• 제목/요약/키워드: Absorption model

검색결과 1,114건 처리시간 0.026초

2차 다항회귀 메타모델을 이용한 달착륙선 충격흡수 시스템의 순차적 근사 최적설계 (Sequential Approximate Optimization of Shock Absorption System for Lunar Lander by using Quadratic Polynomial Regression Meta-model)

  • 오민환;조영민;이희준;조진연;황도순
    • 한국항공우주학회지
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    • 제39권4호
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    • pp.314-320
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    • 2011
  • 본 연구에서는 2단으로 구성된 달착륙선 충격 흡수 장치에 대한 최적화를 수행하였다. 충격 흡수 장치의 복잡한 충격거동을 모사하기 위해 1차원 구성방정식 모델을 제안하였으며, 이와 함께 상용해석 소프트웨어인 ABAQUS를 활용하여 최적화를 위한 2차 다항회귀 메타모델을 구성하였다. 구성된 메타모델을 순차적 근사 최적설계 기법에 적용하여 2단 충격 흡수 장치의 최적화를 수행하였으며, 이를 통해 허니컴 구조를 이용한 충격 흡수장치의 셀크기와 포일 두께를 변화시킴에 따라 달착륙선의 월면 착륙 시 충격하중을 크게 저감시킬 수 있음을 확인하였다.

Gintonin absorption in intestinal model systems

  • Lee, Byung-Hwan;Choi, Sun-Hye;Kim, Hyeon-Joong;Park, Sang-Deuk;Rhim, Hyewhon;Kim, Hyoung-Chun;Hwang, Sung-Hee;Nah, Seung-Yeol
    • Journal of Ginseng Research
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    • 제42권1호
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    • pp.35-41
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    • 2018
  • Background: Recently, we identified a novel ginseng-derived lysophosphatidic acid receptor ligand, called gintonin. We showed that gintonin induces $[Ca^{2+}]i$ transient-mediated morphological changes, proliferation, and migration in cells expressing lysophosphatidic acid receptors and that oral administration of gintonin exhibits anti-Alzheimer disease effects in model mice. However, little is known about the intestinal absorption of gintonin. The aim of this study was to investigate gintonin absorption using two model systems. Methods: Gintonin membrane permeation was examined using a parallel artificial membrane permeation assay, and gintonin absorption was evaluated in a mouse everted intestinal sac model. Results: The parallel artificial membrane permeation assay showed that gintonin could permeate an artificial membrane in a dose-dependent manner. In the everted sac model, gintonin absorption increased with incubation time (from 0 min to 60 min), followed by a decrease in absorption. Gintonin absorption into everted sacs was also dose dependent, with a nonlinear correlation between gintonin absorption and concentration at 0.1-3 mg/mL and saturation at 3-5 mg/mL. Gintonin absorption was inhibited by the Rho kinase inhibitor Y-27632 and the sodiumeglucose transporter inhibitor phloridzin. Moreover, lipid extraction with methanol also attenuated gintonin absorption, suggesting the importance of the lipid portion of gintonin in absorption. This result shows that gintonin might be absorbed through passive diffusion, paracellular, and active transport pathways. Conclusion: The present study shows that gintonin could be absorbed in the intestine through transcellular and paracellular diffusion, and active transport. In addition, the lipid component of gintonin might play a key role in its intestinal absorption.

Numerical Study on Simultaneous Heat and Mass Transfer in a Falling Film of Water-Cooled Vertical Plate Absorber

  • Phan, Thanh-Tong;Song, Sung-Ho;Moon, Choon-Geun;Kim, Jae-Dol;Kim, Eun-Pil;Yoon, Jung-In
    • 한국마린엔지니어링학회:학술대회논문집
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    • 한국마린엔지니어링학회 2002년도 춘계학술대회논문집
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    • pp.41-47
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    • 2002
  • A model of simultaneous heat and mass transfer process in absorption of refrigerant vapor into a lithium bromide solution of water-cooled vertical plate absorber was developed. The model can predict temperature and concentration profiles as well as the absorption heat and mass fluxes, the total heat and mass transfer rates and the heat and mass transfer coefficients. Besides, the effect of operating condition on absorption mass flux has been investigated, with the result that the absorption mass flux is increased as the inlet cooling water temperature decreases, the system pressure increases and the inlet solution concentration increases. And among the effects of operating parameters on absorption mass flux, the effect of inlet solution concentration is dominant.

