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Beneficial effects of natural Jeju groundwaters on lipid metabolism in high-fat diet-induced hyperlipidemic rats

  • Wang, Yan-Chao;Lu, Jin-Miao;Jin, Hui-Zi;Ma, Ai-Niu;Zhang, Jin-Yang;Gong, Nian;Xiao, Qi;Zhu, Bin;Lv, Ying-Fang;Yu, Na;Zhang, Wei-Dong;Wang, Yong-Xiang
    • Nutrition Research and Practice
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    • v.8 no.2
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    • pp.165-171
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    • 2014
  • BACKGROUND: Groundwater is believed to possess many beneficial effects due to its natural source of various minerals. In this study, we examined the effects of natural Jeju groundwater S1 (Samdasoo$^{TM}$), S2 and S3 pumped up from different locations of Jeju Island, Korea, along with local tap water, on body weight gain, serum lipids and lipoproteins, and liver histopathology in high-fat diet-induced hyperlipidemic rats. MATERIALS/METHODS: Rats were randomly and equally divided into 6 groups. Different water samples were supplied to the hyperlipidemic rats as their daily drinking water and the widely-used anti-hyperlipidemic drug simvastatin was used as a positive control. Body weight, serum lipids and lipoproteins were measured weekly. Liver weight, liver index and liver histopathology were examined after the execution of the rats. RESULTS: After drinking Jeju groundwaters for two months, S2 but not S3 significantly reduced weight growth and serum triglycerides levels and increased high density lipoprotein-C (HDL-C) without affecting total cholesterol or LDL-C. S1 and particularly S2 significantly reduced the severity of liver hypertrophy and steatosis. All Groundwaters had much higher contents of vanadium (S3>S2>S1>>tap water) whereas S1 and S2 but not S3 markedly blocked autoxidation of ferrous ions. CONCLUSION: Jeju Groundwater S1 and particularly S2 exhibit protective effects against hyperlipidemia and fatty liver and hypothesize that the beneficial effect of Jeju Groundwaters may be contributed from blockade of autoxidation of ferrous ions rather than their high contents of vanadium.

The Effect of Dietary Modified Potato Starch By Chemically Denatured Treatment and Potato Starch on the Weight Loss, Lipid Metabolism and Redox Antioxidant System in High Fat Diet-Induced Obese Rats (화학적 변성 및 생감자 전분이 고지방식이로부터 유도된 비만 흰쥐의 지질대사 및 항산화계에 미치는 영향)

  • Park, Soo-Jin;Choi, Mi-Kyeong;Kim, Jin-Suk;Lim, Hak-Tea;Kang, Myung-Hwa
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.10
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    • pp.1251-1257
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    • 2008
  • For the first 42 days, we made rats obese by feeding them potato starch instead of corn starch and after that we fed them transformed potato starch by 4 groups for 70 days. The 4 groups are GPS group, SPS group, EZ group and H40 groups and each were fed normal potato, small potato, enzyme treated potato, and acid treated potato starches, respectively. We determined body weight and feeding efficiency, lipid profiles in serum, lipid peroxidation in tissues and redox antioxidant system as GSH and GP-x in vivo. As a result, there was no difference in the increment of body weight in the groups of GPS, EZ and H40. Therefore EZ group showed lower body weight increment than other groups. While GPS group and SPS group did not show significant difference in blood glucose, cholesterol level, LDL-cholesterol and TC, and their measured values were lower than those of EZ and H40 groups. No significant difference was found in HDL-cholesterol level except for GPS group. Furthermore, when calculating atherogenic index (AI) by HDL-cholesterol and TC contents, H40 group showed higher measured value than other groups. When measuring the lipid peroxidation in serum, kidney and liver tissues, the serum lipid peroxidation in H40 group was higher than others. In the tissue of liver and kidney, EZ and H40 groups showed significantly lower contents than others. The content of GSH showed different tendency in each tissue, but the measured value of GP-x activity was lower in SPS group.

