• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.3
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• pp.371-379
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• 2011

Active phased array antenna structure is used for modern multi-function radars. To search targets in high clutter environment, the radar receiver needs high dynamic range performance. Though active phased array antenna structure lead to increase of SNR, the SFDR is not increased. In this paper, high SFDR receiver of X-band active phased array radar was designed and manufactured. One channel digital receiver is connected to 32 T/R modules and one PCB assembly is composed to 2 channel digital receivers with RF part, ADC part, LO distribution part and digital down conversion part. A commercial FIFO board was used for digital receiver measurement about major performance in digital output signal condition. The measured digital receiver gain and SFDR is 33 dB and more than 81 dBc each.

• Investigative Magnetic Resonance Imaging
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• v.17 no.2
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• pp.73-82
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• 2013

Purpose : To determine the quantitative parameters of breast MRI that predict tumor invasion in biopsy-proven DCIS. Materials and Methods: From January 2009 to March 2010, 42 MRI examinations of 41 patients with biopsy-proven DCIS were included. The quantitative parameters, which include the initial percentage enhancement ($E_1$), peak percentage enhancement ($E_{peak}$), time to peak enhancement (TTP), signal enhancement ratio (SER), arterial enhancement fraction (AEF), apparent diffusion coefficient (ADC) value, long diameter and the volume of the lesion, were calculated as parameters that might predict invasion. Univariate and multivariate analyses were used to identify the parameters associated with invasion. Results: Out of 42 lesions, 23 lesions were confirmed to be invasive ductal carcinoma (IDC) and 19 lesions were confirmed to be pure DCIS. Tumor size (p = 0.003; $6.5{\pm}3.2$ cm vs. $3.6{\pm}2.6$ cm, respectively) and SER (p = 0.036; $1.1{\pm}0.3$ vs. $0.9{\pm}0.3$, respectively) showed statistically significant high in IDC. In contrast, E1, Epeak, TTP, ADC, AEF and volume of the lesion were not statistically significant. Tumor size and SER had statistically significant associations with invasion, with an odds ratio of 1.04 and 22.93, respectively. Conclusion: Of quantitative parameters analyzed, SER and the long diameter of the lesion could be specific parameter for predicting invasion in the biopsy-proven DCIS.

• Journal of the Korean Society of Radiology
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• v.83 no.1
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• pp.112-126
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• 2022

Purpose To determine the value of 3 Tesla (T) MRI texture analysis for predicting tumor margin infiltration in soft tissue sarcomas. Materials and Methods Thirty-one patients who underwent 3T MRI and had a pathologically confirmed diagnosis of soft tissue sarcoma were included in this study. Margin infiltration on pathology was used as the gold standard. Texture analysis of soft tissue sarcomas was performed on axial T1-weighted images (WI) and T2WI, fat-suppressed contrast-enhanced (CE) T1WI, diffusion-weighted images (DWI) with b-value of 800 s/mm², and apparent diffusion coefficient (ADC) was mapped. Quantitative parameters were compared between sarcomas with infiltrative margins and those with circumscribed margins. Results Among the 31 patients with soft tissue sarcomas, 23 showed tumor margin infiltration on pathology. There were significant differences in kurtosis with the spatial scaling factor (SSF) of 0 and 6 on T1WI, kurtosis (SSF, 0) on CE-T1WI, skewness (SSF, 0) on DWI, and skewness (SSF, 2, 4) on ADC between sarcomas with infiltrative margins and those with circumscribed margins (p ≤ 0.046). The area under the receiver operating characteristic curve based on MR texture features for identification of infiltrative tumor margins was 0.951 (p < 0.001). Conclusion MR texture analysis is reliable and accurate for the prediction of infiltrative margins of soft tissue sarcomas.

