• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.12
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• pp.99-108
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• 2015

The embedded microcontroller which is operated by the logic gates synchronized on the clock pulse, is gradually used as main controller of mission-critical systems. Severe electrical situations such as high voltage/frequency surge may cause malfunctioning of the clock source. The tolerant system operation is required against the various external electric noise and means the robust design technique is becoming more important issue in system clock failure problems. In this paper, we propose on-chip backup clock change architecture for the automatic clock failure detection. For the this, we adopt the edge detector, noise canceller logic and glitch-free clock changer circuit. The implemented edge detector unit detects the abnormal low-frequency of the clock source and the delay chain circuit of the clock pulse by the noise canceller can cancel out the glitch clock. The externally invalid clock source by detecting the emergency status will be switched to back-up clock source by glitch-free clock changer circuit. The proposed circuits are evaluated by Verilog simulation and the fabricated IC is validated by using test equipment electrical field radiation noise

• Journal of Korean Neurosurgical Society
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• v.63 no.6
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• pp.821-826
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• 2020

Objective : Hyperostosis in meningiomas can be present in 4.5% to 44% of cases. Radical resection should include aggressive removal of invaded bone. It is not clear however to what extent bone removal should be carried to achieve pathologically free margins, especially that in many cases, there is a T2 hyperintense signal that extends beyond the hyperostotic bone. In this study we try to investigate the perimeter of tumour cells outside the visible nidus of hyperostotic bone and to what extent they are present outside this nidus. This would serve as an initial step for setting guidelines on dealing with hyperostosis in meningioma surgery. Methods : This is a prospective case series that included 14 patients with convexity meningiomas and hyperostosis during the period from March 2017 to August 2018 in two university hospitals. Patients demographics, clinical, imaging characteristics, intraoperative and postoperative data were collected and analysed. In all cases, all visible abnormal bone was excised bearing in mind to also include the hyperintense diploe in magnetic resonance imaging (MRI) T2 weighted images after careful preoperative assessment. To examine bony tumour invasion, five marked bone biopsies were taken from the craniotomy flap for histopathological examinations. These include one from the centre of hyperostotic nidus and the other four from the corners at a 2-cm distance from the margin of the nidus. Results : Our study included five males (35.7%) and nine females (64.3%) with a mean age of 43.75 years (33-55). Tumor site was parietal in seven cases (50%), fronto-parietal in three cases (21.4%), parieto-occipital in two cases (14.2%), frontal region in one case and bicoronal (midline) in one case. Tumour pathology revealed a World Health Organization (WHO) grade I in seven cases (50%), atypical meningioma (WHO II) in five cases (35.7%) and anaplastic meningioma (WHO III) in two cases (14.2%). In all grade I and II meningiomas, bone biopsies harvested from the nidus revealed infiltration with tumour cells while all other bone biopsies from the four corners (2 cm from nidus) were free. In cases of anaplastic meningiomas, all five biopsies were positive for tumour cells. Conclusion : Removal of the gross epicentre of hyperostotic bone with the surrounding 2 cm is adequate to ensure radical excision and free bone margins in grade I and II meningiomas. Hyperintense signal change in MRI T2 weighted images, even beyond visible hypersototic areas, doesn't necessarily represent tumour invasion.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.9 no.5
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• pp.1045-1051
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• 2005

We developed an orofacial pains diagnosis/therapy system which can enlarge a therapy effect through a new stimulation. Contrary to its established method, this therapy system(DDTS-1) is a treating method which absorbs a surplus ion charge- the cause of an outbreak of a pain-of the human body using a capacitor. Absorbing a surplus ion charge of the human body with effect, it obtained optimal parameters which is control signal to control charging/discharging a capacitor to be 6Hz, and capacitance to be $0.1\~0.33{\mu}F.$ Through clinical demonstration, experimented on among patients-namely dental pain patients, joint disorders patients, and trigeminal neuralgia patients to verification of system. In result, an EAST stimulater had a very low change of abnormal potential against normal potential before/after being placed under medical care. DDTS-1 showed obvious differences that two potentials are one and the same potential or one potential is similar to the other one. DDTS-1 comparing with EAST showed the remedial value of the comparative advantage in all the medical treatment of pains. Therefore, stimulation of DDTS-1 is more effective than the existing electric stimulation. We verified its validity of ion charge absorption in the human body using capacitor which presented the present thesis. That is, we verified theoretical adequacy of control action in a pain, and its efficiency as well as confidence.

