• Title/Summary/Keyword: A new host

Search Result 938, Processing Time 0.028 seconds

Immunogenomics approaches to study host innate immunity against intestinal parasites

  • Lillehoj, Hyun S.
    • Proceedings of the Korea Society of Poultry Science Conference
    • /
    • 2006.11a
    • /
    • pp.7-16
    • /
    • 2006
  • Poultry products including meat and eggs constitute a major protein source in the American diet and disease - causing pathogens represent major challenges to the poultry industry. More than 95 % of pathogens enter the host through the mucosal surfaces of the respiratory, digestive and reproductive tracts and over the past few decades, the two main mechanisms used to control diseases have been the use of vaccines and antibiotics. However, in the poultry industry, there are mounting concerns over the ability of current vaccines to adequately protect against emerging hyper - virulent strains of pathogens and a lack of suitable, cost effective adjuvants. Thorough investigation of the immunogenetic responses involved in host-pathogen interactions will lead to the development of new and effective strategies for improving poultry health, food safety and the economic viability of the US poultry industry. In this paper, I describe the development of immunogenomic and proteomic tools to fundamentally determine and characterize the immunological mechanisms of the avian host to economically significant mucosal pathogens such as Eimeria. Recent completion of poultry genome sequencing and the development of several tissue-specific cDNA libraries in chickens are facilitating the rapid application of functional immunogenomics in the poultry disease research. Furthermore, research involving functional genomics, immunology and bioinformatics is providing novel insights into the processes of disease and immunity to microbial pathogens at mucosal surfaces. In this presentation, a new strategy of global gene expression using avian macrophage (AMM) to characterize the multiple pathways related to the variable immune responses of the host to Eimeria is described. This functional immunogenomics approach will increase current understanding of how mucosal immunity to infectious agents operates, and how it may be enhanced to enable the rational development of new and effective strategies against coccidiosis and other mucosal pathogens.

  • PDF

High efficiency deep blue phosphorescent organic light emitting diodes using a phenylcarbazole type phosphine oxide as a host material

  • Jeon, Soon-Ok;Yook, Kyoung-Soo;Lee, Jun-Yeob
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2009.10a
    • /
    • pp.188-191
    • /
    • 2009
  • A high efficiency deep blue phosphorescent organic light-emitting diode (PHOLED) was developed using a new wide triplet bandgap host material (PPO1) with a phenylcarbazole and a phosphine oxide unit. The wide triplet bandgap host material was synthesized by a phosphornation reaction of 2-bromo-Nphenylcarbazole with chlorodiphenylphosphine. A deep blue emitting phosphorescent dopant, tris((3,5-difluoro-4-cyanophenyl)pyridine)iridium (FCNIr), was doped into the PPO1 host and a high quantum efficiency of 17.1 % and a current efficiency of 19.5 cd/A with a color coordinate of (0.14,0.15) were achieved in the blue PHOLED. The quantum efficiency of the deep blue PHOLED was better than any other quantum efficiency value reported up to now.

  • PDF

A Review of Host Plants of Cerambycidae (Coleoptera: Chrysomeloidea) with new Host Records for Fourteen Cerambycids, Including the Asian Longhorn Beetle (Anoplophora glabripennis Motschulsky), in Korea (유리알락하늘소를 포함한 14종 하늘소의 새로운 기주식물 보고 및 한국산 하늘소과(딱정벌레목: 잎벌레상과)의 기주식물 재검토)

  • Lim, Jongok;Jung, Su-Young;Lim, Jong-Su;Jang, Jin;Kim, Kyung-Mi;Lee, You-Mi;Lee, Bong-Woo
    • Korean journal of applied entomology
    • /
    • v.53 no.2
    • /
    • pp.111-133
    • /
    • 2014
  • A revised checklist of host plants for 181 species belonging to 103 genera in six subfamilies of Cerambycidae (Coleoptera: Chrysomeloidea) in Korea is provided on the basis of the results of field surveys and literature review. A total of 14 new cerambycid-host associations are confirmed and the Manchurian striped maple, Acer tegmentosum Maxim. (Aceraceae), is listed as a new host of the Asian longhorn beetle, Anoplophora glabripennis (Motschulsky). The names of more than 170 host plants species belonging to 107 genera in 44 families are compiled. Among them, four families (Ulmaceae, Pinaceae, Fagaceae and Betulaceae) are confirmed as the main host families (more than 23%) of most of the cerambycid species. All invalid scientific names and Korean names of plants and cerambycids in the previous literature are corrected in the present paper.

