• Title/Summary/Keyword: 6LiF

Search Result 408, Processing Time 0.028 seconds

An Ester Extract of Cochinchina Momordica Seeds Induces Differentiation of Melanoma B16 F1 Cells via MAPKs Signaling

  • Zhao, Lian-Mei;Han, Li-Na;Ren, Feng-Zhi;Chen, Shu-Hong;Liu, Li-Hua;Wang, Ming-Xia;Sang, Mei-Xiang;Shan, Bao-En
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.13 no.8
    • /
    • pp.3795-3802
    • /
    • 2012
  • Cochinchina momordica seeds (CMS) have been widely used due to antitumor activity by Mongolian tribes of China. However, the details of the underlying mechanisms remain unknown. In the present study, we found that an EtOAc (ethyl ester) extract of CMS (CMSEE) induced differentiation and caused growth inhibition of melanoma B16 F1 cells. CMSEE at the concentration of $5-200{\mu}g/ml$ exhibited strongest anti-proliferative effects on B16 F1 cells among other CMS fractions (water or petroleum ether). Moreover, CMSEE induced melanoma B16 F1 cell differentiation, characterized by dendrite-like outgrowth, increasing melanogenesis production, as well as enhancing tyrosinase activity. Western blot analysis showed that sustained phosphorylation of p38 MAP accompanied by decrease in ERK1/2 and JNK dephosphorylation were involved in CMSEE-induced B16 F1 cell differentiation. Notably, 6 compounds that were isolated and identified may be responsible for inducing differentiation of CMSEE. These results indicated that CMSEE contributes to the differentiation of B16 F1 cells through modulating MAPKs activity, which may throw some light on the development of potentially therapeutic strategies for melanoma treatment.

Electrochemical Characteristics of Ruthenium Oxide Electrode-Organic Electrolyte System (유기전해액에서 루테늄산화물 전극의 전기화학적 특성)

  • Doh, Chil-Hoon;Jin, Bong-Soo;Moon, Seong-In;Yun, Mun-Soo;Choi, Sang-Jin;Yug, Gyeong-Chang;Park, Jeong-Sik;Kim, Sang-Gil;Lee, Joo-Won
    • Journal of the Korean Electrochemical Society
    • /
    • v.6 no.3
    • /
    • pp.169-173
    • /
    • 2003
  • Electrochemical capacitor made with metal oxide electrode uses rapid and reversible protonation/deprotonation of metal oxide material under the aqueous acidic solution, generally. Electrochemical stability window of aqueous electrolyte-type capacitor is narrow compared to that of organic electrolyte-type capacitor. Electrochemical characteristics of electrochemical capacitor made with metal oxide electrode and lithium or ammonium cation based organic electrolyte were evaluated. Electrochemical capacitor based on $RuO_2$ electrode material and 1M $LiPF_6$ in mixed solvents of EC, DEC, and EMC has anodic and cathodic specific capacitance of 145 and $142F/g-RuO_2{\cdot}nH_2O$, respectively, by using cyclic voltammetry with scan rate of 2mV/sec $g-RuO_2$ in potential range of $2.0\~4.2V(Li|Li^+))$.

Afterglow Properties of LLBO Scintillation Crystal (리튬 루테튬 보레이트 섬광단결정의 잔광 특성)

  • Kim, Sunghwan
    • Journal of Sensor Science and Technology
    • /
    • v.23 no.6
    • /
    • pp.416-419
    • /
    • 2014
  • We grew a $Li_6Lu(BO_3)_3:Ce^{3+}$ single crystal as a new scintillator. And, the scintillation and thermoluminescence properties of the scintillator were determined. The emission spectrum of $Li_6Lu(BO_3)_3:Ce^{3+}$ is located in the range of 370~530 nm, peaking at 416 nm and 439 nm, due to the $5d{\rightarrow}4f$ transition of $Ce^{3+}$ ions. The fluorescence decay time of the crystal is composed two components. The fast component is 34 ns (84%) and the slow component is 125 ns (16%) of the crystal. The afterglow is caused by the electron and hole traps in the crystal lattice. We determined physical parameters of the traps in the crystal. The thermoluminescence trap are composed a trap. The determined activation energy (E) and frequency factor (s) of the TL trap are 1.05 eV and $4.4{\times}10^{10}s^{-1}$, respectively.

First Record of Fugu flavidus, from Korea (한국산 참복속 어류 1 미기록종 Fugu flavidus)

  • Kim, Ik-Soo;Lee, Wan-Ok
    • Korean Journal of Ichthyology
    • /
    • v.1 no.1_2
    • /
    • pp.19-23
    • /
    • 1989
  • A puffer fish Fugu flavidus Li, Wang et Wang of Family Tetraodontidae was studied for the first time in Korea. Specimens were obtained from fish markets in Kunsan and Mokpo in February 1985 and June 1989. The Fugu flavidus is similar to F. obscurus and F. niphobles in morphometric characters, but differs from them in dorsal part of the body : yellowish-brown or greenish-brown, and covered with many round white spots which are clear in young and become indistinct as the fish grow. A new Korean name "Hwangjombok" is proposed for the F. flavidus.

