Dietary Choline Intake of Korean Young Adults

한국 젊은 성인 남녀의 콜린 섭취상태

  • 정영진 (충남대학교 생활과학대학 식품영양학과) ;
  • 조효정 (충남대학교 생활과학대학 식품영양학과) ;
  • 나진석 (충남대학교 생활과학대학 식품영양학과)
  • Published : 2004.01.01

Abstract

This study was conducted to investigate the choline intake of Korean adults for the purpose of preparing a basal data required for the establishment of choline adequate intake (AI). The subjects of 56 Korean young adults were recruited from college students of 20 to 30 years old in Daejeon city. The aliquots of foods that the subjects ate for one day were collected with use of duplicate food collection method and choline content of one day meal directly was analyzed with the use of enzymatic method. Choline intakes of male subjects were in the range of 353.5∼1222.5 mg and those of female subjects were in the range of 213.1 ∼ 722.3 mg. Mean intakes of choline were 658.2 $\pm$ 243.9 mg/day in male subjects and 423.3 $\pm$ 133.6 mg/day in female, therefore choline intake of men was about 200mg higher than that of women. Median value in total subjects was 496 mg, male's median was 608.8 mg, female's median was 419.9 mg. When the subjects were devided into 4 groups by choline intake, as less than 75%, 75∼100%, 100∼125% and over 125% based on choline AI of USA (males: 550 mg, females: 425 mg), there was no significant difference between men (64.3%) and wemen (67.9%) in the distribution of the subjects whose choline intake is under the range of 75∼125% AI of USA. However, 10.7% of men and 21.4% of female had choline intake less than 75% AI of USA while the cases of choline intake higher than 125% AI were 25% in male and 10.7% in female. Thus, it is assumed that female case in choline-deficient state would be two times more than male. When adjusted by body weight, choline intake was 9.5 $\pm$ 3.4 mg/kg in men,8.1 $\pm$ 3.1 mg/kg in women and 8.8 $\pm$ 3,3 mg/kg in total subjects. And choline intake per 1,000 kcal of men, women and total subjects were 277.1 $\pm$ 78.4 mg, 275.9 $\pm$ 62.1 mg and 276.5 $\pm$ 70.1 mg respectively. From these results, it is suggested that these levels of 276.5 $\pm$ 70.1 mg/ 1,000 kcal or 8.8 $\pm$ 3.3 mg/kg B.W. can be used as a reference value for the establishment of AI of choline for Korean, because overall choline intake of these subjects was not in lower state compared to other nutrients intakes obtained from calculation of the food the subjects had taken.

Keywords

References

  1. Annu Rev Nutr v.14 Choline and Human nutrition Zeisel,S.H.;Blusztajn,J.K. https://doi.org/10.1146/annurev.nu.14.070194.001413
  2. J Physiol v.75 The effects of components of lecithin upon deposition of fat in the liver Best,C.H.;Huntsman,M.E. https://doi.org/10.1113/jphysiol.1932.sp002899
  3. Lancet v.2 Choline deficiency associated with tatal parenteral nutrition Burt,M.E.;Hanin,I.;Brennan,M.F.
  4. J Am Coll Nutr v.9 Abnormal liver function in malnourished patients receiving total parental nutrition: A prospective randomized study Tayek,J.A.;Bistrian,B.;Sheard,N.F.;Zeisel,S.H.;Blackburn,G.L. https://doi.org/10.1080/07315724.1990.10720353
  5. FASEB J v.5 Choline, an essential nutrient for humans Zeisel,S.H.;da Costa KA;Franklin,P.D.;Alexander,E.A.;LaMont,J.T.;Sheard,N.F.;Beiser,A. https://doi.org/10.1096/fasebj.5.7.2010061
  6. Biochem J v.259 Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver Zeisel,S.H.;Zola,T.;da Costa KA;Pomfret,E.A. https://doi.org/10.1042/bj2590725
  7. Modern nutrition in health and disease(9th ed.) Cholin and Phosphatidylcholine Zeisel,S.H.;Shils,M.E.(ed.);Olson,J.A.(ed.);Shike,M.(ed.);Ross,A.C.(ed.)
  8. Pediatric Nutrition: Theory and Practice Diet and brain function: Available information and misinformation Zeisel,S.H.;Grand,R.J.(ed.);Sutphen,J.L.(ed.);Dietz,W.H.(ed.)
  9. Nutrition and the Brain Biological consequences of choline deficiency Zeisel,S.H.;Wurtman,R.(ed.);Wurtman,J.(ed.)
  10. Dietary Reference Intakes for thiamin, riboflavin, niacin, vitamin $B_6$, folate, $B_{12}$, pantothenic acid, biotin and choline The National Academy of Sciences, Nutrition Research Council(NRC)
  11. Korean. J Animal Sci v.29 no.4 Studies on the interrelationships of Methionine, choline and inorganic sulfate in broiler chicks Ko,Y.G.;Ha,J.K.;Han,I.K.
  12. Korean Biochem J v.25 no.4 Effect of choline deficiency and different fats on the hepatic glutathione-dependent enzyme activities in 2-acetylaminofluorene trend rats Cho,E.Y.;Choi,H.M.;Kim,H.A.;Byun,K.W.;Song,J.H.;Kim,J.H.
  13. Korean J Nutr v.32 no.8 Evidence of memory improvement by phophatidy lcholine supplement at fetus and neonate-Studies of basal fore-brain cholinergic neuronal activities Cheon,Y.H.;Chang,Y.K.;Baik,T.K.
  14. Nutritional assessment(1st revision) Chang,Y.K.;Chung,Y.J.;Moon,H.K.;Yoon,J.S.;Park,H.R.
  15. Japan Food Hygiene J v.34 no.1 Determination of choline on milk and dairy products by enzymatic method Maeda,T.;Okano,C.;Miyake,A.;Sawa,J. https://doi.org/10.3358/shokueishi.34.32
  16. J Nutr Biochem v.1 Choline determination using gas chromatograph-mass spectrometry Zeisel,S.H.;da Costa KA https://doi.org/10.1016/0955-2863(90)90101-P
  17. J Nutr v.125 no.30 Pregnacy and lactation are associatied with diminished concentration of choline and its metabolites in rat liver Zeisel,S.H.;Mar,M.H.;Zhou,Z.W.;da Costa KA
  18. Japan Food Hygiene J v.37 no.2 Determination of choline in spices and beans by HPLC with an electrochemical detector Matsuzawa,M.;Kawai,H.
  19. J AOAC Int v.83 no.1 Determination of choline in milk and infant formulas by enzymatic analysis: collaborative study Woollard,D.C.;Indyk,H.E.
  20. Recommended Dietary Allowance for Koreans(7th Revision) The Korean Nutrition Society
  21. J Korea Diet Assoc v.5 no.2 S study on the development of method for measuring nutrients intakes at the worksite(Ⅱ) Kim,Y.J.;Cho,Y.W.
  22. Comprehensive GRAS survey. usage levels reported for NAS. appendix A substances (group 1) used in regular foods Nutrition Research Council (NRC)
  23. J Am Oil Chem v.60 The phospholipid content of food Welhrauch,J.L.;Son,Y.S. https://doi.org/10.1007/BF02669968
  24. Federation Proc v.41 Effects of consumption of choline and Iecithin on neurological and cardiovascular systems Wood,J.L.;Allison,R.G.