• Archives of Pharmacal Research
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• v.18 no.1
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• pp.18-21
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• 1995

Poly(ethylene glycol)(PEG) macrocers teminated with acrylate groups and semi-interpenetrating polymer networks (IPNs) composed of poly-.epsilon.-capolactone(PCL) and PEG macromer were syntheswized with the aim of obtaining a bioerodible hydrogel that could be used to release drugs for implantable delivery system. Polymerization of PEG macromer resulted in the formation of cross-linked gels due to the multifunctionality of macromer. Non-crosslinked PCL chains were interpenetrated into the cross-linked three-dimensions networks of PEG. The IPNs, largw drug loading lower concentration of PEG macromer in the IPNs concentration and the higher molecular weight of PEG macromer. Also, 5-FU was more fast released than hydrocortisone to the increased water solubility.

• Bulletin of the Korean Chemical Society
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• v.25 no.8
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• pp.1241-1243
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• 2004

• ETRI Journal
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• v.33 no.6
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• pp.953-956
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• 2011

A novel dual-mode bandpass filter (BPF) using a dual spiral-shaped defected ground waveguide (DGW) resonator is proposed in this letter. The dual-mode characteristic of this filter is achieved by loading a defected T-shaped stub at the midline of the spiral-shaped DGW resonator. Also, non-orthogonal input and output feed-lines are adopted in the filter. Based on the compact DGW structure, a dual-mode BPF with central frequency of 1.5 GHz for the global positioning system is designed, fabricated, and measured. Measured results agree well with the predicted response and verify the proposed methodology.

• Bulletin of the Korean Chemical Society
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• v.34 no.8
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• pp.2321-2324
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• 2013

An improved hybrid solar cell was obtained by focusing on the effects of ligand for CdSe nanoparticles, in the active layers. The performance was compared by mixing nanoparticles capped with pyridine or oleic acid for the acceptor material into poly(3-hexylthiophene):[6,6]-phenyl C61 butyric acid methyl ester based active layer. The solar cells with pyridine capped CdSe nanoparticles showed a power conversion efficiency of 2.96% while oleic acid capped CdSe nanoparticles showed 2.85%, under AM 1.5G illumination. Formation of percolation pathways for carrier transport and a reduction in the hopping event resulted in better performance of pyridine capped nanoparticles.

• Structural Engineering and Mechanics
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• v.33 no.3
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• pp.339-355
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• 2009

The sealed, tuned liquid column gas damper (TLCGD) with gas-spring effect extends the frequency range of application up to about 5 Hz and efficiently increases the modal structural damping. In this paper the influence of several TLCGDs to reduce coupled translational and rotational vibrations of plan-asymmetric buildings under wind or seismic loads is investigated. The locations of the modal centers of velocity of rigidly assumed floors are crucial to select the design and the optimal position of the liquid absorbers. TLCGD's dynamics can be derived in detail using the extended non-stationary Bernoulli's equation for moving reference systems. Modal tuning of the TLCGD renders the optimal parameters by means of a geometrical transformation and in analogy to the classical tuned mass damper (TMD). Subsequently, fine-tuning is conveniently performed in the state space domain. Numerical simulations illustrate a significant reduction of the vibrations of plan-asymmetric buildings by the proposed TLCGDs.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.7 no.7
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• pp.1478-1482
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• 2003

In this paper. Rijndael cipher algorithm is implemented by a hardware. It was selected as the AES(Advanced Encryption Standard) by NIST. It has structure that round operation divided into 2 subrounds and subrounds are pipelined to calculate efficiently. It takes 5 clocks for one-round. The AES-128 cipher algorithm is implemented for hardware by ALTERA FPGA, and, analyzed the performance. The AES-128 cipher algorithm has approximately 424 Mbps encryption rate for 166Mhz max clock frequency. In case of decryption, it has 363 Mbps decryption rate fu 142Mhz max clock frequency. In case of cipher core, it has 320Mbps encryptionㆍdecryption rate for 125Mhz max clock frequency.

• Biomolecules & Therapeutics
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• v.30 no.5
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• pp.399-408
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• 2022

Diabetic cardiomyopathy (DCM) is described as abnormalities of myocardial structure and function in diabetic patients without other well-established cardiovascular factors. Although multiple pathological mechanisms involving in this unique myocardial disorder, mitochondrial dysfunction may play an important role in its development of DCM. Recently, considerable progresses have suggested that mitochondrial biogenesis is a tightly controlled process initiating mitochondrial generation and maintaining mitochondrial function, appears to be associated with DCM. Nonetheless, an outlook on the mechanisms and clinical relevance of dysfunction in mitochondrial biogenesis among patients with DCM is not completely understood. In this review, hence, we will summarize the role of mitochondrial biogenesis dysfunction in the development of DCM, especially the molecular underlying mechanism concerning the signaling pathways beyond the stimulation and inhibition of mitochondrial biogenesis. Additionally, the evaluations and potential therapeutic strategies regarding mitochondrial biogenesis dysfunction in DCM is also presented.

• Animal Bioscience
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• v.36 no.2_spc
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• pp.339-349
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• 2023

Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic cell nuclear transfer, cryopreservation, and nonsurgical embryo transfer. The extension of NBT in the new era of pig breeding depends on the synergistic effect of GE and reproductive biotechnologies; the outcome relies not only on scientific due diligence and operational excellence but also on the feasibility of application on farms to improve sustainability.

• Parasites, Hosts and Diseases
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• v.61 no.3
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• pp.231-239
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• 2023

Toxoplasma gondii is an intracellular parasitic organism affecting all warm-blooded vertebrates. Due to the unavailability of commercialized human T. gondii vaccine, many studies have been reported investigating the protective efficacy of pre-clinical T. gondii vaccines expressing diverse antigens. Careful antigen selection and implementing multifarious immunization strategies could enhance protection against toxoplasmosis in animal models. Although none of the available vaccines could remove the tissue-dwelling parasites from the host organism, findings from these pre-clinical toxoplasmosis vaccine studies highlighted their developmental potential and provided insights into rational vaccine design. We herein explored the progress of T. gondii vaccine development using DNA, protein subunit, and virus-like particle vaccine platforms. Specifically, we summarized the findings from the pre-clinical toxoplasmosis vaccine studies involving T. gondii challenge infection in mice published in the past 5 years.

• The Plant Pathology Journal
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• v.31 no.3
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• pp.305-309
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• 2015

After four years of cold storage, dimethachlon resistance of two laboratory-induced resistant Sclerotinia sclerotiorum isolates SCG7 and LA50 declined by 99.5% and 98.9%, respectively, and cross resistance to iprodione and procymidone also declined dramatically. Along with the decline of fungicide resistance, osmotic sensitivity to sodium chloride and glucose decreased tremendously; mycelial growth rate, sclerotia number and weight per potato dextrose agar (PDA) plate increased on average by 118.6%, 85. 5% and 64.5%, respectively; and virulence to detached leaves of oilseed rape increased by 72.7% on average. Significant negative correlations were detected between dimethachlon resistance levels and mycelial growth rate on PDA (r = -0.980, P = 0.021), and between resistance levels and lesion diameters on detached leaves of oilseed rape plants (r = -0.997, P = 0.002). These results have profound implications for assessing the potential risk for resistance development to dicarboximide fungicides in S. sclerotiorum.