• Journal of Advanced Navigation Technology
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• v.12 no.2
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• pp.139-145
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• 2008

There has been lots of studies on communication systems using millimeter wave recently in many countries, specially in newly assigned 57GHz ~ 64GHz ISM band. Among those studies, IEEE 802.15.3c standard proposes OFDM (Orthogonal Frequency Division Multiplexing) systems for high data rate transmission support. But OFDM method has the PAPR (peak-to-Average Power Radio) problem The PAPR problem is to decline the performance of the transmission system due to signals distorted severely when passing through nonlinear components such as ADC/DAC and power amplifiers. In order to solve the problem of P APR, this paper suggests SSC (Sine Soft Clipping) and analyzes the PAPR, CCDF, PSD, BER by applying SAW(Surface Acoustic Wave) filter and power amplifiers to IEEE 802.15.3.c OFDM WPAN systems.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.11
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• pp.365-368
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• 1997

We are developing a small gamma camera or imaging malignant breast tumors. The small scintillation camera system consists of NaI(Tl) crystal ($60\;{\times}\;60\;{\times}\;6\;mm^3$) coupled to position sensitive photomultiplier tube (PSPMT), nuclear instrument module (NIM), analog to digital converter (ADC), and personal computer. High quality flood source image and hole mask image were obtained using the gamma camera developed in this study. Breast phantom containing $2{\sim}7\;mm$ diameter spheres was successfully imaged with parallel hole collimator. The obtained image displayed accurate activity distribution over the imaging field of view. Linearity and uniformity correction algorithms are being developed. It is believed that the developed small gamma camera could be useful or detection of malignant breast cancer.

• Magazine of the Korean Society of Agricultural Engineers
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• v.13 no.4
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• pp.2471-2478
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• 1971

Go Cong Water Control Project was conducted on its preliminary survey and design by Agricultural development Corporation for the Korean Government, an Executing Agency, and Directorate of Irrigation and Rural Engineering of the Ministry of Land Reform, Agriculture and Fishery Development for the Vietnamese Government, a cooperation Agency, under Korean and Vietnamese Economic and Technical Cooperation Program. The main purposes of the project are aimed at the improvements of irrigation and drainage, and salt water prevention of the Go Cong area located at northern part of the Mekong Delta. All the works from field survey through design to preparing reports were carried out by ADC alone and recently Korean Government submitted the relevant reports to vietnamese Government through official channel. The contents of the project are summarized as following: 1. The project comprises irrigation, drainage and salt water prevention facilities on the benefited area of about 55,000 hectares, covering Go Cong and Dinh Tuong(My Tho) Provinces and it will be possible to cultivate rice cropping twice a year, irrigating all the area in the dry season; 2. With completion of this project, annual production of rough rice and vegetables are anticipated to increase by 222,600 .T. and 142,600 M.T. respectively and the internal rateof return stants at 26 per cent, applying for the exchange rate of US $ 1 to VN $ 275. 3. Total investments required for the project are estimated at US $ 56,394,000 of which actual construction cost is estimated at US $ 39,183,000. The project has planned to be d to be developed by four stages, taking bout 7 years. 4. The project needs for three places of pumping plants. 57Km of feed and main irrigation canals, 81Km of drainage channels, 97Km of dike, 23 places of sluices and navigation locks, etc.

• Korean Journal of Animal Reproduction
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• v.25 no.4
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• pp.295-304
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• 2001

Characterization of quantitative trait loci (QTL) was investigated in the experimental crosses between Berkshire and Yorkshire breed. A total of 525 F$_2$ progenies from 65 matting of F$_1$ Parents were produced. Phenotypic measurements included average daily gain (ADG), average back fat thickness (ABF), and loin eye area (LEA). To identify the presence of QTL for reproductive performance, birth weight (BWT) and body weight at 16 days (16DAY) were included as indirect trait. QTL segregation was deduced using 8 markers assigned to chromosome 2 (SSC2). Quantitative trait locus analyses were performed using interval mapping by regression under line-cross model. Presence of imprinting was tested under the statistical model that separated the expression of paternally and maternally inherited alleles. To set the evidence of QTL presence, significance thresholds were derived by permutation following statistical tests, respectively. Genome scan revealed significant evidence for three quantitative trait loci (QTL) affecting growth and body compositions, of which two were identified to be QTL with imprinting expression mode near the ICF II gene region. For average back fat thickness (ABF), a paternally expressed QTL was found on chromosome 2 (SSC2). A paternally expressed QTL affecting loin eye area (LEA) was found in the region of SSC2 where evidence of imprinted QTL was found for average back fat thickness (ABF). For average daily gain (ADG), QTL expressed with Mendelian mode was found on chromosome 2 (SS2). Also, QTL affecting average daily gain (ADC), was identified to be expressed with Mendelian express mode.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.44 no.2
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• pp.34-45
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• 2007

