• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3635-3640
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• 2014

Aim: To determine whether induced abortion (IA) increases breast cancer (BC) risk. Materials and Methods: A population-based case-control study was performed from Dec, 2000 to November, 2004 in Shanghai, China, where IA could be verified through the family planning network and client medical records. Structured questionnaires were completed by 1,517 cases with primary invasive epithelial breast cancer and 1,573 controls frequency-matched to cases for age group. The information was supplemented and verified by the family planning records. Statistical analysis was conducted with SAS 9.0. Results: After adjusting for potential confounders, induced abortions were not found to be associated with breast cancer with OR=0.94 (95%CI= 0.79-1.11). Compared to parous women without induced abortion, parous women with 3 or more times induced abortion (OR=0.66, 95%CI=0.46 to 0.95) and women with 3 or more times induced abortion after the first live birth (OR=0.66, 95%CI =0.45 to 0.97) showed a lower risk of breast cancer, after adjustment for age, level of education, annual income per capita, age at menarche, menopause, parity times, spontaneous abortion, age at first live birth, breast-feeding, oral contraceptives, hormones drug, breast disease, BMI, drinking alcohol, drinking tea, taking vitamin/calcium tablet, physical activity, vocation, history of breast cancer, eating the bean. Conclusions: The results suggest that a history of induced abortions may not increase the risk of breast cancer.

• 자원리싸이클링
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• 제5권3호
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• pp.56-64
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• 1996

탄산칼슘의 다형 제어를 목적으로 합성 음료, 의약품 등으로서도 폭넓게 이용되고 있는 ${C_2}{H_4}{OH}$계에서 수산화칼슘을 현탁시키고 감미제, 의약품 등의 용도로서도 이용되고 있는 에틸렌글리콜을 첨가하면서 탄산칼슘 생성 및 탄산칼슘 다형결정화 특성에 대해 연구하였다. 세라믹 bubble plate를 부착 제작한 반응기를 사용하여 $CO_2$gas와 반응 진행시 전기전도도의 연속 측정을 통해 변화시점에서 일부 현탁액을 분리 분말화하여 X선 회절 및 전자현미경을 통해 중가 생성물과 이들이 각각 Vaterite, Aragonite, Calcite로 전이됨을 확인하였다. ${C_2}{H_4}{OH}$에 대한 에틸렌글리콜 첨가를 10 vol%로 하여 500ml의 반응 현탁액에 10~50g의 수산화칼슘 첨가 변화에 따른 생성물을 조사하였다. 결정화단계에서 수산화칼슘 10g 첨가시를 제외하고는 모든 조건에서 겔화(gelation)가 일어나며 그 생성 유지시간은 수산화칼슘 양이 많아질수록 짧아짐을 관찰할 수 있었다. 상온 상압하에서 생성되기 어려웠던 Vaterite가 $Ca(OH)_2$의 30g 첨가반응계에서 구형으로 생성됨을 확인할 수 있었다. 이는 칼슘계, 흡착제 등의 가능성을 부여한 복합재료로서의 Vaterite 합성을 상온 상압화에서${C_2}{H_4}{OH}$ 계에서 다형제어 할 수 있음을 보여주었다. 탄산칼슘의 동질이상중 Vaterite는 준안정상이고 분말화 과정에서 이미 Calcite로 전이되기 쉬우나 G5 glass filter와 vacuum drier를 사용하여 안정적인 구형의 Vaterite을 확인할 수 있었다.

• 한국실내디자인학회논문집
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• 제19권6호
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• pp.150-160
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• 2010

The origin of the Roman public basilica is Rome's indigenous style morphologically but actually it seems that developed the Greek semi-open style stoa into the Roman practical interior space. In the early ages, the arrangement of Roman forum had been planned high symbolical temple as the center but gradually changed into the basilica centered which were used often by citizen. Through the Roman period, the important types of early Roman basilica have Fano basilica in the first century BC, Pompei basilica of mid period in the first century AD, Doclear basilica with apse as late type in the second century AD. Pompei type well characterized the feature of Roman public basilica among them. The result of the floor plan analysis shows that the long side access to the interior space is over 76 percent of examples and nearly 70 percent have no apse and the average of vertical horizontal length ratio presents as 1:2.3. The typical plan of Roman public basilica can be defined that most of access are being entered from one of the long side, and most of basilica have no apse, and normally having inner columns arranged in one or more concentric rectangles around nave as a center.

