• Title/Summary/Keyword: AI in Diagnosis

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Detecting colorectal lesions with image-enhanced endoscopy: an updated review from clinical trials

  • Mizuki Nagai;Sho Suzuki;Yohei Minato;Fumiaki Ishibashi;Kentaro Mochida;Ken Ohata;Tetsuo Morishita
    • Clinical Endoscopy
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    • v.56 no.5
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    • pp.553-562
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    • 2023
  • Colonoscopy plays an important role in reducing the incidence and mortality of colorectal cancer by detecting adenomas and other precancerous lesions. Image-enhanced endoscopy (IEE) increases lesion visibility by enhancing the microstructure, blood vessels, and mucosal surface color, resulting in the detection of colorectal lesions. In recent years, various IEE techniques have been used in clinical practice, each with its unique characteristics. Numerous studies have reported the effectiveness of IEE in the detection of colorectal lesions. IEEs can be divided into two broad categories according to the nature of the image: images constructed using narrow-band wavelength light, such as narrow-band imaging and blue laser imaging/blue light imaging, or color images based on white light, such as linked color imaging, texture and color enhancement imaging, and i-scan. Conversely, artificial intelligence (AI) systems, such as computer-aided diagnosis systems, have recently been developed to assist endoscopists in detecting colorectal lesions during colonoscopy. To gain a better understanding of the features of each IEE, this review presents the effectiveness of each type of IEE and their combination with AI for colorectal lesion detection by referencing the latest research data.

Evaluation of Data-based Expansion Joint-gap for Digital Maintenance (디지털 유지관리를 위한 데이터 기반 교량 신축이음 유간 평가 )

  • Jongho Park;Yooseong Shin
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.28 no.2
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    • pp.1-8
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    • 2024
  • The expansion joint is installed to offset the expansion of the superstructure and must ensure sufficient gap during its service life. In detailed guideline of safety inspection and precise safety diagnosis for bridge, damage due to lack or excessive gap is specified, but there are insufficient standards for determining the abnormal behavior of superstructures. In this study, a data-based maintenance was proposed by continuously monitoring the expansion-gap data of the same expansion joint. A total of 2,756 data were collected from 689 expansion joint, taking into account the effects of season. We have developed a method to evaluate changes in the expansion joint-gap that can analyze the thermal movement through four or more data at the same location, and classified the factors that affect the superstructure behavior and analyze the influence of each factor through deep learning and explainable artificial intelligence(AI). Abnormal behavior of the superstructure was classified into narrowing and functional failure through the expansion joint-gap evaluation graph. The influence factor analysis using deep learning and explainable AI is considered to be reliable because the results can be explained by the existing expansion gap calculation formula and bridge design.

Establishment for Improving Productivity of Cattle by Fecal Steroid and Milk Urea Nitrogen analysis - II. Application of Early Pregnancy Diagnosis and Monitoring Postpartum Ovarian Activity

  • Kang, Chung-Boo;Ha, Woo-Song;Kwon, Ji-In;Yu, Young-Sang;Kim, Chul-Ho;Kwak, Soo-Dong
    • Biomedical Science Letters
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    • v.9 no.1
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    • pp.29-36
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    • 2003
  • Progesterone levels in the blood plasma or skim milk of cows are considered to be very useful indicator fur the detection of estrus cycle and early pregnancy diagnosis. During 13 to 14 days after estrus the level of progesterone in plasma or skim milk were not different between the inseminated arid non-inseminated cows. In the pregnant cows the peak level of progesterone reached on 14th day after artificial insemination (AI), but in the absence of conceptus the level declines after the 14th day slowly, and then very rapidly towards the basal level after the 17th day. This low level persists about 4 days, including those of estrus and ovulation a highly characteristic pattern which differs so markedly from that in the pregnant cows. Progesterone levels in blood plasma or skim milk can provided a reliable diagnosis of early pregnancy and monitoring ovarian activity in cows. The mean $\pm$ standard deviation of milk urea nitrogen(MUN) and protein concentration in the cows at 9 herds were 17.7$\pm$2.35 mg/dL and 3.2$\pm$0.17%, respectively. The days of nonpregnant after parturition was shorter in the cows in which the lower level of MUN than higher level of MUN concentration.

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Comparison of radiographic and computed tomographic acetabular index in small-breed dogs: a preliminary study using Maltese and Shih Tzu