Conger myriaster, a new second intermediate host of Heterophyopsis continua (Digenea: Heterophyidae) (긴이형흡충(Heterophyopsis continua)의 새로운 중간숙주인 붕장어(Conger myriaster))

  • Kim, Gi-Hong;Choe, Eun-Seok;Im, Han-Jong
    • Parasites, Hosts and Diseases
    • /
    • v.34 no.4
    • /
    • pp.283-285
    • /
    • 1996
  • Six metacercariae were found from the gill filaments of Conger myriaster purchased at Mokpo-shi in korean on September, 1996. Based on the morphology of the excysted specimen. we identified them as metacercariae of Heterophyosis continua, C. myriaster is a new intermediate host H. continua in the literature.

  • PDF

New Finding of Golovinomyces salviae Powdery Mildew on Glechoma longituba (Lamiaceae), Besides Its Original Host Salvia spp.

  • In-Young Choi;Lamiya Abasova;Joon-Ho Choi;Young-Joon Choi;Hyeon-Dong Shin
    • The Korean Journal of Mycology
    • /
    • v.51 no.3
    • /
    • pp.239-243
    • /
    • 2023
  • The Golovinomyces biocellatus complex is known to consist of powdery mildew from the Golovinomyces genus, associated with host plants from the Lamiaceae family. Recent molecular phylogenetic analyses have resolved the taxonomic composition of this complex, and Golovinomyces biocellatus sensu stricto is considered to be a pathogen of Glechoma species, globally. However, this paper presents a new finding of Golovinomyces salviae on Glechoma longituba, besides its original host species of Salvia. This information was inferred by molecular phylogenetic analyses from the multi-locus nucleotide sequence dataset of intergeneric spacer (IGS), internal transcribed spacer (ITS), large subunit (LSU) of rDNA, and glyceraldehyde-3-phosphate dehydrogenase (GAPDH) gene. Further, the asexual morphology of this fungus is described and illustrated.

New Bipolar Green Host Materials Containing Benzimidazole-Carbazole Moiety in Phosphorescent OLEDs

  • Park, Jung-Hwan;Kim, Eun-Kyung;El-Deeb, Ibrahim M.;Jung, Su-Jin;Choi, Dae-Hyuk;Kim, Dong-Ha;Yoo, Kyung-Ho;Kwon, Jang-Hyuk;Lee, So-Ha
    • Bulletin of the Korean Chemical Society
    • /
    • v.32 no.3
    • /
    • pp.841-846
    • /
    • 2011
  • New green host materials, 9-phenyl-3-(4-(1-phenyl-1H-benzo[d] imidazol-2-yl)phenyl)-9H-carbazole (3a) and 9-(naphthyl-2-yl)-3-(4-(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl)-9H-carbazole (3b), have been designed and synthesized by attaching the electron transporting benzimidazole moiety to the hole transporting carbazole unit. These compounds have similar HOMO, LUMO levels and band-gap characteristics compared with CBP (4,4'-di(N-carbazolyl)biphenyl). The fabricated green phosphorescent OLED with this 3a host shows much better device performances compared to CBP-based one. The current and power efficiency is enhanced at least by 60 percent at a given constant luminance of 1000 cd/$m^2$.

