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Comparison of Tc-99m DISIDA Hepatobiliary Scintigraphy and Percutaneous Needle Biopsy in the Differential Diagnosis of Biliary Atresia and Intrahepatic Cholestasis (영아 담도폐쇄증 진단에서 Tc-99m DISIDA 간담도주사와 경피간침생검의 의의)

  • Kim, Woo-Suk;Park, Woo-Hyun;Choi, Soon-Ok;Kim, Sang-Pyo
    • Advances in pediatric surgery
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    • v.3 no.1
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    • pp.6-14
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    • 1997
  • To differentiate biliary atresia from intraheaptic cholestasis, Tc-99m DlSIDA hepatobiliary scintigraphies and percutaneous needle biopsies of 60 consecutive infants were evaluated retrospectively. Twenty three patients had biliary atresia and 37 patients intraheaptic cholestasis(neonatal hepatitis 34, TPN induced jaundice 2 and Dubin-Johnson syndrome 1). All sixty patients underwent Tc-99m DlSIDA hepatobiliary scintigraphy with phenobarbital pretreatment. Of 23 patients with biliary atresia, 22 were correctly interpreted showing 96% sensitivity while of 37 patients with intraheaptic cholestasis, only 12 had intestinal excretion of radionuclide showing 32% specificity. Among the forty needle biopsies, 17 of biliary atresia and 23 of intrahepatic cholestasis, 37 were correctly interpreted as either having biliary atresia or intrahepatic cholestasis. The overall diagnostic accuracy was 93%. Of 3 misdiagnosed cases, the histologic findings of two patients with biliary atresia(aged 43 days and 54 days at the first needle biopsy) were essentially the same as those of neonatal hepatitis. Follow-up biopsies, however, showed findings consistent with biliary atresia. The third one(VLBW premie with history of 8 weeks of TPN) showed mild ductal proliferation and portal fibrosis. This was interpreted as suspicious for biliary atresia. Jaundice resolved gradually. In summary, patients who have intestinal excretion of radionuclide on Tc-99m DlSIDA hepatobiliary scintigraphy, biliary atresia can be ruled out. But the patients who do not have intestinal excretion of radionuclide should have further investigation by needle biopsy. Judicious use of Tc-99m DISIDA hepatobiliary scintigraphy and percutaneous needle biopsy can give a diagnostic accuracy of 95% or more in cases of infantile cholestasis.

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Stereotypes of the Single Women Held by University Students (대학생이 인지하는 독신여성에 대한 고정관념 -경남 및 전북지역의 대학생을 중심으로 -)

  • Yi, Yeong-Sug;Park, Kyung-Rhan
    • Journal of the Korean Home Economics Association
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    • v.41 no.10 s.188
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    • pp.173-184
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    • 2003
  • The purpose of this research is to identify stereotypes toward the single women(30-49 age) held by university students. Stereotypes toward the single women were examined at two levels: to assess students' beliefs about the traits of single women and to categorize the traits into stereotypes. The main results of this study were as follows: 1) Students reported 99 traits associated with the single women. 2) Hierarchical cluster analysis of the trait groupings revealed two high-level clusters: a cluster of 45 positive traits and a cluster of 54 negative traits. Within the positive and negative clusters, 10 middle-level categories, 4 positive categories(enjoy living affluently, independence-oriented, progressive, openhearted), and 6 negative categories(lack of vitality, pitiful, self-centered, picky, childish, self-defensive) were identified. This results suggested that young adults believed negative stereotypes are more typical than positive ones.

Study for Major Nutrients Sources of Food by Korean Nutrition Survey -II. Minerals and Vitamins- (국민영양조사를 이용한 영양소별 주요 공급식품에 관한 연구 -II. 무지길 및 비타민-)

  • 박미아
    • Journal of Nutrition and Health
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    • v.30 no.1
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    • pp.91-99
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    • 1997
  • We have studied the major food sources of minerals and vitamin based on the data from the National Nutrition Survey in 1993. The most important food sources was anchovy for calcium, spinach for vitamin A, and kimchi for vitamin C. The primary source of iron, thiamin, riboflavin and niacin was rice. Number of foods providing 90% of individual nutrient intake were 54 items for calcium, 40 items for iron, 20 items for vitamin A, 25 items for thiamin, 29 items for riboflavin, 39 items for niacin and 18 items for vitamin C. Among regions, amount of nutrients from same foods(10 more important food source) didn't show any significant differences (p>0.05) in minerals and vitamins studied. Over all rice was found to be the most important sources of minerals and vitamins.

