• 제목/요약/키워드: 6LiF

검색결과 408건 처리시간 0.026초

An Ester Extract of Cochinchina Momordica Seeds Induces Differentiation of Melanoma B16 F1 Cells via MAPKs Signaling

  • Zhao, Lian-Mei;Han, Li-Na;Ren, Feng-Zhi;Chen, Shu-Hong;Liu, Li-Hua;Wang, Ming-Xia;Sang, Mei-Xiang;Shan, Bao-En
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권8호
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    • pp.3795-3802
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    • 2012
  • Cochinchina momordica seeds (CMS) have been widely used due to antitumor activity by Mongolian tribes of China. However, the details of the underlying mechanisms remain unknown. In the present study, we found that an EtOAc (ethyl ester) extract of CMS (CMSEE) induced differentiation and caused growth inhibition of melanoma B16 F1 cells. CMSEE at the concentration of $5-200{\mu}g/ml$ exhibited strongest anti-proliferative effects on B16 F1 cells among other CMS fractions (water or petroleum ether). Moreover, CMSEE induced melanoma B16 F1 cell differentiation, characterized by dendrite-like outgrowth, increasing melanogenesis production, as well as enhancing tyrosinase activity. Western blot analysis showed that sustained phosphorylation of p38 MAP accompanied by decrease in ERK1/2 and JNK dephosphorylation were involved in CMSEE-induced B16 F1 cell differentiation. Notably, 6 compounds that were isolated and identified may be responsible for inducing differentiation of CMSEE. These results indicated that CMSEE contributes to the differentiation of B16 F1 cells through modulating MAPKs activity, which may throw some light on the development of potentially therapeutic strategies for melanoma treatment.

유기전해액에서 루테늄산화물 전극의 전기화학적 특성 (Electrochemical Characteristics of Ruthenium Oxide Electrode-Organic Electrolyte System)

  • 도칠훈;진봉수;문성인;윤문수;최상진;육경창;박정식;김상길;이주원
    • 전기화학회지
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    • 제6권3호
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    • pp.169-173
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    • 2003
  • 금속산화물 전극을 이용한 전기화학 캐패시터는 일반적으로 산성 수용액 전해질에서 금속산화물에 대한 양성자의 가역적인 전기화학반응을 이용한다. 수계 전해질을. 사용한 수퍼캐패시터는 전위창(electrochemical stability window)이 유기계 전해질을 사용한 수퍼캐패시터에 비해 좁은 문제를 안고 있다. 금속산화물 전극과 리튬 또는 암모늄 이온을 함유한 유기계 전해질을 사용한 전기화학 캐패시터의 특성을 확인하였다. $RuO_2$ 전극을 사용한 전기화학 캐패시터는 1M $LiPF_6$, EC, DEC 및 EMC혼합용매 전해액 중에서 순환전위전류법(주사속도. 2mV/sec, 전위영역: $2.0\~4.2V(Li|Li^+))$으로 산화 및 환원에 대하여 비정전용량을 구한 바, 각각 145 및 $142F/g-RuO_2{\cdot}nH_2O$이었다

리튬 루테튬 보레이트 섬광단결정의 잔광 특성 (Afterglow Properties of LLBO Scintillation Crystal)

  • 김성환
    • 센서학회지
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    • 제23권6호
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    • pp.416-419
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    • 2014
  • We grew a $Li_6Lu(BO_3)_3:Ce^{3+}$ single crystal as a new scintillator. And, the scintillation and thermoluminescence properties of the scintillator were determined. The emission spectrum of $Li_6Lu(BO_3)_3:Ce^{3+}$ is located in the range of 370~530 nm, peaking at 416 nm and 439 nm, due to the $5d{\rightarrow}4f$ transition of $Ce^{3+}$ ions. The fluorescence decay time of the crystal is composed two components. The fast component is 34 ns (84%) and the slow component is 125 ns (16%) of the crystal. The afterglow is caused by the electron and hole traps in the crystal lattice. We determined physical parameters of the traps in the crystal. The thermoluminescence trap are composed a trap. The determined activation energy (E) and frequency factor (s) of the TL trap are 1.05 eV and $4.4{\times}10^{10}s^{-1}$, respectively.