• Progress in Medical Physics
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• v.10 no.3
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• pp.125-131
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• 1999

T$_1$/T$_2$ weighted images are being used to give the characteristic contrast among the various tissues and the norma;/abnormal tissues. Abnormalities in tissues, in general, accompany the biochemical changes and eventually structural ones in which results in the change in T$_1$ and T$_2$ relaxation times of water protons. It has been suggested that the mapping of T$_1$/T$_2$ values may serve as a possible tool for the quantitative evaluation of the degree of abnormality. On reconstructing T$_1$/T$_2$ maps(or any other MR parametric map), only corresponding variables are to be varied, such as TE for T$_2$, TI or TR for T$_1$ and b-factor for diffusion images. But often the receiver gain is taken for the optimal usage of A/D converter, so that the set of the image data has different receiver gain. It must be corrected before any attempt to reconstruct the maps. Here we developed method of correcting receiver gain variation effect, using the standard deviation of noise on individual image. The resultant T$_1$ and T$_2$ values were very comparable to the other reported values.

• Journal of Korean Society for Geospatial Information Science
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• v.15 no.1 s.39
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• pp.39-46
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• 2007

Most areas in Kangwon Province are mountainous and vulnerable to landslide due to the rainy season in summer and the localized torrential downpour triggered by abnormal climate. In particular, the rainfall is one of direct reasons for landslide. In accordance with the analysis of the relevance between the landslide areas and the accumulated rainfall for four months, there are severe damages of landslide to the areas having more than 1,100 mm of rainfall during three(3) months. Further, it indicates that the more the accumulated rainfall is the greater the size of landslide. These analyses show that the rainfall causes the possible and potential landslide in the vulnerable areas. And also, it means that there exist strong possibilities of landslide even in the areas of lower vulnerability if the amount of rainfall is above certain standard level. Accordingly, in this study we stored the GIS database on the causes and factors of landslide in the southern parts of Kangwon province and conducted simulations on the change of distribution of vulnerable areas by varying the rainfall conditions and by using the evaluation data of landslide vulnerability. As such a result, we found that the landslide could potentially occur if the amount of rainfall is 200 mm and more.

• Journal of Korean Ophthalmic Optics Society
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• v.17 no.3
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• pp.285-291
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• 2012

Purpose: This study was conducted to research any effect on visual function related to accommodation by VDT work. Methods: The refraction power, accommodative lag, accommodative facility, relative accommodation, amplitude of accommodation and blink rate were measured before and after VDT work for 2 hours on 48 university students (16 males and 32 females), without abnormal accommodative function and systemic and ocular disease, who had never undergone corrective eye surgery. All examinations were performed with distant refraction, and a survey was conducted on the items related to subjective symptoms of VDT syndrome. Results: After 2 hours of VDT work, refractive power increased by 0.23 D, the amount of change in accommodative lag were $0.17{\pm}0.42D$ in the right eye and $0.23{\pm}0.47D$ in the left eye (t=2.26, p=0.03). There were statistically significant differences. Both the accommodative facility and relative accommodation and amplitude of accommodation were decreased after work. However, blink rate were increased. After VDT work, 33.4% of the subjects showed subjective symptoms of asthenopia and 33.3% of them showed shoulder pain. Conclusions: As a result, the accommodative lag increased in response to the two hours of VDT work, and overall accommodative functions were decreased. In addition, as symptoms of providing visual strain, asthenopia showed the most prominent subjective symptoms.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.27 no.5
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• pp.315-323
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• 2015

Damage level of coastal structures has been scaled up according to increase of wave height and duration of the storm due to the abnormal global climate change. So, the design criteria for new breakwaters is being intensified and structural strengthening is also conducted for the existing breakwaters. Recently, interlocking concept has been much attention to enhance the structural stability of the conventional caisson structure designed individually to resist waves. The interlocking caisson breakwater may be survival even if unusual high wave occurs because the maximum wave force may be reduced by phase lags among the wave forces acting on each caisson. In this study, the dispersion characteristics of wave forces using interlocking system that connect the upper part of caisson with cable in the normal direction of breakwater was investigated. A simplified linear model was developed for computational efficiency, in which the foundation and connection cables were modelled as linear springs, and caisson structures were assumed to be rigid. From numerical experiments, it can be found that the higher wave forces are transmitted through the cable as the angle of incident wave is larger, and the larger the stiffness of the interlocking cable makes larger wave dispersion effect.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.29 no.4
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• pp.180-188
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• 2017

