• Asian Pacific Journal of Cancer Prevention
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• v.16 no.18
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• pp.8145-8147
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• 2016

Background: Atypical squamous cells of undetermined significance (ASCUS) feature a wide variety of cervical cells, including benign and malignant examples. The management of ASCUS is complicated. Guidelines for office gynecology in Japan recommend performing a high-risk human papillomavirus (HPV) test as a rule. The guidelines also recommend repeat cervical cytology after 6 and 12 months, or immediate colposcopy. The purpose of this study was to determine the clinical significance of ASCUS. Materials and Methods: Between January 2012 and December 2014, a total of 162 patients underwent cervical conization for cervical intraepithelial neoplasia grade 3 (CIN3), carcinoma in situ, squamous cell carcinoma, microinvasive squamous cell carcinoma, and adenocarcinoma in situ at our hospital. The results of cervical cytology prior to conization, the pathology after conization, and high-risk HPV testing were obtained from clinical records and analyzed retrospectively. Results: Based on cervical cytology, 31 (19.1%) of 162 patients were primarily diagnosed with ASCUS. Among these, 25 (80.6%) were positive for high-risk HPV, and the test results of the remaining 6 patients (19.4%) were uncertain. In the final pathological diagnosis after conization, 27 (87.1%) and 4 patients (12.9%) were diagnosed with CIN3 and carcinoma in situ, respectively. Conclusions: Although ASCUS is known as a low-risk abnormal cervical cytology, approximately 20% of patients who underwent cervical conization had ASCUS. The relationship between the cervical cytology of ASCUS and the final pathological results for CIN3 or invasive carcinoma should be investigated statistically. In cases of ASCUS, we recommend HPV tests or colposcopic examination rather than cytological follow-up, because of the risk of missing CIN3 or more advanced disease.

• Journal of Internet Computing and Services
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• v.25 no.2
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• pp.113-122
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• 2024

Recently, cutting-edge ICT technologies such as artificial intelligence, blockchain, edge computing, and the Internet of Things have been applied in various fields to create new services and a new digital era. Along with these technological developments, various policies are being implemented in Korea to transform the country from a "Smart City" to a "Platform City". We can create new services and values by linking with the Smart City Integrated Platform and Smart Housing Platform. This paper defines a linkage scenario between a Smart Housing Platform and the Smart 119 Emergency Dispatch Support Service, one of the Smart City Safety Nets. We propose a data transmission protocol and a metadata schema for data exchange between the Smart Housing Platform and the Smart City Integrated Platform to provide the Smart 119 Emergency Dispatch Support Service.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5087-5094
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• 2016

mTOR, the mammalian target of rapamycin, is a conserved serine/threonine kinase which belongs to the phosphatidyl-linositol kinase-related kinase (PIKK) family. It has two complexes called mTORC1 and mTORC2. It is well established that mTOR plays important roles in cell growth, proliferation and differentiation. Over-activation of the mTOR pathway is considered to have a relationship with the development of many types of diseases, including polycystic ovary syndrome (PCOS) and ovarian cancer (OC). mTOR pathway inhibitors, such as rapamycin and its derivatives, can directly or indirectly treat or relieve the symptoms of patients suffering from PCOS or OC. Moreover, mTOR inhibitors in combination with other chemical-molecular agents may have extraordinary efficacy. This paper will discuss links between mTOR signaling and PCOS and OC, and explore the mechanisms of mTOR inhibitors in treating these two diseases, with conclusions regarding the most effective therapeutic approaches.

• Journal of Digital Convergence
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• v.17 no.9
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• pp.193-198
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• 2019

In smart cities around the world, urban environments have become more convenient due to information and communication technology(ICT). However, extant studies reveal that the level of life satisfaction of citizens has not improved compared to that of the pre-smart city and citizens are skeptical about the role of the smart city. This is largely because local culture and needs were neglected during the planing and development of the smart city. The research was conducted on Cambodia as a pilot site and our findings indicate that middle age group's population is significantly small and the society is at risk of losing its culture. Therefore, this paper opens up various ways of embedding cultural programs using technology in order to pass down cultural heritage to young generation, provide an emotional attachment to the inhabitants and further build up a new phase of cultural legacy. This will engender cultural uniqueness to the city and intrigue tourists around the world resulting in the growth of the tourist industry. This research will contribute locally by providing a sense of community to the public and globally by suggesting applicable methodology to other cities that are under the similar context.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.4
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• pp.1123-1146
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• 2023

