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Single or Dual Infection with Respiratory Syncytial Virus and Human Rhinovirus: Epidemiology and Clinical Characteristics in Hospitalized Children in a Rural Area of South Korea (호흡기세포융합바이러스와 라이노바이러스의 단독 혹은 동시감염의 역학 및 임상적 특성: 강원 지역 단일 기관의 후향적 연구)

  • Kwon, Yerim;Cho, Won Je;Kim, Hwang Min;Lee, Jeongmin
    • Pediatric Infection and Vaccine
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    • v.26 no.2
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    • pp.99-111
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    • 2019
  • Purpose: Respiratory syncytial virus (RSV) and human rhinovirus (hRV) are the most common causes of child respiratory viral infections. We aimed to investigate epidemiological and clinical characteristics of RSV and hRV single infections and coinfections. Methods: Nasopharyngeal aspirates of hospitalized children aged <5 years were tested using multiplex reverse transcription polymerase chain reaction (RT-PCR) from October 2014 to April 2017. Their medical records were retrospectively reviewed. Results: RSV or hRV was detected in 384 patients who divided into 3 groups: patients with RSV (R group, n=258); patients with hRV (H group, n=99); and patients with both (RH group, n=27). The R group (median age, 6 months) consisted of 248 (96.1%) patients with lower respiratory tract infection (LRTI), and 14 (5.4%) needed oxygen inhalation. Infants aged <12 months (63.2%) had respiratory difficulty and were supplied oxygen more often. The H group (median age, 16 months) consisted of 56 (56.6%) patients with LRTI, 4 (4%) required oxygen inhalation, and 1 (1.0%) required mechanical ventilation. Infants (40.4%) showed longer hospitalization compared to patients aged ${\geq}12$ months (5 vs. 4 days, P<0.05). The RH group consisted of 24 (88.9%) patients with LRTI, and 2 (7.4%) needed oxygen inhalation. Hospitalization days and oxygen inhalation and mechanical ventilation rates did not differ between single infections (R and H groups) and coinfections (RH group). Conclusions: RSV was detected more often in younger patients and showed higher LRTI rates compared to hRV. Single infections and coinfections of RSV and hRV showed no difference in severity.

Utility Evaluation of Supportive Devices for Interventional Lower Extremity Angiography (인터벤션 하지 혈관조영검사를 위한 보조기구의 유용성 평가)

  • Kong, Chang gi;Song, Jong Nam;Jeong, Moon Taek;Han, Jae Bok
    • Journal of the Korean Society of Radiology
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    • v.13 no.4
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    • pp.613-621
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    • 2019
  • The purpose of this study is to evaluate the effectiveness of supportive devices which are for minimizing the patient's movement during lower extremity angiography and to verify image quality of phantom by analyzing of Mask image, DSA image and Roadmap image into SNR and CNR. As a result of comparing SNR with CNR of mask image obtained by DSA technique using the phantom alone and phantom placed on the supportive devices, there was no significant difference between about 0~0.06 for SNR and about 0~0.003 for CNR. The study showed about 0.11~0.35 for SNR and 0.016~0.031 for CNR of DSA imaging by DSA technique about only water phantom of the blood vessel model and the water phantom placed on the device. Analyzing SNR and CNR of Roadmap technique about water phantom on the auxiliary device (hardboard paper, pomax, polycarbonate, acrylic) and water phantom alone, there was no significant difference between 0.02~0.05 for SNR and 0.002~0.004 for CNR. In conclusion, there was no significant difference on image quality by using supportive devices made by hardboard paper, pomax, polycarbonate or acryl regardless of whether using supportive devices or not. Supportive devices to minimize of the patient's movement may reduce the total amount of contrast, exam-time, radiation exposure and eliminate risk factors during angiogram. Supportive devices made by hardboard paper can be applied easily during angiogram due to advantages of reasonable price and simple processing. It is considered that will be useful to consider cost efficiency and types of materials and their properties in accordance with purpose and method of the study when the operator makes and uses supportive devices.

