• 한국임상수의학회지
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• 제34권6호
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• pp.420-424
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• 2017

Cystic endometrial hyperplasia (CEH) and uterine dilation (hydro-, muco-, hemato- and pyometra) are common uterine diseases in intact female dogs. The aim of the present study was to assess the usefulness of digital abdominal radiography in diagnosing uterine disease in intact female dogs. Two hundred and thirteen intact female dogs were included, and were classified into four groups on the basis of radiographic uterine visibility (visible/invisible) and ultrasonographic findings (normal uterus/abnormal uterine condition including CEH and uterine dilation). For each dog, the ratio of the maximum uterine diameter to the height of the fifth lumbar vertebral body (U/L5 ratio) was calculated on radiographs. There were 78 and 135 dogs in the normal and abnormal groups, respectively; 34.6% normal and 53.5% abnormal uteri were visible on abdominal radiographs. Our results suggested that a mean U/L5 ratio of $1.18{\pm}0.53$ ($mean{\pm}2SD$) indicated a normal radiographic uterus diameter, and that a value of > 1.60 should be used as an indicator of uterine disease in clinical practice. However, because false negative results were noted, radiography cannot replace ultrasonography for assessment of the uterus.

• 대한두경부종양학회지
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• 제34권2호
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• pp.29-34
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• 2018

Background/Objectives: The aim of this study was to investigate the diagnostic value of i-scan in the differential diagnosis of oral cavity leukoplakia based on visualization of abnormal vascular features. Materials & Methods: Thirty- one patients with oral cavity leukoplakia were enrolled in the study. Images of their oral cavity obtained using conventional white light endoscopy and an i-scan-enhanced endoscopy (Pentax DEFINA EPK-3000 Video Processors, with Pentax VNLJ10) were reviewed. The microvascular features of the lesions and vascular changes were analyzed and the results were compared with the histopathologic diagnosis. Results: Among the 31 oral cavity leukoplakia patients, 8 (25.8%) patients revealed hyperkeratosis, 10 (31.2%) low-grade dysplasia, 5 (16.2%) high-grade dysplasia and 8 (25.8%) invasive squamous cell carcinoma on histopathologic examination. Using i-scan-enhanced endoscopy, we could found abnormal vascular change with neoplastic neoangiogenesis in most high-grade dysplasia or invasive cancer in oral cavity. (high-grade dysplasia: 4/5 [80.0%], and invasive squamous cell carcinoma: 7/8 [87.5%]). Conclusion: i-scan-enhanced endoscopy could be a useful optical technique for the diagnosis of oral cavity leukoplakia. Our results suggest that i-scan may be a promising diagnostic tool in the early detection of suspected oral mucosal lesion.

• Nuclear Engineering and Technology
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• 제48권5호
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• pp.1280-1290
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• 2016

This paper presents an advanced estimation method for obtaining the probability density functions of a damage parameter for valve leakage detection in a reciprocating pump. The estimation method is based on a comparison of model data which are simulated by using a mathematical model, and experimental data which are measured on the inside and outside of the reciprocating pump in operation. The mathematical model, which is simplified and extended on the basis of previous models, describes not only the normal state of the pump, but also its abnormal state caused by valve leakage. The pressure in the cylinder is expressed as a function of the crankshaft angle, and an additional volume flow rate due to the valve leakage is quantified by a damage parameter in the mathematical model. The change in the cylinder pressure profiles due to the suction valve leakage is noticeable in the compression and expansion modes of the pump. The damage parameter value over 300 cycles is calculated in two ways, considering advance or delay in the opening and closing angles of the discharge valves. The probability density functions of the damage parameter are compared for diagnosis and prognosis on the basis of the probabilistic features of valve leakage.