• 한국관개배수논문집
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• 제17권2호
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• pp.3-16
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• 2010

The subject of externality of agricultural water supply has been discussed in the OECD AC ( Organization for Economic Cooperation and Development Agriculture Committee) while argued between monsoon Asian developing countries and the agricultural product export nations (Australia, EU, etc). It argued that a 'positive' approach to multifunctionality views agriculture as an economic activity with multiple, interconnected outputs or effects, and a 'normative' approach interprets multifunctionality in terms of the multiple roles assigned to agriculture. and the agricultural product export nations insisted 'negative' approach to externality of agricultural water supply like causing water pollution. So, in this study, define the externalities (positive, negative and economic, environmental) in terms of the agricultural water supply and calculate benefit and cost each the externalities by cost estimation. As results, BC is calculated to 1.28 which means that it is more economical to agricultural water supply and shows that although the negative exernalities comes out while supply the agricultural water, it still more valuable to supply the agricultural water.

• 한국자기학회지
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• 제22권4호
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• pp.142-146
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• 2012

자석에 대한 인간의 관심은 긴 역사를 가지고 있으며, 또한 자석을 바라보는 시선도 다양했다. 과거에는 과학자의 시선이 아니라 철학자의 눈으로 바라다 보기도 하였다. 이 글에서는 과거 우리나라에서 자석을 어떻게 인식해왔는가를 다루어보고자 한다. 자석과 관련된 내용을 시기적으로 분류해 보면 1) 자성(磁性)의 인식기 2) 극성(極性)의 인식기 3) 근대지식의 유입기로 나눌 수 있다. 한국사 전체에서 보면, 신라에서 자석을 생산하였다는 기록을 찾을 수 있었으며 고려시대 기록에서는 자석에 관한 자료를 찾을 수 없었다. 자석에 대한 관심은 조선시대에 들어와서 고조된 것으로 보인다. 그 중에서도 풍수 즉 양택과 음택의 입지와 관련하여 가장 많이 이용되었다. 조선시대에는 항해에 자석을 사용하였다는 기록도 확인된다. 그밖에 의외의 사용처로는 약재의 일부로 쓴 경우를 볼 수 있다.

• Journal of electromagnetic engineering and science
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• 제18권3호
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• pp.188-198
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• 2018

In this study, we propose an approach for the design and satisfy the requirements of the fabrication of a small, lightweight, reliable, and stable ultra-wideband receiver for millimeter-wave bands and the contents of the approach. In this paper, we designed and fabricated a stable receiver with having low noise figure, flat gain characteristics, and low noise characteristics, suitable for millimeter-wave bands. The method uses the chip-and-wire process for the assembly and operation of a bare MMIC device. In order to compensate for the mismatch between the components used in the receiver, an amplifier, mixer, multiplier, and filter suitable for wideband frequency characteristics were designed and applied to the receiver. To improve the low frequency and narrow bandwidth of existing products, mathematical modeling of the wideband receiver was performed and based on this spurious signals generated from complex local oscillation signals were designed so as not to affect the RF path. In the ultra-wideband receiver, the gain was between 22.2 dB and 28.5 dB at Band A (input frequency, 18-26 GHz) with a flatness of approximately 6.3 dB, while the gain was between 21.9 dB and 26.0 dB at Band B (input frequency, 26-40 GHz) with a flatness of approximately 4.1 dB. The measured value of the noise figure at Band A was 7.92 dB and the maximum value of noise figure, measured at Band B was 8.58 dB. The leakage signal of the local oscillator (LO) was -97.3 dBm and -90 dBm at the 33 GHz and 44 GHz path, respectively. Measurement was made at the 15 GHz IF output of band A (LO, 33 GHz) and the suppression characteristic obtained through the measurement was approximately 30 dBc.

• 대한의생명과학회지
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• 제10권3호
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• pp.195-202
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• 2004

Lung cancer is a leading cause of cancer death worldwide; however, despite major advances in cancer treatment during the past two decades, the prognostic outcome of lung cancer patients has improved only minimally. This is largely due to the inadequacy of the traditional screening approach of diagnosis in lung cancer, which detects only well­established overt cancers and fails to identify precursor lesions in premalignant conditions of the bronchial tree. In recent years this situation has fundamentally changed with the identification of molecular abnormalities characteristic of premalignant changes; these concern tumour suppressor genes, loss of heterozygosity at crucial sites and activation of oncogenes. Basic knowledge at the molecular level has extremely important clinical implications with regard to early diagnosis, risk assessment and prevention, and therapeutic targets. In this study we used a 'cap-finder' subtractive hybridization method, 'long distance' polymerase chain reaction (PCR), streptavidin magnetic beads mediated subtraction, and spin column chromatography to detect differential expression genes of human small cell lung carcinoma. We have now isolated ninety two genes that expressed differentially in the human small cell lung carcinoma cells and analyzed of 12 clones with sequencing, nine cDNAs include tapasin (NGS-17) mRNA, BC200 alpha scRNA, chromosome 12q24 PAC RPCI3-462E2, protein phosphatase 1 (PPPICA), translocation protein 1 (TLOC1), ribosomal protein S24 (RPS24) mRNA, protein phosphatase (PPEF2), cathepsin Z, MDM2 gene and three novel genes. They may be oncogenesis­related proteins.

