• Title/Summary/Keyword: Absorption Function

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Anti-aging effects of Korean Red Ginseng (KRG) in differentiated embryo chondrocyte (DEC) knockout mice

  • Nam, Youn Hee;Jeong, Seo Yule;Kim, Yun Hee;Rodriguez, Isabel;Nuankaew, Wanlapa;Bhawal, Ujjal K.;Hong, Bin Na;Kang, Tong Ho
    • Journal of Ginseng Research
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    • v.45 no.1
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    • pp.183-190
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    • 2021
  • Background: The circadian rhythm is the internal clock that controls sleep-wake cycles, metabolism, cognition, and several processes in the body, and its disruption has been associated with aging. The differentiated embryo chondrocyte (Dec) gene is related to circadian rhythm. To our knowledge, there are no reports of the relationship between dec gene expression and KRG effect. Therefore, we treated Dec gene knockout (KO) aging mice with KRG to study anti-aging related effects and possible mechanisms. Methods: We evaluated KRG and expression of Dec genes in an ototoxicity model. Dec genes expression in livers of aging mice was further analyzed. Then, we assessed the effects of DEC KO on hearing function in mice by ABR. Finally, we performed DNA microarray to identify KRG-related gene expression changes in mouse liver and assessed the results using KEGG analysis. Results: KRG decreased the expression of Dec genes in ototoxicity model, which may contribute to its anti-aging efficacy. Moreover, KRG suppressed Dec genes expression in liver of wild type indicating inhibition of senescence. ABR test indicated that KRG improved auditory function in aging mouse, demonstrating KRG efficacy on aging related diseases. Conclusion: Finally, in KEGG analysis of 238 genes that were activated and 158 that were inhibited by KRG in DEC KO mice, activated genes were involved in proliferation signaling, mineral absorption, and PPAR signaling whereas the inhibited genes were involved in arachidonic acid metabolism and peroxisomes. Our data indicate that inhibition of senescence-related Dec genes may explain the anti-aging efficacy of KRG.

Analysis on the Changes in Abandoned Paddy Wetlands as a Carbon Absorption Sources and Topographic Hydrological Environment (탄소흡수원으로서의 묵논습지 변화와 지형수문 환경 분석)

  • Miok, Park;Sungwon, Hong;Bonhak, Koo
    • Land and Housing Review
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    • v.14 no.1
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    • pp.83-97
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    • 2023
  • The study aims to provide an academic basis for the preservation and restoration of abandoned paddy wetland and the enhancement of its carbon accumulation function. First, the temporal change of the wetlands was analysed, and a typological classification system for wetlands was attempted with the goal of carbon reduction. The types of wetland were classified based on three variables: hydrological environment, vegetation, and carbon accumulation, with a special attention on the function of carbon accumulation. The types of abandoned paddy wetlands were classified into 12 categories based on hydrologic variables- either high or low levels of water inflow potential-, vegetation variables with either dominance of aquatic plants or terrestrial plants, and three carbon accumulation variables including organic matter production, soil organic carbon accumulation, and decomposition. It was found that the development period of abandoned paddy analyzed with aerial photographs provided by the National Geographic Information Institute happened between 2010 and 2015. In the case of the wetland in Daejeon 1 (DJMN01) farming stopped by 1990 and it appeared to be a similar structure to natural wetlands after 2010 . Over the past 40 years the abandoned paddy wetland changed to a high proportion of forests and agricultural lands. As time went by, such forests and agricultural lands tended to decrease rapidly and the lands were covered by artificial grass and other types of forests.

