• 제목/요약/키워드: Abnormal change

검색결과 726건 처리시간 0.035초

Clinical Features and Long-Term Outcome in Adult Stroke Patient due to Moyamoya Disease : A Single Subject Study

  • Kwon, Yong Hyun;Kim, Chung Sun
    • The Journal of Korean Physical Therapy
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    • 제25권3호
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    • pp.126-131
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    • 2013
  • This case report described a single case of adult stoke patient due to Moyamoya disease through long-term follow-up observation, which included his demographics, brain images, and change of motor function and functional activities. The subject was the 54-year-old male diagnosed with left hemiparesis from a stroke due to multifocal encephalomalacia in both hemispheres. At the time of the stroke attack, he took brain surgery intervention including external ventricular drain. Physical and occupational therapy for stroke rehabilitation were admitted including muscle strengthening exercises, functional activity/ADL training, neurofacilitative techniques with bobath or proprioceptive neuromuscular facilitation concepts, and compensatory strategy. Patient's MRI showed that right frontal lobe, right peri-ventricular area, left parietal, and left occipital lobes were damaged, and MRA showed that abnormal collateral vessel was richly developed in both hemispheres by occlusion of proximal internal carotid arteries in both sides. His motor strength was improved from poor to good grade in all of upper and lower limb motions, that MBC was improved from stage 1 to stage 5. In FAC and barthel index, at the initial evaluation, he could not perform any functional movement, but his FAC and barthel index were on 3 and 14 points at present, respectively. During long-term follow-up for approximately 4 years, the subject's functional motor ability was improved, as similar with recovery progression of usual stroke patient. We believe that this single case report will provide clinical information and concern regarding Moyamoya disease with physical therapist, in terms of such as epidemiology, pathogenesis, diagnostic procedures, clinical features, recovery process, and prognosis.

두부진전을 주증상으로 내원한 심인성 진전 환자 치험례 (A Case Report of Psychogenic Tremor Patient with Head Tremor)

  • 황은영;정선용;김종우
    • 동의신경정신과학회지
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    • 제21권3호
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    • pp.95-103
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    • 2010
  • 가족 간의 갈등으로 인해 발생한 두부진전이 4-5년간 지속된 환자에게 한약물과 한방정신요법을 시행하여 증상의 유발과 악화인자에 대한 통찰을 하고 조절할 수 있는 통제력을 가지게하여 증상을 완화되었고, 수개월이 지난 지금까지 호전상태가 지속되는 것을 경험하였다. 심인성 운동장애는 전체 운동장애 중 2-3% 정도로 드물게 일어나며, 진전이 가장 흔한 형태이기는 하나 상하지에 많이 발생하고, 두부에만 국한적으로 일어나는 경우는 드물다. 이에 상기 증례는 다른 신경학적 증상을 동반하지 않고 두부에만 국한적으로 진전이 발생한 환자에게 한의학적 치료를 하여 유효한 결과를 얻었기에 보고하는 바이다.

GST 추출물의 유전독성평가 (Genotoxicity Study of GST Extract)

  • 이철화;한종민;이미영;정인철;진미림;김승형;박양춘
    • 동의생리병리학회지
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    • 제28권6호
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    • pp.621-629
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    • 2014
  • This study aimed to evaluate the genotoxicity of GST (Gamisasangja-tang). For examining genotoxicity, we carried out bacterial reverse mutation assay, chromosome aberration assay, micronucleus induction test according to OECD guidelines. Bacterial reverse mutation assay: In GST treating group, regardless of existence S9 mix, revertant colonies counts appeared to be less than twice of negative control group and dose dependent increase. In positive control group, revertant colonies counts were shown to be more than twice of negative control croup. Chromosome aberration assay: All cell line showed repetition rate of abnormal chromosome aberration less than 5%, regardless of treating time, existence of S9 mix, and no significant change ($p{\succeq}0.05$) compared with negative control group. Micronucleus induction test: Micronucleated polychromatic erythrocytes (MNPCE) repetition rate of Polychromatic erythrocytes (PCE) showed no significant changes compared with negative control group ($p{\succeq}0.05$). PCE portion of total erythrocytes also showed no significant changes ($p{\succeq}0.05$). Our results showed that GST didn't induce any genotoxicity.

