• 제목/요약/키워드: AM materials

검색결과 474건 처리시간 0.027초

유산균에 의해 변화된 황기-포스트바이오틱스 다당류가 대식세포에 미치는 영향 (Effect of Astragalus membranaceus-postbiotics Polysaccharide Changed by Lactic Acid Bacteria on Macrophage)

  • 김연숙;신현영;정원비;하은지;구자평;신지영;유광원
    • 한국식품영양학회지
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    • 제37권1호
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    • pp.17-29
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    • 2024
  • To increase industrial applicability of Astragalus membranaceus (AM) as immunostimulating materials, hot-water extract (AME) was prepared from AM and fermented with Kimchi-lactic acid bacteria (Lactobacillus sakei & Leuconostoc mesenteroides) to prepare fermented AM-postbiotics (FAME). Although FAME prepared from AM-postbiotics did not show a significant enhancement in macrophage stimulating activity compared to non-fermented AME, crude polysaccharide (FAME-CP) fractionated by EtOH precipitation from FAME showed significantly higher macrophage stimulating activity than AME-CP. Compared to AME-CP, FAME-CP showed dramatic changes in component sugar and molecular weight distribution. FAME-CP was a polysaccharide with a major molecular weight distribution of 113.4 kDa containing Man (44.2%), Glc (19.3%), Gal (10.2%), GalA (10.2%), and Ara (7.4%) as sugar components. FAME-CP with enhanced macrophage stimulatory activity not only increased expression levels of mRNA genes encoding macrophage-activated factors (iNOS, TNF-α, MCP-1, IL-6, and COX-2), but also led the nuclear translocation of activated p65 and c-Jun. In conclusion, crude polysaccharide from AM-postbiotics fermented with lactic acid bacteria could increase industrial applicability as a functional material with enhanced immunostimulating activity than AME-CP.

MC 시뮬레이션을 이용한 Aft-Multiple-Silt 시스템의 산란선 제거 효과 평가 (Evaluation of Scatter Reduction Effect of the Aft-Multiple-Slit (AMS) System Using MC Simulation)

  • 장지나;서태석;장도윤;장홍석;김시용
    • Radiation Oncology Journal
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    • 제28권4호
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    • pp.224-230
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    • 2010
  • 목적: 본 연구에서는 콘빔 CT에서 산란선 제거를 위한 aft-multple-slit (AMS) 시스템을 설계하였다. 예비 연구로서 본 시스템의 효용성을 검증하기 위해 MC 시뮬레이션을 수행하였다. 대상 및 방법: 가상 시뮬레이션은 산란선과 산란선+일차선을 계산할 수 있는 MCNPX의 radiography tally 5를 이용하였다. AMS는 빔의 발산성을 고려한 각이 동일한 아크 형태이고, 길이 방향에서의 산란선을 막는다. AMS의 효용성을 위한 평가는 AMS를 사용하지 않았을 때의 일차선과 산란선을 비교함으로써 수행되었다. 2D projection 영상을 얻기 위해 전체의 AMS는 한번의 캔트리 회전 후 AMS에 의해 가려진 부분의 영상 획득을 위해 다시 한 번 회전하는 구조이다. 결과: 일차선의 2D projection 영상은 모든 AMS의 폭에서 그리고 AMS를 사용하지 않았을 때에도 동일하였으나 일차선+산란선의 2D projection 영상은 slit의 폭에 따라 결과가 변했다. Slit의 폭을 5 mm, 10 mm, 15 mm, 20 mm로 하였을 때 평균 산란성 제거율은 29%, 15%, 9%, 8%였다. 결론: 본 연구에서는 AMS를 이용한 콘빔 CT의 산란선 제거 효과를 평가하였다. MC 시뮬레이션을 이용한 본 시스템의 사전 연구에서는 상당한 산란선 제거 효과를 보여주었다.

털두꺼비하늘소에 대한 식물정유와 농자재의 훈증독성 (Fumigant Toxicity of Essentail Oils and Agricultural Materials against Moechotypa diphysis Pascoe (Coleoptera: Cerambycidae))

