• Development and Reproduction
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• v.16 no.2
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• pp.87-93
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• 2012

Reproductive biology (maturation and spawning) of the female tongue sole Cynoglssus semilaevis were examined in 154 specimens caught from the west coast of Korea (between February and November 2010). Monthly changes of gonadosomatic index (GSI) and condition factor (CF) were peaked in September. Hepatosomatic index (HSI) showed a negative correlation with those of the GSI. Ovaries were classified into six stages based on the development of advanced oocyte and histological characteristics: virgin/immature, early developing, developing, late developing, ripe/spawning and spent/regressing stage. The relationship between fecundity (F) and total length (TL) of the fish was expressed as $F=251.43TL^{0.1264}$, and body weight (BW) was expressed as F=1130.4BW-880848. Biological minimum size of female was 46.87 cm (TL).

• Journal of Periodontal and Implant Science
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• v.31 no.4
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• pp.661-668
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• 2001

Anti-P. gingivalis immune sera were obtained from mice immunized with either P. gingivalis alone, or F. nucleaturm followed by P. gingivalis. Two groups of immune sera were examined for binding capacity to P. gingivalis biofilm by confocal laser scanning microscope, Antibody avidity index was also determined for each immune sera. The results indicated that prior immunization of mice with F. nucleaturm impaired P. gingivalis-specific immune sera in binding capacity to biofilm and antibody avidity to P. gingivalis. Elevated antibody responses in patients with destructive periodontal disease has often been related to suboptimal level of protective antibody $(opsonophagocytosis)^{1-3)}$ while post-immune sera obtained with experimental animals using a single periodontal pathogen demonstrated satisfactory levels of protective function against the homologous bacterial $challenge^{4,5)}$.The reason is unclear why elevated IgG responses in periodontal patients to periodontal pathogens do not necessarily reflect their protective function. Such an immune deviation might be derived from the fact that destructive periodontal disease is cumulative result of immunopathologic processes responding to an array of different colonizing microorganisms sequentially infecting in the subgingival environmental niche. Fusobacterium nucleaturm is one of the key pathogens in gingivitis, in the transitional phase of conversion of gingivitis into destructive periodontitk, and in adult $periodontitis^{6-8)}$. It also plays a central role in coaggregation with other important microbial species in subgingival $area^{6,9,10)}$ as well as in $biofilm^{11)}$, especially with Porphyromonas gingjvalis in synergism of virulence in human periodontal disease or in animal $models^{12-14)}$. This organism has also been reported to have immune modulating activity for secondary immune response to Actinobacillus $actinomycetemcomitans^{15)}$. It is presumed that sequential colonization and intermicrobial coaggregation between intermediate and late colonizers could potentially modulate the immune responses and development of specific T cell phenotypes in periodontal lesions. We have recently demonstrated the skewed polarization of P. gingivalis-specific helper T cell clones in mice immunized with F. nucleaturm followed by P. $gingivalis.^{16)}$. Consequently F. nucleaturm may initially prime the immune cells and modify their responses to the successive organism, P. gingivalis. This could explain why one frequently observes non-protective serum antibodies to P. gingivalis in periodontal patients in contrast with those obtained from animals that were immunized with $P.gingivalis\;alone^{17)}$. The present study was performed to investigate the immune modulating effect of F. nucleatum on serum binding to experimental biofilms and the avidity of anti-P. gingivalis antibody.

• Journal of Life Science
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• v.25 no.3
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• pp.323-328
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• 2015

