• Environmental Analysis Health and Toxicology
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• v.15 no.3
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• pp.99-106
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• 2000

Ethylenediaminetetraacetic acid (EDTA) and nitrilotriacetic acid (NTA) are various applied as chelating agents for metal ions, then they are widely used in many industrial processes and domestic products. A method is described for the determination of EDTA and NTA in water samples by GC/MS . The reaction temperature, reaction time and pH for esterification of EDTA and NTA were investigated using 10% sulfuric acid-methanol, ethanol and propanol. Optimum conditions were obtained by the esterification in 80$\^{C}$ for 1hr with ethanol. Method detection limits of ethylated EDTA and NTA in the 200 ml of water samples were 0.05 ng/ml, respectively, EDTA and NTA could be determined in the range of 0.05∼23.6 and 0.05∼7.0 ng/ml in treated water, and in the range of 0.06∼25.0 and 0.05∼6.40 ng/ml in raw water respectively. Risk assessments with EDTA and NTA exposure by drinking water ingestion were carried out. Based on the results of analysis, chronic daily intakes of EDTA and NTA would be less than the value of acceptable daily intake or tolerable daily intake.

• Structural Engineering and Mechanics
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• v.66 no.4
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• pp.423-438
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• 2018

This pioneer study focuses on finite element modeling and numerical modeling of three types of Reinforced Concrete Haunched Beams (RCHBs). Firstly, twenty RCHBs, consisting of three types, and four prismatic beams which had been tested experimentally were modeled via a nonlinear finite element method (NFEM) based software named as, ATENA. The modeling results were compared with experimental results including load capacity, deflection, crack pattern and mode of failure. The comparison showed a good agreement between the results and thus the model used can be effectively used for further studies of RCHB with high accuracy. Afterwards, new mechanism modes and design code equations were proposed to improve the shear design equation of ACI-318 and to predict the critical effective depth. These equations are the first comprehensive formulas in the literature involving all types of RCHBs. The statistical analysis showed the superiority of the proposed equation to their predecessors where the correlation coefficient, $R^2$ was found to be 0.89 for the proposed equation. Moreover, the new equation was validated using parametric and reliability analyses. The parametric analysis of both experimental and predicted results shows that the inclination angle and the compressive strength were the most influential parameters on the shear strength. The reliability analysis indicates that the accuracy of the new formulation is significantly higher as compared to available design equations and its reliability index is within acceptable limits.

• Journal of Korean Society on Water Environment
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• v.25 no.1
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• pp.84-89
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• 2009

Our nation's water resources remain susceptible to contamination by phenolic agrichemicals. These compounds can be toxic to a variety of organisms including humans. Their disposal is restricted in many countries with strict limits for acceptable concentrations in drinking water. Enzyme-mediated in situ stabilization has been advocated as an approach for the treatment of phenolic compounds in soils and groundwater. This study reports the development of a new approach to quantify the activity of the HRP enzyme in aqueous systems. The method is based on the coupled processes of energy transfer and enhanced chemiluminescence using a luminol-$H_2O_2$-HRP system. In this study, the effects of solution pH, ionic strength and aqueous concentrations of HRP, $H_2O_2$ and enhancer were evaluated on the p-iodophenol-enhanced, HRP-catalyzed chemiluminescence reaction intensity in Tris-HCl buffer. All assay components were found to affect the maximum chemiluminescene intensity. The calibration curve for HRP showed the linear relationship with maximum light intensity.

• Proceeding of KASS Symposium
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• 2008.05a
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• pp.61-65
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• 2008

A 4-story reinforced concrete structure built above an underground parking garage shows some slab deflections, and the deflections of the concrete floor slabs are proposed to be alleviated by the application of light-weight topping material in conjunction with localized strengthening of the slabs. The application of light-weight concrete topping on the existing slab has been simulated and its performance to anticipated loads has been analyzed. The application of light-weight topping material imposes additional weight on the exiting floor slabs. This added weight on the existing slabs causes over-stressing of the slabs. This over-stressing can be alleviated by enhancing the load carrying capacity of the existing slabs. Additional load carrying capacity in the existing slabs can be developed by localized strengthening of the slabs utilizing techniques such as the application of fiber-reinforced composites on the bottom surface of the slabs, and application of fiber-reinforced composites adequately complements the capacity of the existing slabs to bear the additional load imposed by light-weight leveling material. Additional moments in the beam and columns induced by the application of the light-weight topping material were tabulated and compared with capacity. The moment D/C ratios of the beam and columns are well the range of acceptable limits, and the beam and columns are not overstressed by the application of the surcharge.

• Archives of Reconstructive Microsurgery
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• v.9 no.1
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• pp.80-87
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• 2000

Acute high speed accidents that results in full thickness skin defect and exposure of tendon, nerve, vessel and periosteum over denuded bone demands soft tissue coverage. Exposed bone often ensues chronic infection and requires free flap transplantation which surely covers defects in one stage operation and enhances transport of oxygen-rich blood and converts a non-osteogenic or partially osteogenic site into a highly osteogenic site, but exposed bone which had performed free flap transplantation sometimes necroses and needs secondary bone procedure. Scar contracture limits joint motion should be excised and covered with normal soft tissue to restore normal range of motion. Authors have performed the large latissimus dorsi myocutaneous free flap in 8 cases of extensive soft tissue defect and exposed bone lesion in the leg and 1 case of the flap was failed. The secondary ilizarov bone procedure was performed in 3 of 8 cases. 2 cases of large burn scar contracture and 1 case of posttraumatic scar contracture in lower extremity were restored with the large latissimus dorsi myocutaneous free flap. Authors concluded that large latissimus dorsi myocutaneous free flap is the most acceptable microvascular procedure in large soft tissue defect combined with exposed periosteum and bone requiring secondary bone procedure and in large burn scar contracture limiting knee joint motion.