The Character of Bogamni group and trends in the surrounding area seen through the stone chamber (석실로 본 나주 복암리 세력과 주변 지역의 동향)

  • Kim, Nak jung
    • Korean Journal of Heritage: History & Science
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    • v.49 no.1
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    • pp.44-67
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    • 2016
  • This article studied the character of Bogamri group and trends in the surrounding area through recently excavated stone chambers. The first type of stone chamber constructed at Bogamni cemetry was Northen Kyushu style stone chamber tomb with corridor. However, According to recent survey Wa style vertical stone lined tomb had constructed earlier than these stone chamber along the southwest cost. It is likely that the background of these Wa style stone tomb was the beginning of formal diplomatic relations between Baekje and Wa. At first, grave goods as well as burial had been Wa style, but gradually local burial element and mortuary practices added. And large tomb had beginning to appear. The representative tombs are Yeongam Okyari Jangdong tomb and Naju Gaheugni Shinhueng tomb. They were built in the middle of the fifth century. It is most likely that the location was selected with regard to the use or securing of inland waterway. But the next step, Yeongsangang river style stone chamber with corridor had constructed at Jeongchon tomb. That tomb is very close to Bogamni tombs and structure and grave goods are very similar also. So these two groups were considered to be the same community. Hereby, It is believed that the inland waterway using power had been turned over to Bogamni group. Bogamni group had constantly constructed stone chamber until seventh century. This represent that Bogamni group had thrived as a leading force in the Yeongsangang river basin. After under the direct control of Baekje, Bogamni group had continued the close relationship with Wa. For this reason, Bogamni group had influenced southwest cost as well as Yeongsangang river basin. It can be estimated by the Bogamni style stone chamber founded at islands of Shinan.

Changes in fundamental frequency depending on language, context, and language proficiency for bilinguals (한국어-영어 이중언어 화자의 사용 언어, 문맥, 언어 능숙도에 따른 기본 주파수 변화)

  • Yoon, Somang;Mok, Sora;Youn, Jungseon;Han, Jiyun;Yim, Dongsun
    • Phonetics and Speech Sciences
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    • v.11 no.1
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    • pp.9-18
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    • 2019
  • The purpose of this study is to determine whether the mean fundamental frequency (F0) changes depending on language, task, or language proficiency for Korean-English bilinguals. A total of forty-eight Korean-English speakers (28 balanced bilinguals and 20 Korean dominant bilinguals) participated in the study. Participants were asked to read aloud two types of tasks in English and Korean. For statistical analyses, the language ${\times}$ task two-way repeated ANOVAs were conducted within the balanced bilingual group first, and then group ${\times}$ language two-way mixed ANOVAs. The results showed that the females in both bilingual groups changed their mean F0 depending on the language they used and the tasks (p<.05), whereas no significant results were found in the males in either group under any conditions. The mean fundamental frequency in the Korean reading task was significantly higher than that in the English reading task for females in both balanced and Korean dominant bilingual groups. Thus, changes in mean F0 depending on language and context may reflect gender-specific characteristics, and females seem to be more sensitive to the socio-cultural standards that are imposed on them.

Earnings Quality of Firms Selected as the Global Champ Project (글로벌 전문사업 선정기업의 이익의 질)

  • Gong, Kyung-Tae
    • Management & Information Systems Review
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    • v.37 no.4
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    • pp.1-20
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    • 2018
  • This study aimed to examine earnings quality of firms selected as Global Champs project which has been promoted by the government since 2013 to support small and medium sized enterprises, for the screening year(t-1) and selected year(t). Earing quality is measured as the value of discretionary accruals estimated by Dechow et al.(1995) adjusted Jones model and Kothari et al.(2005) model, respectively. I analyze the differences of earning quality between the Global Champ firms and the paired firms selected through criteria of the similar total assets and the same industry in the screening year and the selected year. This study is motivated by the needs of measurement of the performance of the Project from the accounting transparent point of view. As the results of this study, major findings are summarized as follows. Firstly the earnings quality of the selected firms was lower than that of the paired firms. This can be explained as a result of motivation of earnings management by companies eager to meet the requirements to be selected for the Project. Secondly, in the selected year, the earnings quality was proved to improve, comparing to the screening year. This can be explained by the efforts of companies to reinforce management innovation and transparent management, which in turn led to positive effects on the earnings quality. These findings were found to be consistent in the additional analyses, where the earning quality of the reconstructed sample with only selected companies was compared for the screening year and the selected year, based on the year before the screening year(t-2).

