• Title/Summary/Keyword: Accumulation chamber

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Effect of Occlusion on the Activities of Dermal Xanthine Oxidase in Rats (흰쥐에 있어서 피부노출 차단이 피부조직의 Xanthine Oxidase 활성에 미치는 영향)

  • 한선일;전태원;윤종국
    • Biomedical Science Letters
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    • v.6 no.1
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    • pp.37-43
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    • 2000
  • To investigate an impact of skin occlusion on the dermal xanthine oxidase (XO) activity, the dorsal part in rats was covered with closed petri dish-shaped chamber, 46 mm in diameter and 10 mm in height, which was made of glass. The crack between top of chamber and skin was sealed by an adhesive agent. After 5 days, the quantity of sweat accumulation was about 400 mg, whereas after 10 days that was decreased about to 21 mg. The 5 days skin occlusion showed the more increased activity of dermal XO compared with the control, and the increased ratio of enzyme activity to the control was higher than that of 10 days skin occlusion, with the increase being associated with sweat accumulation in chamber. Furthermore, the V$_{max}$ of dermal XO in 5 days skin occlusion was higher than that in the control. In conclusion, it may be hypothesized that the XO system may play an role for defence mechanism in dermal tissue.

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Compatibility Analysis Through the System of Chief, Deputy, Assistant, and Envoy for Socheongnyong-tang (소청룡탕(小靑龍湯)의 군신좌사(君臣佐使) 배오(配伍) 분석)

  • Kim, Do Hoy;Yoon, Michung;Shin, Soon Shik
    • Herbal Formula Science
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    • v.26 no.4
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    • pp.363-380
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    • 2018
  • Objectives : We analyzed the principle of compatibility of socheongnyong-tang and expanded the range of application in clinical practice. Methods : Socheongnyong-tang was analyzed by the compatibility principle through the system of chief, deputy, assistant, and envoy, but the basic formulas of "Discussion of Cold Damage" and "Synopsis of the Golden Chamber" was used. Results : Socheongnyong-tang treats exterior wind-cold and interior water accumulation. Exterior wind-cold is treated mainly by exterior-releasing herbs constituting mahwang-tang and gyeji-tang in "Discussion of Cold Damage", and interior water accumulation is treated mainly by retained fluid-resolving herbs constituting yeonggamomigangsinha-tang, yeonggamomigagangsinbanhahaengin-tang and yeonggamomigagangsinbanhaengdaehwang-tang in "Synopsis of the Golden Chamber". Depending on the weight of exterior wind-cold and interior water accumulation, the disease condition is classified as a case where exterior wind-cold is heavier than interior water accumulation, a case where exterior wind-cold is lighter than interior water accumulation, and a case where it is equivalent. When exterior wind-cold is heavier than interior water accumulation, chief herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series and deputy herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is equal to the disease condition of interior water accumulation, chief herbs are Ephedrae Herba of exterior-releasing herbs series and Zingiberis Rhizoma of retained fluid-resolving herbs series, and deputy herbs are Cinnamomi Ramulus of the exterior-releasing herbs series and Asari Radix et Rhizoma of retained fluid-resolving herbs series. When exterior wind-cold is lighter than interior water accumulation, chief herbs are Zingiberis Rhizoma and Asari Radix et Rhizoma of retained fluid-resolving herbs series and deputy herbs are Ephedrae Herba and Cinnamomi Ramulus of exterior-releasing herbs series. In any case, assistant herbs are Pinelliae Rhizoma, Paeoniae Radix alba, and Schisandrae Fructus, and envoy herb is Glycyrrhizae Radix preparata. Conclusions : In conclusion, socheongnyong-tang must differently formulate the system of chief, deputy, assistant, and envoy according to the grade of exterior wind-cold and interior water accumulation. These results suggest that socheongnyong-tang can be applied flexibly when applied in clinical practice to enhance the therapeutic effect.

