• Mycobiology
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• v.50 no.2
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• pp.121-131
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• 2022

The rare edible and medicinal fungus Antrodia cinnamomea has a substantial potential for development. In this study, Illumina HiSeq 2000 was used to sequence its transcriptome. The results were assembled de novo, and 66,589 unigenes with an N50 of 4413 bp were obtained. Compared with public databases, 6,061, 3,257, and 2,807 unigenes were annotated to the Non-Redundant, Gene Ontology, and Kyoto Encyclopedia of Genes and Genomes databases, respectively. The genes related to terpene biosynthesis in the mycelia of A. cinnamomea were analyzed, and acetyl CoA synthase (ACS2 and ACS4), hydroxymethylglutaryl CoA reductase (HMGR), farnesyl transferase (FTase), and squalene synthase (SQS) were found to be upregulated in XZJ (twig of C. camphora) and NZJ (twig of C. kanehirae). Moreover, ACS5 and 2,3-oxidized squalene cyclase (OCS) were highly expressed in NZJ, while heme IX farnesyl transferase (IX-FIT) and ACS3 were significantly expressed in XZJ. The differential expression of ACS1, ACS2, HMGR, IX-FIT, SQS, and OCS was confirmed by real-time quantitative reverse transcription PCR. This study provides a new concept for the additional exploration of the molecular regulatory mechanism of terpenoid biosynthesis and data for the biotechnology of terpenoid production.

• Journal of Trauma and Injury
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• v.37 no.2
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• pp.124-131
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• 2024

Purpose: The aim of this study was to utilize the American College of Surgeons Trauma Quality Improvement Program (TQIP) database to identify risk factors associated with developing acute compartment syndrome (ACS) following lower extremity fractures. Specifically, a nomogram of variables was constructed in order to propose a risk calculator for ACS following lower extremity trauma. Methods: A large retrospective case-control study was conducted using the TQIP database to identify risk factors associated with developing ACS following lower extremity fractures. Multivariable regression was used to identify significant risk factors and subsequently, these variables were implemented in a nomogram to develop a predictive model for developing ACS. Results: Novel risk factors identified include venous thromboembolism prophylaxis type particularly unfractionated heparin (odds ratio [OR], 2.67; 95% confidence interval [CI], 2.33-3.05; P<0.001), blood product transfusions (blood per unit: OR 1.13 [95% CI, 1.09-1.18], P<0.001; platelets per unit: OR 1.16 [95% CI, 1.09-1.24], P<0.001; cryoprecipitate per unit: OR 1.13 [95% CI, 1.04-1.22], P=0.003). Conclusions: This study provides evidence to believe that heparin use and blood product transfusions may be additional risk factors to evaluate when considering methods of risk stratification of lower extremity ACS. We propose a risk calculator using previously elucidated risk factors, as well as the risk factors demonstrated in this study. Our nomogram-based risk calculator is a tool that will aid in screening for high-risk patients for ACS and help in clinical decision-making.

• Journal of Chest Surgery
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• v.38 no.11 s.256
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• pp.746-760
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• 2005

Background: Following the implantation of heart valve prostheses, it is important to maintain therapeutic INR to reduce the risk of thromboembolism. The objectives of this study were to determine the causes of nontherapeutic INRs, and to identify the factors associated with nonadherences to warfarin therapy in Korean outpatients with prosthetic heart valves managed by a pharmacist-run anticoagulation service (ACS). Material and Method: A retrospective chart review was completed for all patients enrolled in the ACS at Seoul National University Hospital from March, 1997b to September, 2000. The data on 868 patients (5,304 visits) who were at least 6 months post-valve replacement were included. All possible causes of nontherapeutic INRs were documented for each patient visit. The association of covariates to noncompliance was investigated by univariate analysis. Result: The reasons for nontherapeutic INRs were identified as follows: inadequate dosage adjustment $(21\%)$, nonadherences to dosing regimen $(13\%)$, drug/herbal interactions $(12\%)$, changes in diet $(7\%)$, and indeterminate cause $(42\%)$. Younger age, shorter duration of ACS and longer duration of warfarin therapy were associated with nonadherence. Conclusion: In this study, nonadherence and interactions between diet and medications were found to be important factors influencing nontherapeutic INRs. Longer duration of enrollment in the ACS affected the adherence to warfarin therapy Positively whereas younger age and longer duration of warfarin therapy affected negatively.