Non-Volatile Organic Acids, Mineral, Fatty Acids and Fiber Compositions in Dolsan Leaf Mustard (Brassica juncea) (돌산 갓의 비휘발성 유기산, 무기질, 지방산 및 섬유소 조성)

  • 박석규;조영숙;박정로;전순실;문주석
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.22 no.1
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    • pp.53-57
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    • 1993
  • The compositions of non-volatile organic acids, mineral, fiber and fatty acids of leaf mustard were investigated. Non-volatile organic acid contents were higher in leaf than in leaf stalk. Of non-volatile organic acids assayed malic acid was the most abundant in both leaf (79.1 mg%) and leaf stalk (46.4mg%), followed by L-ascorbic, oxalic, citric and succinic acids. Mineral contents were also higher in leaf than in leaf stalk. Both leaf and leaf stalk contained calcium most, followed by magnesium, sodium, iron, zinc and copper. It has also been found that leaf mustard contains more iron than any other Cruciferous vegetables reported. The major fatty acid of total lipid was $\alpha$-linolenir acid (63.2% in leaf, 55.3% in leaf stalk). The ratios of polyun-saturated fatty acids to saturated fatty acids (P/S ratio) were 4.1 in leaf and 2.9 in leaf stalk. The content of pectic substances, in terms of alcohol-insoluble solid, of leaf was 9.4% which was 1.4-fold higher than that of leaf stalk. Of pectic substances, hot soluble pectins (HWSP) were present most and followed by sodium hexametaphosphate soluble (HXSP) and HCI soluble pectins (HSP). Total dietary fiber content of mustard leaf was 2.68% and in general, higher content of total dietary fiber than leaf had. Neutral detergent fiber content was higher than acid detergent fiber, and cellulose was higher than hemicellulose by 2.1-fold in leaf stalk.

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Artificial Intelligence Algorithms, Model-Based Social Data Collection and Content Exploration (소셜데이터 분석 및 인공지능 알고리즘 기반 범죄 수사 기법 연구)

  • An, Dong-Uk;Leem, Choon Seong
    • The Journal of Bigdata
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    • v.4 no.2
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    • pp.23-34
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    • 2019
  • Recently, the crime that utilizes the digital platform is continuously increasing. About 140,000 cases occurred in 2015 and about 150,000 cases occurred in 2016. Therefore, it is considered that there is a limit handling those online crimes by old-fashioned investigation techniques. Investigators' manual online search and cognitive investigation methods those are broadly used today are not enough to proactively cope with rapid changing civil crimes. In addition, the characteristics of the content that is posted to unspecified users of social media makes investigations more difficult. This study suggests the site-based collection and the Open API among the content web collection methods considering the characteristics of the online media where the infringement crimes occur. Since illegal content is published and deleted quickly, and new words and alterations are generated quickly and variously, it is difficult to recognize them quickly by dictionary-based morphological analysis registered manually. In order to solve this problem, we propose a tokenizing method in the existing dictionary-based morphological analysis through WPM (Word Piece Model), which is a data preprocessing method for quick recognizing and responding to illegal contents posting online infringement crimes. In the analysis of data, the optimal precision is verified through the Vote-based ensemble method by utilizing a classification learning model based on supervised learning for the investigation of illegal contents. This study utilizes a sorting algorithm model centering on illegal multilevel business cases to proactively recognize crimes invading the public economy, and presents an empirical study to effectively deal with social data collection and content investigation.

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The Christianity Education for the Fourth Industrial Revolution Era (제4차 산업혁명 시대를 위한 기독교 교육)

  • Bong, Won Young
    • The Journal of the Korea Contents Association
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    • v.20 no.3
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    • pp.645-660
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    • 2020
  • This study attempts to look at the role that modern Christianity should play on an educational level in order to effectively prepare for the future society in the era of the fourth industrial revolution. In the coming era, various areas of human life, including human labor, are expected to be replaced by AI robots. As new alternatives, the ability to empathize effectively and educate creatively to help develop personality qualities are proposed in a rapidly changing world of uncertainty. Modern Christianity, however, has the responsibility to help solve the problems facing this era in the public as a member of the community beyond the boundaries of the church. The purpose of this study is to examine what education the modern Christianity can present to the world as a public discourse and how that should be done. This study suggests the following points on the proper education for which Christianity will participate in the era of the fourth industrial revolution. First, it is necessary to emphasize a sense of belonging through a sense of community. Second, serious considerations and preparations for education that develops creativity are needed. Third, it is necessary to establish an educational direction that encompasses the entire generation. Fourth, practical education through digital utilization should be implemented in the local community. Finally, Christianity in the era of the fourth Industrial Revolution needs to be more integrated. As the Christian community recognizes that the agenda of the community is its task, it will be able to create a co-existing and symbiotic society.