Digital decimation filter is inevitable in oversampled sigma-delta A/D converters for the sake of reducing the oversampled rate to Nyquist rate. This paper presented a Verilog-HDL design and implementation of an area-efficient digital decimation filter that provides time-to-market advantage for sigma-delta analog-to-digital converters. The digital decimation filter consists of CIC(cascaded integrator-comb) filter and two cascaded half-band FIR filters. A CSD(canonical signed digit) representation of filter coefficients is used to minimize area and reduce in hardware complexity of multiplication arithmetic. Coefficient multiplications are implemented by using shifters and adders. This three-stage decimation filter is fabricated in $0.25-{\mu}m$ CMOS technology and incorporates $1.36mm^2$ of active area, shows 4.4 mW power consumption at clock rate of 2.8224 MHz. Measured results show that this digital decimation filter is suitable for digital audio decimation filters.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.5
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• pp.1881-1895
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• 2015

Background: The vascular endothelial growth factor family has been implicated in tumorigenesis and metastasis. The prognostic value of each vascular endothelial growth factor family member, particular VEGF/VEGFR co-expression, in patients with non-small lung cancer remains controversial. Materials and Methods: Relevant literature was identified by searching PubMed, EMBASE and Web of Science. Studies evaluating expression of VEGFs and/or VEGFRs by immunohistochemistry or ELISA in lung cancer tissue were eligible for inclusion. Hazard ratios (HRs) and 95% confidence intervals (CIs) from individual study were pooled by using a fixed- or random-effect model, heterogeneity and publication bias analyses were also performed. Results: 74 studies covering 7,631 patients were included in the meta-analysis. Regarding pro-angiogenesis factors, the expression of VEGFA (HR=1.633, 95%CI: 1.490-1.791) and VEGFR1 (HR=1.924, 95%CI: 1.220-3.034) was associated separately with poor survival. Especially, VEGFA over-expression was an independent prognostic factor in adenocarcinoma (ADC) (HR=1.775, 95%CI: 1.384-2.275) and SCC (HR=2.919, 95%CI: 2.060-4.137). Co-expression of VEGFA/VEGFR2 (HR=2.011, 95%CI: 1.405-2.876) was also significantly associated with worse survival. For lymphangiogenesis factors, the expression of VEGFC (HR=1.611, 95%CI: 1.407-1.844) predicted a poor prognosis. Co-expression of VEGFC/VEGFR3 (HR=2.436, 95%CI: 1.468-4.043) emerged as a preferable prognostic marker. Conclusions: The expression of VEGFA (particularly in SCC and early stage NSCLC), VEGFC, VEGFR1 indicates separately an unfavorable prognosis in patients with NSCLC. Co-expression VEGFA/VEGFR2 is comparable with VEGFC/VEGFR3, both featuring sufficient discrimination value as preferable as prognostic biologic markers.

• Journal of Korean Neurosurgical Society
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• v.46 no.5
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• pp.437-442
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• 2009

Objective : To characterize perioperative biomechanical changes after thoracic spine surgery. Methods : Fifty-eight patients underwent spinal instrumented fusions and simple laminectomies on the thoracolumbar spine from April 2003 to October 2008. Patients were allocated to three groups; namely, the laminectomy without fusion group (group I, n = 17), the thoracolumbar fusion group (group II, n = 27), and the thoracic spine fusion group (group III, n = 14). Sagittal (ADS) and coronal (ADC) angles for adjacent segments were measured from two disc spaces above lesions at the upper margins, to two disc spaces below lesions at the lower margins. Sagittal (TLS) and coronal (TLC) angles of the thoracolumbar junction were measured from the lower margin of the 11th thoracic vertebra body to the upper margin of the 2nd lumbar vertebra body on plane radiographs. Adjacent segment disc heights and disc signal changes were determined using simple spinal examinations and by magnetic resonance imaging. Clinical outcome indices were determined using a visual analog scale. Results : The three groups demonstrated statistically significant differences in terms of angle changes by ANOVA (p<0.05). All angles in group I showed significantly smaller angles changes than in groups II and III by Turkey's multiple comparison analysis. Coronal Cobb's angles of the thoracolumbar spine (TLC) were not significantly different in the three groups. Conclusion : Postoperative sagittal balance is expected to change in the adjacent and thoracolumbar areas after thoracic spine fusion. However, its prevalence seems to be higher when the thoracolumbar spine is included in instrumented fusion.