Hormonal Requirements Induced Different Regeneration Pathways in Alhagi graecorum

  • Hassanein, A.M.
    • Journal of Plant Biotechnology
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    • 제6권3호
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    • pp.171-179
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    • 2004
  • Hormonal requirements inducing different regeneration pathways with particular emphasis on somatic embryo-genesis in Alhagi graecorum were studied. While combination of 0.5 $\mu{M}$ 2,4-dichlorophenoxyacetic acid (2,4-D), 2.5 $\mu{M}$ 6-benzylaminopurine (BAP) and 5 $\mu{M}$ 1-naphthaleneacetic acid (NAA) in MS medium induced callus formation and callus maintenance from internodal explants, each alone or in combination with other induced distinct regeneration pathway. Adventitious bud formation was induced on MS medium supplemented with 2.5 $\mu{M}$ BAP. It was improved when 2.5 $\mu{M}$ BAP was used in combination with 5 $\mu{M}$ NAA. MS medium containing 0.5 $\mu{M}$ 2,4-D or 5 $\mu{M}$ NAA induced the formation of abnormal direct somatic embryos. While increase of 2,4-D concentration (1.125-9) resulted in the formation of viable embryogenic mass, increase of NAA did not change its effect. NAA should be used in combination with 2,4-D even at low concentration (0.5 $\mu{M}$) to form embryogenic mass. In A. gaecorum, the role of 2,4-D as trigger of somatic embryogenesis and BAP as trigger of adventitious bud formation was deduced, but for maximum yield certain auxin-cytokinin ratio should be applied. Embryogenic masses characterized by high water content, low peroxidase activity, and low number of peroxidase and glutamate oxaloacetate transaminase bands in comparison with calli obtained under conditions stimulating adventitious bud formation. The resulted differential gene expression, which could be detected by native-PAGE patterns, could be used as marker for organogenic pathway in A. graecorum.

Evaluation of Azygos Vein to Aorta Ratio using Multi-Detector Computed Tomography in Dogs

  • Park, Hyunyoung;Kim, Jungyong;Kim, Soochan;Jeong, Woochang;Lee, Jungwoo;Choi, Sooyoung;Choi, Hojung;Lee, Youngwon
    • 한국임상수의학회지
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    • 제37권2호
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    • pp.82-87
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    • 2020
  • The purpose of this study is to evaluate the azygos vein to aorta diameter ratio (AV/AO ratio) in healthy dogs and dogs with diseases that may cause azygos vein dilation. The normal groups included eleven healthy beagle dogs and eleven small breed dogs. The abnormal group included 43 dogs that had diseases with high right atrial pressure (RA group), obstruction of cranial or caudal vena cava (CVC group) and porto-azygos shunt group (PSS group). The diameter of AV and AO were measured at three sites on thoracic CT images; the level of the cranial endplate of 12th thoracic vertebra (TV level), the tracheal bifurcation (TB level) and the insertion to the cranial vena cava (CrVC level). The AV/AO ratio at the CrVC level had significantly higher values than those at the TV and TB levels in the normal groups. The AV/AO ratios of TV and TB levels in the CVC group and the values at all measurement sites of the PSS group were significantly higher than the normal groups. AV/AO ratio will be a useful factor for the evaluation of various clinical conditions that change the AV diameter with respect independent to the body weight in dogs.