  • PDF

Nitrogen-corrected True Metabolizable Energy and Amino Acid Digestibility of Chinese Corn Distillers Dried Grains with Solubles in Adult Cecectomized Roosters

  • Li, F.;Liu, Y.;Yin, R.Q.;Yang, X.J.;Yao, J.H.;Sun, F.F.;Li, G.J.;Liu, Y.R.;Sun, Y.J.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.26 no.6
    • /
    • pp.838-844
    • /
    • 2013
  • This study was conducted to evaluate chemical composition, nitrogen-corrected true metabolizable energy (TMEn) and true amino acids digestibility of corn distillers dried grains with solubles (DDGS) produced in China. Twenty five sources of corn DDGS was collected from 8 provinces of China. A precision-fed rooster assay was used to determine TMEn and amino acids digestibility with 35 adult cecectomized roosters, in which each DDGS sample was tube fed (30 g). The average content of ash, crude protein, total amino acid, ether extract, crude fiber and neutral detergent fiber were 4.81, 27.91, 22.51, 15.22, 6.35 and 37.58%, respectively. TMEn of DDGS ranged from 1,779 to 3,071 kcal/kg and averaged 2,517 kcal/kg. Coefficient of variation for non-amino acid crude protein, ether extract, crude fiber and TMEn were 55.0, 15.7, 15.9 and 17.1%, respectively. The average true amino acid digestibility was 77.32%. Stepwise regression analysis obtained the following equation: TMEn, kcal/kg = -2,995.6+0.88${\times}$gross energy+$49.63{\times}a^*$ (BIC = 248.8; RMSE = 190.8; p<0.01). Removing gross energy from the model obtained the following equation: TMEn, kcal/kg = 57.88${\times}$ether extracts+$87.62{\times}a^*$ (BIC = 254.3, RMSE = 223.5; p<0.01). No correlation was found between color scores and lysine true digestibility (p>0.05). These results suggest that corn DDGS produced in China has a large variation in chemical composition, and gross energy and $a^*$ value can be used to generate TMEn predict equation.

Dose Attenuation in the Mid-Cranial Fossa with 6 MV Photon Beam Irradiations (6 MV X-선 조사시 중두개와에서의 선량감쇠)

  • Park, Jeong-Ho;Choi, Tae-Jin;Kim, Ok-Bae
    • Radiation Oncology Journal
    • /
    • v.8 no.1
    • /
    • pp.125-131
    • /
    • 1990
  • In X-ray irradiation, dose distribution depends on multiple parameters, one of them being tissue inhomogeneity to change the dose significantly. considerable dose attenuation through the mid-cranial fossa is expected because of various bony structures in it. Dose distribution around the mid-cranial fossa, following irradiation with 6 MV photon beam, was measured with LiF TLD micro-rod, and compared with the expected dose inthe same sites. In our calculation with $C_f$(correction factor), the expected dose attenuation revealed about $3.74\%$ per 1 cm thickness of bone tissue. And the differences between the expected dose with correction for bone tissue and the measured dose by TLD was small, agreeing within an average variation of $\pm0.21\%$.

  • PDF

Development of SWIR 3D Lidar System with Low Optical Power Using 1 Channel Single Photon Detector (1채널 단일광자검출기를 이용한 낮은 광출력의 SWIR(Short Wave Infrared) 3D 라이다 시스템 개발)

  • Kwon, Oh-Soung;Lee, Seung-Pil;Shin, Seung-Min;Park, Min-Young;Ban, Chang-Woo
    • Journal of the Korean Society of Industry Convergence
    • /
    • v.25 no.6_3
    • /
    • pp.1147-1154
    • /
    • 2022
  • Now that the development of autonomous driving is progressing, LiDAR has become an indispensable element. However, LiDAR is a device that uses lasers, and laser side effects may occur. One of them is the much-talked-about eye-safety, and developers have been satisfying this through laser characteristics and operation methods. But eye-safety is just one of the problems lasers pose. For example, irradiating a laser with a specific energy level or higher in a dusty environment can cause deterioration of the dust particles, leading to a sudden explosion. For this reason, the dust ignition proof regulations clearly state that "a source with a pulse period of less than 5 seconds is considered a continuous light source, and the average energy does not exceed 5 mJ/mm 2 or 35 mW" [2]. Energy of output optical power is limited by the law. In this way, the manufacturer cannot define the usage environment of the LiDAR, and the development of a LiDAR that can be used in such an environment can increase the ripple effect in terms of use in application fields using the LiDAR. In this paper, we develop a LiDAR with low optical power that can be used in environments where high power lasers can cause problems, evaluate its performance. Also, we discuss and present one of the directions for the development of LiDAR with laser power limited by dust ignition proof regulations.

Synthesis and Rietveld Refinement of the Cathode Material $LiFePO_4/C$ for Rechargeable Lithium Batteries (리튬 2차전지용 양극소재 $LiFePO_4/C$의 합성 및 리트벨트 구조분석)

  • Hwang, Gil-Chan;Choi, Jin-Beom;Kim, Jae-Kwang;Ahn, Jou-Hyeon
    • Journal of the Mineralogical Society of Korea
    • /
    • v.22 no.1
    • /
    • pp.63-72
    • /
    • 2009
  • Carbon-coated lithium iron phosphate ($LiFePO_4/C$) composites are synthesized by the modified mechanical activation method (modified MA process) and studied by the Rietveld structural refinement. Rietveld indices of $LiFePO_4/C$ indicate good fitting with $R_p=8.14%,\;R_{wp}=11.1%,\;R_{exp}=9.09%,\;R_B=3.88%$, and S (GofF, Goodness of fit) = 1.2, respectively. $LiFePO_4/C$ with a space group Pnma shows a = 10.3229(3)${\AA}$, b = 6.0052(2) ${\AA}$, c = 4.6939(1) ${\AA}$, and V = 290.98(1) ${\AA}^3$ in dimension, indicating good agreements with those of previous works. Synthetic powders are nano-sized ($65{\sim}90nm$) homogeneous particles with high purity. Thus the modified MA method will be an efficient process to get a high quality cathode material for commercial lithium batteries.