• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2002.03a
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• pp.228-235
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• 2002

As the response spectrum method generally used in the earthquake resistant design is a linear method, the nonlinear behavior of a structure is to be reflected with a specific factor. Such factors are provided in the "Design Criteria for Roadwaybridges"as response modification factors and in the Eurocode 8, Part 2 as behavior factors. In this study a 5-span steel box bridge with single column piers is selected and the behavior factor is determined. The linear time history analyses are carried out with a simple linear model, where the nonlinear behavior of piers leading to the ductile failure mechanism is considered as predetermined characteristic curves.

• Bulletin of the Korean Chemical Society
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• v.27 no.5
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• pp.663-666
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• 2006

Carnosine, homocarnosine and anserine might act as anti-oxidants and free radical scavengers in vivo. In the present study, the protective effects of carnosine and related compounds on the $H_2O_2$-mediated cytochrome c modification were studied. Carnosine, homocarnosine and anserine significantly inhibited the oligomerization of cytchrome c induced by $H_2O_2$. All three compounds also inhibited the formation of carbonyl compound and dityrosine during the incubation of cytochrome c with $H_2O_2$. These compounds effectively inhibited the peroxidase activity in the cytchrome c treated with $H_2O_2$. The results suggested that carnosine, homocarnosine, and anserine might protect cytochrome c against $H_2O_2$-mediated oxidative damage through a free radical scavenging.

• KSBB Journal
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• v.11 no.2
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• pp.186-192
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• 1996

The effects of chemical modification on the enzymes' stability in polar organic solvents were studied with subtilisin Carlsberg in dimethylformamide-water mixtures as a model system. Three out of nine lysine residues of subtilisin Carlsberg were coupled to either trimellilic or pyromellitic anhydrides thereby, for each lysine residue modified, resulting in the net replacement of one basic amino group by two or three acidic carboxyl groups, respectively. In water at 60$^{\circ}C$, both trimellitic and pyromellitic anhydride-modified subtilisin Carlsberg showed increased thermostability by 2.6 times and 1.6 times, respectively, as compared to that of unmodified enzyme. In 70% dimethylformamide at 25$^{\circ}C$, however, only pyromellitic acrid was shown to enhance the stability of subtilisin Carlsberg by 5.5 times increasing the half life time of irreversible inactivation from 4.9hr for unmodified enzyme to 27.8hr for modified enzyme.

• Journal of applied mathematics & informatics
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• v.29 no.5_6
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• pp.1363-1379
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• 2011

Halpern iterative algorithm is one of the most cited in the literature of approximation of fixed points of nonexpansive mappings. Different authors modified this iterative algorithm in Banach spaces to approximate fixed points of nonexpansive mappings. One of which is Hu [8] and Yao et al [21] modification of Halpern iterative algorithm for nonexpansive mappings in Banach spaces. It is the purpose of this paper to thoroughly analyze this modification and its convergence conditions. Unfortunately, Hu [8] and Yao et al [21] control conditions imposed on the modified Halpern iterative algorithm to have strong convergence are found to be not sufficient. In this paper, counterexamples are constructed to prove that the strong convergence conditions of Hu [8] and Yao et al [21] are not sufficient. It is also proved that with some additional conditions on the control parameters, strong convergence of the defined iterative algorithm is obtained in different Banach space settings.

• Journal of the Korean Vacuum Society
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• v.8 no.2
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• pp.157-164
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• 1999

The post ion implantation has been applied to modify early-grown BN layer and improve the adhesion of the BN films. The effect of ion implantation doses on microstructure and interlayer was investigated by FTIR and HRTEM. And the hardness and delamination life time of N+-implanted BN films were measured. With increasing the ion dose up to $5.0\times10^{15}\textrm{atoms/cm}^2$,the change of IR spectrum is observed. At $5.0\times10^{16}\textrm{atoms/cm}^2$, a drastic transition of cubic phase into hexagonal phase is detected. The change of microstructure of early-grown layers by ion implantation is confirmed using HRTEM. Both microhardness and delamination life time of BN films increase with ion dose. The modification model of early-grown BN layers is briefly discussed based on the displacement per atom and excess boron in the BN film induced by ion irradiation.