The Effects of Levan on Blood Lipids and the Absorption of Calcium in Rats Fed a Low Calcium Diet (레반의 혈장지질 감소와 칼슘흡수율 증가 효과)

  • No, Jung-Ran;Park, Sun-Young;Kim, Mi-Kyoung;Jo, Han-Young;Lee, In-Young;Ly, Sun-Yung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.1
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    • pp.51-57
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    • 2007
  • Levan, the fructose polymer is an indigestible carbohydrate regularly consumed by humans. Its physiological functions, in terms of hypocholesterolemic effect and calcium metabolism, have not been well documented. The objective of this study was to investigate the effects of levan on blood lipids and the calcium absorption ratio in rats fed a 0.1% low calcium diet. Thirty rats were divided into three groups and fed a 0.1% low calcium diet (control) or low calcium diets containing either 2.5% levan or 5% levan for eight weeks. The blood lipid and biomarkers relevant to Ca metabolism (urinary Ca and hydroxyproline), the femoral weight and the Ca contents were determined. The body weight gains were lower in the 5% levan group than the control group. Plasma concentrations of triacylglycerol and LDL-cholesterol decreased in the 5% levan group, compared to the control group, but the atherogenic indice were not affected. Blood alkaline phosphatase activity, Ca and urinary hydroxyproline excretion levels were not different in the three groups. The net calcium absorption in rats fed a 5% levan diet was greater than rats fed the control diet, while the femoral weights and Ca contents were not significantly different in the three groups. We concluded that a 5% levan diet could both enhance the calcium absorption and improve the lipid profiles in rats fed a low calcium diet.

A Proposal of Smart Speaker Dialogue System Guidelines for the Middle-aged (중년 고령자를 위한 스마트 스피커 대화 체계 가이드라인 제안)

  • Yoon, So-Yeon;Ha, Kwang-Soo
    • The Journal of the Korea Contents Association
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    • v.19 no.9
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    • pp.81-91
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    • 2019
  • Recently, the nation has been suffering from a variety of problems, such as the rapid aging of the population and the weakening of the family's role due to rapid industrialization, such as the problem of supporting the elderly or the decline in the quality of supporting them. Among them, the issue of supporting the sentiment of the elderly is a major issue in terms of the quality of the stimulus. The best solution would be to resolve this issue of emotional support through various physical and human support. However, due to various limitations, access to efficient utilization of resources is being sought, among which support efforts through the convergence of digital technologies need to be noted. In this study, we took note of the problems of aging population shortage due to aging phenomenon and the problems of the emotional side of the problem of declining quality of the service, and analyzed the types of digital technology applied to support the emotional side through the convergence of digital technology. Among them, the Commission proposed emotional support through smart speakers, confirming the possibility of supporting the elderly through smart speakers. In addition, the Commission proposed guidelines for smart speaker communication systems to support the sentiment of older adults by conducting an in-depth interview with the In-Depth interview with the evaluation of the usability of smart speakers for older people. Based on the results of this study, it is expected that it will be the basic data for designing a communication system when developing smart speakers to support the emotions of the elderly.

An Auto-Labeling based Smart Image Annotation System (자동-레이블링 기반 영상 학습데이터 제작 시스템)

  • Lee, Ryong;Jang, Rae-young;Park, Min-woo;Lee, Gunwoo;Choi, Myung-Seok
    • The Journal of the Korea Contents Association
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    • v.21 no.6
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    • pp.701-715
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    • 2021
  • The drastic advance of recent deep learning technologies is heavily dependent on training datasets which are essential to train models by themselves with less human efforts. In comparison with the work to design deep learning models, preparing datasets is a long haul; at the moment, in the domain of vision intelligent, datasets are still being made by handwork requiring a lot of time and efforts, where workers need to directly make labels on each image usually with GUI-based labeling tools. In this paper, we overview the current status of vision datasets focusing on what datasets are being shared and how they are prepared with various labeling tools. Particularly, in order to relieve the repetitive and tiring labeling work, we present an interactive smart image annotating system with which the annotation work can be transformed from the direct human-only manual labeling to a correction-after-checking by means of a support of automatic labeling. In an experiment, we show that automatic labeling can greatly improve the productivity of datasets especially reducing time and efforts to specify regions of objects found in images. Finally, we discuss critical issues that we faced in the experiment to our annotation system and describe future work to raise the productivity of image datasets creation for accelerating AI technology.

