• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.05a
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• pp.393-395
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• 2011

본 논문은 에드 혹 네트워크(Ad hoc network)에서 각 노드는 베터리 기반의 한정된 에너지로 동작 하기 때문에 에너지 효율을 높이기 위한 다양한 라우팅 알고리즘이 연구되고 있다. 에드 혹 네트워크는 많은 수의 노드들이 거리 등의 상호 속성 정보에 의한 노드의 관리 기법에 따라 노드의 에너지를 관리해야 한다. 또한 주어진 망에서 관리 노드 또는 중계 노드 등의 동작 불가능한상태가 되었을 경우 라우팅 경로가 끊어짐으로서 통신이 불가능한 상태가 되는 문제점이 있다. 본 논문에서는 트리망에서 중계 노드로 사용되는 클러스터 헤드 노드가 동작 불가능한 상태가 되었을 경우, 노드의 위치정보를 이용하여 새로운 헤드 노드를 선출하는 ECOPS(Energy conserving Optimal Path Schedule) 알고리즘을 제안 하였다. 특히 제한된 ECOPS 알고리즘을 이용함으로 노드에 대한 라이프타임을 향상 시키고 전체 라우팅 경로가 오랜 시간 동안 지속되는 결과를 보여 주었다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.05a
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• pp.870-873
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• 2013

본 논문에서는 이동 에드 혹 네트워크(Mobile Ad-hoc network: MANET)에서의 상황인식 기반의 스케쥴링 기법인 DDV(Dynamic Direction Vector)-hop 알고리즘을 제안한다. 기존 MANET에서는 노드의 이동성으로 인한 동적 네트워크 토폴리지, 네트워크 확장성 결여의 대한 취약성을 지니고 있다. 또한 노드들의 이동성에 따라 에너지 소모율이 다르며, 에너지 소모율을 최소화하는 라우팅 기법을 선택하는 것이 중요하다. 따라서 본 논문에서는 계층적 클러스터 단위의 동적이 토폴로지에서 노드가 이동하는 방향성 및 시간에 따른 노드의 이동 속성 정보를 고려하여 클러스터를 생성 및 유지하는 DDV-hop알고리즘을 제안한다. 또한 주어진 노드의 위치정보를 이용하여 토폴로지를 형성함에 있어 보다 에너지 효율적인 경로를 탐색하여 최적화된 경로를 제공함에 연구의 목적이 있다. 주어진 모의실험환경에서 노드의 방향성 및 시간에 따른 이동성을 반영함으로써 에너지 효율적인 클러스터링 및 라우팅 경로 알고리즘이 제공되어 네트워크의 최적화된 에너지 소모 결과를 보여주었다.

• International Journal of Computer Science & Network Security
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• v.21 no.3
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• pp.165-171
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• 2021

Vehicular Ad hoc Network (VANET) is an extension paradigm of moving vehicles to communicate with wireless transmission devices within a certain geographical limit without any fixed infrastructure. The vehicles have most important participation in this model is usually positioned quite dimly within the certain radio range. Fuzzy based multi-hop broadcast protocol is better than conventional message dissemination techniques in high-mobility VANETs, is proposed in this research work. Generally, in a transmission range the existing number of nodes is obstacle for rebroadcasting that can be improved by reducing number of intermediate forwarding points. The proposed protocol stresses on transmission of emergency message projection by utilization subset of surrounding nodes with consideration of three metrics: inter-vehicle distance, node density and signal strength. The proposed protocol is fuzzy MHB. The method assessment is accomplished in OMNeT++, SUMO and MATLAB environment to prove the efficiency of it.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.11
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• pp.2699-2707
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• 2013

We proposed the context-awareness routing algorithm DDV (Dynamic Direction Vector)-hop algorithm at Mobile Ad-hoc Network(MANET). MANET has problem about dynamic topology, the lack of scalability of the network by mobile of node. By mobile of node, energy consumption rate is different. So it is important choosing routing algorithms for the minium of energy consumption rate. DDV-hop algorithms considers of the attribute of mobile node, create a cluster and maintain. And it provides a path by searching a route more energy efficient. We apply mobile of node by direction and time, the alogorighm of routning path and energy efficiency clustering is provided, it is shown the result of enery consumption that is optimized for the network.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.20
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• pp.8829-8836
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• 2014