• Journal of Biosystems Engineering
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• 제15권1호
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• pp.23-32
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• 1990

Geometrical characteristics of fruit including perimeter, projected area and length of minor and major axis were calculated by computer programs to be used in fruit sorting by image processing system. The results are summerized as follows. 1. A program calculating perimeter, projected area, and length of minor and major axis by edge detection and chain code was developed. 2. Geometrical characteristics of given figures were calculated to verify the program and the discrepancies from the measured values were about 5%. 3. Regression models for estimating volums of apples were developed and regression coefficients for each variety were found. 4. Abnormal apples could be recognized by comparing the ratio of minor axis to major axis and the standard value was proposed.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2019년도 전력전자학술대회
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• pp.416-417
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• 2019

In this paper, an effective power flow control strategy (PFCS) based on the centralized control approach and a DC-link (DCV) restoration algorithm for DC microgrid (DCMG) are presented. By investigating the statuses of system power units, eleven operating modes are given to ensure the system power balance under various conditions. To avoid the system power imbalance caused by the delay of grid fault detection, a reliable DCV restoration algorithm is proposed. In the proposed scheme, when an abnormal variation of the DCV is detected, the battery instantly starts a local emergency control mode to restore the DCV to the nominal value regardless of the control mode from the central controller. The simulations and experiments are carried out to prove the effectiveness of the PFCS and the proposed DCV restoration algorithm.

• 대한전자공학회논문지SP
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• 제38권6호
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• pp.721-734
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• 2001

제안된 연구는 유방촬영영상(Mammogram)에서 종양의 추출에 관한 연구로서, 맘모그램의 특성을 파악하여 종양에 대한 자동적인 추출을 시행하였다. 처리과정에서 동질성 특성을 이용하여 정상조직인 Cooper's ligament로부터 종양조직을 분리하였고 고밀도 후보에 대한 처리방법으로 다중 문턱값 적용방식을 사용하였다. 추출된 부분을 8-연결성 관계를 사용하여 1차 후보를 추출하였다. 1차 추출된 각 후보에 대하여 명암값을 지형적 높이정보로 해석한 이분화영상으로 표현하여 이중원형성과 분포 비율을 비교하는 방법을 통하여 2차 후보 추출을 시행하였다. 최종적인 종양의 결정은 공간원형성 판단을 위한 반구 형태의 템플리트를 생성하여 비교하는 방법을 이용하여 후보에 대한 순위를 결정하였다. 알고리즘을 실제 종양이 확진된 환자의 136 예에 적용하여 추출된 결과와 전문의가 지적한 결과를 비교하여 93.38%의 민감도를 얻었으며, 최종추출 단계에서는 124 예에서 1 순위로 종양을 추출하여 97.63%의 FP(False positive)의 결과를 나타냈다.

• 한국안전학회지
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• 제31권6호
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• pp.121-128
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• 2016

Social Media transformed the mass media based information traffic, and it has become a key resource for finding value in enterprises and public institutions. Particularly, in regards to disaster management, the necessity for public participation policy development through the use of social media is emphasized. National Disaster Management Research Institute developed the Social Big Board, which is a system that monitors social Big Data in real time for purposes of implementing social media disaster management. Social Big Board collects a daily average of 36 million tweets in Korean in real time and automatically filters disaster safety related tweets. The filtered tweets are then automatically categorized into 71 disaster safety types. This real time tweet monitoring system provides various information and insights based on the tweets, such as disaster issues, tweet frequency by region, original tweets, etc. The purpose of using this system is to take advantage of the potential benefits of social media in relations to disaster management. It is a first step towards disaster management that communicates with the people that allows us to hear the voice of the people concerning disaster issues and also understand their emotions at the same time. In this paper, Korean language text mining based Social Big Board will be briefly introduced, and disaster issue detection model, which is key algorithms, will be described. Disaster issues are divided into two categories: potential issues, which refers to abnormal signs prior to disaster events, and occurrence issues, which is a notification of disaster events. The detection models of these two categories are defined and the performance of the models are compared and evaluated.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3385-3390
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• 2016