The study of microbial diversity and richness in soil samples from a volcanic island named Ulleungdo, located east of South Korea. The soil bacterial communities on the Ulleungdo were analyzed using pyrosequencing method based on 16S rRNA gene. There were 1,613 operational taxonomic units (OUT) form soil sample. From results of a BLASTN search against the EzTaxon-e database, the validated reads (obtained after sequence preprocessing) were almost all classified at the phylum level. Proteobacteria was the most dominant phylum with 48.28%, followed by acidobacteria (26.30%), actionbacteria (6.89%), Chloroflexi (4.58), Planctomycetes (4.56%), Nitrospirae (1.83%), Bacteroidetes (1.51%), Verrucomicrobia (1.48%), and Gemmatimonadetes (1.11%). α-proteobacteria was the most dominant class with 36.07% followed by Acidobacteria_c (10.65%), Solibacteres (10.64%), δ-proteobacteria (4.42%), γ-proteobacteria (4.29%), Planctomycetacia (4.16%), Actinobacteria_c (4.00%), Betaproteobacteria (3.50%), EU686603_c (2.97%), Ktedonobacteria (2.91%), Acidimicrobiia (1.32%), Verrucomicrobiae (1.27%), Gemmatimonadetes_c (1.11%), Sphingobacteria (1.09%), and GU444092_c (1.06%). Bradyrhizobiaceae was the most dominant family with 22.83% followed by Acidobacteriaceae (10.62%), EU445199_f (5.72%), Planctomycetaceae (4.03%), Solibacteraceae (3.63%), FM209092_f (3.58%), Steroidobacter_f (2.81%), EU686603_f (2.73%), Hyphomicrobiaceae (2.33%), Ktedonobacteraceae (1.75%), AF498716_f (1.46%), Rhizomicrobium_f (1.03%), and Mycobacteriaceae (1.01%). Differences in the diversity of bacterial communities have more to do with geography than the impact on environmental factors and also the type of vegetation seems to affect the diversity of bacterial communities.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.100-111
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• 2019

This study was undertaken to recommend a dementia education program for college students, and to understand the outcome on knowledge and attitude towards dementia, awareness of aged support, and cognitive-affective empathy. Totally, 40 college students in C city, K do, were enrolled for the study, and divided into two groups of 20 each: experimental group and control group. The experimental group subjects were provided a 12-hour dementia education program; effectiveness of this program has been verified in later studies. Data were collected from November 5, 2018 to December 7, 2018; collection was before, after, and 4 weeks after the program was provided to the experimental group. Control group data were also collected in the same time frame. Data analysis was done using IBM SPSS WIN/21.0, and the percentage, mean and standard deviation were analyzed using Shapiro-Wilks test, $x^2$-test, Fisher's exact probability test, Independent t-test, Friedman test, Mann-Whitney U and Repeated Measure ANOVA. Knowledge of dementia (F=19.80, p<0.001), attitude toward dementia (z=-4.10, p<0.001), and awareness of aged support (F=6.26, p=0.017) had a significant interaction between group and time; however, cognitive-affective empathy showed no correlation (F=1.32, p<0.256). We therefore suggest strengthening the contents of future education program for dementia, developing a customized program for cognitive-affective empathy by considering subject characteristics, and further research verifying the effectiveness of the program.

• Radiation Oncology Journal
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• v.30 no.4
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• pp.173-181
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• 2012

Purpose: To evaluate the prognostic value of preoperative neck lymph node (LN) assessment with $^{18}F$-fluorodeoxyglucose positron emission tomography ($^{18}F$-FDG PET), computed tomography (CT), and magnetic resonance imaging (MRI) in oral cavity squamous cell carcinoma (OSCC) patients with pathologically positive LN. Materials and Methods: In total, 47 OSCC patients with pathologically positive LN were retrospectively reviewed with preoperative $^{18}F$-FDG PET and CT/MRI. All patients underwent surgical resection, neck dissection and postoperative adjuvant radiotherapy and/or chemotherapy between March 2002 and October 2010. Histologic correlation was performed for findings of $^{18}F$-FDG PET and CT/MRI. Results: Thirty-six (76.6%) of 47 cases were correctly diagnosed with neck LN metastasis by $^{18}F$-FDG PET and 32 (68.1%) of 47 cases were correctly diagnosed by CT/MRI. Follow-up ranged from 20 to 114 months (median, 56 months). Clinically negative nodal status evaluated by $^{18}F$-FDG PET or CT/MRI revealed a trend toward better clinical outcomes in terms of overall survival, disease-free survival, local recurrence-free survival, regional nodal recurrence-free survival, and distant metastasis-free survival rates even though the trends were not statistically significant. However, there was no impact of neck node standardized uptake value ($SUV_{max}$) on clinical outcomes. Notably, $SUV_{max}$ showed significant correlation with tumor size in LN (p < 0.01, $R^2$ = 0.62). PET and CT/MRI status of LN also had significant correlation with the size of intranodal tumor deposit (p < 0.05, $R^2$ = 0.37 and p < 0.01, $R^2$ = 0.48, respectively). Conclusion: $^{18}F$-FDG PET and CT/MRI at the neck LNs might improve risk stratification in OSCC patients with pathologically positive neck LN in this study, even without significant prognostic value of $SUV_{max}$.

