• Journal of Gastric Cancer
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• v.22 no.4
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• pp.339-347
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• 2022

Purpose: Lymphovascular invasion is a criterion for non-curative resection in patients who have undergone endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). We aimed to determine the rate of extragastric metastasis (EGM) and identify the predictors of EGM in patients with negative resection margins (R0 resection) and lymphovascular invasion in post-ESD pathology. Materials and Methods: A total of 2,983 patients underwent ESD for EGC. Among them, 110 had a pathology of R0 resection and positive lymphovascular invasion. Patients underwent additional gastrectomy (n=63) or further follow-up without gastrectomy (n=47). Results: The 110 patients were assigned to one of the 3 groups according to ESD indications based on post-ESD pathology. The first group satisfied the absolute indication for ESD (n=18), the second group satisfied the expanded indications for ESD (n=34), and the last group satisfied the beyond indication (n=58). The number of occurrences of EGM in each group was 1 (5.6%), 3 (8.8%), and 3 (5.2%), respectively. The logistic regression analysis adjusted for age, sex, tumor size, and indication for ESD, showed that larger tumor size was associated with EGM (odds ratio, 1.76; 95% confidence interval, 1.00-3.10; P=0.048). In contrast, ESD indication criteria did not affect EGM (P=0.349). Conclusions: Tumor size was the only predictive indicator for EGM in patients who underwent R0 resection and lymphovascular invasion on post-ESD pathology. Even patients with pathology corresponding to the absolute indication criteria of ESD had lymphovascular invasion, which means that they require additional gastrectomy due to the risk of EGM.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.3C
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• pp.209-214
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• 2003

Multi-mode coding method is a reliable DC-suppression method. There are two ways to improve the DC-suppression performance. One is improving scrambler's performance, and the other is improving selection criteria. The latter uses the MRDS(minimum running digital sum) criterion. It is easy to calculate, but its performance goes down when the length of codeword is getting longer. The MSW(mean squared weight) criterion that is known as the best so far regardless of the length of codeword has the high complexity. In this paper, we present the new selection criteria, MPRDS(minimum peak RDS) and A BSRDS(absolute RDS). Their performance are close to the MSW, implementation is simple. And also we present the SC(sign change) that has a subsidiary role with the original selection criteria and improve the capacity.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.11
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• pp.83-93
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• 2020

This empirical research aims to modeling and improving the forecasting accuracy of the volatility pattern by employing the Saudi Arabia stock market (Tadawul)by studying daily closed price index data from October 2011 to December 2019 with a number of observations being 2048. In order to achieve significant results, this study employs many mathematical functions which are non-linear spectral model Maximum overlapping Discrete Wavelet Transform (MODWT) based on the best localized function (Bl14), autoregressive integrated moving average (ARIMA) model and generalized autoregressive conditional heteroskedasticity (GARCH) models. Therefore, the major findings of this study show that all the previous events during the mentioned period of time will be explained and a new forecasting model will be suggested by combining the best MODWT function (Bl14 function) and the fitted GARCH model. Therefore, the results show that the ability of MODWT in decomposition the stock market data, highlighting the significant events which have the most highly volatile data and improving the forecasting accuracy will be showed based on some mathematical criteria such as Mean Absolute Percentage Error (MAPE), Mean Absolute Scaled Error (MASE), Root Means Squared Error (RMSE), Akaike information criterion. These results will be implemented using MATLAB software and R- software.

• Nuclear Engineering and Technology
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• v.50 no.6
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• pp.860-868
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• 2018

This article presents a new design of earthquake instrumentation that is suitable for quick decision-making after the seismic event at the nuclear power plant (NPP). The main objective of this work is to ensure more availability of the NPP by expediting walk-down period when the seismic wave is incident. In general, the decision-making to restart the NPP after the seismic event requires more than 1 month if an earthquake exceeds operating basis earthquake level. It affects to the plant availability significantly. Unnecessary shutdown can be skipped through quick assessments of operating basis earthquake, safe shutdown earthquake events, and damage status to structure, system, and components. Multidecision parameters such as cumulative absolute velocity, peak ground acceleration, Modified Mercalli Intensity Scale, floor response spectrum, and cumulative fatigue are discussed. The implementation scope on the field-programmable gate array platform of this work is limited to cumulative absolute velocity, peak ground acceleration, and Modified Mercalli Intensity. It can ensure better availability of the plant through integrated decision-making process by automatic assessment of NPP structure, system, and components.