Hypersensitive Large Intestine Syndrome in Hyungsang Medicine (과민성대장증후군의 형상의학적 고찰 -동의보감(東醫寶鑑)을 중심으로-)

  • Choi Byung-Tae;Choi Yung-Hyun;Han Jin-Soo;Lee Yong-Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1129-1136
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    • 2005
  • The writer reports the conclusions gained from study about the cause of the hypersensitive large intestine syndrome with Dongeuibogam as the central figure through researching the disharmony among Body Essence, Vital Energy, Mentality, and Blood, mutual action of five viscera and six bowels, and external shapes. The hypersensitive large intestine syndrome is generally chronic and recurred in many cases, so it is more efficacious than symptomatic to treat according to find the contradictions of individual shapes. The shapes and cases suffering frequently the hypersensitive large intestine syndrome are Gi-kwa and Sin-kwa, having a long nose, having a bruised spot on Triple warmer, man with inclined mouth, Taeeum type, man with congested fluids, man with colic symptoms. The hypersensitive large intestine syndrome in Oriental medicine is recognized of diarrhea, constipation, abdominal pain, abdominal distention and fullness caused by seven emotions. In Dongeuibogam it can be found out the similarity in depressive symptoms due to disorder of Gi, stagnation of Gi, dysphasia due to disorder of Gi, diarrhea due to disorder of Gi, fullness of due to Gi, diarrhea due to phlegm-retention, retention of undigested food, immoderate drinking, hypo-function of the spleen, or deficiency, abdominal pain from colic symptom, and difficulty in defecation and urination, internal injury, diarrhea due to weakness and fatigue. If the Jung, Gi, Sin, and Hyul composed the human body is broken harmony, the function of large intestinal transmission would be fallen, so similar symptoms like the hypersensitive large intestine syndrome are gotten. Especially Gi-kwa suffers diarrhea, constipation abdominal pain, and abdominal distention and fullness due to depressive symptoms from disorder of Seven emotions or Seven Gi. And Sin-kwa suffers from the hypersensitive large intestine syndrome due to emotional restlessness having an influence on rhythmic movement of abdomen. Examining between five viscera and six bowels and the hypersensitive large intestine syndrome, Liver cannot disperse well having influence on mutual relation of Liver-Large intestine, Heart reduces the function of defecation and urination not to control the seven emotions, Lung having exterior and interior relation with intestine has an influence on primordial energy and let the main symptoms occur, Spleen circulating the body fluid let the main symptoms occur due to malfunction of circulation, Kidney locating in lower part of the body has deep connection with intestine, so let the disorder. Urinary bladder is connected with intestine in moisture metabolism, Stomach is connected in receive and transmission, Small intestine is connected in absorption and excretion, from small intestine pain disturbing the abdominal movement, Samcho managing the catharsis of lower heater if declined its function causes the hypersensitive large intestine syndrome. The colic symptoms of Front private parts which disorder in lower abdomen give rise to abdominal pains, difficulty in defecation and urination due to Cold are similar to the hypersensitive large intestine syndrome. The treatments of applying the shapes of colic syndrome advocated by Master Park can be efficacious cure in clinic. Researching after the clinical cases of Master Park advocating Hyungsang medicine, we came to know that plenty of prescriptions of internal injury are applied and take good effects.

Derivation of Green Infrastructure Planning Factors for Reducing Particulate Matter - Using Text Mining - (미세먼지 저감을 위한 그린인프라 계획요소 도출 - 텍스트 마이닝을 활용하여 -)