• Journal of Microbiology and Biotechnology
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• v.12 no.6
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• pp.993-997
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• 2002

A glucanhydrolase (a DXAMase exhibiting both dextranolytic and amylolytic activities) from Lipomyces starkeyi KSM 22 hydrolyzed polysaccharides having ${\alpha}-(1{\rightarrow}3)-,\;{\alpha}(1{\rightarrow}4)-,\;and\;{\alpha}-(1{\rightarrow}6)$-D-glucosidic linkages. The oral hygiene benefits of DXAMase-containing mouthwash were examined in relation to human experimental gingivitis during a 3-week period without brushing. The DXAMase-treated group exhibited a lower increase in plaque accumulation and gingival index score than the chlorhexidine-treated group. The DXAMase-treated group also showed less tongue accumulation, bad taste, and tooth staining, thus indicating a positive role for DXAMase as an antiplaque agent ingredient.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2017.11a
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• pp.3-5
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• 2017

가상 현실 시장은 꾸준한 성장을 하고 있다. 가상 현실 시장이 성장함에 따라 게임 엔진을 이용한 가상 현실콘텐츠 뿐만 아니라 실제 특수 디바이스를 이용하여 촬영한 $360^{\circ}$ 비디오 콘텐츠 시장도 성장하고 있다. 하지만 실제로 촬영한 $360^{\circ}$ 비디오같은 경우 4D 가상 현실 콘텐츠를 즐기기 위해서는 먼저 특수 장치와 $360^{\circ}$ 비디오 간의 이벤트를 정의해야 하는 성가심이 있다. 이러한 불편함을 극복하기 위해 물리적 감각 효과를 일으키는 객체를 인식하고 서술하는 기법을 제시한다. $360^{\circ}$비디오 내의 감각 효과를 일으키는 객체를 인식하고 좌표계 내에 위치를 설정하여 사용자와의 거리가 임계값 이하면 효과를 일으키게 하여 사전에 콘텐츠를 확인하고 감각 효과를 미리 설정하는 번거로움을 없앨 수 있다.

• Journal of Power Electronics
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• v.11 no.6
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• pp.897-903
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• 2011

Many voltage sag compensators have been introduced, including the traditional dynamic voltage restorer (DVR), which requires an energy storage device but is inadequate for compensating deep and long-duration voltage sags. The AC-AC sag compensators introduced next do not require a storage device and they are capable of compensating voltage sags. This type of compensator needs an AC-AC converter to regulate the output voltage. Presented in this paper is a three-phase PWM-switched autotransformer voltage sag compensator based on an AC-AC converter that uses a proposed detection technique and PWM voltage control as a controller. Its effectiveness and capability in instantly detecting and compensating voltage sags were verified via MATLAB/Simulink simulations and further investigated through a laboratory prototype developed with a TMS320F2812 DSP as the main controller.

• Bulletin of the Korean Chemical Society
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• v.26 no.6
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• pp.959-965
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• 2005

Investigation of structure-activity relationships of novel quinazolines has identified 7,8-dihydro-[1,4]dioxino-[2,3-g]quinazolines as a potent inhibitor of EGFR. These compounds have a benzodioxane framwork, which was prepared by regioselective O-alkylation of ethyl 3,4-dihydroxy benzoate by epoxide ring opening. Compounds 3f and 3k were more potent than ZD-1839 in EGF enzyme and EGFR autophosporylation inhibition assays.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.06a
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• pp.239-241
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• 2022

MIV(MPEG Immersive Video) 표준은 제한된 3D 공간의 다양한 위치의 뷰(view)들을 효율적으로 압축하여 사용자에게 임의의 위치 및 방향에 대한 6 자유도(6DoF)의 몰입감을 제공한다. MIV 의 참조 소프트웨어인 TMIV(Test Model for Immersive Video)에서는 몰입감을 제공하기 위한 여러 시점의 입력 뷰들 간의 중복 영역을 제거하고 남은 영역들을 패치(patch)로 만들어 패킹(packing)한 아틀라스(atlas)를 생성하고 이를 압축 전송한다. 아틀라스 영상은 일반적인 영상 달리 많은 불연속성을 포함하고 있으며 이는 부호화 효율을 크게 저하시키다 본 논문에서는 아틀라스 영상의 부호화 손실을 줄이기 위한 신경망 기반의 후처리 필터링 기법을 제시한다. 제안기법은 기존의 TMIV 와 비교하여 아틀라스의 복원 화질 향상을 보여준다.