• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권6호
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• pp.530-543
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• 2006

Adeonoid cystic carcinoma (ACC) is one of the most common malignant tumors of salivary glands. It is characterized by a relentless regrowth especially around nerve tissues and a high rate of hematogenous distant metastasis. Clinically most deaths from salivary ACC are caused by delayed lung metastases that are resistant to conventional chemotherapy. So, knowledge of cellular and molecular properties that influence the dissemination of metastatic tumor cells, is important for new treatment strategies of metastatic lesions. We determined expressions of angiogenic signaling molecules microvessel density (MVD) using surgical specimens of human salivary ACC. Protein expressions of vascular endothelial growth factor (VEGF), VEGF receptor (VEGFR)-2, activated VEGFR-2, and human CD31 were assessed in 20 cases of salivary ACC by immunohistochemical staining. Most of the tumors, especially ACC with a tubulocribriform pattern, were positive for antibodies of VEGF, VEGFR-2, and activated VEGFR-2. The overall percentages of the 20 specimens expressing VEGF, VEGFR-2, activated VEGFR-2 were 90, 95, and 95%, respectively. Immunoreactivities of the biomarkers in salivary ACC were higher than those in normal salivary gland. Furthermore, immune-related cells as well as tumor cells expressed VEGF/VEGFR-2. Microvessel density of salivary ACC was higher than that of normal salivary gland (P<0.05). Taken together, angiogenic signaling molecules are actively expressed in salivary ACC. And we suggest that these molecules may have critical role in the hematogenous spread of salivay ACC, which has a propensity for delayed lung metastasis. Therefore, these biomarkers can be molecular targets for therapy of metastasis of salivary ACC.

• 한국인터넷방송통신학회논문지
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• 제13권5호
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• pp.1-8
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• 2013

본 논문에서는, 차량 섀시 제어시스템 중 ACC(Adaptive Cruise Control)와 LKS(Lane Keeping System)를 통합하여 차량용 OS인 OSEK OS 기반으로 구현하고 실험을 통하여 그 성능을 분석한다. 최근 자동차의 안전성을 향상시키기 위해 능동 안전 및 운전자 지원 시스템이 논의 되고 있다. 그 중 차량의 종방향에 대한 가감속 제어를 수행하는 ACC와 차량이 차선을 유지할 수 있도록 보조해주는 LKS를 통합하여 차량 내 제어시스템을 구현한다. 구현한 제어시스템은 차량용 소프트웨어의 재사용성과 안전성 및 응용 소프트웨어의 하드웨어 의존성 제거 등을 목표로 표준 제안된 OSEK/VDX를 적용한다. OSEK/VDX에서 지원하는 OSEK OS를 기반으로 재설계한 제어시스템은 실시간 태스크 관리와 인터럽트 처리 및 공유자원 관리가 가능하다. EILS(ECU-In-the-Loop Simulation) 수행 결과에 의해 OSEK OS 기반의 ACC/LKS 통합제어기와 기존 일체형 펌웨어로 구현한 ACC/LKS 통합제어기가 대등함을 입증한다.

• Journal of Microbiology and Biotechnology
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• 제18권5호
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• pp.958-963
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• 2008