  • Kanthavichit, Kanokporn;Klaengkaew, Auraiwan;Thanaboonnipat, Chutimon;Darawiroj, Damri;Soontornvipart, Kumpanart;Choisunirachon, Nan
    • Journal of Veterinary Science
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    • v.22 no.4
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    • pp.58.1-58.13
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    • 2021
  • Background: The morphometry of the acetabulum is one source of information that assists in the clinical diagnosis of the hip and influences the proper selection of a prosthesis, reducing post-operative complications such as those seen in total hip replacement (THR). However, acetabular parameters in small-breed dogs are rarely reported. Objectives: To investigate acetabular parameters using radiography and computed tomography (CT) in small-breed dogs with Maltese and Shih Tzu dogs used as model breeds. Methods: Standard calibrated, extended hip radiographs and CT images were obtained. Subsequently, acetabular width (AW) in various directions was measured using radiography and CT, whereas acetabular depth (AD) was obtained by CT. Acetabular index (AI) is a ratio calculated from AD and AW. Results: The values of AW and AD were much higher in Shih Tzu than in Maltese dogs. Male Shih Tzus showed higher values of these parameters than females, while sex-based differences in most of the parameters could not be detected in Maltese. Body weight, but not age, influenced AWs and ADs. While AWs and ADs were influenced by several factors, AI was comparable among the assessed factors and between Maltese and Shih Tzu dogs (p = 0.172; 31.42 ± 1.35 and 32.60 ± 1.80, respectively). Also, AI did not vary with breed, sex, or body size. Conclusions: The obtained radiographic and CT acetabular parameters could be useful as guidelines for evaluating the acetabulum of small-breed dogs in clinical practice.

Study on Biochemical Pollutant Markers for Diagnosis of Marine Pollution VII. Changes in Lipid Components of Flounder (Paralichthys olivaceus) in the South Sea (해양오염의 진단을 위한 생화학적 오염지표에 관한 연구 VII. 남해산 넙치 (Paralichthys olivaceus)의 지질성분의 변화)

  • CHOI Jin-Ho;KIM Dong-Woo;KIM Jung-Hwa;PARK Chung-Kil;YANG Dong Beom
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.6
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    • pp.882-888
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    • 1998
  • This study was designed as a part of efforts to investigate the biochemical pollutant markers for diagnosis of marine pollutions by changes in lipid components of the flounder (Paralichthys olivaceus) in the South Sea of Korea, Hemoglobin levels in serum of cultured flounders in the South Sea were lower ($4\~17\%$) than those of wild flounder in Pohang as a control group. Triglyceride (TG), Total and low density lipoprotein (LDL)-cholesterol contents in serum of cultured flounders in the South Sea were $12\~25\%,\;9\~19\%$ and $17\~25\%$ respectively which are higher than those of wild flounder in Pohang. Atherogenic index (AI) and T-Chol/PL ratios in serum of cultured flounders in the South Sea were significantly higher($26\~43\%$ and $17\~26\%$ respectively) than those of wild flounder in Pohang. These results suggest that near-coastal water as well as neritic water of the South Sea might be affected by pollutant input as well as the Yellow Sea of Korea.

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Estimation of Motor Deterioration using Pulse Signal and Insulation Resistance Measurement Algorithm (펄스 신호 및 절연저항 측정 알고리즘을 이용한 전동기 열화 추정)

  • Jeong, Sungin
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.22 no.5
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    • pp.111-116
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    • 2022
  • The causes of motor burnout include overload, phase loss, restraint, interlayer short circuit, winding ground fault, instantaneous overvoltage, and the rotor contacting the stator, leading to insulation breakdown, leading to breakdown or electrical accidents. Therefore, equipment failure causes not only loss due to cost required for equipment maintenance/repair, but also huge economic loss due to productivity decrease due to process stop because the process itself including the motor is stopped. The current level of technology for diagnosing motor failures uses vibration, heat, and power analysis methods, but there is a limit to analyzing the problems only after a considerable amount of time has passed according to the failure. Therefore, in this paper, a device and algorithm for measuring insulation resistance using DC AMP signal was applied to an industrial motor to solve this problem. And by following the insulation resistance state value, we propose a diagnosis of deterioration and failure of the motor that cannot be solved by the existing method.

A Clinical Investigation in Primary Male Infertility During Recent 5 Years (최근 5년간 원발성 남성불임증 환자의 임상적 분석)

  • Kim, Tae-Hyoung;Kim, Kyung-Do;Kim, Sae-Chul
    • Clinical and Experimental Reproductive Medicine
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    • v.21 no.3
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    • pp.253-259
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    • 1994
  • A clinical investigation was undertaken on primary male infertility patients of recent 5 years. The results obtained were as follow: 1. Suspective etiologic factors were: 1) testicular failure, 36.1 %; 2) varicocele, 18.7%; 3) endocrine abnormality, 13.5%; 4) obstruction, 13.5%; 5) idiopathic, 10.9%; 6) cryptorchidism, 2.6%; 7) necrospermia, 0.9%. 2. On semen analyses, azoospermia was found in 55.8%, single abnormal parameter in 21.5 %, and multiple/all abnormal parameter in 22.7% of the 163 cases. 3. For the evaluation of the sensitivity and specificity of noninvasive variables in predict in obstruction as the cause of azoospermia in patient who had undergone testicular biopsy, the testicular size and serum follicle-stimulating hormone(FSH) level revealed 100% of sensitivity. 4. Among the 43 patients with a testicular biopsy confirmed diagnosis there was a significant difference in testicular size, ejaculate volume(p<0.0001) and serum FSH(p<0.0001) between patients with testicular failure and those with ductal obstruction. 5. Of 93 treated patients with primary male infertility, 42 were managed by medical treatment including endocrine treament, retrograde ejaculation treatment, infection treatment and observation; 29 were managed by surgical treatment including varicocelectomy, vasovasostomy, vasoepididymostomy and TUR of ejaculatory duct; 20 were managed by sperm preparation treatment including artificial insemination(AI), electroejaculation plus AI and vibration ejaculation plus AI ; 2 were managed by microscopic epididymal sperm aspiration plus IVF, repectively. 6. 42 patients who could be followed-up, 21 patients(50%) impregnated their wives.