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적외선 흡수필름을 차광재로 사용한 모형 온실의 광환경 분석(농업시설) (Analysis of the Light Environment in Model Greenhouse using Infrared Absorption Film as Shading Screen)

  • 권혁진;김기성;김문기
    • 한국농공학회:학술대회논문집
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    • 한국농공학회 2000년도 학술발표회 발표논문집
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    • pp.340-345
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    • 2000
  • This study was carried out to analyze the light and thermal environment in model greenhouse using infrared absorption film as shading screen and to compare with the case of no shading and using general shading screen such as aluminum foil-backed film, black polyethylene film and thermal blanket. PPFD(photosynthetic photon flux density) of inside the model greenhouse under infrared absorption film was increased by 22% than under general shading screen on the average. And temperature of inside air under infrared absorption film was 2$^{\circ}C$ lower than under general shading screen on the average. So, it is expected that infrared absorption film is useful as shading screen.

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백색 발광다이오드에서의 혼합 형광체 모델링 (Modeling of Mixed Phosphors in White Light Emitting Diode)

  • 김도우;공다영;공명국
    • 한국전기전자재료학회논문지
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    • 제26권7호
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    • pp.567-574
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    • 2013
  • An optical model is proposed in the white LED using phosphor and LED chip. In this paper a new model that describes the absorption rate and quantum efficiency with increasing the mixing ratio of phosphor in silicone, and the allotment of the phosphor absorption optical power in the several phosphor mixing in the silicone. Single phosphor in silicone from the optical measurement data before and after molding, the solution to get the blue optical power and the phosphor emission optical power is proposed. By these solution the absorption rate and the quantum efficiency was obtained. The model with single phosphor mixing in the silicone the validity was confirmed.

수분 흡수가 단열재의 열전도계수에 미치는 영향에 관한 연구 (A Study on the Effects of Water Absorption on the Thermal Conductivity of Insulation Materials)

  • 유성연;김태호
    • 설비공학논문집
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    • 제25권3호
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    • pp.119-125
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    • 2013
  • IInsulation material is generally used for preventing heat loss from heat transport fluids, and water absorption severely reduces the insulation property. The purpose of this study is to evaluate the amount of water absorption supplied by the pouring method and spraying method, to investigate the effects of water absorption on the thermal conductivity of an insulation material, and modeling the relation between water absorption and thermal conductivity. E-glass, a kind of glass fiber, and HYPERLITE, mainly composed of pearlite, are selected, to compare hygroscopic and insulation properties. E-glass is found to have much higher water absorptivity, compared to HYPERLITE. The thermal conductivity of the water-absorbed E-glass is increased by more than 150%, compared to that of no absorption, while variation of the thermal conductivity of HYPERLITE with water absorption is insignificant. A three-stage model of water absorption for thermal conductivity is developed, and the modeling results are found to be in good agreement with the experimental data.

Load transfer and energy absorption in transversely compressed multi-walled carbon nanotubes

  • Chen, Xiaoming;Ke, Changhong
    • Coupled systems mechanics
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    • 제6권3호
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    • pp.273-286
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    • 2017
  • We present a simple and easy-to-implement lumped stiffness model to elucidate the load transfer mechanism among all individual tube shells and intertube van der Waals (vdW) interactions in transversely compressed multi-walled carbon nanotubes (CNTs). Our model essentially enables theoretical predictions to be made of the relevant transverse mechanical behaviors of multi-walled tubes based on the transverse stiffness properties of single-walled tubes. We demonstrate the validity and accuracy of our model and theoretical predictions through a quantitative study of the transverse deformability of double- and triple-walled CNTs by utilizing our recently reported nanomechanical measurement data. Using the lumped stiffness model, we further evaluate the contribution of each individual tube shell and intertube vdW interaction to the strain energy absorption in the whole tube. Our results show that the innermost tube shell absorbs more strain energy than any other individual tube shells and intertube vdW interactions. Nanotubes of smaller number of walls and outer diameters are found to possess higher strain energy absorption capacities on both a per-volume and a per-weight basis. The proposed model and findings on the load transfer and the energy absorption in multi-walled CNTs directly contribute to a better understanding of their structural and mechanical properties and applications, and are also useful to study the transverse mechanical properties of other one-dimensional tubular nanostructures (e.g., boron nitride nanotubes).