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Feedback Active Noise Control Based Voice Enhancing Ear-Protection System

  • Moon, Seong-Pil;Chang, Tae-Gyu
    • Journal of Electrical Engineering and Technology
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    • v.12 no.4
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    • pp.1627-1633
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    • 2017
  • This paper proposes a voice enhancing ear-protection system which is based on feedback active noise control(FBANC). The proposed system selectively suppresses the background noise and preserves the talking voice by controlling the adaptive algorithm with the voice activity period detection module. The noise reduction performance of the proposed noise canceling algorithm is analytically derived for the two key performance affecting parameters, i.e., electro-acoustic coupling distance and noise bandwidth. The proposed system is also implemented with a floating-point DSP system and its performance is experimentally tested to compare with the analytically derived results. The achieved levels of noise reduction for the three different noise bandwidths cases, i.e., 10Hz, 50Hz, and 90Hz, are high to show 17.05dB, 10.54dB and 8.99dB, respectively. The feasibility of the proposed system is also shown by the peak noise reduction achieved more than 25dB while preserving the voice component in the frequency range between 200-800Hz.

A Study of Stress on the Family Caregivers for the Hospitalized Elderly (입원 노인을 돌보는 가족원의 스트레스에 관한 연구)

  • Kim Kang-MiJa
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.3 no.2
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    • pp.247-258
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    • 1996
  • This study explored the variables to influence the stress of the family caregivers providing care for the hospitalized elderly The subjects for this study were 104 family caregivers selected from the caregivers in the in patient departments of two major medical centers in Jeonju city. Data were collected from December 18th to 27th, 1995 using a Liker Scale Questionaire and interview. Data analyses included percentage, mean, standard deviation, t and F-test. Results were following : 1. The mean of this sample is 21.48, and the standard deviation is ${\pm}5.64$ in the perceived stress. The major variables to influence on the stress of caregivere for the hospitalized elderly were the stay (16-24hrs/day) in hospital(F=7.99, p=0.006), no other helpers(t=-2.56, P=.012), percieving severely on illness(F=3.90, P=.0232) perceiving moderately on physical health status(F=6.20, P=.0029). 2. Regarding the perceived social support of the family caregivers, the higher support the group perceived the lower stress(F=3.54, P=.0326).

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The Mental Health of Ethnic Minority Youths in South Korea and Its Related Environmental Factors: A Literature Review

  • Lee, Yeeun;Lee, Minji;Park, Subin
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.30 no.3
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    • pp.88-99
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    • 2019
  • Objectives: With increasing concerns for the rapidly growing minority population in South Korea, this literature review addressed a range of mental health risks among multiethnic youths (MY) in South Korea by 1) comparing mental health outcomes with those of native-born youths and 2) identifying multiple layers of relevant environmental factors, from family and school relationships to culture. Methods: We reviewed 54 studies that fulfilled specific inclusion criteria. Results: Multiple common risk/protective factors, including family separation, family relationship quality, parental socioeconomic and mental health status, social relationships at school, and cultural acceptance, were noted. Conclusion: In general, empirical evidence indicates that minority youths have relatively heightened risks for emotional and behavioral problems. Future studies must elucidate the complex interplay between multiple risk and protective factors and the long-term adaptation and mental health service utilization of MY.