Intraocular Foreign Body Entering the Anterior Chamber Through the Mouth: A Case Report

  • Kim, Joon-Young;Kim, Kyung-Hee;Jeong, Soon-Wuk
    • Journal of Veterinary Clinics
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    • v.34 no.1
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    • pp.58-60
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    • 2017
  • An 11-year-old, castrated Maltese dog presented with a 3-week history of periocular swelling, epiphora, and intermittent strabismus. On examination, a foreign body was observed in the anterior chamber, along with orbital cellulitis. Severe gingivitis and plaque accumulation were also diagnosed. The foreign body was surgically removed, and dental prophylaxis and dental extraction were performed. The foreign body entrance could not be found intraoperatively, and the foreign body, later identified as a feather, was removed through a clear corneal incision. The right maxillary molar, which had periodontal inflammation, was also extracted. One day postoperatively, severe hypopyon developed, although the periocular swelling was reduced. These signs persisted despite topical and systemic antibiotic and anti-inflammatory therapy; therefore, the right eye was enucleated 1 week later. Intraoperatively, a fistula was found connecting the orbital medial wall, right maxillary molar root, and sclera. The fistula entered the dorsomedial sclera approximately 7 mm behind the limbus. Enterobacteria were cultured from the area. Foreign bodies can enter the anterior chamber not only through the cornea, but also through the mouth. Therefore, when the entry point cannot be found in the cornea, a careful dental examination is required, and the foreign body must be removed through the sclera rather than the cornea.

The Effects of Operational and Mechanical Factors on the Performance of Rice-Husk Furnace (왕겨연소기(燃燒機)의 성능(性能)에 영향(影響)을 마치는 설계(設計) 및 작동인자(作動因子)에 관(關)한 연구(硏究))

  • Park, Seung Je;Noh, Sang Ha
    • Journal of Biosystems Engineering
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    • v.8 no.2
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    • pp.39-48
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    • 1983
  • This study was performed to obtain the basic data which could be used for the modification of the manual center-burner-type rice-husk furnace into a small scale automatic type for the multi-purpose use in the farm. For this purpose, first, the utilization feasibility of the rice-husk furnace in the farm was analyzed briefly in aspects of available amount of rice-husk for the fuel, annual operation time and replaceble amount of residential heating energy with rice-husk in the farm. For the experiment a prototype furnace geared with an automatic feeding device was fabricated, and feed rate, mold size and chimney height were changed to investigate the combustion efficiency of rice-husk and thermal efficiency of the furnace. Also, optimum and limiting operational factors were observed in each treatments. The results obtained are summarized as follows. 1. If the rice-husk is intensively used for residential heating in the farm for winter season, on an average 51 percent of the total heating energy can be replaced with the rice-husk. Therefore, development of a small scale automatic rice-husk furnace was recognized to be feasible. 2. The operational condition depending on husk-feed rates was very important factor for successive steady burning operation of the given furnace. When the feed-rate was 1.5 kg/hr, the top of the burning zone should be kept at the position about 55 cm from the bottom of the combustion chamber with the periodic removal of ash (termed as steady state position), which was 18 cm above the mold waist. When the feed rates were 2.4 kg/hr and 3.0 kg/hr, the steady state position was at about 4 cm above the mold waist. 3. The mold size affected inflow rate of air into the furnace and consequently CO content in the exhaust gas. The relatively bigger mold gave positive effect on the air-inflow rate. 4. When the husk-feed rates were 1.5 kg/hr, 2.4 kg/hr, 3.0 kg/hr, the combustion efficiencies of the rice-husk were 98.5%, 97.4% and 95.0%, the thermal efficiencies of the furnace were 93.4%, 93.2% and 87.6%, and CO content in the exhaust gas were 1.21%, 1.03%, and 2.43%, respectively. The air-inflow rates were decreased with the increase of feed rates. When the amount of excess air was 30-40%, the CO content in the exhaust gas was at the minimum level. 5. When the chimney height was lowered from 260 cm to 96 cm, the air-inflow rate was slightly decreased, but the average temperature in the combustion chamber, CO content in the exhaust gas and combustion and thermal efficiencies were not changed significantly. 6. The incidental problems associated with the protytype furnace were accumulation of the ash inside the mold, accumulation of the cinder between the outer-drum of the furnace and the combustion chamber wall, and accumulation of the cinder in the chimney.