전과정평과를 통한 유기농자재의 탄소배출량 산정연구 -유기질비료를 중심으로- (A Study on the Amount of Carbon Emission of Organic Materials through Life-Cycle Assessment (LCA))

  • 윤성이;권혁준
    • 한국유기농업학회지
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    • 제19권1호
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    • pp.23-38
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    • 2011
  • ● The current world is suffering abnormal climate caused by global warming. The main cause of global warming is greenhouse gas such as carbon dioxide. The carbon labeling system and carbon traceability system being pushed ahead in the agricultural sector is the policy for responding to climate change to reduce greenhouse gas emissions. To make this policy more effective and enhanced, the amount of carbon emissions should be calculated based on the kind of crops or the various businesses in the agricultural sector. Therefore, in order to estimate the accurate amount of carbon emissions, it is necessary to establish carbon dioxide emission intensity of various agricultural materials added onto the agriculture, and to calculate the amount of carbon dioxide emission for each crop according to agricultural production. The purpose of this study is to establish the amount of emission, emission per agricultural materials, of agricultural materials being added for crop production as a basic step, and emission intensity which can be used in the future market in order to estimate accurate amount of carbon emission in all the policies being promoted in the agricultural sector. Therefore, in this study, in order to build LCI D/B about organic fertilizers among many organic materials added onto the organic agriculture sector, one leading company in organic fertilizer production was selected and LCA was conducted for this leading company. We had to build the intensity and integrated average concept of intensity upon the two cases once production farmers for their own consumption and farms besides organic fertilizer company were categorized even if it's little amount. But in this study, individually produced organic fertilizers were excluded. Calculated results are following. Carbon emission of mixed expeller cake fertilizer in organic fertilizer was 1,106,966.89kg-$CO^2$ and emission intensity was 0.01606kg-$CO^2$, respectively. Total emission of mixed organic fertilizers was 241,523.2kg-$CO^2$ and emission intensity was 0.01705kg-$CO^2$. And total emission of organic compound fertilizers was 94,592.66kg-$CO^2$ and emission intensity was 0.01769kg-$CO^2$, respectively.

Exploring Flow Characteristics in IPv6: A Comparative Measurement Study with IPv4 for Traffic Monitoring

  • Li, Qiang;Qin, Tao;Guan, Xiaohong;Zheng, Qinghua
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제8권4호
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    • pp.1307-1323
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    • 2014
  • With the exhaustion of global IPv4 addresses, IPv6 technologies have attracted increasing attentions, and have been deployed widely. Meanwhile, new applications running over IPv6 networks will change the traditional traffic characteristics obtained from IPv4 networks. Traditional models obtained from IPv4 cannot be used for IPv6 network monitoring directly and there is a need to investigate those changes. In this paper, we explore the flow features of IPv6 traffic and compare its difference with that of IPv4 traffic from flow level. Firstly, we analyze the differences of the general flow statistical characteristics and users' behavior between IPv4 and IPv6 networks. We find that there are more elephant flows in IPv6, which is critical for traffic engineering. Secondly, we find that there exist many one-way flows both in the IPv4 and IPv6 traffic, which are important information sources for abnormal behavior detection. Finally, in light of the challenges of analyzing massive data of large-scale network monitoring, we propose a group flow model which can greatly reduce the number of flows while capturing the primary traffic features, and perform a comparative measurement analysis of group users' behavior dynamic characteristics. We find there are less sharp changes caused by abnormity compared with IPv4, which shows there are less large-scale malicious activities in IPv6 currently. All the evaluation experiments are carried out based on the traffic traces collected from the Northwest Regional Center of CERNET (China Education and Research Network), and the results reveal the detailed flow characteristics of IPv6, which are useful for traffic management and anomaly detection in IPv6.

잉어(Cyprinus carpio)에서 탁수 노출에 의한 아가미 미세구조 변화와 유전자 확인 (Changes of Gill Structure and Identification of Genes by Muddy Water Exposure in Cyprinus carpio)