  • Seok, Youngsun;Song, Kihwan;Han, Hyojoo;Lee, Junga
    • Journal of the Korean Institute of Landscape Architecture
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    • v.49 no.5
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    • pp.79-96
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    • 2021
  • Green infrastructure planning represents landscape planning measures to reduce particulate matter. This study aimed to derive factors that may be used in planning green infrastructure for particulate matter reduction using text mining techniques. A range of analyses were carried out by focusing on keywords such as 'particulate matter reduction plan' and 'green infrastructure planning elements'. The analyses included Term Frequency-Inverse Document Frequency (TF-IDF) analysis, centrality analysis, related word analysis, and topic modeling analysis. These analyses were carried out via text mining by collecting information on previous related research, policy reports, and laws. Initially, TF-IDF analysis results were used to classify major keywords relating to particulate matter and green infrastructure into three groups: (1) environmental issues (e.g., particulate matter, environment, carbon, and atmosphere), target spaces (e.g., urban, park, and local green space), and application methods (e.g., analysis, planning, evaluation, development, ecological aspect, policy management, technology, and resilience). Second, the centrality analysis results were found to be similar to those of TF-IDF; it was confirmed that the central connectors to the major keywords were 'Green New Deal' and 'Vacant land'. The results from the analysis of related words verified that planning green infrastructure for particulate matter reduction required planning forests and ventilation corridors. Additionally, moisture must be considered for microclimate control. It was also confirmed that utilizing vacant space, establishing mixed forests, introducing particulate matter reduction technology, and understanding the system may be important for the effective planning of green infrastructure. Topic analysis was used to classify the planning elements of green infrastructure based on ecological, technological, and social functions. The planning elements of ecological function were classified into morphological (e.g., urban forest, green space, wall greening) and functional aspects (e.g., climate control, carbon storage and absorption, provision of habitats, and biodiversity for wildlife). The planning elements of technical function were classified into various themes, including the disaster prevention functions of green infrastructure, buffer effects, stormwater management, water purification, and energy reduction. The planning elements of the social function were classified into themes such as community function, improving the health of users, and scenery improvement. These results suggest that green infrastructure planning for particulate matter reduction requires approaches related to key concepts, such as resilience and sustainability. In particular, there is a need to apply green infrastructure planning elements in order to reduce exposure to particulate matter.

Prioritization of Species Selection Criteria for Urban Fine Dust Reduction Planting (도시 미세먼지 저감 식재를 위한 수종 선정 기준의 우선순위 도출)

  • Cho, Dong-Gil
    • Korean Journal of Environment and Ecology
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    • v.33 no.4
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    • pp.472-480
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    • 2019
  • Selection of the plant material for planting to reduce fine dust should comprehensively consider the visual characteristics, such as the shape and texture of the plant leaves and form of bark, which affect the adsorption function of the plant. However, previous studies on reduction of fine dust through plants have focused on the absorption function rather than the adsorption function of plants and on foliage plants, which are indoor plants, rather than the outdoor plants. In particular, the criterion for selection of fine dust reduction species is not specific, so research on the selection criteria for plant materials for fine dust reduction in urban areas is needed. The purpose of this study is to identify the priorities of eight indicators that affect the fine dust reduction by using the fuzzy multi-criteria decision-making model (MCDM) and establish the tree selection criteria for the urban planting to reduce fine dust. For the purpose, we conducted a questionnaire survey of those who majored in fine dust-related academic fields and those with experience of researching fine dust. A result of the survey showed that the area of leaf and the tree species received the highest score as the factors that affect the fine dust reduction. They were followed by the surface roughness of leaves, tree height, growth rate, complexity of leaves, edge shape of leaves, and bark feature in that order. When selecting the species that have leaves with the coarse surface, it is better to select the trees with wooly, glossy, and waxy layers on the leaves. When considering the shape of the leaves, it is better to select the two-type or three-type leaves and palm-shaped leaves than the single-type leaves and to select the serrated leaves than the smooth edged leaves to increase the surface area for adsorbing fine dust in the air on the surface of the leaves. When considering the characteristics of the bark, it is better to select trees that have cork layers or show or are likely to show the bark loosening or cracks than to select those with lenticel or patterned barks. This study is significant in that it presents the priorities of the selection criteria of plant material based on the visual characteristics that affect the adsorption of fine dust for the planning of planting to reduce fine dust in the urban area. The results of this study can be used as basic data for the selection of trees for plantation planning in the urban area.