A series of experiments were conducted to assess the effectiveness of rhizobacteria containing 1-aminocyclopropane-1-carboxylate (ACC) deaminase for growth promotion of peas under drought conditions. Ten rhizobacteria isolated from the rhizosphere of different crops (peas, wheat, and maize) were screened for their growth promoting ability in peas under axenic condition. Three rhizobacterial isolates, Pseudomonas fluorescens biotype G (ACC-5), P. fluorescens (ACC-14), and P. putida biotype A (Q-7), were selected for pot trial on the basis of their source, ACC deaminase activity, root colonization, and growth promoting activity under axenic conditions. Inoculated and uninoculated (control) seeds of pea cultivar 2000 were sown in pots (4 seeds/pot) at different soil moisture levels (25, 50, 75, and 100% of field capacity). Results revealed that decreasing the soil moisture levels from 100 to 25% of field capacity significantly decreased the growth of peas. However, inoculation of peas with rhizobacteria containing ACC deaminase significantly decreased the "drought stress imposed effects" on growth of peas, although with variable efficacy at different moisture levels. At the lowest soil moisture level (25% field capacity), rhizobacterial isolate Pseudomonas fluorescens biotype G (ACC-5) was found to be more promising compared with the other isolates, as it caused maximum increases in fresh weight, dry weight, root length, shoot length, number of leaves per plant, and water use efficiency on fresh and dry weight basis (45, 150, 92, 45, 140, 46, and 147%, respectively) compared with respective uninoculated controls. It is highly likely that rhizobacteria containing ACC deaminase might have decreased the drought-stress induced ethylene in inoculated plants, which resulted in better growth of plants even at low moisture levels. Therefore, inoculation with rhizobacteria containing ACC deaminase could be helpful in eliminating the inhibitory effects of drought stress on the growth of peas.

• 한국작물학회지
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• 제30권2호
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• pp.184-189
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• 1985

질소수준이 높아짐에 따라서 벼 엽신에서 에칠렌 생성량이 감소하는 원인에 대하여 에칠렌생합성계에 존재하는 전구물질 메치오닌 및 직접전구물질 ACC등을 벼에 처리하여 에칠렌생성량에 미치는 영향을 검토한 결과를 요약하면 다음과 같다. 1. 벼 유묘 및 엽에 메치오닌을 처리하면 처리농도가 높을수록 에칠렌생성량은 증가하였다. 2. 직접전구물질인 ACC를 엽신에 처리하면 처리농도가 높을수록 에칠렌생성량은 직선적으로 증가하였다. 3. 질소수준이 다를 벼의 유묘 및 엽신에 메치오닌 및 ACC를 처리하면 에칠렌생성량은 증가하나 질소수준이 높아질수록 에칠렌생성량은 현저히 억제 되어진다.

• Smart Structures and Systems
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• 제17권3호
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• pp.391-411
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• 2016

This study investigates the mode identifiability of a multi-span cable-stayed bridge in terms of a benchmark study using stabilization diagrams of a system model identified using stochastic subspace identification (SSI). Cumulative contribution ratios (CCRs) estimated from singular values of system models under different wind conditions were also considered. Observations revealed that wind speed might influence the mode identifiability of a specific mode of a cable-stayed bridge. Moreover the cumulative contribution ratio showed that the time histories monitored during strong winds, such as those of a typhoon, can be modeled with less system order than under weak winds. The blind data Acc 1 and Acc 2 were categorized as data obtained under a typhoon. Blind data Acc 3 and Acc 4 were categorized as data obtained under wind conditions of critical wind speeds around 7.5 m/s. Finally, blind data Acc 5 and Acc 6 were categorized as data measured under weak wind conditions.

• Journal of Plant Biology
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• 제33권4호
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• pp.309-314
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• 1990

Effect of mannose on auxin-induced ethylene production in corn (Zea mays L.) coleoptiles was studied. Auxin induced ethylene production decreased in proportion to mannose concentrations. The inhibitory effect of mannose appeared after 2 h of incubation. Ethylene production was significantly depressed by mannose at high concentration (10-5M-10-4M) of indole acetic acid (IAA), but not at low concentrations (10-8M-10-6M). The inhibition of auxin-induced ethylene production by mannose was specific, since other sugars such as galactose, glucose, sucrose and mannitol did not have an inhibitory effect. In an effort to elucidate mechanisms of mannose the effect on the auxin induced ethylene production, effect of the sugar on ACC synthase activity and ACC induced ethylene production was studied. Mannose failed to inhibit ACC mediated ethylene production, but decreased both the ACC content and ACC synthase activity in the tissue. These results suggest that the inhibitory effect of mannose on auxin induced ethylene production results from suppression of auxin induction of ACC synthase.