• 한국대기환경학회지
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• 제22권3호
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• pp.287-295
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• 2006

PAHs (Polycyclic Aromatic Hydrocarbons), one of the carcinogenic materials in environment, were investigated in this study. The standardized analysis conditions were tested, and then various factors which affect to the ambient PAHs concentration in Seoul were estimated. Moreover, the emissions of PAHs from major stationary sources were investigated to determine the quantitative relationships between ambient PAHs concentrations and emission sources. From the factor analysis, three factors relevant to the ambient PAHs in Seoul were found. Factor 1 was related to the concentrations of chrysene, pyrene, indeno (1, 2, 3-cd)pyrene, benzo[b]fluoranthene, benzo[k]fluoranthene, and benzo prerylene which were mainly emitted from gasoline and diesel fueled cars. Factor 2 showed higher loadings in phenanthrene and anthracene which were due to LNG and BC oil combustion in industry and home. And factor 3 included dibenz(a, h)anthracene and acenaphthene which were emitted from open burning and municipal solid waste incineration. Conclusively, all of three factors were consisted in 82% of total variance. The contribution of mobile sources in ambient air in Seoul was estimated at 64%, that of industrial and home sources at 17%, and that of open burning and municipal incineration at 1%.

• Biomolecules & Therapeutics
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• 제5권1호
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• pp.23-35
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• 1997

Physiological effects in SAM P6 and Rl by administration of Cervus cornu, Astragali Radix, Rehmanniae Radix, and Angelicae Radix extracts were screened to know in vivo activities of each extracts. We measured complete blood cells (CBC) such as aBC, HGB, and HCT using coulter's method. Plasma concentrations of albumin, glucose, alkaline phosphatase, calcium, creatinine, inorganic phosphate, urea and total iron ere also analyzed using biochemical clinical autoanalyzer. Plasma concentrations of cortisol, total T$_3$, and total T$_4$ were measured by chemiluminescent immunoassay methods. At 12 weeks after birth, Cervus conu or Astragali Radix or Rehmanniae Radix extracts were given 5 g/Kg.day p.o. for 0,7,14,21, and 30 days each in both SAM Rl and SAM P6. Angelicae Radix study was done the same as the others except the mice were 16 weeks after birth. The RBC, HGB, and HCT levels after administration of Astragali and Rehmanniae were elevated in SAM Rl, but those in Cervi study were increased in SAM P6 the most. Decreases in alkaline phosphatase concentration of SAM Rl and P6 after Cervi administration were detected. Total plasma iron concentration was decreased by Angelicae administration in SAM P6. In general, Angelicae and Rehmanniae stimulate increases in cortisol, but total T$_3$ and T$_4$ levels were also elevated by all these extracts. In conclusion, these herval medicine extracts help hematopoiesis in SAMs through probably different mechanisms.

• 식물조직배양학회지
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• 제27권6호
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• pp.475-478
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• 2000

상추에 particle bombardment를 이용한 배추 Glutathione Reductase (GR)유전자의 형질전환효율 향상 및 형질전환체의 유전분석에 관한 실험을 수행하여 얻은 결과를 요약하면 다음과 같다. Particle bombardment 이용시 사출 전 4시간, 사출 후 16시간 동안 삼투조절제인 0.6M serbitolfmannitol 을 처리하여 형질전환시킨 상추 자엽조직에서 GUS 반응 spot이 가장 많았다. 0.3, 0.6, 1.5 kbp로 나타나는 3가지 종류의 primer를 사용하여 PCR한 결과 각각의 primer에 homology를 타나내는 band를 확인하여 355 promoter와 BcGRl유전자가 삽입이 된 것을 확인하였다. 형질전환된 상추의 자식 종자를 채종하여 kanamycin 200mg/L이 첨가된 MS배지에 파종하여 형질전환시키지 않은 상추의 자식 종자와 비교해 본 결과, 형질전환된 상추의 종자에서 발아된 유묘의 약 70%정도가 kanamycin에 대해 내성을 나타내었다.