  • 신명자;이종은;서을원
    • 생태와환경
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    • 제44권1호
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    • pp.95-101
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    • 2011
  • 본 연구에서는 하상교란으로 인해 발생한 탁수가 잉어 아가미 조직의 미세구조와 유전적 발현에 미치는 영향을 조사하였다. 탁수에 80일간 사육한 잉어 아가미 조직에서는 이차새변의 간격이 불규칙해지고, 곤봉화, 부종, 상피세포의 박리가 나타났으며, 새변사이에는 이물질의 부착이 두드러지게 관찰되었다. 20개의 ACP를 이용하여 대조군과 탁수에 사육한 잉어 아가미 조직에서 발현차이를 보이는 24개의 밴드를 확인하였고, 그 중 탁수에 사육한 잉어 아가미 조직에서 발현이 증가된 것은 17개, 발현이 감소된 것은 7개였다. BLAST search를 이용하여 확인한 결과 이들 중 각각의 유전자를 대표하는 DNA 절편인 unigene 정보가 있는 유전자는 3개였다. 정보가 있는 유전자 중 발현 증가를 보인 것은 calcium transporter 1 (TRPV6) mRNA, macha mRNA for putative puroindoline b protein 및 Efnb3 protein-like 등이었다. 아가미 조직에서 확인된 Efnb3 유전자는 세포 신호전달 과정에 관여하는 단백질들을 암호화하는 유전자로써 장기간의 탁수는 어류에 스트레스로 작용하여 새로운 유전자 발현에 영향을 줄것으로 사료된다.

성토하부 연약지반에서의 과잉간극수압 거동 (Excess Pore Water Pressure Response in Soft Clay under Embankment)

  • Kim, Yun-Tae;Kim, Nak-Kyung
    • 한국지반공학회논문집
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    • 제18권3호
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    • pp.105-112
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    • 2002
  • 성토하부 연약지반에서 상재하중의 변화가 없는 상태에서 과잉간극수압의 증가가 Berthierville와 Olga 지역에서 보고되었다. 이와같은 비정상적인 현상들을 고전적인 압밀이론으로 설명하기는 어렵다. 본 논문은 비선형 점소성모델윽 사용하여 자연점토지반에서 유발되는 간극수압 증가를 설명하였다. 제안된 모델은 Darcy 법칙에 의한 간극수압 소산과 점소성 변형에 의한 간극수압 생성에 대한 복합적인 거동을 모사할 뿐만 아니라 시간 의존적인 점소성 거동과 변형을 속도 의존적인 선행압밀하중 특성을 표현할 수 있다. 수치해석기법을 적용하여 Berthierville각 Olga 지역의 성토과정을 해석하였으며, 수치해석 결과와 계측된 값을 비교한 결과 제안된 비선형 점소성모델볶 사용하여 성토가 끝난 직후 간극수압의 증가현상을 설명할 수 있다.

체성분 분석 변수와 X-선 소견을 근거로 한 비만과 요통의 관계 연구 (The Study on Relation of Obesity and Low Back Pain Based on Body Composition using Segmental Bioelectrical Impedance Analysis and Radiological Parameter)

  • 박지현;홍서영
    • 한방재활의학과학회지
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    • 제19권2호
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    • pp.289-302
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    • 2009
  • Objectives : This study was performed in order to investigate the relation of body composition analysis and radiological parameter(lumbosacral angle, lumbar lordortic angle, lumbar gravity line). Methods : This study was carried out with the data from comprehensive medical testing. 75 subject aged 20-59 performed the segmental bioelectrical impedance analysis, questionnaire. And lumbosacral angle, lumbar lordortic angle and lumbar gravity line were measured in the standing position x-ray. Then we analyzed the data. Results : Low back pain(LBP) prevalence in high obesity index(Body Mass Index(BMI), Percentage of Body Fat(PBF), Waist Hip Ratio(WHR)) group was higher than LBP prevalence in normal obesity index group(p<0.01). In LBP group, lumbosacral angle, lumbar lordortic angle were significantly lager than Non-LBP group(p<0.001). And 75% of LBP group indicated abnormal lumbar gravity line ratio(0.67 < Normal lumbar gravity line ratio <1.00). When it comes to analyze relation between obesity index and radiological parameter, no-significant change was seen. Conclusions : This study carried as following research after the study on relation of obesity, LBP and trunk muscle strength. Results from this investigation showed positive correlation between obesity and LBP prevalence. But obesity index didn't indicate significant correlation with structural changes of lumbar vertebrae. When considering prior research, trunk muscle strength changes were more related to LBP prevelence in obese people. This results are expected to explain causes of LBP in obese group.