• Magazine of the Korea Concrete Institute
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• v.14 no.5
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• pp.27-30
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• 2002

ACS(Automatic Climbing System) 거푸집은 당 현장에서 코어 월 철근 콘크리트 공사시 사용되는 대형 거푸집으로써 상대 플로우 잭에 의해 자동으로 1개 층씩 상승되는 시스템으로 안전난간 및 안전발판을 설치하여 추락, 낙하재해에 대비하였으며 외부에 천막을 설치하여 비산먼지, 소음 등을 방지할 수 있도록 설치/운영 중이다. (그림 1)은 ACS 거푸집의 구성을 나타내었다.(중략)

• Journal of Korean Association for Spatial Structures
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• v.6 no.1 s.19
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• pp.83-90
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• 2006

The GF(Gust Factor) method is usually used as a method to evaluate equivalent static wind loads for general structures. The GF method is performed on the assumption that the shape of the equivalent static wind load profile is typically similar to that of mean wind loads. The shape of fluctuating wind loads could be quite different with that of the mean wind loads in case of large-span structures. So, the effect of higher modes as well as first mode must be considered to evaluate the wind loads. In this study, the ACS (Advanced Conditional Sampling) method is suggested to evaluate of equivalent static wind loads after investigating about GF and LRC method. The An method ran derive effective static wind loads by combining wind pressures and inertia forces of a structure chosen at a maximum load effect. The maximum load effect is assessed with the time history analysis using pressure data measured in wind tunnel tests. Equivalent static wind loads evaluated using ACS, GF, and LRC methods are compared to verify the effectiveness of ACS method.

• 전자공학회논문지 IE
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• v.45 no.4
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• pp.11-18
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• 2008

This study is implementation of attitude control system(ACS - Attitude Control System). for a multi legs robot. This study designs H/W of Inertial Measurement Unit (IMU) and attitude control algorithm S/W. Compare performance with Mtx and MTx in order to verify action performance of this system after implementation, and will verify a system integrated IMU of a multi-legs robot. ACS uses Gyro and an accelerometer and an earth magnetism sensor, and it is a system controlling a roll, pitch angle attitude of an object. Generally, low price MEMS is difficult to calculate a correct situation of an object as an error occurs severely the Inertial sensor. This study implements IMU in order to develop ACS as use MEMS, accelerometer, Gyro sensor and earth magnetism sensor. Design algorithm each a roll, pitch, yaw attitude guaranteeing regular performance, and do poling in a system as include an attitude calculation program in an IMU system implemented. Mixed output of Gyro and an accelerometer, and recompensed a roll, pitch angle, and loaded in this study on a target platform in order to implement the ACS which guaranteed performance more than a continuously regular level, and operated by real time, and did porting, and verified.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.2
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• pp.41.1-41.1
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• 2015