• 한국식물학회:학술대회논문집
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• 한국식물학회 2002년도 춘계학술발표대회:발표눈문요지록
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• pp.96-96
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• 2002

• Journal of Microbiology and Biotechnology
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• 제25권7호
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• pp.1119-1128
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• 2015

1-Aminocyclopropane-1-carboxylate (ACC) deaminase, which is encoded by some bacteria, can reduce the amount of ethylene, a root elongation inhibitor, and stimulate the growth of plants under various environmental stresses. The presence of ACC deaminase activity and the regulation of ACC in several rhizospheric bacteria have been reported. The nitrogen-fixing Pseudomonas stutzeri A1501 is capable of endophytic association with rice plants and promotes the growth of rice. However, the functional identification of ACC deaminase has not been performed. In this study, the proposed effect of ACC deaminase in P. stutzeri A1501 was investigated. Genome mining showed that P. stutzeri A1501 carries a single gene encoding ACC deaminase, designated acdS. The acdS mutant was devoid of ACC deaminase activity and was less resistant to NaCl and NiCl₂ compared with the wild-type. Furthermore, inactivation of acdS greatly impaired its nitrogenase activity under salt stress conditions. It was also observed that mutation of the acdS gene led to loss of the ability to promote the growth of rice under salt or heavy metal stress. Taken together, this study illustrates the essential role of ACC deaminase, not only in enhancing the salt or heavy metal tolerance of bacteria but also in improving the growth of plants, and provides a theoretical basis for studying the interaction between plant growth-promoting rhizobacteria and plants.

• 전자공학회논문지CI
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• 제48권6호
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• pp.1-8
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• 2011

멀티미디어 핑거프린팅 분야에서 반공모에 강한 탄력성을 갖는 BIBD(Balanced Incomplete Block Design) 기반의 코드가 많이 사용된다. BIBD 기반의 코드를 논리적 XOR연산으로 공모공격 코드를 생성할 때, 공모된 코드가 비공모자의 원 핑거프린팅 코드와 동일하게 생성이 된 경우가 발생할 수 있다. 이에 따라 비공모자가 공모자로 판정이 되며, 반면에 공모자가 비공모자로 판정되어 공모자 추적에서 제외될 수 있다. 본 논문에서는 심각한 오판정의 공모자추적 문제를 해결하기 위하여, 상관계수 측정에 의한 (AND, OR, XOR and Averaging)-ACC(Anti-Collusion Code)에서 XOR-ACC를 다층 퍼셉트론의 신경망을 이용한 알고리즘을 구현한다. 실험을 통하여, BIBD 기반의 {7,3,1} 멀티미디어 핑거프린팅 코드의 XOR-ACC의 효율성이 기존의 41.18%에서 88.24%로 향상되어 공모자 추적율도 기존의 53%에서 100%로 향상되었음을 확인하였다. 그 결과 공모공격에 대한 공모자와 비공모자의 구분을 완전하게 추적과 판정을 할 수 있다.

• 한국정보전자통신기술학회논문지
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• 제15권3호
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• pp.189-197
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• 2022

고성능 컴퓨팅 기술이 발달하고 수치 모델 방식이 고도화됨에 따라 더욱 우수한 기상예보를 진행할 수 있게 되었다. 본 논문에서는 SCAM 기상 모델에 대하여 컴파일 시간을 제외한 모델 수행시간에 대한 성능 향상을 끌어내는 것이 목적이다. 따라서, 기존의 Intel Fortran Compiler를 이용하여 수행된 모델을 PGI Fortran Compiler로 변경하였다. 이를 위해 시스템 환경 변수 재설정, 컴파일 옵션 조정, 관련 의존성 SW 및 라이브러리 설치 그리고 소스 코드를 수정하였다. 또한, 본 논문에서 제안한 PGI Compile with OpenACC 방법을 제시하고 적용하였다. 그 결과 러닝 시간의 경우 기존 Intel에서 PGI로 컴파일러가 변경되면, 러닝 시간의 경우 6.08%의 성능 향상이 되었으며, OpenACC를 추가로 적용할 경우, 기존 대비 43.05%의 성능 향상을 보여준다. 이는 본 논문에서 제안한 SCAM모델에서 PGI Compile with OpenACC 방법이 우수한 성능을 보여줄 수 있음을 입증한다.