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Characteristics of Formation and Growth of Aerosol Particles in an Indoor Smog Chamber (스모그 챔버 실험에 의한 에어로졸의 생성과 성장 현상의 관찰)

  • 김민철;배귀남;이승복;진현철;문길주;박주연;김용표
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2003.05b
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    • pp.43-44
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    • 2003
  • 스모그 챔버는 대기화학 반응을 물리적 변수를 제어할 수 있는 공간 내에서 재현하여 스모그 현상을 체계적으로 규명하기 위해 가장 많이 사용되는 방법이다(Dodge, 2000). 대기화학 반응을 통해 생성된 입자상 물질(secondary particles) 또는 초미세 입자(ultrafine particle, 〈0.1 $\mu\textrm{m}$)는 연속된 물리화학 반응을 통해 accumulation mode(0.1~l.0 $\mu\textrm{m}$) 입자로 성장한다. 특히, 대도시의 시정(visibility)은 accumulation mode 입자의 산란(scattering)과 흡수(adsorption)가 주요한 원인이기 때문에 이러한 물질의 생성에 영향을 주는 가스상 물질의 전화(gas-to-particle conversion) 반응과 초미세 입자의 성장 현상을 규명하는 것은 매우 중요하다. (중략)

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A Study on Mechanism about Contaminant Accumulation of Insulator Surface (애자표면의 오손물 누적에 관한 메커니즘 연구)

  • Park, Jae-Jun
    • The Journal of Information Technology
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    • v.8 no.2
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    • pp.85-91
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    • 2005
  • We studied a pollution mechanism for simulation of contamination environment in industrial concentrated area of around a metropolitan that made to circulated flow in the chamber. In case of the virgin both side of EPDM or Silicon insulator, we confirmed that the pollution to much more than service insulator in the field. Also contamination of initial state of the virgin didn't falling in spite of physical outside factor easily. This study confirmed to that the silicon was too much accumulated pollution contrast to EPDM insulator from scatter(spray) point to regular interval position use the Kaolin contaminant in the chamber. There are effected to the hydrophobicity of polymer insulator due to the pollution. In ceramic insulator, we get to know that pollution is much more at the Post insulator with vertical than with horizontal setup insulator.

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Measurement of the radon and thoron exhalation rates from the water surface of Yixin lake

  • Jiulin Wu;Shuaibin Liu;Tao Hu;Fen Lin;Ruomei Xie;Shuai Yuan;Haibo Yi;Yixiang Mo;Jiale Sun;Linquan Cheng;Huiying Li;Zhipeng Liu;Zhongkai Fan;Yanliang Tan
    • Nuclear Engineering and Technology
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    • v.56 no.4
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    • pp.1538-1543
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    • 2024
  • The importance of determining the radon exhalation rate from water surface is emphasized by the increased use of radon and its daughter products as tracers in large-scale circulation studies of the atmosphere. There were many methods to measure radon exhalation from water surface. With the development of radon exhalation rate measurement methods and instruments on the surface of the soil, the rock and building materials, so the radon exhalation rate from water surface can be more accurately measured by applying these improved methods and instruments. In this paper, a cuboid accumulation chamber surrounded by foam boards and a RAD7 were used to measure the radon exhalation rate on the water surface at three different positions by Yixin lake. Each measurement was performed 2 h. The radon exhalation rate from the water surface was about 6 × 10-3 Bq m-2s-1. The thoron exhalation rate from the water surface also can be estimated, it is about 0.16 Bq m-2s-1. These results hint that the radon transmission from the lake bottom soil to water and then into the atmosphere.

EFFECTS OF GINSENG SAPONIN ON ENDOTHELIUM - DEPENDENT VASCULAR RELAXATION IN RAT AORTA AND HYPERCHOLESTEROLEMIC RABBIT AORTA

