• Proceedings of the Korean Society of Life Science Conference
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• 2007.10a
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• pp.116.2-116.2
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• 2007

See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.104.1-104.1
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• 2007

See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2007.10a
• /
• pp.121.2-121.2
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• 2007

See Full Text

• Proceedings of the Korean Society of Crop Science Conference
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• 2001.05a
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• pp.240-241
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• 2001

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2001.05a
• /
• pp.66-67
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• 2001

• Proceedings of the Korean Society of Life Science Conference
• /
• 2000.09a
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• pp.24-24
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• 2000

• Proceedings of the Zoological Society Korea Conference
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• 1999.10b
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• pp.291.2-291
• /
• 1999

No Abstract, See Full Text

• Proceedings of the Korean Society of Life Science Conference
• /
• 2006.09a
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• pp.34.1-34.1
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• 2006

• Proceedings of the Korean Society of Life Science Conference
• /
• 2006.09a
• /
• pp.34.2-34.2
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• 2006

• Archives of Pharmacal Research
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• v.28 no.4
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• pp.400-404
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• 2005

Activity-guided fractionation of a hexane-soluble extract of the roots of Lithospermum erythrorhizon, using a mouse brain monoamine oxidase (MAO) inhibition assay, led to the isolation of two known naphthoquinones, acetylshikonin and shikonin, and a furylhydroquinone, shikonofuran E. These compounds were shown to inhibit MAO with $IC_{50}$ values of 10.0, 13.3, and $59.1 {\mu}M$, respectively. Although no specificity for MAO-A and MAO-B was shown by acetylshikonin and shikonin, a Lineweaver-Burk plot analysis indicated that the inhibition was competitive for both MAO-A and MAO-B activity.