Background: Sequential use of circulating prostate cell (CPC) detection has been reported to potentially decrease the number of unnecessary prostate biopsies in men suspected of prostate cancer. In order to determine the real world effectiveness of the test, we present a prospective study of men referred to two hospitals from primary care physicians, one using CPC detection to determine the necessity of prostate biopsy the other not doing so. Materials and Methods: Men with a suspicion of prostate cancer because of elevated PSA >4.0ng/ml or abnormal DRE were referred to Hospitals A or B. In Hospital A all underwent 12 core TRUS biopsy, in Hospital B only men CPC (+), with mononuclear cells obtained by differential gel centrifugation identified using double immunomarking with anti-PSA and anti-P504S, were recommended to undergo TRUS biopsy. Biopsies were classifed as cancer or no-cancer. Diagnostic yields were calculated, including the number of posible biopsies that could be avoided and the number of clinically significant cancers that would be missed. Results: Totals of 649 men attended Hospital A, and 552 men attended Hospital B; there were no significant differences in age or serum PSA levels. In Hospital A, 228 (35.1%) men had prostate cancer detected, CPC detection had a sensitivity of 80.7%, a specificity of 88.6%, and a negative predictive value of 89.5%. Some 39/44 men CPC negative with a positive biopsy had low grade small volume tumors. In Hospital B, 316 (57.2%) underwent biopsy. There were no significant differences between populations in terms of CPC and biopsy results. The reduction in the number of biopsies was 40%. Conclusions: The use of sequential CPC testing in the real world gives a clear decision structure for patient management and can reduce the number of biopsies considerably.

• 분석과학
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• 제34권2호
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• pp.78-86
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• 2021

The objective of this study was to investigate urinary cut-off concentrations of quetiapine and risperidone for distinction between normal and abnormal/non-takers who were being placed on probation. Liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was employed for determination of antipsychotic drugs in urine from mentally disordered probationers. The optimal cut-off values of antipsychotic drugs were calculated using receiver operating characteristic (ROC) curve analysis. The sensitivity and specificity of the method for the detection of antipsychotic drugs in urine were subsequently evaluated. The area under the ROC curve (AUC) was 0.927 for norquetiapine and 0.791 for 9-hydroxyrisperidone, respectively. These antipsychotic drugs are classified readily in the ROC curve analysis. The cut-off values for distinguishing regular and irregular/non-takers were 39.1 ng/mL for norquetiapine and 67.9 ng/mL for 9-hydroxyrisperidone, respectively. The results of this study suggest the cut-off values of quetiapine and risperidone were highly useful to distinguish regular takers from irregular/non-takers.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5355-5358
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• 2014

Background: To assess the role of sonographic endometrial thickness and hysteroscopic polyp size in predicting premalignant and malignant polyps in postmenopausal women. Materials and Methods: A total of 328 postmenopausal women with abnormal uterine bleeding and thickened endometrium underwent operative hysteroscopy due to detection of endometrial polyps were included in this retrospective study. Preoperative endometrial thickness measured by transvaginal ultrasonography and polyp size on hysteroscopy were noted. Hysteroscopic resection with histology was performed for endometrial polyps. Endometrial thickness and polyp size were evaluated on the basis of final diagnosis established by histologic examination. Receiver operator characteristic curves were calculated to assess the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of endometrial thickness and polyp size for detecting pemalignant and malignant polyps. Results: Premalignant and malignant polyps were identified in 26 (7.9%) of cases. Sonographic measurement showed a greater endometrial thickness in cases of premalignant and malignant polyps when compared to benign polyps. On surgical hysteroscopy, premalignant and malignant polyps were also larger. Endometrial thickness demonstrated a sensitivity of 53.8%, specificity of 85.8%, PPV of 24.6% and NPV of 95.6% at a cut-off limit of 11.5 mm with diagnostic accuracy of 83.2%. Polyp size has a diagnostic accuracy of 94.8% with a sensitivity of 92.3%, specificity of 95.0%, PPV of 61.5% and NPV of 99.3% at a cut-off point of 19.5mm. Conclusions: Endometrial thickness measured by transvaginal ultrasonography is not sufficient in predicting premalignant and malignant endometrial polyps in postmenopausal women with abnormal uterine bleeding and thickened endometrium. Polyp size on hysteroscopy is a more accurate parameter, because of better sensitivity and specificity. However, while polyp size ${\geq}19.5mm$ seems to have a great accuracy for predicting premalignancy and malignancy, histologic evaluation is still necessary to exclude premalignant and malignant polyps.