Comparison of the Rate of Demineralization of Enamel using Synthetic Polymer Gel (합성 폴리머 겔의 법랑질 탈회 속도 비교)

  • Lee, June-Hang;Shin, Jisun;Kim, Jongsoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.2
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    • pp.190-199
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    • 2019
  • $Carbopol^{(R)}$ 907 used as surface protecting agent in White's method is the one of the artificial caries lesion producing solution was discontinuing of production. New surface protecting material to substitute of $Carbopol^{(R)}$ 907 was required. The author prepared an artificial caries lesion producing solution as follows White's method with $Carbopol^{(R)}$ 907 and also another artificial caries lesion producing solution with $Carbopol^{(R)}$ $2050^{(R)}$. 96 flattened and polished enamel samples were immersed in a demineralizing solution of 0.1 mol/L lactic acid, 0.2% carboxyvinylpolymer and 50% saturated hydroxyapatite for 1, 2, 3, 4, 5, 6, 7, 9, 11, 15, 18 and 20 days. All samples from each group were subjected to polarized microscopy observed and image analysis for measuring the lesion depth. From the review of polarized images, the artificial caries lesion producing solution using $Carbopol^{(R)}$ 907 and $Carbopol^{(R)}$ 2050 can produced an artificial caries that was very similar to natural caries characters. From the regression analysis of the lesion depth produced by the artificial caries lesion producing solution using $Carbopol^{(R)}$ 907 and $Carbopol^{(R)}$ 2050, $Carbopol^{(R)}$ 2050 estimate as Y = 9.8X + 8.0 and $Carbopol^{(R)}$ 907 was Y = 8.4X - 0.4. R square value of $Carbopol^{(R)}$ 2050 and $Carbopol^{(R)}$ 907 was 0.965 and 0.945 respectively. The rate of demineralization by the artificial caries lesion producing solution using $Carbopol^{(R)}$ 2050 was faster than that of $Carbopol^{(R)}$ 907. And R square value of $Carbopol^{(R)}$ 2050 and $Carbopol^{(R)}$ 907 were very high and it means that the lesion depth was very high coefficient to demineralization period.

Development of Analytical Method for Ergot Alkaloids in Foods Using Liquid Chromatoraphy-Tandem Mass Spectrometry (LC-MS/MS를 이용한 식품 중 맥각 알칼로이드 시험법 개발)

  • Chun, So Young;Chong, Euna;Lee, Bomnae;Kwon, Jin-Wook;Park, Hye Young;Kim, Sheenhee;Gang, Giljin
    • Journal of Food Hygiene and Safety
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    • v.34 no.2
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    • pp.158-169
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    • 2019
  • Ergot alkaloids are mycotoxin produced by fungi of the Claviceps genus, mainly by Claviceps purpurea in EU. Recently obtained informations indicates necessity for control the ergot in imported grains. Recent occurrence data of ergot alkaloids from EU countries indicate the necessities of management and control these toxins from the imported grains like rye, wheat, oat etc. The aim of this study is to optimize the liquid chromatography-tandem mass spectrometry method for determination of ergot alkaloids (ergometrine, ergosine, ergotamine, ergocornine, ergocryptine, ergocristine and their epimers (-inines) from grain and grain-based food. The test method was optimized by extracting the sample with acetonitrile containing 2 mM ammonium carbonate, purification with Mycosep cartridge, and instrumental analysis by LC-MS/MS using Syncronis C18 column. The standard calibration curves showed linearity with correlation coefficents; $R^2$ >0.99. Mean recoveries ranged from 72.0 to 111.3% at three different fortified levels (20, 50, and $100{\mu}g/kg$). The correlation coefficient expressed as precision was within the range of 1.9-12.9%. The limit or quantifications (LOQ) ranged from 0.012 to $0.058{\mu}g/kg$. The developed analytical method met the criteria of AOAC Int. and CAC validation parameters like accuracy and sensitivity. As a result, it was confirmed that the test method developed in this study is suitable for the simultaneous analysis of six species of ergot alkaloid from grains and grain products.

A Study on the Characteristics of Commemoration in the World War II Cemeteries - Focus on the Military Cemeteries of United States, the Commonwealth, and Germany in Western Europe - (제2차 세계대전 전쟁 묘지에 나타난 기념성 - 서유럽에 있는 미국군, 영연방군, 독일군 묘지를 대상으로 -)