In South Korea, there have been many studies on efficient building-energy management using renewable energy facilities in single zero-energy houses or buildings. However, such management was limited due to spatial and economic problems. To realize a smart zero-energy city, studying efficient energy integration for the entire city, not just for a single house or building, is necessary. Therefore, this study was conducted in the eco-friendly energy town of Chungbuk Innovation City. Chungbuk successfully realized energy independence by converging new and renewable energy facilities for the first time in South Korea. This study analyzes energy data collected from public buildings in that town every minute for a year. We propose a smart city building-energy management model based on the results that combine various renewable energy sources with grid power. Supervised learning can determine when it is best to sell surplus electricity, or unsupervised learning can be used if there is a particular pattern or rule for energy use. However, it is more appropriate to use reinforcement learning to maximize rewards in an environment with numerous variables that change every moment. Therefore, we propose a power distribution algorithm based on reinforcement learning that considers the sales of Energy Storage System power from surplus renewable energy. Finally, we confirm through economic analysis that a 10% saving is possible from this efficiency.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.5
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• pp.273-283
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• 2022

Banking and finance is a broad term that incorporates a variety of smaller, more specialized subjects such as corporate finance, tax finance, and insurance finance. A virtual assistant that assists users in searching for information about banking and finance terms might be an extremely beneficial tool for users. In this study, we explored the process of searching for information, seeking opportunities, and developing a virtual assistant in the first stages of starting learning and understanding Vietnamese to increase effectiveness and save time, which is also an innovative business practice in Use-case Vietnam. We built the FIBA2020 dataset and proposed a pipeline that used Natural Language Processing (NLP) inclusive of Natural Language Understanding (NLU) algorithms to build chatbot applications. The open-source framework RASA is used to implement the system in our study. We aim to improve our model performance by replacing parts of RASA's default tokenizers with Vietnamese tokenizers and experimenting with various language models. The best accuracy we achieved is 86.48% and 70.04% in the ideal condition and worst condition, respectively. Finally, we put our findings into practice by creating an Android virtual assistant application using the model trained using Whitespace tokenizer and the pre-trained language m-BERT.

• Journal of Nutrition and Health
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• v.37 no.1
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• pp.61-67
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• 2004

This study was conducted to investigate the choline intake of Korean adults for the purpose of preparing a basal data required for the establishment of choline adequate intake (AI). The subjects of 56 Korean young adults were recruited from college students of 20 to 30 years old in Daejeon city. The aliquots of foods that the subjects ate for one day were collected with use of duplicate food collection method and choline content of one day meal directly was analyzed with the use of enzymatic method. Choline intakes of male subjects were in the range of 353.5∼1222.5 mg and those of female subjects were in the range of 213.1 ∼ 722.3 mg. Mean intakes of choline were 658.2 $\pm$ 243.9 mg/day in male subjects and 423.3 $\pm$ 133.6 mg/day in female, therefore choline intake of men was about 200mg higher than that of women. Median value in total subjects was 496 mg, male's median was 608.8 mg, female's median was 419.9 mg. When the subjects were devided into 4 groups by choline intake, as less than 75%, 75∼100%, 100∼125% and over 125% based on choline AI of USA (males: 550 mg, females: 425 mg), there was no significant difference between men (64.3%) and wemen (67.9%) in the distribution of the subjects whose choline intake is under the range of 75∼125% AI of USA. However, 10.7% of men and 21.4% of female had choline intake less than 75% AI of USA while the cases of choline intake higher than 125% AI were 25% in male and 10.7% in female. Thus, it is assumed that female case in choline-deficient state would be two times more than male. When adjusted by body weight, choline intake was 9.5 $\pm$ 3.4 mg/kg in men,8.1 $\pm$ 3.1 mg/kg in women and 8.8 $\pm$ 3,3 mg/kg in total subjects. And choline intake per 1,000 kcal of men, women and total subjects were 277.1 $\pm$ 78.4 mg, 275.9 $\pm$ 62.1 mg and 276.5 $\pm$ 70.1 mg respectively. From these results, it is suggested that these levels of 276.5 $\pm$ 70.1 mg/ 1,000 kcal or 8.8 $\pm$ 3.3 mg/kg B.W. can be used as a reference value for the establishment of AI of choline for Korean, because overall choline intake of these subjects was not in lower state compared to other nutrients intakes obtained from calculation of the food the subjects had taken.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.671-676
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• 2014