Recently, as the strength of winds and waves increases due to the climate change, abnormal waves such as swells have been also increased, which results in the increase of downtime events of loading/unloading in a harbour. To reduce the downtime events, breakwaters were constructed in a harbour to improve the tranquility. However, it is also important and useful for efficient port operation by predicting accurately and also quickly the downtime events when the harbour operation is in a limiting condition. In this study, numerical simulations were carried out to calculate the wave conditions based on the forecasted wind data in offshore area/outside harbour and also the long-term observation was carried out to obtain the wave data in a harbour. A forecasting method was designed using an auto-regressive (AR) and artificial neural networks (ANN) models in order to establish the relationship between the wave conditions calculated by wave model (SWAN) in offshore area and observed ones in a harbour. To evaluate the applicability of the proposed method, this method was applied to predict wave heights in a harbour and to forecast the downtime events in Pohang New Harbour with highly complex topography were compared. From the verification study, it was observed that the ANN model was more accurate than the AR model.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.19 no.3
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• pp.249-256
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• 1986

The carp (Cyprinus carpio) used in the experiment were hatched in the spring this year and reared to 5.96g($4.84{\sim}6.55g$) in mean weight in a nursery pond at Daeyon fish farm, Pusan, Korea. The sample fish were exposed to different conditions of total ammonia (TA-N) concentrations 10, 20 and 30ppm and pH 6.5, 7.0, 7.5 and 8.0 at water temperatures 20, 25 and $30^{\circ}C$ for 24, 48 and 72 hours. After the procedure, the gill, liver and kidney of the fish were examined histopathologically. In this experiment, with the rise of water temperature, increase of pH and ammonia concentration, and the extension of exposure time the three organs showed the tendency of apparent abnormal changes such as hypertrophy and necrosis in their tissues. At $20^{\circ}C$ of water temperature gill tissue did not show any abnormality regardless of the change of pH at 10 ppm of ammonia concentration for 24 hours of exposure, but beyond the conditions given above, there occurred hypertrophy and the epithelium of gill lamellae was detached. The detach of gill lamellae epithelium initiated from the proximal part of the gill lamellae then gradually spread toward the uppermost tip. The heavier vacuolation of the liver was observed with the rise of water temperature and pH, and such morbid state in the liver was considered to be the result of edema in the liver tissue. The kidney showed no damage to the renal tubule epithelium at pH 6.5, but it was damaged at pH 8.0 when exposed to 30 ppm ammonia at $20^{\circ}C$ for 24 hours.

• Applied Microscopy
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• v.27 no.2
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• pp.197-215
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• 1997

A morphologic study on the effect of butylated hydroxytoluene (BHT) on experimental hepatocarcinogenesis induced by 3'-methyl-4-dimethyl aminoazobenzene (3'-MeDAB) was investigated. A total of 110 Sprague-Dowley male rats weighting about 200 g each were used for the experiment, and divided into 4 groups; the 3'-MeDAB, BHT, 3'-MeDAB/BHT treated group, and the control group. Four to eight rats of each group were sacrified on the 4th, 8th, 14th and 16th experimental weeks, with continuous pelletized feeding containing 0.09% 3'-MeDAB and 0.5% BHT. The liver was examined by transmission and scanning electron microscopy. The results were as follows; Electron microscopically, the fine structure of the hepatocytes remained consistently abnormal up to 16 weeks after the 3'-MeDAB treatment. There was no significant difference in the groups observed earlier than in the ones observed later. Many subcellular changes were observed : nuclear change, decreased glycogen, mitochondrial abnormalities, disaggregated rough endoplasmic reticulum, marked proliferation of smooth endoplasmic reticulum, dilatation and distortion of bile canaliculi, increased lysosomes, apoptotic bodies, migration of bile ductule cell. In the BHT treated group, the ultrastructural changes of hepatocytes were not significant, except for the lipid droplets and proliferated smooth endoplasmic reticulum among hepatocytes depending on the experimental duration. The various subcellular changes of 3'-MeDAB/BHT treated groups were simillar to those of the 3'-MeDAB treated group, but the degree of changes in the 3'-MeDAB/ BHT treated group decreased compared with those of the 3'-MeDAB treated group. These results suggest that dietary butylated hydroxytoluene has a protective/inhibitory effect on the hepatocarcinogenesis induced by 3'-methyl-4-dimethyl -aminoazobenzene.