• BMB Reports
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• v.30 no.2
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• pp.113-118
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• 1997

Aspartase from Hafnia alvei was inactivated by N-ethylmaleimide (NEM) and 5,5' -Dithiobis-(2-znitrobenzoic acid) (DTNB) following pseudo-first order kinetics. Their apparent reaction orders were 0.83 and 0.50 for NEM and DTNB modifications, respectively, indicating that inactivation was due to a sulfhydryl group in the active site of aspartase and participation of the sulfhydryl group in an essential step in the catalytic reaction. When aspartase was modified by DTNB, the enzyme activity was restored by dithiothreitol treatment, indicating that cysteine residuetsl islarel possibly at or near the active site. The pH-dependence of the inactivation rate by NEM suggested that an amino acid residue having pK value of 8.3 was involved in the inactivation. When aspartase was incubated with NEM and L-aspartate together, L-aspartate markedly protected the enzyme from inactivation by NEM, but the other reagents used did not.

• Carbon letters
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• v.2 no.3_4
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• pp.165-169
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• 2001

Modification of C/C composite bipolar plate for improving electrical conductivity was carried out by addition of electroconductive carbon black (EC-CB). Carbon black was carefully mixed to methanol-containing phenolic resin, impregnated into 2D-carbon fabrics, hot pressed and then carbonized to obtain composite plate. Inclusion of electro-conductive carbon black enhanced the electrical conductivity of the C/C composites by increasing the conduction path. Addition of 10 vol% carbon black increased the electrical conductivity from 5.5/${\Omega}cm$ to 32/${\Omega}cm$ and reduced the crack formation by filling effect, resulting in the increase of flexural properties of composite plate. However, at carbon black content over 10 vol%, flexural properties decreased by delaminating role of excess carbon black at the interface in C/C composites.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.5
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• pp.765-771
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• 2017

This paper presents concurrent design methods of surface permanent magnet synchronous machines for saliency-tracking self-sensing position estimation. Magnetic saliency for the self-sensing is created by stator pole saturation due to the rotor zigzag leakage flux. The power conversion properties such as saliency ratio, torque ripple, and efficiency vary according to motor design. The property change due to design modification is analysed by using finite element analysis, and with the appropriate design modification, proper saliency is created while preserving their power conversion capabilities.

• The Journal of Asian Finance, Economics and Business
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• v.5 no.2
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• pp.95-104
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• 2018

The purpose of this study is to investigate the impact of narcissism on employees' social media addiction and how it influences their job satisfaction and organizational commitment. And this study explores if perceived organizational support can moderate the relationship between narcissism and social media addiction. For this, this study collected data from 285 employees in Korean companies through a survey method and uses SPSS 18.0 for hierarchical regression analysis in the hypothesis test. First, organizational politics increases mood modification, withdrawal and tolerance among the sub-factors of social media addiction. Second, each phenomena of social media service addiction such as salience, withdrawal and tolerance decrease each relevant factors of job satisfaction and organizational commitment. Third, withdrawal and tolerance among the sub-factors of social media addiction play the mediating roles between narcissism and each relevant factors of job satisfaction/organizational commitment. Finally, perceived organizational support decrease the effect of narcissism on mood modification, withdrawal and tolerance among the sub-factors of social media addiction. This study provides some of managerial implications to corporate executives who try to manage organizational attitudes.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.199-204
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• 2005

Background: ADP-ribosyl pyrophosphatases (ADPRase) has been known to catalyze the hydrolysis of ADP-ribose to ribose-5-phosphate and AMP. The role of ADPRase has been suggested to sanitize the cell by removing potentially toxic ADP-ribose. In this study, we examined the effect of nitric oxide on ADPRase activity in macrophages. Methods: ADPRase activity was measured in NO-inducing J774 cells. For in vitro experiments, recombinant human ADPRase was prepared in bacteria. Results: ADPRase activity was increased by the treatment of exogenous NO generating reagent, sodium nitroprusside (SNP), in J774 cells. The increased ADPRase activity was mediated by the post-translational modification, likely to cause cADP-ribosylation via nitrosylation of cysteine residue on the enzyme. The stimulation with endogeneous NO inducers, $TNF-{\alpha}/IFN-{\gamma}$, also increased ADPRase activity through NO synthesis. Futhermore, ADPRase activity may be mediated by the post-translational modification of ADPRase, ADP-ribosylation. Conclusion: These results indicate that NO synthesized by macrophage activation plays a critical role in the increase in ADPRase activity following ADP-ribose metabolism.