Background: Cyclooxygenase-2 (COX-2), considered to have tumor-promoting potential, is highly expressed in a variety of tumors, including breast cancer. Since the functions and action mechanisms of COX-2 in breast cancer have not been fully elucidated, in the present study, the effects of target inhibiting COX-2 with recombinant adenovirus Ad-COX-2-shRNA on malignant biological behavior were investigated in representative cell lines. Materials and Methods: Breast cancer MDA-MB-231 and MCF-7 cells were transfected with Ad-COX-2-shRNA and COX-2 expression was tested by RT-PCR and Western blotting. Changes in proliferation, apoptosis and invasion of breast cancer cells were detected with various assays including MTT, colony forming, flowcytometry and Transwell invasion tests. The expression of related proteins involved in the cell cycle, apoptosis, invasion and signaling pathways was assessed by Western blotting. Results: COX-2 expression was significantly reduced in both breast cancer cell lines infected with Ad-COX-2-shRNA, with obvious inhibition of proliferation, colony forming rate, G2/M phase passage and invasion, as well as induction of apoptosis, in MDA-MB-231 and MCF-7 cells, respectively. At the same time, proteins related to the cell cycle, anti-apoptosis and invasion were significantly downregulated. In addition, c-myc expression and phosphorylation activation of Wnt/${\beta}$-catenin and p38MAPK pathways were reduced by the Ad-COX-2-shRNA. Conclusions: COX-2 expression is associated with proliferation, apoptosis and invasion of breast cancer cells, and its mechanisms of action involve regulating expression of c-myc through the p38MAPK and Wnt/${\beta}$-catenin pathways.

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.2
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• pp.70-79
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• 2013

Recently, there has been introduced various types of pairing computations to implement ID based cryptosystem for mobile ad hoc network. The Miller algorithm is the most popular algorithm for the typical pairing computation such as Weil, Tate and Ate. In this paper, we analyze the feasibility of concrete data fault injection attack, which was proposed by Whelan and Scott, in terms of regardless of round positions during the execution of the Miller algorithm. As the simulation results, the proposed attack that can be employed to regardless of round positions and coordinate systems is effective and powerful.

• Journal of Korean Academy of Nursing
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• v.33 no.2
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• pp.256-264
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• 2003

Purpose: The purpose of this research was to find out tobacco control education taught graduate, baccalaureate and associate degree-nursing programs in Korea. Method: A valid and reliable questionnaire previously used to assess tobacco use in medical and nursing schools in the United States was translated and revalidated. Surveys were sent out to all the graduate, baccalaureate and associate nursing programs in Korea. All 6-tobacco curricula content areas recommended by the United States National Cancer Institute and the Agency for Health Care Policy and Research was included. Result: Majority of BSN (93.2%-75%) and AD (92.3%-64.1%) programs were teaching health hazards, cancer risk, health effects of tobacco, effects of ETS, contents of cigarette, withdrawal symptoms and high risk groups of smoking as a part of required courses. However, 87.5% (14/16) of graduate, 50.0% (22/44) in baccalaureate, 53.8% (21/39) in associate degree programs were not teaching about the 5 A's. Of those who reported teaching smoking cessation strategies, they were covered most frequently in Community Nursing (50%), Adult Health Nursing (43.8%) on the graduate level, and in Community Nursing (65.9%-BSN, 76.9%-AD) and Adult Health (54.5%-BSN, 74.4%-AD) on the undergraduate level. 31.1% (5/16) in Graduate, 18.2%(8/44) in BSN, 10.3% (4/39) in Associate Degree programs reported that there are no smoking students in their schools and rest of the schools reported either do not know or they have 1 to more than 21% of students smoking. Conclusion: The study results identifies the quantity and level of tobacco control content in three different nursing programs and will help in developing curricular guidelines in the future. Further survey needs to be done on nursing students' knowledge, attitude and belief on smoking and smoking cessation.

