973

한국산의 참깨를 탈피(脫皮) 한 것과 탈피(脫皮) 하지 않은것, 이들을 각각 채유(採油)한 기름 및 박(粕)에 대하여 일반성분, 기름의 성상(性狀), 지방 조성, 아미노산 조성, 특수 미량성분 및 oxalate 의 함량 들을 비교 분석한 결과 다음과 같은 결론을 얻었다. 1) 탈피(脫皮)참깨 및 그 박(粕)은 탈피(脫皮)하지 않은 전(全)참깨 및 박(粕)보다 조섬유, 조회분, 산불용성회분의 함량이 더 적었다. 2) 탈피(脫皮)참깨기름은 전(全)참기름 보다 비중, 굴절률, 옥소가, 비검화물, 불용성잡물의 함량이 더 컸었다. 3) 탈피(脫皮)참기름과 전(全)참기름의 지방상 조성은 서로 비슷하였으나 전자는 후자보다 불포화지방산의 함량이 다소 적었다. 4) 탈피(脫皮)참깨박(粕)은 전(全)참깨박(粕)보다 단백질 함량이 매우 높았다. 그리고 아미노산 조성은 서로 거의 비슷하였으며 이들의 박(粕)은 모두 methionine, Cystine, tryptophan 은 풍부하나 lysine 의 함량이 적었다. 5) 탈피(脫皮)참깨기름과 전(全)참깨기름중의 sesamol, sesamolin 및 sesamin 의 함량은 서로 차이점이 없었다. 6) 탈피(脫皮)참깨 및 그박(粕)은 전(全)참깨 및 그박(粕)보다 oxalate 및 calcium 의 함량이 적었다.

• 생약학회지
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• 제45권1호
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• pp.41-47
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• 2014

This study was conducted to investigate the content of foreign mineral materials and heavy metals (Pb, As, Cd, Hg) contained in commercial herbal medicines (1504 samples) classified by parts used, and the effect of removing heavy metals by washing treatment (take 50 g of the sample and put 1000 ml of distilled water, shake it gentle by hand for 1 min). The 5% trimmed means of acid-insoluble ash value (%) were as follows; above ground parts (0.76) and underground parts (0.52). Those of the total amount of individual heavy metals value (mg/kg) were as follows; caulis (1.33), flos (1.23), herba (0.91), cortex (0.76), rhizoma (0.73), radix (0.67), semen (0.44) and fructus (0.39). Acid-insoluble ash content was correlated with Pb in herbal medicines of underground parts (r=0.446) (p<0.01). After washing, the removal rate of heavy metals contained in 6 radix herbal medicines shows 33-13% respectively.

• Animal Bioscience
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• 제36권6호
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• pp.908-919
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• 2023

Objective: Information about the chemical composition of cassava-based feed ingredients is needed to accurately formulate animal diets. A study was conducted to determine the chemical composition of cassava-based feed ingredients and to test the hypothesis that there is variation in chemical composition among cassava products originating from different South-East Asian countries. Methods: Sources of dried peeled and unpeeled cassava roots, cassava chips, cassava meal, high-ash cassava meal, and cassava residue were used. All samples were analyzed for dry matter, gross energy, nitrogen, amino acids (AA), acid-hydrolyzed ether extract (AEE), ash, minerals, total starch, insoluble dietary fiber, and soluble dietary fiber. Samples of peeled and unpeeled cassava roots, cassava chips, and cassava meal were also analyzed for sugars. Results: High-ash cassava meal had greater (p<0.05) dry matter and ash, but lower (p<0.05) total starch and gross energy than all other cassava products. Peeled cassava roots, unpeeled cassava roots, and cassava chips had greater (p<0.05) total starch than the other cassava-based ingredients. Cassava residue had greater (p<0.05) concentrations of lysine, insoluble dietary fiber, and soluble dietary fiber compared with the other cassava products, but tryptophan and glutamic acid were greater (p<0.05) in peeled cassava roots, cassava chips, and cassava meal samples compared with the other ingredients. Concentration of most minerals was greater (p<0.05) in high-ash cassava meal than in the other cassava products. Conclusion: Cassava-based ingredients sold as peeled roots, unpeeled roots, chips, or meal have chemical compositions that are not different from each other, and peeling has little impact on chemical composition. High-ash cassava meal has lower nutritional quality compared with other cassava products due to low starch and gross energy. The high fiber content in cassava residue makes this ingredient more suitable for ruminants and sows than for younger pigs or poultry.

• Asian-Australasian Journal of Animal Sciences
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• 제15권11호
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• pp.1634-1638
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• 2002

Quantification of endogenous amino acid loss at the terminal ileum is an essential means for calculation of the true amino acid digestibility of a feedstuff. Since nitrogen appeared in the determined diet or not could shift the results very much, also, none of digestibility markers could be recovered with 100% rate at the terminal ileum, the objectives of the present study were: (1) to determine endogenous amino acid losses when fed either a casein diet or a protein-free diet and (2) to examine the reliability of chromic oxide or acid insoluble ash in the protein-free diet. Six ileal-cannulated pigs ($65{\pm}1.85 kg$ BW) with a simple T-cannula in the terminal ileum were used in a replicated $3{\times}3$ Latin square designed trial, after allowed a 14 d recuperation period. Each test period ran for 12 days comprised of a 10 d adjustment period and a 2 d collection period. The endogenous AA losses of His, Ile, Lys, Cys, Thr, Val, Trp, Asp, Glu, and Ser from pigs fed the casein diet were significantly higher than those of the protein-free diet (p<0.05). No significant difference was found in the amount of endogenous amino acid loss when determined with the different markers in the protein-free diet (p>0.05). These data suggest that endogenous amino acid loss could be underestimated when a protein-free diet is used. A direct effect of dietary peptides on the endogenous amino acid loss was found when the casein diet was fed. Our results also indicate that acid insoluble ash can be used as an inert marker as an alternative to chromic oxide when measuring endogenous amino acid loss.

• 대한본초학회지
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• 제31권3호
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• pp.71-75
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• 2016

Objectives : Mori Ramulus is a young branch of Morus alba Linne, which has been used as traditional medicines for antidiarrhea, antibacteria, and antihypertension in Korea. With the basis on these medicinal activities, it is registered at the Korean Herbal Pharmacopoeia. The standard for quality control in use, however, is not yet validated.Methods : We experiment on heavy metals test, TLC, loss on drying, ash, acid-insoluble ash, contents of ethanolsoluble extracts and contents of oxyresveratrol by using the 15 samples of Mori Ramulus which are collected domestically. We tested items according to the General Test, processes and apparatus, Crude Drugs Test of KP(2011).Results : Purity test(Heavy metals) showed contents for Pb, As, Hg, and Cd range of 0.1~1.1 ppm, 0.0~0.2 ppm, 0.00~0.01 ppm, and 0.00~0.02 ppm. Identification test(Thin layer chromatography) was on comparing with morucine standard solution in R_f value, all samples showed morucine spot (dark blue, R_f : 0.3) as same as R_f value of morucine-standard solution. Loss on drying was ranged from 5.1 to 8.9 %, ash and acid-insoluble ash were between the range 3.0~6.3% and 0.3~0.8%. Contents of ethanol-soluble extracts was ranged from 6.2 to 12.0%. Content of oxyresveratrol was ranged from 0.01 to 0.16 % based on the oxyresveratrol standard curve.Conclusions : We sincerely hope that this study will be contributed to the standardization and quality control of Korean herbal medicines.