  • 안희근;노두진;양정오;윤창만;김길하
    • 농약과학회지
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    • 제12권3호
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    • pp.302-306
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    • 2008
  • 본 연구는 표고 원목을 재배시에 골목을 가해하는 털두꺼비하늘소(Moechotypa diphysis) 성충에 대하여 농자재 4종(chungkiller, jinap, purunjunsa, ungsalta)과 식물정유 3종(rosemary, sage, pennyroyal)에 대해서 접촉독성, 훈증독성 및 식물정유와 혼합시 상승효과를 검토하였다. 접촉독성은 농자재 4종 모두 100% 살충율을 보였으나, 3종의 식물정유는 모두 0% 살충율을 나타내었다. 이 4가지 농자재를 이용하여 $3{\sim}24$시간까지 훈증독성 발현속도는 1 mL/1 L air의 농도에서 jinap과 chungkille는 3시간 이내, ungsalta와 puruniunsa는 6시간 이내에 100% 살충효과를 보였다. 15 L(air)의 비닐용기에서는 10 mL의 처리농도에서 ungsalta(0%)를 제외한 3종 약제 모두 100%의 훈증효과를 나타내었다. 5 mL의 처리농도에서는 jinap과 prunjunsa 만이 50%와 62.6%를 나타내었으나 대조약제인 metam-sodium은 100%의 훈증효과를 나타내었다. Jinap과 Pennyroyal oil의 5:1(mL/15 L)혼합 처리에서 100%의 훈증효과를 나타내었으며, 단제 처리보다 높았다.

김명관고택의 미기후 특성과 외진노출기둥의 함수율 양상에 관한 연구 (A Study on the Characteristic Micro-Climate of Myeong-Kwan Kim House and the Moisture Content Behavior of Outside Exposed Columns)

  • 박용신;김윤상
    • 한국농촌건축학회논문집
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    • 제22권3호
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    • pp.33-40
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    • 2020
  • Wood is one of the main materials of wooden building. Hanok also uses wood as its main component. Recently, Hanok continues to be built. Wood is affected by the climatic environment. The growth of decay bacteria is activated at more than 80% relative humidity. The microclimate environment and moisture content were measured for architectural cultural properties that have been maintained for a long time as a wooden building. The method analyzed the measured data by distinguishing between cloudy and sunny days. In the case of the old house, Anchae moisture content was higher than that of Sarangchae. This seems to be due to the narrow front yard or the planting of trees. The microclimate environment inside the house began to decrease in humidity from 8 am. According to the survey data, the relative humidity was less than 80% from 9 am when there was wind around 4-6 am. It appeared an hour earlier than in the absence of wind. As a result, the time interval for dehumidifying of wood was widened. Therefore, the wooden building is open to the front so there is airflow under the eaves during the daytime and wind in the morning appear to be alternatives in order to lower the moisture content.

AM50 마그네슘 합금의 다이캐스팅 공정에 관한 연구 (A Study on the Die-casting Process of AM50 Magnesium Alloy)

  • 장창우;김순국;한수훈;서용권;강충길;이준희;박준홍
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2005년도 춘계학술대회 논문집
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    • pp.415-418
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    • 2005
  • In recent years, Magnesium (Mg) and its alloys have become a center of special interest in the automotive industry. Due to their high specific mechanical properties, they offer a significant weight saving potential in modem vehicle constructions. Most Mg alloys show very good machinability and processability, and even the most complicated die casting parts can be easily produced. The die casting process is a fast production method capable of a high degree of automation for which certain Mg alloys are ideally suited. Although Mg alloys are fulfilling the demands for low specific weight materials with excellent machining and casting abilities, they are still not used in die casting process to the same extent as the competing material aluminium. One of the reasons is that effects of various forming variables for die casting process is not closely examined from the viewpoint of die design. In this study, step die and flowability tests for AM60 were performed by die casting process according to various combination of casting pressure and plunger velocity. Microstructure and Victors hardness tests were examined and performed for each specimen to verify effects of forming conditions.

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Synthesis of Amorphous Matrix Nano-composite in Al-Cu-Mg Alloy

  • Kim, Kang Cheol;Park, Sung Hyun;Na, Min Young;Kim, Won Tae;Kim, Do Hyang
    • Applied Microscopy
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    • 제44권3호
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    • pp.105-109
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    • 2014
  • The microstructure of as-quenched $Al_{70}Cu_{18}Mg_{12}$ alloy has been investigated in detail using transmission electron microscopy. Al nano-crystals about 5 nm with a high density are distributed in the amorphous matrix, indicating amorphous matrix nano-composite can be synthesized in Al-Cu-Mg alloy. The high density of Al nano-crystals indicates very high nucleation rate and sluggish growth rate during crystallization possibly due to limited diffusion rate of solute atoms of Cu and Mg during solute partitioning. The result of hardness measurement shows that the mechanical properties can be improved by designing a nano-composite structure where nanometer scale crystals are embedded in the amorphous matrix.

Silicene on Other Two-dimensional Materials: Formation of Heterostructure

  • Kim, Jung Hwa;Lee, Zonghoon
    • Applied Microscopy
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    • 제44권4호
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    • pp.123-132
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    • 2014
  • Silicene is one of the most interesting two-dimensional materials, because of not only the extraordinary properties similar to graphene, but also easy compatibility with existing silicon-based devices. However, non-existing graphitic-like structure on silicon and unstable free-standing silicene structure leads to difficulty in commercialization of this material. Therefore, substrates are essential for silicene, which affects various properties of silicene and supporting unstable structure. For maintaining outstanding properties of silicene, van der Waals bonding between silicene and substrate is essential because strong interaction, such as silicene with metal, breaks the band structure of silicene. Therefore, we review the stability of silicene on other two-dimensional materials for van der Waals bonding. In addition, the properties of silicene are reviewed for silicene-based heterostructure.