• Journal of Integrative Natural Science
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• v.11 no.3
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• pp.139-147
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• 2018

Hippocampal atrophy is a well-established imaging biomarker of Alzheimer disease (AD). However, hippocampus is a non-homogenous structure with cytoarchitecturally and functionally distinct sub-regions or subfield, with each region performing distinct functions. Certain regions of the subfield have shown selective vulnerability to AD. Here, we are interested in studying the effects of normal aging and mild cognitive impairment on these sub-regional volumes. With a reliable automated segmentation technique, we segmented these subregions of the hippocampus in 101 cognitively normal (CN), 135 early mild cognitive impairment (EMCI), 67 late mild cognitive impairment (LMCI) and 48 AD subjects. Thereby, dividing the hippocampus into hippocampal tail (tail), subiculum (SUB), cornu ammonis 1 (CA1), hippocampal fissure (fissure), presubiculum (PSUB), parasubiculum (ParaSUB), molecular layer (ML), granule cells/molecular layer/dentate gyrus (GCMLDG), cornu ammonis 3(CA3), cornu ammonis 4(CA4), fimbria and hippocampal-amygdala transition area (HATA). In this cross sectional study of 351 ADNI subjects, no differences in terms of age, gender, and years of education were observed among the groups. Though, the groups had statistically significant differences (p < 0.05 after the multiple comparison correction) in the Mini-Mental State Examination (MMSE) scores. There was asymmetrical volume loss in the early stages of AD with the left hemisphere showing volume loss in regions that were unaffected in the right hemisphere. Bilateral parasubiculum, right cornu ammonis 1, 3 and 4, right fimbria and right HATA regions did not show any volume loss till the late MCI stages. Our findings suggest that the hippocampal subfield regions are selectively vulnerable to AD and also that these vulnerabilities are asymmetrical especially during the early stages of AD.

• Journal of Music and Human Behavior
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• v.13 no.2
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• pp.49-66
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• 2016

This study investigated the song-induced autobiographical memory of patients with early Alzheimer's Dementia (AD) by comparing the effects of patient-selected songs (M-AD) versus music therapist-selected songs (M-MT). A total of 19 patients with early AD participated in this study. In the M-AD and M-MT conditions, each participant listened to a song and was instructed to recall memory. The time to recall memory, the specificity of the memory, mood changes, and the type of recalled memory were measured. Perceived familiarity and preference of the used songs and association of the song with the recalled memory were also analyzed. The results of the study showed that the M-AD condition elicited more specific memory and positive mood change than the M-MT condition. In addition, AD patients reported a higher level of familiarity with and preference of songs in the M-AD condition, compared to the M-MT condition. These results indicate that patient-selected songs, which have a personal meaning to an individual, could be effectively used for intervening with memory of this population, which would support music therapists to make better decision with regard to song selection. Further studies would be needed to deepen the understanding of autobiographical memory in older population with cognitive impairment and to propose more effective music therapy strategies for intervening with memory.

• 한국노년학
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• v.32 no.3
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• pp.747-758
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• 2012

Detecting probable Alzheimer's disease (AD) at an early stage is crucial in slowing the progression of the disease and initiating drug therapy for more effective symptom management. Therefore, this study aimed to identify linguistic features that allow us to distinguish between patients with AD and normal controls. This paper reports on characteristics of spontaneous speech in subjects in three stages of AD (questionable, mild, moderate) compared with education- and age-matched normal controls. Four components of speech were measured in Korean native speakers with AD and normal aging: speech tempo, hesitation (measured in seconds), rate of articulation errors, and rate of grammatical errors. The results revealed significant differences in most of these speech components among the four groups, including significant differences between normal controls and the questionable AD group in the areas of speech tempo and rate of grammatical errors. Phonological? articulatory ability was preserved in questionable AD, and grammatical ability was preserved in questionable and mild AD. Subjects with moderate AD were severely impaired in grammatical ability. Prospective assessments of spontaneous speech skills using a dialogue and picture-description task are useful in detecting the subtle, spontaneous speech impairments that AD causes even in its early stage.