An Experimental Study on Real Time CO Concentration Measurement of Combustion Gas in LPG/Air Flame Using TDLAS (TDLAS를 이용한 LPG/공기 화염 연소가스의 실시간 CO 농도 측정에 관한 연구)

  • So, Sunghyun;Park, Daegeun;Park, Jiyeon;Song, Aran;Jeong, Nakwon;Yoo, Miyeon;Hwang, Jungho;Lee, Changyeop
    • Clean Technology
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    • v.25 no.4
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    • pp.316-323
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    • 2019
  • In order to enhance combustion efficiency and reduce atmosphere pollutants, it is essential to measure carbon monoxide (CO) concentration precisely in combustion exhaust. CO is the important gas species regarding pollutant emission and incomplete combustion because it can trade off with NOx and increase rapidly when incomplete combustion occurs. In the case of a steel annealing system, CO is generated intentionally to maintain the deoxidation atmosphere. However, it is difficult to measure the CO concentration in a combustion environment in real-time, because of unsteady combustion reactions and harsh environment. Tunable Diode Laser Absorption Spectroscopy (TDLAS), which is an optical measurement method, is highly attractive for measuring the concentration of certain gas species, temperature, velocity, and pressure in a combustion environment. TDLAS has several advantages such as sensitive, non-invasive, and fast response, and in-situ measurement capability. In this study, a combustion system is designed to control the equivalence ratio. Also, the combustion exhaust gases are produced in a Liquefied Petroleum Gas (LPG)/air flame. Measurement of CO concentration according to the change of equivalence ratio is confirmed through TDLAS method and compared with the simulation based on Voigt function. In order to measure the CO concentration without interference from other combustion products, a near-infrared laser at 4300.6 cm-1 was selected.

Influence of water absorption on flexural strength and elastic modulus in several resinous teeth splinting materials (수분 흡수가 여러 레진계 치아고정 재료의 굴곡강도와 탄성계수에 미치는 영향)

  • Park, Bae-Young;Kim, Soo-Yeon;Kim, Jin-Woo;Park, Se-Hee;Cho, Kyung-Mo
    • Journal of Dental Rehabilitation and Applied Science
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    • v.34 no.2
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    • pp.72-79
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    • 2018
  • Purpose: The purpose of this study was to compare flexural strength and elastic modulus of several splinting materials dependent on water absorption. Materials and Methods: Three different materials; LightFix, G-FIX, G-aenial Universal Flo; were used in this study. Thirty rectangular bar specimens ($25{\times}2{\times}2mm$) of each materials were prepared. Fifteen specimens of each materials were stored in 100% relative humidity atmosphere, $37^{\circ}C$ for 24 hours. The other specimens were stored in distilled water, $37^{\circ}C$ for 30 days. Flexural strength and elastic modulus were calculated using Universal testing machine. One-way ANOVA and Scheffe's post hoc test at 95% level of significance were used on all test results. Results: In LightFix, flexural strength and elastic modulus were significantly decreased after aging. In G-FIX, there was no significant change in flexural strength and elastic modulus after aging. In G-aenial Universal Flo, flexural strength was significantly decreased, but elastic modulus did not change significantly. Statistical analysis reveals that flexural strength and elastic modulus increased in the order of LightFix, G-FIX, G-aenial Flo in both 24 hours and 30 days. Conclusion: It could be deduced from this study that flexural strength and elastic modulus of some resins could be changed when it aged in oral environment. Thus this should be considered when choosing a resin to perform a resin-bonded splint.

Soft X-ray Synchrotron-Radiation Spectroscopy Study of [Co/Pd] Multilayers as a Function of the Pd Sublayer Thickness (Pd층의 두께 변화에 따른 [Co/Pd] 다층박막의 연엑스선 방사광 분광 연구)

