• Structural Engineering and Mechanics
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• v.82 no.4
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• pp.517-542
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• 2022

The effect of mean angle of wind attack on the flutter critical wind speed of two generic bridge deck cross-sections, viz, one closed box type streamlined section (deck-1) and closed box trapezoidal bluff type section with extended flanges/overhangs (deck-2) type of section have been studied using Computational Fluid Dynamics (CFD) based forced vibration simulation method. Owing to the importance of the effect of the amplitude of forcing oscillation on the flutter onset, its effect on the flutter derivatives and flutter onset have been studied, especially at non-zero mean angles of wind attack. The flutter derivatives obtained have been used to evaluate flutter critical wind speeds and flutter index of the deck sections at non-zero mean angles of wind attack studied and the same have been validated with those based on experimental results reported in literature. The value of amplitude of forcing oscillation in torsional degree of freedom for CFD based simulations is suggested to be in the range of 0.5° to 2°, especially for bluff bridge deck sections. Early onset of flutter from numerical simulations, thereby conservative estimate of occurrence of instability has been observed from numerical simulations in case of bluff bridge deck section. The study aids in gaining confidence and the extent of applicability of CFD during early stages of bridge design, especially towards carrying out studies on mean incident wind effects.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2022.10a
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• pp.386-388
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• 2022

Recently, realistic contents using virtual reality and augmented reality are attracting attention as learning aids. 3D-based contents have the advantage of being able to observe and experience objects from various angles than 2D-based contents shown on a flat surface. In this paper, we propose a content design based on 3D model for Arduino learning in a virtual environment. The Arduino board and sensor were implemented using Blender, and a 3D-based simulator environment was constructed using the Unity engine. The proposed content uses the Arduino board and sensor implemented in 3D so that learners can easily experience the working principle of Arduino and the coding process.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2023.11a
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• pp.192-193
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• 2023

The International Association of Navigational Aids to Navigation (IALA) utilizes the S-200 standard model and test data for product specification development and validation related to generating datasets compliant with the S-201 data format. Currently, they are focusing on improving the S-200 testbed DB performance and extending the IALA Questionnaire survey functionality. In this study, we investigate the design and implementation of features required to manage additional questionnaires in the S-200 testbed.

• International Journal of Computer Science & Network Security
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• v.24 no.4
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• pp.179-191
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• 2024

With the advancement of modern technology, cyber-attacks are always rising. Specialized defense systems are needed to protect organizations against these threats. Malicious behavior in the network is discovered using security tools like intrusion detection systems (IDS), firewall, antimalware systems, security information and event management (SIEM). It aids in defending businesses from attacks. Delivering advance threat feeds for precise attack detection in intrusion detection systems is the role of cyber-threat intelligence (CTI) in the study is being presented. In this proposed work CTI feeds are utilized in the detection of assaults accurately in intrusion detection system. The ultimate objective is to identify the attacker behind the attack. Several data sets had been analyzed for attack detection. With the proposed study the ability to identify network attacks has improved by using machine learning algorithms. The proposed model provides 98% accuracy, 97% precision, and 96% recall respectively.

• Information Systems Review
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• v.25 no.4
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• pp.27-45
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• 2023

The importance of information security has grown alongside the development of information and communication technology. However, companies struggle to select suitable countermeasures within their limited budgets. Sönmez and Kılıç (2021) proposed a model using AHP and mixed integer programming to determine the optimal investment combination for mitigating information security breaches. However, their model had limitations: 1) a lack of objective measurement for countermeasure efficacy against security threats, 2) unrealistic scenarios where risk reduction surpassed pre-investment levels, and 3) cost duplication when using a single countermeasure for multiple threats. This paper enhances the model by objectively quantifying countermeasure efficacy using the beta probability distribution. It also resolves unrealistic scenarios and the issue of duplicating investments for a single countermeasure. An empirical analysis was conducted on domestic SMEs to determine investment budgets and risk levels. The improved model outperformed Sönmez and Kılıç's (2021) optimization model. By employing the proposed effectiveness measurement approach, difficulty to evaluate countermeasures can be quantified. Utilizing the improved optimization model allows for deriving an optimal investment portfolio for each countermeasure within a fixed budget, considering information security costs, quantities, and effectiveness. This aids in securing the information security budget and effectively addressing information security threats.

• Korean Journal of Veterinary Research
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• v.40 no.3
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• pp.471-478
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• 2000

The pharmacokinetic properties of KR-V compounds, recently developed as new anti-HIV agents, were studied after i.v. and p.o. administration in rats. The concentrations of the KR-V series were determined in rat plasma using an high-performance liquid chromatography (HPLC)-UV detection system. Of the 19 KR-V compounds investigated in the present study, only KR-V 3, 10, 14, 16 and 18-1 showed oral bioavailability. The plasma concentration-time data could be adequately described by an one-compartment open model. In the i.v. kinetic study (10mg/kg), the CLt of KR-V 3, 10, 14 and 16 (>4L/hr/kg) were significantly higher than that of KR-V 18-1 (1.1 L/hr/kg). The AUC of KR-V 18-1 was greater ($8.97{\mu}g{\cdot}hr/ml$) than that of the other compounds, but the Vd (0.58 L/kg) was lower. In the p.o. kinetic study (50mg/kg), although the t-1/2 of KR-V 18-1 was shorter than that of the other compounds, the AUC ($3.659{\mu}g{\cdot}hr/ml)$ and $C_{max}(1.891{\mu}g/ml$) were markedly higher. In a seperated in vitro experiment, only KR-V 18-1, of the 5 compounds with bioavailibility, exhibits potent activity against HIV-1 mutant strains. Therefore, KR-V 18-1 is expected to become a new potent anti-AIDS drug candidate/lead compound.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.119-128
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• 2017