• The Korean Society of Law and Medicine
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• v.13 no.1
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• pp.295-329
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• 2012

A medical malpractice case requires special legal protection, considering its characteristics, such as seriousness and long term effects of its damages, medical information asymmetry between practitioners and patients, and difficulties in realization of liability. Taking the points above into consideration, Medical Malpractice Arbitration Act of 2012(MAA) has legislative intent to protect the rights of the injured from medical malpractice, while protecting the stability of medical practice by providing arbitration as an alternative dispute resolution. However, constitutional review is required for one new scheme of compensation for medical injuries during delivery, which is implemented in MAA of 2012, especially with regard to freedom to exercise occupation, property, equality under the Constitution. Two important aspects are 1. according to the law, absolute liability applies to compensation for damages during delivery without negligence of practitioners; and 2. the practitioner bears some portion of the cost, 30% in the law above. This article aims to analyze this new institution in various aspects of the Constitution, and, as a result, it does not comply with constitutional criteria.

• Nuclear Engineering and Technology
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• v.54 no.4
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• pp.1439-1448
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• 2022

Background: We investigated the feasibility of in vitro radiosensitivity prediction with gene expression using deep learning. Methods: A microarray gene expression of the National Cancer Institute-60 (NCI-60) panel was acquired from the Gene Expression Omnibus. The clonogenic surviving fractions at an absorbed dose of 2 Gy (SF2) from previous publications were used to measure in vitro radiosensitivity. The radiosensitivity prediction model was based on the convolutional neural network. The 6-fold cross-validation (CV) was applied to train and validate the model. Then, the leave-one-out cross-validation (LOOCV) was applied by using the large-errored samples as a validation set, to determine whether the error was from the high bias of the folded CV. The criteria for correct prediction were defined as an absolute error<0.01 or a relative error<10%. Results: Of the 174 triplicated samples of NCI-60, 171 samples were correctly predicted with the folded CV. Through an additional LOOCV, one more sample was correctly predicted, representing a prediction accuracy of 98.85% (172 out of 174 samples). The average relative error and absolute errors of 172 correctly predicted samples were 1.351±1.875% and 0.00596±0.00638, respectively. Conclusion: We demonstrated the feasibility of a deep learning-based in vitro radiosensitivity prediction using gene expression.

• Journal of Gastric Cancer
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• v.16 no.1
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• pp.34-42
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• 2016

Purpose: Early gastric cancer cases that are estimated to meet indications for treatment before endoscopic submucosal resection are often revealed to be out-of-indication after the treatment. We investigated the short-term treatment outcomes in patients with early gastric cancer according to the pretreatment clinical endoscopic submucosal resection indications. Materials and Methods: We retrospectively reviewed the medical records of patients with early gastric cancer that met the pretreatment endoscopic submucosal resection indications, from 2004 to 2011. Curative resection rate and proportion of out-of-indication cases were compared according to the pre-endoscopic submucosal resection indications. Pre-endoscopic submucosal resection factors associated with out-of-indication in the final pathological examination were analyzed. Results: Of 756 cases, 660 had absolute and 96 had expanded pre-endoscopic submucosal resection indications. The curative resection rate was significantly lower in the patients with expanded indications (64.6%) than in those with absolute indications (81.7%; P<0.001). The cases with expanded indications (30.2%) were revealed to be out-of-indication more frequently than the cases with absolute indications (13.8%; P<0.001). Age of >65 years, tumor size of >2 cm, tumor location in the upper-third segment of the stomach, and undifferentiated histological type in pre-endoscopic submucosal resection evaluations were significant risk factors for out-of-indication after endoscopic submucosal resection. Conclusions: Non-curative resection due to out-of-indication occurred in approximately one-third of the early gastric cancer cases that clinically met the expanded indications before endoscopic submucosal resection. The possibility of additional surgery should be empha-sized for patients with early gastric cancers that clinically meet the expanded indications.