Novel Detection Algorithm of The Upstroke of Pulse Waveform for Continuously Varying Contact Pressure Method (연속 가압방식의 맥파 측정방법을 위한 시작점 검출 알고리즘 개발)

  • Bae, Jang-Han;Jeon, Young-Ju;Kim, Jong-Yeol;Kim, Jae-Uk
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.49 no.2
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    • pp.46-54
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    • 2012
  • We propose a continuously varying contact pressure(CVCP)-adaptive feature extraction algorithm for pulse diagnostic analysis. The CVCP method measures the pulse waveform with continuously increasing contact pressure(CP). This method offer a high resolution signal of the pulse waveform amplitude(PWA) as a function of the contact pressure. Therefore it enables us to overcome the limitation of commercially available pulse-taking devices whose analysis rely on a few number of PWA-CP pairs. We show that an efficient feature extraction algorithm which covers the features of the CVCP-method can be developed by sequentially applying Fast Fourier Transform, peak detection by center-to-edges method, baseline drift removal, detection of the percussion wave upstroke by intersecting tangent method and detection of the analysis region. Finally, by a clinical study with 30 subjects, we show that our CVCP-adaptive feature extraction algorithm detected the upstroke with accuracy of 99.46% and sensitivity of 99.51%, which were about 4.82% and 2.46% increases respectively, compared to a conventional feature extraction method. The proposed CVCP method and the CVCP-adaptive feature extraction algorithm are expected to improve the accuracy in the pulse diagnostic algorithms such as floating/sunken pulse qualities and deficient/excess pulse qualities.

Performance comparison and evaluation of interferon-gamma assay kit for bovine tuberculosis diagnosis (소 결핵 진단을 위한 인터페론감마 검사 키트의 성능 비교 평가)

  • Hong, Leegon;Choi, Woojae;Ro, Younghye;Ahn, Sunmin;Kim, Eunkyung;Choe, Eunhee;Kim, Danil
    • Korean Journal of Veterinary Service
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    • v.43 no.4
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    • pp.201-209
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    • 2020
  • In Korea, bovine tuberculosis (bTB) is a representative zoonotic disease that causes considerable economic loss. In determining the positive bTB, the ELISA method for examining the amount of interferon-gamma (IFN-γ) is included in Korea's diagnostic standard method. Recently, commercially available BIONOTE TB-Feron ELISA Plus (TB-Feron Plus) that detects IFN-γ has been introduced. However, since the scientific basis for the performance is limited, we evaluated performance by comparing it with the results of another IFN-γ ELISA assay kit (BOVIGAM®) certified by Office International des Epizooties. In our research, 42 positive blood samples preliminarily tested with a tuberculin skin test and/or BOVIGAM® and 54 negative blood samples collected from three bTB free farms were subjected to IFN-γ assay using the TB-Feron Plus and the BOVIGAM®, respectively. The result shows that the sensitivity, specificity and accuracy were 81.0% (34/42), 100% (54/54), 91.7% (88/96) in TB-Feron Plus kit and 78.6% (33/42), 100% (54/54), 90.6% (87/96) in BOVIGAM® kit, respectively. Moreover, the overall accordance percentage of the two kits was 99.0% (95/96) and there was almost perfect agreement between two assays (Kappa=0.977, P<0.0001). Furthermore, additional studies confirmed that elevated lymphocyte numbers in blood did not interfere with the results of the TB-Feron Plus kit. And, delayed time from sampling to culture decreased the optical density (OD) value. Therefore, we concluded that the TB-Feron Plus kit was not inferior to BOVIGAM® in performance. High lymphocyte numbers in blood did not impact on TB-Feron Plus results, while delayed time before culture interfered with OD value.

Processing Characteristics of the Condensed Wastewater Resulting from Food Waste Disposal using a Submerged Polyethylene Hollow Fiber Membrane (음식물 소멸기에서 발생하는 응축폐수의 Polyethylene 침지형 중공사막을 이용한 처리 특성)

  • Ryu, Jae-Sang;Jeon, Tae-Bong;Kim, Jin-Ho;Chung, Kun-Yong
    • Membrane Journal
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    • v.20 no.2
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    • pp.127-134
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    • 2010
  • This study is conducted about the system that reduces organism after fermenting food waste from a food waste disposal equipment, divides gas made when food waste is fermented into gas and water, and then sends gas to a reactor again, condenses water, and apply it to the MBR system with submerged MF hollow fiber membranes. A submerged MF hollow fiber membrane module was installed to a food waste disposal equipment and a water treatment system made by Bio Hitech Co,. Ltd. to process food waste generated from a staff cafeteria in a H institute for 90 days. For initial seeding of a food waste disposal equipment, 305 kg of rice bran, chaff, and sawdust as well as 1,648 kg of food were input during the operation, and 1,600 L of condensed wastewater occurred. Fermented by-product after finishing running a food waste disposal equipment was 386 kg and its reduction was shown to be 80%. The organism was processed by applying submerged MF hollow fiber membrane module to the MBR system of condensed wastewater, and the result shows reduction rates were BOD 99.9%, COD 97.5%, SS 98.6%, T-N 54.6% and T-P 34.7% and the total colon bacillus was perfectly eliminated.