  • Kim N.D.;Kang S.Y.
    • Proceedings of the Ginseng society Conference
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    • 1993.09a
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    • pp.40-48
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    • 1993
  • Intravenous administration of saponin extracted from the root of Panax ginseng lowered the blood pressure dose-dependently (10-200 mg/kg, B.W) in anesthetized rats. Therefore, experiments were designed to study the hypothesis that the lowering of blood pressure is associated with the release of endothelium-derived relaxing factor and the accumulation of guanosine 3, 5-cyclic monophosphate (cGMP). Rings of thoracic aorta with and without endothelium were suspended for the measurement of isometric tension in organ chamber and the tissue content of cGMP was measured by radioimmunoassay. All experiments were performed in the presence of $indomethacin(10^{-5}M).$ Ginseng saponin $(10^{-5}-3{\times}10^{-6}g/ml)$ relaxed contractions induced by phenylephrine $10^{-6}M)$ in the aorta with endothelium but not in that without endothelium. Treatment of aortic rings with $N^G$ monomethyl-L-arginine (L-NMMA, $10^{-4}M$ for 30 min), a competitive inhibitor of nitric oxide synthase, and methylene blue $(MB,\;3{\times}10^{-7}M$ for 30 min). an inhibitor of soluble guanylate cyclase, diminished the relaxation induced by Ginseng saponin. Ginseng saponin $10^{-4}g/ml$ for 2 min) increased the accumulation of cGMP in rings with endothelium. L-NMMA and MB inhibited the accumulation of cGMP induced by Ginseng saponin. These data suggest that vascular relaxations induced by Ginseng saponin are mediated by release of endothelium-derived relaxing factor and the accumulation of cGMP. The effect of Ginseng saponin on endothelial function in hypercholesterolemic rabbits was examined. In hypercholesterolemic rabbits fed with $2\%$ cholesterol for 8 weeks, relaxation of aortic rings to acetylcholine was impaired. The impaired relaxations of aortic rings in hypercholesterolemic rabbits were improved by dietary supplementation of Ginseng saponin, probably because of an improved release of endothelium - derived relaxing factor.

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A CFD Study on the Hydrogen Leakage for Residential Fuel cell System (가정용 연료전지 시스템 내부의 수소 누출에 관한 전산해석)

  • Ahn, Jae-Uk;Chung, Tae-Yong;Shin, Dong-Hoon;Nam, Jin-Hyun;Kim, Young-Gyu;Park, Ju-Won
    • Proceedings of the KSME Conference
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    • 2007.05b
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    • pp.2026-2031
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    • 2007
  • Hydrogen is receiving much research attention as an alternative substitute for hydrocarbon fuels these days due to its cleanliness and renewability. However, hydrogen should be used with caution because of its high propensity for leak and wide flammable range. This study deals with a situation that hydrogen leaks and then forms a flammable mixture inside 1kW class residential fuel cell. The residential fuel cell was modeled as a box-shaped chamber with vent openings at the top and bottom, filled with various components such as reformer, desulfurizer, fuel cell stack and humidifier. Computational fluid dynamics (CFD) was used to simulate the diffusion, buoyant flow and accumulation of leaked hydrogen in the modeled chamber. From the simulation, the risk region vulnerable to flame was identified and the methods to minimize such hazardous region was discussed. When the vent openings are 1% of the total surface, as the quantity of hydrogen leakage increases the risk regions increases accordingly. As the vent openings of the total surface increased from 1% to 2.3%, averaged hydrogen mole fraction is under 1% in the system.

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THE NUMERICAL SIMULATION OF HYDROGEN JET DIFFUSION FOR HYDROGEN LEAKAGE IN THE ENCLOSED GEOMETRY (밀폐공간에서 수소 누설로 인한 수소 제트 확산에 대한 수치해석)

  • Ahn, Hyuk-Jin;Lee, Sang-Hyuk;Hur, Nahm-Keon;Lee, Moon-Kyu;Yong, Gee-Joong
    • 한국전산유체공학회:학술대회논문집
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    • 2009.04a
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    • pp.176-182
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    • 2009
  • In the present study, a numerical simulation for the diffusion of hydrogen jet in a enclosure was performed to aid the leakage test of the hydrogen for the safety of the hydrogen vehicle. The temporal and spatial distributions of the hydrogen concentration in the test chamber are predicted from the present numerical analyses. Flammable region of 4-74% and explosive region of 18-59% hydrogen by volume was identified from the present results. Factors influencing the diffusion of the hydrogen jet were examined to evaluate the effectiveness of forced ventilation for relieving the accumulation of the leaked hydrogen gas in the chamber, which include location of open windows, size of leakage nozzle, and leakage rate among others. The distribution of the concentration of the leaked hydrogen for various cases can be used as a database in various applications for the hydrogen safety.

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