• Journal of the Korean Society of Safety
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• v.15 no.4
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• pp.139-149
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• 2000

This study aims to review and assess the existing postural classification schemes used for evaluating postural loads in industry. The schemes can be classified into three categories: self-report, observational and instrument-based techniques depending upon how to record working postures. Of the three techniques, this study was mainly focused on the observational methods. The observational technique is most widely used in the industrial sites because it does not interfere with work, and is easy and simple to use and cost-effective without requiring the use of expensive equipment for estimating the angular deviation of a body segment from the neutral position. In spite of the usefulness and applicability, the techniques have some problems: 1) The existing observational techniques lack the consistency in the class limits of the motion categories in each body segment; 2) Most of them do not provide the post-analysis criteria needed to judge whether or not any posture is acceptable in view point of the postural load; and 3) They can not precisely evaluate the postural load for a given posture because the external loads and dynamic factors including acceleration, moment and force were not taken into consideration.

• Membrane and Water Treatment
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• v.4 no.4
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• pp.265-275
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• 2013

China is one of the countries with the highest reserves of coal bed methane (CBM) in the world. Likewise, the CBM industry is significantly growing in China. However, activities related to CBM development have led to more environmental problems, which include serious environmental damage and pollution caused by CBM-produced water. In this paper, the detailed characteristics of CBM-produced water in the southern Qinshui Basin were investigated and analyzed and compared with local surface water and coal mine drainage. Most of CBM-produced water samples are contaminated by higher concentration of total dissolved solids (TDS), K (Potassium), Na (Sodium) and $NH_4$. The alkalinity of the water from coalmines and CBM production was higher than that of the local surface water. The concentrations of some trace elements such as P (Phosphorus), Ti (Titanium), V (Vanadium), Cr (Chromium), Ni (Nickel), Zn (Zinc), Ge (Germanium), As (Arsenic), Rb (Rubidium), and Pd (Palladium) in water from the coalmines and CBM production are higher than the acceptable standard limits. The ${\delta}D$ and ${\delta}^{18}O$ values of the CBM-produced water are lower than those of the surface water. Similarly, the ${\delta}D$ values of the CBM-produced water decreased with increasing drainage time.

• Clinical and Experimental Pediatrics
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• v.55 no.7
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• pp.219-223
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• 2012

Since the first umbilical cord blood transplantation (CBT) in 1998, cord blood (CB) has now become one of the most commonly used sources of hematopoietic stem cells for transplantation. CBT has advantages of easy procurement, no risk to donor, low risk of transmitting infections, immediate availability and immune tolerance allowing successful transplantation despite human leukocyte antigen disparity. Several studies have shown that the number of cells transplanted is the most important factor for engraftment in CBT, and it limits the wide use of CB in adult patients. New strategies for facilitating engraftment and reducing transplantation-related mortality are ongoing in the field of CBT and include the use of a reduced-intensity conditioning regimen, double-unit CBT, ex vivo expansion of CB, and co-transplantation of CB and mesenchymal stem cells. Recently, the results of two international studies with large sample sizes showed that CB is an acceptable alternative source of hematopoietic stem cells for adult recipients who lack human leukocyte antigen-matched adult donors. Along with the intensive researches, development in banking process of CB will amplify the use of CB and offer the chance for cure in more patients.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2011.10a
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• pp.550-555
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• 2011

The road traffic noise has emerged major noise as the overcrowding of the urban population and the explosion of car storage capacity. There are limits for establishing the measures to meet noise standard because of the increase of high-rise building and insufficient distance between residential areas and road in urban center areas. Therefore, this study analyze the problem of the application of national road noise standard, and present the alternatives to achieve environmental standards in conjunction with the soundproofing measures. To reduce the population ratio exposed to road noise on seoul motorway, we suggest some action plane are as follows: i) Roadside noise standard of nighttime beside daytime is the first noise reduction goals ii) Noise standard of Noise and vibration control act is priority in case of existing area iii) Noise standard of basic environmental policy act is priority in case of new area.

• Biomolecules & Therapeutics
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• v.10 no.3
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• pp.180-185
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• 2002

The bioequivalence of two 4 mg triamcinolone tablets (Dong-Kwang Triamcinolone$\textregistered$ vs. Wyeth Korea Ledercoat$\textregistered$) was assessed in healthy male volunteers after oral administration of 16mg triamcinolone in a randomized crossover study. Blood samples were collected at specified time intervals, and plasma was analyzed for triamcinolone using a validated HPLC method. The pharmacokinetic parameters of $T_{max}$, $C_{max}$, $AUC_{0\longrightarrowlast}$, $AUC_{0\longrightarrowinf}$ and $T_{1/2, \beta} were determined from plasma concentration-time profile of two formulations. The pharmacokinetic parameters were statistically compared to evaluate bioequivalence between two formulations, according to Korea Food and Drug Administration Guideline. The analysis of variance did not show any significant difference between the two formulations and 90% confidence limits fell within the acceptable range (80-120%) for bioequivalence. Based on these data it was concluded that the two products showed comparable pharmacokinetic profiles and that the Dong-Kwang triamcinlone$\textregistered$ tablet is bioequivalent to the Wyeth Korea Ledercoat$\textregistered$ tablet.