Objective: The objective of this study was to establish a program model for use in wide-spread cervical cancer screening. :Methods: Cervical cancer screening was conducted in Zhongshan city in Guangdong province, China through a coordinated network of multiple institutes and hospitals. A total of 43,567 women, 35 to 59 years of age, were screened during regular gynecological examinations using the liquid-based ThinPrep cytology test (TCT). Patients who tested positive were recalled for further treatment. Results: The TCT-positive rate was 3.17%, and 63.4% of these patients returned for follow-up. Pathology results were positive for 30.5% of the recalled women. Women who were younger than 50 years of age, urban dwelling, low-income, had a history of cervical disease, began having sex before 20 years of age, or had sex during menstruation, were at elevated risk for a positive TCT test. The recall rate was lower in women older than 50 years of age, urban dwelling, poorly educated, and who began having sex early. Ahigher recall rate was found in women 35 years of age and younger, urban dwelling, women who first had sex after 24 years of age, and women who had sex during menstruation. The positive pathology rate was higher in urban women 50 years of age and younger and women who tested positive for human papillomavirus. Conclusion: An effective model for large-scale cervical cancer screening was successfully established. These results suggest that improvements are needed in basic education regarding cervical cancer screening for young and poorly educated women. Improved outreach for follow-up is also necessary to effectively control cervical cancer.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.8
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• pp.5009-5022
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• 2014

The purpose of this study was to obtain the serum lipid levels according to the lifestyles, and examine the influence of lifestyles on the serum lipid levels among adults who examined the health checkup in an university hospital. The subjects for this study were 4,112 adults who underwent medical examinations at the health center of a university hospital in Daejeon city from Jan 2012 to Dec 2013. The lifestyles and serum lipid levels of study subjects were obtained from self-recorded questionnaires and medical examination charts of the hospital. As a result, the mean values of the serum lipid levels (TC, HDL-C. LDL-C and TG) and atherogenic index (AI) of the study subjects showed a significantly difference according to the lifestyle, such as age, alcohol consumption, smoking, regular exercise, overeating and meat consumption in both sexes. The TC, HDL-C. LDL-C, TG and AI showed a positive correlation with age, AUDIT score, but the HPI score showed a negative correlation in both sexes. In the age-adjusted odds ratio, the risk ratio of an abnormality of TC, HDL-C. LDL-C, TG and AI increased significantly because there was an increase in the group of everyday overeating and meat consumption, smoking group, no exercise group, and low HPI group than their respective counterparts in both sexes. The above results suggested that the serum lipid levels of the subjects was closely related to increasing age, and lifestyles, such as alcohol consumption, smoking, regular exercise, overeating, and meat consumption.

• Informatization Policy
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• v.26 no.3
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• pp.69-89
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• 2019

In order to implement smart cities that will become living spaces in the fourth industrial revolution era, detailed privacy information such as residents' living information, buildings and facilities information must be collected and processed in real time. While city functions and convenience for individuals are being facilitated, threats to personal information exposure and leakage are also likely to increase at the same time. Therefore, the design concept for personal information protection should be considered and accordingly reflected from the stages of smart city design, technology development and operation planning of intelligent information (AI) facilities. The results of the analysis show that for activation of smart cities and operation of data-driven cities, the concept of Privacy by Design (PbD) has already been introduced in the institutional, industrial and technological aspects, particularly in the cases of European countries and the US. In order to strengthen the local and global competitiveness of smart cities and the country, Korea also needs to actively deploy PbD as a strategy to secure a data-driven economy, which is the core strategy for smart cities. Therefore, the study suggests policy implications focused on approaches to legislative improvement and technology development support, which reflect the basic properties of PbD as defined in the study.