• Korean Journal of Computational Design and Engineering
• /
• v.3 no.4
• /
• pp.260-273
• /
• 1998

Standardization for product data has not been well established and many different presentation methods are being used in CAD/CAM industry. In order to accomplish system integration or concurrent engineering in such situation, product data exchanges among heterogeneous system are needed. This paper presents a data exchange system between IGES and STEP (AP 202 and 203). The schemata of those standard data formats are represented in EXPRESS and the relationship between corresponding entities are written in EXPRESS-X. Relationships among Non-geometric entities (such as color and annotations) as well as geometric entities are examined. Because the system implemented in this research uses high-level schema language and mappign language, it can be easily extended to support new data formats.

• Journal of the Korean Society for Precision Engineering
• /
• v.16 no.9
• /
• pp.54-61
• /
• 1999

Three dimensional CAD data viewer helps a user to view and use many different types of CAD data without having costly programs that produced them loaded on their computers. A viewer for standard data formats such as STEP and IGES is more useful since most of the CAD systems provide translators for them. We developed a 3D CAD viewer for STEP AP203 solid and assembly data. In addition to the standard shading and assembly tree display, functions for 3D markups and measurement of distance and angles were implemented.

• Korean Journal of Veterinary Research
• /
• v.40 no.2
• /
• pp.283-290
• /
• 2000

The present study was carried out to investigate the blood markers of Cheju horses. The blood protein types (biochemical polymorphism) were tested from 73 Cheju native horses (CNH) and 118 Cheju racehorses(CRH) by horizontal polyacrylamide gel electrophoresis (HPAGE), isoelectric focusing (IEF) and starch gel electrophoresis (SGE). At the same time, their phenotypes and gene frequencies were studied. The biochemical polymorphism phenotypes observed with high frequency were A1B-KK(97.3%), ALB-AB(49.3%), AP-SS(100%), ES-II(30.1%), GC-FF(87.7%), HB-BIBI(49.3%), TF-F2R(41.1%), TF-EF2(8.2%), PGD-FF(97.3%), PGM-SS(50.7%), GPI-II(74.0%) in CNH, While A1B-KK(99.2%), ALB-BB(50.8%), AP-SS(99.2%), ES-II(42.4%), ES-IS(14.4%), GC-FF(95.8%), HBB-IB II(39.8%), TF-F2R(21.2%), PGD-FF(77.1%), PGD-SS(4.3%), PGM-SS(72.9%), GPI-II(90.7%) in CRH. Alleles observed with high frequency were $AlB^{K}$(0.986), $ALB^{B}$(0.616), $AP^{S}$(1.000), $ES^{I}$(0.479), $ES^{F}$(0.274), $GC^{F}$(0.938), $GPI^{I}$(0.856), $HB^{BI}$(0.685), $PGD^{F}$(0.993), $PGM^{S}$(0.753), $TF^{F2}$(0.404), $TF^{R}$(0.397) in CNH and $AlB^{K}$(0.996), $ALB^{B}$(0.720), $AP^{S}$(0.996), $ES^{I}$(0.661), $ES^{F}$(0.203), $GC^{F}$(0.979), $GPI^{I}$(0.936), $HB^{BI}$(0.534), $PGD^{F}$(0.864), $PGM^{S}$(0.852), $TF^{F2}$(0.428), $TF^{R}$(0.272) in CRH. $TF^{E}$(0.041) allele and silent gene($ES^{I{^*}}$ : 0.014) were observed in CNH. The mean heterozygosity in CNH and CRH was observed 0.2974 and 0.2864, respectively.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.19 no.1
• /
• pp.196-203
• /
• 2005

Gunggui-tang has been used for the therapy of blood disorders in Hangbang medicine for long time. Also, Glycyrrhiza uralensis has been used for deficientblood patterns with an irregular pulse or palpitations, coughing and wheezing, and heat or cold in the lungs. Melanogenesis is a physiological process resulting in the synthesis of melanin pigments. We investigated whether the water extract of Gunggui-tang plus G. uralensis inhibited melanogenesis in B16 melanoma cells. Because the molecular events connecting the regulation in tyrosinase activity remain to be elucidated, we also aimed to determine whether Gunggui-tang gamibang(GTG) affects tyrosinase at the gene activation level in the cells. First, we showed that GTG inhibited the tyrosinase promoter activity and further, down-regulated the tyrosinase protein activity in ${\alpha}-melanocyte-stimulating$ hormone $({\alpha}-MSH)-treated$ B16 melanoma cells. GTG also resulted in a decrease of melanin content in MSH-induced melanogenesis, indicating that GTG may be a useful drug in studying the regulation of melanogenesis. The pretreatment of GTG significantly prevented phosphotransferase activity of c-Jun N-terminal kinase (JNK1) and transcriptional activation of activating protein-1 (AP-1) in MSH-treated B16 melanoma cells. These findings indicate that GTG inhibits melanogenesis of B16 melanoma cells via suppression of phosphotransferase activity of JNK1 and transcriptional activation of AP-1.