레이저로 적층 제조한 금속 기지재 복합재료의 설계 및 제조 연구동향 (Selective Laser Melting of Metal Matrix Composites: A Review of Materials and Process Design)

  • 김민겸;김태환;김주원;김동원;방영젠;노종환;서종환
    • Composites Research
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    • 제34권4호
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    • pp.212-225
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    • 2021
  • 금속 기지재 복합재료들(MMCs, Metal matrix composites)은 우수한 기계적 물성(강성, 강도, 마모 저항성, 경도 등)과 뛰어난 특성(열전도, 전기전도도, 부식 저항 등)으로 다양한 산업군에 활용되고 있다. 적층제조 기술이 발달함에 따라 복잡한 형상을 시간과 비용을 절약하여 제조할 수 있다는 이점으로, 적층 제조한 MMCs에 관한 연구가 활발하게 이루어지고 있다. 하지만 MMCs를 적층 제조할 경우, 다양한 원인들에 의해 여러 문제들이 발생할 수 있다. 따라서 본 연구에서는 다양한 MMCs의 특징들을 소개하고, 위의 문제들이 발생하는 원인을 고찰하여 소재와 Powder bed fusion (PBF) 공정 설계 관점에서 해결책을 제시하고자 한다. 본 논문은 향후 PBF 방식으로 적층 제조한 MMCs를 개발할 때 설계 및 제조 가이드라인을 제시하여 줄 수 있을 것이다.

감마선을 이용한 복합재료의 섬유체적분율 측정 (Fiber Volume Fraction Measurement of Fiber Reinforced Plastics by Using Gamma-Ray)

  • 장지훈;조경식;장홍근;박지홍;이종오
    • 비파괴검사학회지
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    • 제17권3호
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    • pp.151-155
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    • 1997
  • 본 연구에서는 방사성동위원소 $^{241}Am$의 감마선 감쇠를 이용하여 유리섬유 및 탄소섬유 복합적층판의 섬유체적분율을 비파괴적으로 측정하였다. NaI(Tl) detector에 의해 섬유와 기지의 방사선 감쇠계수를 측정하고, 시험체의 두께를 $2{\sim}20mm$로 변화시키면서 섬유체적분율을 측정하였으며, 적층판과 에폭시판을 겹쳐서 섬유체적분율을 변화시키면서 섬유체적분율을 측정하였다. 연구 결과 단면을 현미경으로 관찰하여 구해진 값과 비교 할 때 오차 ${\pm}1{\sim}2.5%$ 범위 이내로 측정이 가능하였으며, 방사선원의 energy, activity의 선택에 따라서 대부분의 복합재료에 적용이 가능할 것으로 판단된다.

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Fused Deposition Modeling of Iron-alloy using Carrier Composition

  • Harshada R. Chothe;Jin Hwan Lim;Jung Gi Kim;Taekyung Lee;Taehyun Nam;Jeong Seok Oh
    • Elastomers and Composites
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    • 제58권1호
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    • pp.44-56
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    • 2023
  • Additive manufacturing (AM) or three-dimensional (3D) printing of metals has been drawing significant attention due to its reliability, usefulness, and low cost with rapid prototyping. Among the various AM technologies, fused deposition modeling (FDM) or fused filament fabrication is receiving much interest because of its simple manufacturing processing, low material waste, and cost-effective equipment. FDM technology uses metal-filled polymer filaments for 3D printing, followed by debinding and sintering to fabricate complex metal parts. An efficient binder is essential for producing polymer filaments and the thermal post-processing of printed objects. This study involved an in-depth investigation of and a fabrication route for a novel multi-component binder system with steel alloy powder (45 vol.%) ranging from filament fabrication and 3D printing to debinding and sintering. The binder system consisted of polyvinyl pyrrolidone (PVP) as a binder and thermoplastic polyurethane (TPU) and polylactic acid (PLA) as a carrier. The PVP binder held the metal components tightly by maintaining their stoichiometry, and the TPU and PLA in the ratio of 9:1 provided flexibility, stiffness, and strength to the filament for 3D printing. The efficacy of the binder system was examined by fabricating 3D-printed cubic structures. The results revealed that the thermal debinding and sintering processes effectively removed the binder/carrier from the cubic structures, resulting in isotropic shrinkage of approximately 15.8% in all directions. The scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) patterns displayed the microstructure behavior, phase transition, and elemental composition of the 3D cubic structure.