한국산 참복속 어류 1 미기록종 Fugu flavidus (First Record of Fugu flavidus, from Korea)

  • 김익수;이완옥
    • 한국어류학회지
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    • 제1권1_2호
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    • pp.19-23
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    • 1989
  • 1985년 2월부터 1989년 6월까지 전북 군산과 전남 목포 연안에서 수집된 참복과 어류 가운데 체장 101.5-258.2 mm의 8 개체는 우리나라에서 알려지지 않은 Fugu flavidus Li, Wang et Wang으로 동정되었다. 본 종의 어린 개체는 황갈색 바탕에 흰반점이 산재하나 성체에 가까울수록 흰반점은 희미해지며, 완전한 성체가 되면 몸 전체가 황갈색을 띤다. 모든 개체는 입에서 꼬리지느러미 기부에 까지 황색띠가 뚜렷한 점 등 유연종인 복섬 Fugu niphobles과 잘 구분되고, 또 어릴 때와 성체에서 반문의 차이가 뚜렷하여 황복 Fugu obscurus과도 잘 구분되어 채집된 표본의 계수 계측치와 형태적 특징을 기재하고, 국명으로는 "황점복"으로 명명한다.

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Nitrogen-corrected True Metabolizable Energy and Amino Acid Digestibility of Chinese Corn Distillers Dried Grains with Solubles in Adult Cecectomized Roosters

  • Li, F.;Liu, Y.;Yin, R.Q.;Yang, X.J.;Yao, J.H.;Sun, F.F.;Li, G.J.;Liu, Y.R.;Sun, Y.J.
    • Asian-Australasian Journal of Animal Sciences
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    • 제26권6호
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    • pp.838-844
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    • 2013
  • This study was conducted to evaluate chemical composition, nitrogen-corrected true metabolizable energy (TMEn) and true amino acids digestibility of corn distillers dried grains with solubles (DDGS) produced in China. Twenty five sources of corn DDGS was collected from 8 provinces of China. A precision-fed rooster assay was used to determine TMEn and amino acids digestibility with 35 adult cecectomized roosters, in which each DDGS sample was tube fed (30 g). The average content of ash, crude protein, total amino acid, ether extract, crude fiber and neutral detergent fiber were 4.81, 27.91, 22.51, 15.22, 6.35 and 37.58%, respectively. TMEn of DDGS ranged from 1,779 to 3,071 kcal/kg and averaged 2,517 kcal/kg. Coefficient of variation for non-amino acid crude protein, ether extract, crude fiber and TMEn were 55.0, 15.7, 15.9 and 17.1%, respectively. The average true amino acid digestibility was 77.32%. Stepwise regression analysis obtained the following equation: TMEn, kcal/kg = -2,995.6+0.88${\times}$gross energy+$49.63{\times}a^*$ (BIC = 248.8; RMSE = 190.8; p<0.01). Removing gross energy from the model obtained the following equation: TMEn, kcal/kg = 57.88${\times}$ether extracts+$87.62{\times}a^*$ (BIC = 254.3, RMSE = 223.5; p<0.01). No correlation was found between color scores and lysine true digestibility (p>0.05). These results suggest that corn DDGS produced in China has a large variation in chemical composition, and gross energy and $a^*$ value can be used to generate TMEn predict equation.