관류 랫드 장관모델에서의 케토프로펜의 흡수기전 연구 (Mechanistic Studies of Ketoprofen Absorption in Perfused Rat Intestine Model)

  • 김미정
    • Journal of Pharmaceutical Investigation
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    • 제37권2호
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    • pp.73-78
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    • 2007
  • The aim of this study was to investigate the absorption properties of ketoprofen. The in-situ perfusion model has advantages over in vitro models as it provides intact lymphatic and blood flow circulation. The absorption properties of six different concentrations of ketoprofen have been studied in single pass in-situ rat intestine model. $^{14}C-PEG$ 4000 was used as a permeability marker and the possibility of an energy dependent contribution to ketoprofen absorption was also Investigated using the metabolic inhibitor sodium azide. Three different concentrations of sodium azide were studied to examine its effect on absorption of ketoprofen from the rat intestine. The findings of this study suggest that mono-carboxylic type drugs like ketoprofen cause permeability changes in the intestine. This is shown by the increase in absorption of $^{14}C-PEG$ 4000 as the concentration of ketoprofen is increased. However, the trend for ketoprofen permeability is to decrease over the concentration ranges. It was observed that the Papp values for ketoprofen with sodium azide shows a trend towards reduction in the amount of ketoprofen absorbed from the rat intestine which was significantly different (p<0.05) from that of ketoprofen with sodium azide 3.0mM. This indicates that sodium azide has an affect on the absorption of ketoprofen. The pH of all the perfusion solutions was altered to ${\sim}pH\;6.7$ by the buffering capacity of the small intestine secretions. The results suggest that mechanisms other than passive diffusion may be involved in ketoprofen absorption. This would be consistent with the involvement of active transport or saturatable processes in the absorption of drugs containing monocarboxylic acid group, as has been previously suggested from in vitro data.

Effect of radiation model on simulation of water vapor - hydrogen premixed flame using flamelet combustion model in OpenFOAM

  • Kim, Sangmin;Kim, Jongtae
    • Nuclear Engineering and Technology
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    • 제54권4호
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    • pp.1321-1335
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    • 2022
  • This study was conducted to investigate the effect of absorption coefficient models on the P1 radiation model for a premixed hydrogen flame containing the water vapor. A CFD combustion simulation analysis was performed using XiFoam, one of the open-source CFD solvers in OpenFOAM. The solver using the flamelet combustion model has been modified to implement radiative heat transfer. The absorption coefficient models used in this study the grey-mean model and constant model, and for comparison, case without radiation was added. This CFD simulation study consisted of benchmarking the THAI HD-15 and HD-22 experiments. The difference between the two tests is the inclusion of water vapor in the condition before ignition. In the case of the HD-22 experiment containing water vapor in the initial condition, the simulation results show that the grey-mean absorption coefficient model has a strong influence on the temperature decrease of the flame and on the change in pressure inside the vessel.

C2C 옥션 플랫폼 사용자의 충동적 입찰행동에 관한 연구 (Users' Impulsive Bidding Behavior in C2C Auction Platform)

  • 박상철;김종욱
    • 한국정보시스템학회지:정보시스템연구
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    • 제25권4호
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    • pp.63-85
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    • 2016
  • Purpose While the popularity of C2C auction platforms such as eBay is gradually decreased, this domain is still undermined to explain online bidding behaviors. Online bidders sometimes engage in impulsive bidding due to some of the online auction characteristics. Therefore, this study develops and tests a model of the impulsive bidding exhibited by online bidders in C2C auction platforms. Based on S-O-R framework, our model posits that both perceived time-pressure and competition intensity affect cognitive absorption which ultimately influences the impulsive bidding. Design/methodology/approach This study collected survey data from 214 C2C auction participants, who have prior experience on impulsive bidding and tested both measurement model and structural model by using CB-SEM (covariate-based structural equation modelling) technique. In this study, by using AMOS 20.0, we tested the measurement model for its overall fit, item reliability, and validity and further conducted the structural model to test our proposed hypotheses. Findings Based on our results, we found that perceived tim-pressure and competition intensity were positively related to cognitive absorption. We also found that the cognitive absorption was positively associated with impulsive bidding behavior. In this study, by developing our research model in S-O-R framework, we provide an alternative theoretical mechanism to describe online impulsive bidding behavior.