A study on Broad Quantification Calibration to various isotopes for Quantitative Analysis and its SUVs assessment in SPECT/CT (SPECT/CT 장비에서 정량분석을 위한 핵종 별 Broad Quantification Calibration 시행 및 SUV 평가를 위한 팬텀 실험에 관한 연구)

  • Hyun Soo, Ko;Jae Min, Choi;Soon Ki, Park
    • The Korean Journal of Nuclear Medicine Technology
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    • v.26 no.2
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    • pp.20-31
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    • 2022
  • Purpose Broad Quantification Calibration(B.Q.C) is the procedure for Quantitative Analysis to measure Standard Uptake Value(SUV) in SPECT/CT scanner. B.Q.C was performed with Tc-99m, I-123, I-131, Lu-177 respectively and then we acquired the phantom images whether the SUVs were measured accurately. Because there is no standard for SUV test in SPECT, we used ACR Esser PET phantom alternatively. The purpose of this study was to lay the groundwork for Quantitative Analysis with various isotopes in SPECT/CT scanner. Materials and Methods Siemens SPECT/CT Symbia Intevo 16 and Intevo Bold were used for this study. The procedure of B.Q.C has two steps; first is point source Sensitivity Cal. and second is Volume Sensitivity Cal. to calculate Volume Sensitivity Factor(VSF) using cylinder phantom. To verify SUV, we acquired the images with ACR Esser PET phantom and then we measured SUVmean on background and SUVmax on hot vials(25, 16, 12, 8 mm). SPSS was used to analyze the difference in the SUV between Intevo 16 and Intevo Bold by Mann-Whitney test. Results The results of Sensitivity(CPS/MBq) and VSF were in Detector 1, 2 of four isotopes (Intevo 16 D1 sensitivity/D2 sensitivity/VSF and Intevo Bold) 87.7/88.6/1.08, 91.9/91.2/1.07 on Tc-99m, 79.9/81.9/0.98, 89.4/89.4/0.98 on I-123, 124.8/128.9/0.69, 130.9, 126.8/0.71, on I-131, 8.7/8.9/1.02, 9.1/8.9/1.00 on Lu-177 respectively. The results of SUV test with ACR Esser PET phantom were (Intevo 16 BKG SUVmean/25mm SUVmax/16mm/12mm/8mm and Intevo Bold) 1.03/2.95/2.41/1.96/1.84, 1.03/2.91/2.38/1.87/1.82 on Tc-99m, 0.97/2.91/2.33/1.68/1.45, 1.00/2.80/2.23/1.57/1.32 on I-123, 0.96/1.61/1.13/1.02/0.69, 0.94/1.54/1.08/0.98/ 0.66 on I-131, 1.00/6.34/4.67/2.96/2.28, 1.01/6.21/4.49/2.86/2.21 on Lu-177. And there was no statistically significant difference of SUV between Intevo 16 and Intevo Bold(p>0.05). Conclusion Only Qualitative Analysis was possible with gamma camera in the past. On the other hand, it's possible to acquire not only anatomic localization, 3D tomography but also Quantitative Analysis with SUV measurements in SPECT/CT scanner. We could lay the groundwork for Quantitative Analysis with various isotopes; Tc-99m, I-123, I-131, Lu-177 by carrying out B.Q.C and could verify the SUV measurement with ACR phantom. It needs periodic calibration to maintain for precision of Quantitative evaluation. As a result, we can provide Quantitative Analysis on follow up scan with the SPECT/CT exams and evaluate the therapeutic response in theranosis.