2-Undecanone derived from Pseudomonas aeruginosa modulates the neutrophil activity

  • Jeong, Yu Sun;Huh, Sunghyun;Kim, Ji Cheol;Park, Ji Ye;Lee, ChaeEun;Kim, Min-Sik;Koo, JaeHyung;Bae, Yoe-Sik
    • BMB Reports
    • /
    • v.55 no.8
    • /
    • pp.395-400
    • /
    • 2022
  • Pseudomonas aeruginosa (P. aeruginosa) is a well-known Gramnegative opportunistic pathogen. Neutrophils play key roles in mediating host defense against P. aeruginosa infection. In this study, we identified a metabolite derived from P. aeruginosa that regulates neutrophil activities. Using gas chromatography-mass spectrometry, a markedly increased level of 2-undecanone was identified in the peritoneal fluid of P. aeruginosa-infected mice. 2-Undecanone elicited the activation of neutrophils in a Gαi-phospholipase C pathway. However, 2-undecanone strongly inhibited responses to lipopolysaccharide and bactericidal activity of neutrophils against P. aeruginosa by inducing apoptosis. Our results demonstrate that 2-undecanone from P. aeruginosa limits the innate defense activity of neutrophils, suggesting that the production of inhibitory metabolites is a strategy of P. aeruginosa for escaping the host immune system.

Highly efficient deep-blue electroluminescence using doped PCVtPh with a new host material

  • Park, Jeong-Keun;Lee, Kum-Hee;Kim, Seul-Ong;Park, Jung-Sun;Seo, Ji-Hoon;Kim, Young-Kwan;Yoon, Seung-Soo
    • 한국정보디스플레이학회:학술대회논문집
    • /
    • 2009.10a
    • /
    • pp.775-778
    • /
    • 2009
  • Novel blue host material, 4,4'-(dinaphthalen-2-yl)-1,1'-binaphthyl (DNBN), was designed and synthesized for OLEDs. In order to test the electroluminescent properties of DNBN, DNBN was used as the host materials for a blue emitter, PCVtPh. The device exhibited deep-blue emission with the CIEx,y coordinates (x=0.15, y=0.08) at 8.0 V, a luminous efficiency of 1.66 cd/A, a power efficiency of 0.77 lm/W and an external quantum efficiency of 2.30 % at 20 mA/$cm^2$, respectively.

  • PDF

Relationship Between Plant Viral Encoded Suppressor to Post-transcriptional Gene Silencing and Elicitor to R Gene-specific Host Resistance

  • Park, Chang-Won;Feng Qu;Tao Ren;T. Jack Morris
    • The Plant Pathology Journal
    • /
    • v.20 no.1
    • /
    • pp.22-29
    • /
    • 2004
  • Many important horticultural and field crops are susceptible to virus infections or may possess a degree of resistance to some viruses, but become infected by others. Plant viruses enter cells through the presence of wounds, and replicate intracellularly small genomes that encode genes required for replication, cell-to-cell movement and encapsidation. There are numerous evidences from specific virus-host interactions to require the involvement of host factors and steps during viral replication cycle. However, viruses should deal with host defense responses either by general or specific mechanisms, targeting viral components or genome itself. On the other hand, the host plants have also adapted to defend themselves against viral attack by operating different lines of resistance responses. The defense-related interactions provide new insights into the complex molecular strategies for hosts for defense and counter-defense employed by viruses.

De-correlated Compression Filter Based on Time-Propagated Measurement Fusion

  • Lee, Hyung-Keun;Lee, Jang-Gyu;Jee, Gyu-In;Park, Chan-Gook
    • 제어로봇시스템학회:학술대회논문집
    • /
    • 2001.10a
    • /
    • pp.76.2-76
    • /
    • 2001
  • In this paper, a new fusion architecture consisting of a host filter and a do-correlated compression filter is proposed based on propagated measurement fusion. In the proposed architecture, the host filter estimates the system states in long-term sense based on the measurements from the beginning to the current time. The de-correlated compression filter assists the host filter by providing fusion results in short-term sense based on the measurements within a block of time. The proposed de-correlated compression filter alleviates computational burden of the host filter by reducing the maximum amount of instantaneous computation, and provides an efficient environment for real-time fault detection and estimation.

  • PDF