This study estimated the optimal nursing workforce and financial costs of providing comprehensive nursing services at hospitals under the national health insurance system. Data on registered nurses, nursing aids, medical institutions, and number of patients were obtained from the Health Insurance Review and Assessment Service. The optimal size of the nursing workforce was calculated using the workload model. A bottom-up approach was used to estimate the annual total financial cost of comprehensive nursing services. The number of registered nurses and nursing aids would need to be increased by 81.75% and 83.23%, respectively, in order to fully apply comprehensive nursing care on a national scale. The additional financial costs for comprehensive nursing services at all hospitals was estimated to be as much as 110.39% of the current cost. For the comprehensive nursing service, nurses with a career and newcomers need to be retained at their hospitals, and the validity of the nurse-patient ratio should be continuously checked. The financial shock to the national health insurance system could be minimized by gradually extending the system to all hospitals.

• Journal of the Korean Institute of Intelligent Systems
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• v.21 no.1
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• pp.80-85
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• 2011

This paper presents the design of the power-assisted controller for the in-wheel type smart wheelchair by using torque estimation that is predicted by relationship between input voltage and output wheel angular velocity. Nowadays, interest of the moving assistant aids is increased according to the increase in population of the elderly and the handicapped person. However some of the moving assistant aids have problems. For example, manual wheelchair has difficulty moving at the slope, because users lack the muscular strength of their arm. In electric wheelchair case, users should be weak by being decreased muscles of upper body. To overcome these problems, power-assisted electric wheelchair are proposed. Most of the power-assisted electric wheelchair have the special rims that can measure the user's power. In here, the rims have to be designed to install the sensors to measure user's power. In this paper, we don't design the rim to measure the man power. To predict the man power, we propose a control algorithm of the in-wheeled electric wheelchair by using torque estimation from the wheel. First, we measure the wheel velocity and voltage at the in-wheel electric wheelchair. And then we extract driving will forces by using proposed mathematical model. Also they are applied at the controller as the control input, we verify to be able to control in-wheel type smart wheelchair by using simulation.

• Journal of Agricultural Extension & Community Development
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• v.21 no.2
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• pp.211-254
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• 2014

Malawi's agricultural extension system has been subjected to a number of criticisms in recent times for failing to contribute significantly to agricultural development and for not responding to the needs of the smallholder farmers. Despite this, extension is still seen as key to improving poverty and rural livelihoods.There is a number of challenges facing extension that require a response from the public sector and other stakeholders. A clear and positive response to these challenges will help shape the future of agricultural extension in Malawi for the benefit of all farmers and the attainment of the broad policy objectives of government: democratization, market liberalization, decentralization, HIV/AIDS crisis, shrinking public sector resources, public sector reform, and co-ordination, etc. The mission is to provide pluralistic demand driven extensions services and promote equalisation and co-ordination in service provision in order to achieve food security at household level, there-by reducing poverty. On the other hand the vision is that 'All farmers' demand and access high quality extension services from those best able to provide them'. DAES implements its extension policy through the District Agricultural Extension Services System (DAESS), based on Model Village Approach.

• IMMUNE NETWORK
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• v.5 no.3
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• pp.157-162
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• 2005

Background: 1-8D gene is a member of human 1-8 interferon inducible gene family and was shown to be overexpressed in fresh colon cancer tissues. Three peptides 1-6, 3-5 and 3-7 derived from human 1-8D gene were shown to have immunogenicity against colon cancer. Methods: To study tumor immunotherapy, of three peptides we established an active immunization model using HHD mice. $D^{b-/-}{\times}{\beta}2$ microglobulin $({\beta}2m)$ null mice transgenic for a chimeric HLA-$A2.1/D^{b-}\;{\beta}2m$ single chain (HHD mice) were challenged with B16/HHD/1-8D tumor cells and were immunized with irradiated peptide-loaded RMA- S/HHD/B7.1 transfectants. In therapy model tumor growth was retarded in HHD mice that were injected with 3-5 peptide-loaded RMA-S/HHD/B7.1. In survival test vaccination with 1-8D-derived peptide protects HHD mice from tumor progression after tumor challenge. Results: These studies show that peptide 3-5 derived from 1-8D gene can be the most effective candidate for the vaccine of immunotherapy against colon cancer and highlight 1-8D gene as putative colon carcinoma associated antigens. Conclusion: We demonstrated that RMA-S/HHD/ B7.1 loaded with 1-8D peptides, especially 3-5, immunization generates potent antitumor immunity against tumor cells in HHD mice and designed active immunization as proper immunotherapeutic protocols.