허블우주망원경에 장착된 ACS/WFC로 획득한 Anderson 등과 Sarajedini 등의 깊고 균질한 VI 측광 목록을 이용하여 우리은하 구상성단 M13(NGC 6205)과 M22(NGC 6656)의 뜨겁고 밝은 백색왜성 탐사를 수행하였다. 허블우주망원경 VI 측광 목록으로부터 M13과 M22의 V 대 V-I 색-등급도를 작성하였고 여기에서 많은 항성으로 잘못 검출된 대상(spurious detection)을 측광 질매개변수 qfit(V)와 qfit(I)에 따라서 제거하였다. 그리고 M13의 경우에는 중심의 높은 밀집도에 기인한 높은 측광오차를 가진 중심영역 별을 제거하기 위하여 성단 중심으로부터의 추가적인 반경 제한을 실시하였다. 이렇게 도출한 M13과 M22의 각각의 V 대 V-I 색-등급도에서 십여개 정도의 백색왜성 후보를 동정하였다. 이들은 동반되어 제공되는 ACS/WFC 각각의 영상에서 항성체로 동정되었으며, M13과 M22의 성단 중심부 영역에 임의적으로 분포하고 있으며, 색-등급도상의 위치가 DA 백색왜성 냉각계열의 밝은 부분에 위치하고 있어서 이들이 M13과 M22의 진짜 백색왜성임을 나타내고 있다. 이들에 대해 추가적으로 분광학적인 관측 연구를 수행한다면 이들의 백색왜성 진위 여부와 다양한 물리량을 밝혀낼 것이다. 또한 가까운 구상성단에 대해서 같은 방법으로 조사를 수행하면 더 많은 구상성단에서 갓 태어난 뜨겁고 밝은 백색왜성을 찾아낼 것으로 기대한다.

• Journal of Electrochemical Science and Technology
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• v.10 no.4
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• pp.387-393
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• 2019

Activated carbons (ACs) are considered important electrode materials for supercapacitors because their large specific surface areas lead to high charging capacities. In the conventional synthesis of ACs, a substantial amount of carbon is lost during carbonization of a precursor. The development of a method to synthesize ACs in high yield would lower their manufacturing cost. Here, we demonstrate the synthesis of high-specific-surface-area NaOH-AC from carbon prepared via a hydrothermal carbonization (HTC) route, with a higher yield than that achieved through conventional pyrolysis carbonization. The amorphous carbon was derived from HTC of sugar and subsequently activated at 800℃ with various NaOH etchant/C ratios under a N₂ atmosphere. The AC prepared at 4:1 NaOH/C exhibited the highest surface area (as high as 2,918 ㎡ g^-1) and the highest specific capacitance (157 F g^-1 in 1 M aqueous Na₂SO₄ electrolyte solution) among the NaOH-AC samples prepared in this work. On the basis of their high specific capacitance, the NaOH-ACs prepared from HTC sugar are suitable for use as electrode materials for supercapacitors.

• Journal of the Korean Society for Precision Engineering
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• v.29 no.4
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• pp.380-385
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• 2012

This paper contains the optimized M2M technology, and the information of production resource of 4M, which understanding the roles and functions of M2M Device, and the explanation of its effectiveness, and the information of optimized M2M Device in IT convergence point of view. In addition, this content also points out the optimized M2M Device, analyzes and collects various type of management information which emphasizes the need for a common platform's were Middleware, and Auto-Configuration, WebLine Monitoring, WebService through the functionality of an integrated management information supports the productions by digitizing the information with standardized data for management efficiency.

• Horticultural Science & Technology
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• v.32 no.2
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• pp.261-268
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• 2014

Senescence of Hosta ventricosa flowers was firstly characterized as ethylene-sensitive since the deterioration of the tepal was accompanied by increased endogenous ethylene biosynthesis. The full-length cDNAs and DNAs of 1-aminocyclopropane-1-carboxylic acid (ACC) synthase (ACS) and ACC oxidase (ACO) involved in ethylene biosynthesis were cloned from H. ventricosa flowers. The HvACS ORF with 1347 bp and two introns, encoded a polypeptide of 448 amino acids showing 79% homology with that in Musa acuminata. The HvACO ORF contained 957 bp and three introns, encoding a 318-residue polypeptide showing 83% homology with that in Narcissus tazetta. The timing of the induction of HvACS expression was in correspond to the timing of the increase in ethylene production, and that the up-regulation of HvACO transcript was closely correlated with an elevated ethylene production, but underwent a down-regulation in wounded leaves with elevated ethylene emission. The results, together with expression analysis in vegetative tissues, suggested that both HvACS and HvACO were specifically regulated by flower senescence.