  • Kim, D.H.;Lee, Eunsook;Kim, Hyun Woo;Seong, Seungho;Kang, J.-S.;Yang, Seung-Mo;Park, Hae-Soo;Hong, JinPyo
    • Journal of the Korean Magnetics Society
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    • v.26 no.4
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    • pp.124-128
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    • 2016
  • We have investigated the electronic structures of intermetallic multilayer (ML) films of [$Co(2{\AA})/Pd(x{\AA})$] (x: the thickness of the Pd sublayer; x = $1{\AA}$, $3{\AA}$, $5{\AA}$, $7{\AA}$, $9{\AA}$) by employing soft X-ray absorption spectroscopy (XAS) and soft X-ray magnetic circular dichroism (XMCD). Both Co 2p XAS and XMCD spectra are found to be similar to one another, as well as to those of Co metal, providing evidence for the metallic bonding of Co ions in [Co/Pd] ML films. By analyzing the measured Co 2p XMCD spectra, we have determined the orbital magnetic moments and the spin magnetic moments of Co ions in [$Co(2{\AA})/Pd(x{\AA})$] ML films. Based on this analysis, we have found that the orbital magnetic moments are enhanced greatly when x increases from $1{\AA}$ to $3{\AA}$, and then do not change much for $x{\geq}3{\AA}$. This finding suggests that the interface spin-orbit coupling plays an important role in determining the perpendicular magnetic anisotropy in [Co/Pd] ML films.

A Study on the Bioavailability of Organic Ca in Growing Rats (성장기 흰쥐에서 유기태 칼슘의 체내 이용성 연구)

  • Park, Mi-Na;Cho, Su-Jung;Kim, Hee-Kyong;Kim, Jae-Hong;Kim, Min-Ho;Kim, Wan-Sik;Lee, Yeon-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.1
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    • pp.87-94
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    • 2012
  • We evaluated the bioavailability of a novel organic Ca supplement chelated with milk protein (CaMP) in growing rats and compared it with those of Ca carbonate and Ca citrate. Four-week-old male rats were divided into six groups (n=6/group) and fed AIN-93G-based experimental diets containing three Ca sources, Ca carbonate, Ca citrate, and CaMP at two levels, normal (0.5%, w/w) and high (1.5%, w/w), for 6 weeks. Growth, mineral contents of serum, Ca content and breaking force of femur, and Ca absorption were measured. There were no significant differences in weight gain or food intake, but food efficiency ratio (FER) of CaMP in the high Ca group was higher than those of other groups. Ca and P concentrations in serum were within normal range in all experimental rats. There was no difference in Ca content of the femur among all of the groups. Although there was no statistical significance in bone breaking force of the femur among the groups, the CaMP groups had a higher breaking force compared to other groups. Further, Ca absorption rate significantly increased in the CaMP groups (p<0.05). These results demonstrate that the CaMP supplement did not exhibit any negative effect on growth or Ca metabolism of the rats. Therefore, CaMP can be recommended as a good Ca supplement with regard to bone metabolism and Ca bioavailability.

Sensory and Physical Characteristics of Hwajeun Depended on the Various Levels of Oil Amounts and frying Time (기름의 양과 지지는 시간에 따른 화전의 관능적 및 물리적 특성)

  • 이승현;박정은;장명숙
    • Korean journal of food and cookery science
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    • v.19 no.6
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    • pp.765-771
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    • 2003
  • The aim of this study was to standardize the various methods and recipes of Hwajeun (glutinous rice pancake with flower) appeared in the literature. For this purpose, the effects on the sensory and rheological characteristics of Hwajeun in terms of the various levels of oil and frying times were investigated. This experiment consisted of a sensory evaluation in terms of the acceptance (color, flavor, oily feeling, softness, chewiness, adhesiveness, taste and overall preference) and objective evaluation performed by a texture analyzer, a color difference meter and measurements of the water content and oil absorption. The moisture content of the treatments as a function of the frying time, S7, showed a significantly(p<0.01) low value, and the oil absorption of the Hwajeun made with different frying times increased in proportion to the increment of the frying time(p<0.001). In terms of color, the b value of the Hwajeun made with 16g oil for frying showed a higher value than the others. In the two bite compression test, the hardness of the Hwajeun made with 4g oil for frying showed a significantly (p<0.001) high value among the S2 and S3 samples. As a result of the sensory evaluation for the Hwajeun made with various amounts of oil and frying times, the Hwajeun made with 16g oil for frying and a 2 min frying time for each side (S6) was the most preferred in terms of the softness, chewiness, taste and overall preference of the sensory evaluation