Search for the Education of High-Tech Emotional Textile and Fashion (하이테크 감성 섬유패션의 교육 방향에 대한 모색)

  • Youn Hee Kim;Chunjeong Kim;Youngjoo Na
    • Science of Emotion and Sensibility
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    • v.26 no.3
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    • pp.69-82
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    • 2023
  • High-tech sensibility textile and fashion, in which consumers' emotions and various textile and fashion technologies are converged, is an important industrial group. It is important to develop the ability to apply in practice by gathering the creative by understanding other fields and exchanging ideas through interdisciplinary collaboration in the field of emotional engineering. Through interdisciplinary research and collaboration, talent must be nurtured of individuals who would lead the era of the 4th Industrial Revolution with the ability to empathize with others as well as the creative convergence-type intellectual ability necessary for the rapidly changing society. To determine content-creation methods, basic research is conducted. Additionally, this study investigates on the current status and educational process of the emotional textile-fashion industry worldwide. To nurture talents in the textile and fashion sensibility science, the basic contents are created to manage the knowledge that delivers sensibility science and the ICT related to this field, as well as in the intensive, PB-style conceptual design based on sensibility. The process from derivation of consumer emotion analysis and product development can be experienced through smart kit practice. Moreover, various methods are developed to set up intellectual property rights generated while developing ICT convergence products as start-ups. The study also covers new knowledge rights to develop emotional textile fashion.

An Analysis of Nursing education Research in China : 1990-1998 (중국 간호교육관련 연구실태 분석)

  • Ko Il-Sun;Li Chun-Yu;Kim Jing-Ai
    • The Journal of Korean Academic Society of Nursing Education
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    • v.5 no.2
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    • pp.177-190
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    • 1999
  • This study has been conducted on the basis of the literature review of Nursing Education Research in China from 1990 through August 1998. Its purpose was to support the basic data of nursing education which is risen as major revolutionary of nursing in China and those for exchange of information between Korea-China nursing education. It is retrospective and descriptive research analyzing one hundred eighty articles published in The Journal of China Nursing. The results of the study were as follows. 1. Only 33.3% of the professors of Technical Nursing School who have played of major role of nursing education in China have carried out the study related to nursing education. Baccalaureate program professors have marked 22.2% of all studies, and diploma program professors have done 12.2% of all. Therefore, the professors of above the diploma program have done total 44.4%. It explains that the professors of baccalaureate and diploma programs have done more studies related to nursing education than those of Technical Nursing School. 2. In terms of the study design, most of the studies(38.8%) were case studies introducing the curriculum contents that were done at education institutions. And then, 28.5% were reviewing the articles, and 15.6% were descriptive studies. 3. In terms of the content of the study, 38.3% were relevant to education of Technical Nursing School, 15.0% were about baccalaureate education, and 10.4% is about diploma. 4. To analyze the specific contents of the studies ; a. In baccalaureate program, human resources (professor or teaching), course extension, lab, classes, teaching method, education philosophy, goal of education, evaluation method, and human resource development were included. b. In diploma program, teaching contents evaluation method, teaching method, and educational system were included c. In the technical school, there were qualification of professors , teaching method, evaluation method, opening the courses, teaching contents, goal of education and so on. d. Beyond these, there were practice guidance and appraisement, teaching method, and opening new courses which were not specially indicated as educational curriculum and score management as continuing education. What is above tell us that the study regarding development of university system has been progressed actively and widely. It has been for the effort of revolution which based on the China government force to reform of nursing education process during last 10 years. On the base of the result, we suggest the following questions and the alternatives. 1) Since most articles are case studies related to teaching methods and the others doesn't propose the research method. the study which is applied more exact research method is needed. 2) No study is regarding social change and health policy. Because University program, founded in 1983 is on the beginning point, the research about curriculum have to be taken as a top priority as well as to reflect social needs which are based on social changes and national health policy 3) Only one review article study tells nursing Human resource. To appear in large numbers in nursing manpower, avoid the present hospital nurses training system. Then, the study for manpower development which is able to accomplish in many fields has to be advanced. 4) Most studies did not have literature review processes, so it was impossible for researcher to know the past study tendency and there is no relation among studies as to same subject, the education about research method is needed.

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