• Earthquakes and Structures
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• v.17 no.5
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• pp.511-519
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• 2019

The concrete gravity dam is one of the most important parts of the nation's infrastructure. Besides the benefits, the dam also has some potentially catastrophic disasters related to the life of citizens directly. During the lifetime of service, some degradations in a dam may occur as consequences of operating conditions, environmental aspects and deterioration in materials from natural causes, especially from dynamic loads. Cumulative Absolute Velocity (CAV) plays a key role to assess the operational condition of a structure under seismic hazard. In previous researches, CAV is normally used in Nuclear Power Plant (NPP) fields, but there are no particular criteria or studies that have been made on dam structure. This paper presents a method to calculate the limitation of CAV for the Bohyeonsan Dam in Korea, where the critical Peak Ground Acceleration (PGA) is estimated from twelve sets of selected earthquakes based on High Confidence of Low Probability of Failure (HCLPF). HCLPF point denotes 5% damage probability with 95% confidence level in the fragility curve, and the corresponding PGA expresses the crucial acceleration of this dam. For determining the status of the dam, a 2D finite element model is simulated by ABAQUS. At first, the dam's parameters are optimized by the Minitab tool using the method of Central Composite Design (CCD) for increasing model reliability. Then the Response Surface Methodology (RSM) is used for updating the model and the optimization is implemented from the selected model parameters. Finally, the recorded response of the concrete gravity dam is compared against the results obtained from solving the numerical model for identifying the physical condition of the structure.

• Journal of Korean Society for Geospatial Information Science
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• v.24 no.3
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• pp.29-38
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• 2016

As publicizing of electromagnetic devices such as smart_phone and drone etc. which are relate with geomagnetic direction, and recognition about the importance to space weather effect and their hazards rises up recently, it is required heavily that the study on the effective measurement of geomagnetic declination and geomagnetic field effects of space weather. The purpose of this study is that the investigation of the feasibility of the absolute geomagnetic measurement in a place, where man-made geomagnetic contamination is low or negligible, with replacing the azimuth marks used for the absolute geomagnetic declination measurement with unified control points(UCP) which established at suburb. Further to this, have first derived the correlation of daily variations and disturbance level between the published indices($K_P$ and $K_K$) and geomagnetic element calculated from geomagnetic data of Cheongyang observatory located at the middle stage in Korea and is a member of INTERMAGNET. In addition, have carried out that the absolute measurement for the geomagnetic declination at three places near unified control point and one place with wide open field in Korea. The world magnetic models(WMMs) are selected as the criteria for comparison on the feasibility of geomagnetic declination investigation near unified control points. We compared deviations of declination from absolute measurement with that obtained from WMMs, also those from WMMs inter-comparison. The result through examination and analysis show that the feasibility of the absolute geomagnetic declination measurement with replacing the azimuth marks with UCP which established at suburb is possible.

• Journal of the Korean Society for Library and Information Science
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• v.13
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• pp.95-119
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• 1986

The objective of this study is to search for a theoretical and practical solution to the question of what is the most effective and qualitative method of information service for the college and university libraries in Korea. Assuming the maximum service or total service theory in information services, therefore, it appears natural that the subject specialist who is highly knowledgeable in his subject is indispensable in raising the quality of information librarians. The procedure of this research was as follows: There was no college and university library employing any full-time subject spceialist in Korea. This research, however, was proceeded on the assumption that subject specialists are already employed in all of the college and university libraries after the subject specialist system is established. The least qualification of subject specialist is limited, based on the criteria given by the foreign literature, to those who have master's degree in Library Science and bachelor's degree in any other subject area, those who have bacholor's degree in Library Science and master's degree in any other subject area, or those who have both bacholor's and master's degrees in Library Science with minor in any subject field . To prove the research hypothesis that the subject specialist will perform his role more efficiently than the generalist in effectively providing information service based on both accuracy and speed, this research as an obtrusive testing method analyzed the effectiveness by presenting information questions to the generalists and subject specialists who are information librarians in college and university libraries. For this study 20 librarians working at 12 university libraries were tested for performance levels of information services. The result showed $59.75\%$ an absolute performance rate and $75.20\%$ an adjust performance rate. Compared to Thomas Childer's 1970 study in which he used the unobtrusive testing method, these results were $5\%$ higher in the absolute performance rate and $11.36\%$ higher in the adjust performance rate. In comparing the generalist with the subject specialist in efficiency of information service, while the absolute performance rate was $57.08\%$ and the adjust performance rate was $73.08\%$ in the case of the generalist, the absolute rate was $63.75\%$ and the adjust rate was $78.38\%$ in the case of specialist, therefore, the efficiency of the subject specialist was $6.67\%$ higher in the absolute performance rate and $5.30\%$ higher in the adjust performance rate than that of generalist. But the factor of speediness was excluded from the analysis because of the difference between the time the interviewers recorded and the time the interviewee recorded. On the basis of the result of this research, it should be desirable to educate subject specialists and employ them as information librarians and for them to function as efficient subject specialists in order to improve the effectiveness of information services, the nucleus of the raison d'etre of college and university libraries.