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Aberrant Expression of E-cadherin in Lung Tissues of Patients with Probable Lung Cancer

  • Yuan, Yu-Lin;Wang, Yu-Ming;Liu, Hua;Qin, Gui-Fang;Tang, Ai-Guo;Duan, Yong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.10
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    • pp.5149-5153
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    • 2012
  • Introduction: This study assessed the relationship of E-cadherin mRNA and protein expression with the diagnosis of lung cancer with the aim of providing an auxiliary diagnostic method. Methods: Semi-quantitative nested RT-PCR and western blotting were applied to detect E-cadherin mRNA transcripts and protein, respectively, in 30 cases of diagnostic lung cancer, 30 cases of clinically suspected patients with lung cancer and 30 cases of other disease. Immunohistochemical staining was also used to detect E-cadherin. Results: Remarkably decreased levels of relative E-cadherin mRNA value and increased E-cadherin protein negativity were observed in probable lung cancer, when compared with possible lung cancer and others. With a threshold of 1.45, relative E-cadherin mRNA value showed a sensitivity of 90% and a specifity of 83% for the diagnosis of lung cancer. The combination of decreased relative E-cadherin mRNA value and negative E-cadherin protein increased the specificity and sensitivity. Conclusion: These data suggest that Chinese patients with diagnostic lung cancer have similar decreased levels of relative E-cadherin mRNA and E-cadherin protein value in the lung cancer tissues as in lung cancer patients in other countries. Measurement of relative E-cadherin mRNA and protein values in lung cancer tissues has potential for lung cancer diagnosis.

Mobile App for Detecting Canine Skin Diseases Using U-Net Image Segmentation (U-Net 기반 이미지 분할 및 병변 영역 식별을 활용한 반려견 피부질환 검출 모바일 앱)

  • Bo Kyeong Kim;Jae Yeon Byun;Kyung-Ae Cha
    • Journal of Korea Society of Industrial Information Systems
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    • v.29 no.4
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    • pp.25-34
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    • 2024
  • This paper presents the development of a mobile application that detects and identifies canine skin diseases by training a deep learning-based U-Net model to infer the presence and location of skin lesions from images. U-Net, primarily used in medical imaging for image segmentation, is effective in distinguishing specific regions of an image in a polygonal form, making it suitable for identifying lesion areas in dogs. In this study, six major canine skin diseases were defined as classes, and the U-Net model was trained to differentiate among them. The model was then implemented in a mobile app, allowing users to perform lesion analysis and prediction through simple camera shots, with the results provided directly to the user. This enables pet owners to monitor the health of their pets and obtain information that aids in early diagnosis. By providing a quick and accurate diagnostic tool for pet health management through deep learning, this study emphasizes the significance of developing an easily accessible service for home use.

Application of Transcranial Doppler Ultrasonography(TCD) for the Diagnosis of Migraine : Preliminary Results (Transcranial Doppler Ultrasonography를 이용한 편두통의 진단: 예비연구)

  • Lee, Young-Seok;Kim, Byung-Kun
    • Annals of Clinical Neurophysiology
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    • v.1 no.1
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    • pp.31-35
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    • 1999
  • Dignosis of migraine is only based on the medical history, and objective methods to aid the clinical diagnosisare absent. Although transcranial Doppler ultrasonography (TCD) abnormalities in headache-free migraineurs have been reported previously, diagnostic criteria for migraine is still lacking and this may limit the practical application of TCD for migraine. We prospectively studied several abnormal TCD indices in interictal migraineurs and their sensitivity and specificity to define the optimal diagnostic criteria. Young (20 yrs$age=29.0{\pm}6.1yrs$) were compared to 69 controls (M:F=25:44, Mean $age=31.2{\pm}5.5yrs$). Elevated MFV (> 2SD)was observed in 63% of migraineurs while n 12% of control (p<0.01). High AI (>25%) or high HI (>3.0) was present in 17% of migraineurs, while 3% and none in controls (p<0.01). Sensitivity of elevated MFV, high AI, and high HI was 63%, 17%, 17% and specificity was 88%, 97%, 100%, respectively. If all these indices were combined, sensitivity and specificity reached 69% and 86%. These preliminary results suggest pathophysiological implication of vasospasm in interictal migraineurs, and TCD may be practically applicable for migraine. Optimal diagnostic criteria and therapeutic options for patients with abnormal TCD findings remain to bo determined.

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