  • Lee, Sang-Seok
    • Journal of the Korean Institute of Landscape Architecture
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    • v.49 no.5
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    • pp.97-111
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    • 2021
  • The purpose of this study was to analyze commemoration characteristics of the United States of America, the Commonwealth, and Germany through representative 14 military cemeteries of World war II in Western Europe. Based on the commemoration characteristics such as spacial characteristic, commemorative elements, and graves and headstone, the commemoration culture among U.S., the Commonwealth. and Germany were studied comparatively. The results are as follows. First, taking geometrical form with mainly square type, rarely circle and spiral patterned, most cemeteries were structured spatial central axis with symmetry, those cemeteries were styled neoclassical, but some of the U.S. cemeteries were modernistic, connecting spaces organically with curved line layout. Second, chapel, the wall of missing, the wall of battle map, and sculpture in the U.S military cemeteries, and 'the cross of sacrifice' and 'the stone of remembrance' as classical monument in the Commonwealth war cemeteries were commonly applied standardized commemorative elements, but commemorative monuments in German military cemeteries were restricted except monumental cross. Third, the symbolic cross of christianism was used all cemeteries to console and cherish the soul of soldiers, specially the Latin crosses in the U.S military cemeteries delivered political message as the american martyr for Western Europe and also the power of the U.S., but the cross in German and the Commonwealth war cemeteries were basically cherish and comfort individual spirit. Fourth, showing the power of victory with national patriotism, the U.S. strongly represented christianism and liberal democracy against communism, the Commonwealth showed imperialistic style, and German military cemeteries were quietly appeared as traditional style forwarding reconciliation and peace. This study suggest the war cemeteries have national identity with typical form and symbolic aesthetics. Further study will be required to materialize sublime commemoration in national cemeteries and to form advanced commemorative culture in Korea.

A Study on Containerports Clustering Using Artificial Neural Network(Multilayer Perceptron and Radial Basis Function), Social Network, and Tabu Search Models with Empirical Verification of Clustering Using the Second Stage(Type IV) Cross-Efficiency Matrix Clustering Model (인공신경망모형(다층퍼셉트론, 방사형기저함수), 사회연결망모형, 타부서치모형을 이용한 컨테이너항만의 클러스터링 측정 및 2단계(Type IV) 교차효율성 메트릭스 군집모형을 이용한 실증적 검증에 관한 연구)

  • Park, Ro-Kyung
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.9 no.6
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    • pp.757-772
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    • 2019
  • The purpose of this paper is to measure the clustering change and analyze empirical results, and choose the clustering ports for Busan, Incheon, and Gwangyang ports by using Artificial Neural Network, Social Network, and Tabu Search models on 38 Asian container ports over the period 2007-2016. The models consider number of cranes, depth, birth length, and total area as inputs and container throughput as output. Followings are the main empirical results. First, the variables ranking order which affects the clustering according to artificial neural network are TEU, birth length, depth, total area, and number of cranes. Second, social network analysis shows the same clustering in the benevolent and aggressive models. Third, the efficiency of domestic ports are worsened after clustering using social network analysis and tabu search models. Forth, social network and tabu search models can increase the efficiency by 37% compared to that of the general CCR model. Fifth, according to the social network analysis and tabu search models, 3 Korean ports could be clustered with Asian ports like Busan Port(Kobe, Osaka, Port Klang, Tanjung Pelepas, and Manila), Incheon Port(Shahid Rajaee, and Gwangyang), and Gwangyang Port(Aqaba, Port Sulatan Qaboos, Dammam, Khor Fakkan, and Incheon). Korean seaport authority should introduce port improvement plans by using the methods used in this paper.

Functional screening of Asparagus officinalis L. stem and root extracts (아스파라거스 줄기 및 뿌리 추출물의 기능성 검증)

  • Han, Joon-Hee;Hong, Min;Lee, Jaehak;Choi, Da-Hye;Lee, Sun-Yeop;Kwon, Tae-Hyung;Lee, Jae-Hee;Lee, Yong-Jin;Yu, Keun-Hyung
    • Korean Journal of Food Science and Technology
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    • v.53 no.1
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    • pp.46-54
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    • 2021
  • The biological activities of non-edible extracts of asparagus stems and roots were investigated using hot water and ethanol. The highest contents of rutin and total polyphenol were 31.74 mg/g and 20.14 mg GAE/g, respectively, in the stem hot water extract. ABTS and DPPH radical scavenging activities were 541.1±21.0 and 649.5±6.6 ㎍/mL, respectively, in stem hot water extract. All extracts were non-cytotoxic in HepG2 cells, but 200 ㎍/mL stem extracts tended to decrease the viability of RAW 264.7 cells. The highest xanthine oxidase inhibitory activity was 43.68% in the root hot water extract at 200 ㎍/mL. The expression level of MMP-9 was significantly decreased in the asparagus extracts. The highest GGT, AST, and LDH activities showed a concentration-dependent decrease in the stem ethanol extract. In conclusion, the presence of bioactive substances in the non-edible extracts of asparagus was confirmed for the development of extracts with antioxidant, hepatoprotective and anti-gout activities.