6 MV X-선 조사시 중두개와에서의 선량감쇠 (Dose Attenuation in the Mid-Cranial Fossa with 6 MV Photon Beam Irradiations)

  • 박정호;최태진;김옥배
    • Radiation Oncology Journal
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    • 제8권1호
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    • pp.125-131
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    • 1990
  • 방사선조사시 선량분포에 영향을 미치는 여러가지 요소들 중에서 조직불균등성은 선량을 상당히 변화시킨다. 특히, 중뇌강은 여러골조직으로 구성되어 있어 조직 불균등성에 따른 상당한 선랑감쇠가 예상된다. 6 MV X-선 조사후 중두개와에서의 선량분포측정은 LiF TLD 소자를 이용하였으며 같은 측정장소에서, 계산에 의한 예상선량과 실측선량의 비교를 시도하였다. 계산에 의하면, 골조직 1 cm당 예상선량감쇠는 $3.74\%$를 나타내었다. 한편, 골조직을 고려한 예상선량과 실측선량의 차이는 매우 적었으며 $\pm0.21\%$의 오차범위내에서 일치됨을 나타내었다.

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1채널 단일광자검출기를 이용한 낮은 광출력의 SWIR(Short Wave Infrared) 3D 라이다 시스템 개발 (Development of SWIR 3D Lidar System with Low Optical Power Using 1 Channel Single Photon Detector)

  • 권오성;이승필;신승민;박민영;반창우
    • 한국산업융합학회 논문집
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    • 제25권6_3호
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    • pp.1147-1154
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    • 2022
  • Now that the development of autonomous driving is progressing, LiDAR has become an indispensable element. However, LiDAR is a device that uses lasers, and laser side effects may occur. One of them is the much-talked-about eye-safety, and developers have been satisfying this through laser characteristics and operation methods. But eye-safety is just one of the problems lasers pose. For example, irradiating a laser with a specific energy level or higher in a dusty environment can cause deterioration of the dust particles, leading to a sudden explosion. For this reason, the dust ignition proof regulations clearly state that "a source with a pulse period of less than 5 seconds is considered a continuous light source, and the average energy does not exceed 5 mJ/mm 2 or 35 mW" [2]. Energy of output optical power is limited by the law. In this way, the manufacturer cannot define the usage environment of the LiDAR, and the development of a LiDAR that can be used in such an environment can increase the ripple effect in terms of use in application fields using the LiDAR. In this paper, we develop a LiDAR with low optical power that can be used in environments where high power lasers can cause problems, evaluate its performance. Also, we discuss and present one of the directions for the development of LiDAR with laser power limited by dust ignition proof regulations.

리튬 2차전지용 양극소재 $LiFePO_4/C$의 합성 및 리트벨트 구조분석 (Synthesis and Rietveld Refinement of the Cathode Material $LiFePO_4/C$ for Rechargeable Lithium Batteries)

  • 황길찬;최진범;김재광;안주현
    • 한국광물학회지
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    • 제22권1호
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    • pp.63-72
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    • 2009
  • 개량된 MA법으로 합성된 $LiFe(PO_4)/C$에 대해 X-선 회절분석을 실시하여 리트벨트법에 의해 결정학적 연구를 수행하였다. 리트벨트 계산 결과 리트벨트 R 지수 값은 $R_p=8.14%,\;R_{wp}=11.1%,\;R_{exp}=9.09%,\;R_B=3.88%$, S (GofF, Goodness of fit) = 1.2으로 계산이 잘 이루어졌음을 알 수 있다. $LiFePO_4/C$는 공간군 Pnma를 가지며, 격자상수 값은 a = 10.3229(3)${\AA}$, b = 6.0052(2) ${\AA}$, c = 4.6939(1) ${\AA}$이고 체적값은 V = 290.98(1) ${\AA}^3$으로 기존 다른 합성법의 연구결과와 잘 일치한다. 분말 입자는 고순도를 가지고 나노 크기($65{\sim}90nm$)로 기존 MA법보다 상대적으로 미세하고 균질도가 향상되었다. 따라서 개량된 MA법은 상업용 리튬 2차 전지의 양극물질 생산을 위한 우수한 제조법으로 판단된다.