• Elastomers and Composites
• /
• v.22 no.3
• /
• pp.195-203
• /
• 1987

In this study, as one of the developing ways of the functional elastomer, improvement of the functionality of CB-BR was attempted through moisture curing reaction. The curing reaction of CB-BR was determined with an use of 3-aminopropyltriethoxysilane(APS) as a crosslinking agent, also a solution reaction with an active chlorine of CB-BR was elucidated by using a reaction kinetics theory and a study of physical property was made through moisture curing on the compound of 3-aminopropyltriethoxysilane and CB-BR The results of this study obtained are as follows : 1) CB-BR reacted easily with APS in the liquid state and the reaction rate coefficient and activation energy were as follows : 2) Optimum pressure condition of moisture cured elastomer(CB-BR+APS) was 20 minutes at $150^{\circ}C$, and the crosslinked elastomer was close to the theoretical value (q=1) for Flory's equation($\frac{\alpha}{\alpha-1}=q{\nu}RT$)

• Korean Journal of Computational Design and Engineering
• /
• v.18 no.1
• /
• pp.71-82
• /
• 2013

To modify product design easily, modern CAD systems adopt the feature-based model as their primary representation. On the other hand, the boundary representation (B-rep) model is used as their secondary representation. IGES and STEP AP203 edition 1 are the representative standard formats for the exchange of CAD files. Unfortunately, both of them only support the B-rep model. As a result, feature data are lost during the CAD file exchange based on these standards. Loss of feature data causes the difficulty of CAD model modification and prevents the transfer of design intent. To resolve this problem, a tool for recognizing design features from a B-rep model and then reconstructing a feature-based model with the recognized features should be developed. As the first part of this research, this paper presents a method for decomposing a B-rep model into simple volumes suitable for design feature recognition. The results of experiments with a prototype system are analyzed. From the analysis, future research issues are suggested.

• Natural Product Sciences
• /
• v.15 no.3
• /
• pp.156-161
• /
• 2009

Rubus coreanus, commonly known as 'red raspberry' is used as a traditional oriental medicine in Korea for the management of diseases such as impotence, spermatorrhea and athsma, and for allergies, in combination with other herbal preparations, in many centuries. We undertook a comparison of the hepatoprotective effect of ethanol extracts of the unripe (UREx) and ripe (RREx) R. coreanus extract against acetaminophen (AAP) induced hepatotoxicity in rats. UREx reduced the elevated alanine aminotransferase (ALP), aspartate aminotransferase (AST), total bilirubin (TB), alkaline phosphatase (AP), lipid peroxide and nitric oxide content which had been increased by AAP administration. UREx also increased the cellular glutathione (GSH) content and induced the glutathione-S-transferase (GST), glutathione peroxidase (GSH-Px) content which had been decreased by AAP. RREx did not exhibit strong hepatoprotective effect or antioxidant activity under the same conditions. The experimental results show that the degree of the ripening of R. coreanus affects the hepatoprotective activity in the AAP-intoxicated rats. These findings of a protective mechanism are supportive evidence for the utility of unripened R. coreanus in traditional medicine for liver ailments.

• Korean Journal of Computational Design and Engineering
• /
• v.5 no.1
• /
• pp.23-32
• /
• 2000

In this paper, we present a Web-enabled product data sharing system for the support of RPD (Rapid Product Development) process by incorporating STEP (STandard for the Exchange of Product model data) with Web technology such as VRML (Virtual Reality Markup Language), SGML (Structured Generalized Markup Language) and Java. Extreme competition makes product life cycle short by incessantly deprecating current products with a brand-new one, and thus urges enterprises to devise a new product faster than ever. In this environment, an RPD process with effective product data sharing system is essential to outstrip competitors by speeding up the development process. However, the diversity of product data schema and heterogeneous systems make it difficult to exchange the product data. We chose STEP as a neutral product data schema and Web as an independent exchange environment to overcome these problems. While implementing our system, we focused on the support of STEP AP 203 UoF (Units of Functionality) views to efficiently employ STEP data models that are maximally normalized, and therefore very cumbersome to handle. Our functionality-oriented UoF view approach can increase users'appreciation since it facilitates the modular usage of STEP data models. This can also enhance the accuracy of product data. We demonstrate that our view approach is applicable to the configuration control of mechanical assemblies.

• Proceedings of the Computational Structural Engineering Institute Conference
• /
• 2003.04a
• /
• pp.313-320
• /
• 2003

The efficient and well organized database is essential for the management of information in every industrial field. In this study, a practical and effective database which can handle 3-D information of steel bridges is built on the basis of a STEP-based data model. The data model of steel bridge information is classified into geometric and non-geometric part and the design information is represented by linking geometric information and life cycle supported non-geometric information. Especially, the shape information is represented by boundary representation method, which is one of the representative methods of solid model information. In this study, ISO/STEP(STandard for the Exchange of product model data) AP203(configuration controlled design) EXPRESS schema is used to represent the shape information of steel bridge. The syntax of EXPRESS schema of developed data model is verified by NIST Expresso - is a tool for parsing and compiling EXPRESS schema. Also, this study verifies the conformance of the data model by applying to the real data of Hannam bridge. Therefore, the constructed database using STEP-based data model of steel bridges can be used effectively in the concurrent engineering point of view with transferring and sharing steel bridge information.

• Transactions of the Korean Society of Mechanical Engineers A
• /
• v.24 no.9 s.180
• /
• pp.2235-2245
• /
• 2000

The necessity of using rapid prototyping(RP) for short-run manufacturing is continuously driving a development of a cost-effective technique that will produce completely-finished quality parts in a very short time. To meet these demands, the improvements in production speed, accuracy, materials, aid cost are crucial. Thus, a new hybrid-RP system performing both deposition and machining in a station is proposed. For the new hybrid RP process to maintain the same degree of process automation as in currently available processes like SLA or FDNI, a sophisticated process planning system is developed. In the process planner, CAD models(STEP AP203) are partitioned into 3D manufacturable volumes called 'Ueposition feature segment"(DFS) after machining features called "machining feature segmenf'(MFS) are extracted from the initial CAD model. Once MFS and DFS are identified, the process planner arranges them into a chain of processes and automatically generates machining information for each DFS and MFS. The goal of this paper is to present a framework for a process planning system for hybrid RP processes and to outline the geometric algorithms involved in developing such an environment.